메뉴 건너뛰기




Volumn 107, Issue , 2012, Pages 383-407

Analyses of C. elegans Fat Metabolic Pathways

Author keywords

Freeze thawing; Homeostatic; Quantitation; Storage; Triglyceride; Xenobiotic

Indexed keywords


EID: 84855465409     PISSN: 0091679X     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-394620-1.00013-8     Document Type: Chapter
Times cited : (32)

References (44)
  • 1
    • 0037448528 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
    • Ashrafi K., et al. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 2003, 421:268-272.
    • (2003) Nature , vol.421 , pp. 268-272
    • Ashrafi, K.1
  • 2
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction an purification
    • Bligh E.G., Dyer W.J. A rapid method of total lipid extraction an purification. Can. J. Biochem. Physiol. 1959, 37(8):911-917.
    • (1959) Can. J. Biochem. Physiol. , vol.37 , Issue.8 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 4
    • 70449560405 scopus 로고    scopus 로고
    • The influence of bacterial diet on fat storage in C. elegans
    • Brooks K.K., et al. The influence of bacterial diet on fat storage in C. elegans. PLoS ONE 2009, 4:e7545.
    • (2009) PLoS ONE , vol.4
    • Brooks, K.K.1
  • 5
    • 0242457355 scopus 로고    scopus 로고
    • Staining methods applied to glycol methacrylate embedded tissue sections
    • Cerri P.S., Sasso-Cerri E. Staining methods applied to glycol methacrylate embedded tissue sections. Micron. 2003, 34:365-372.
    • (2003) Micron. , vol.34 , pp. 365-372
    • Cerri, P.S.1    Sasso-Cerri, E.2
  • 6
    • 48749104350 scopus 로고    scopus 로고
    • Hydrophobic characterization of intracellular lipids in situ by Nile Red red/yellow emission ratio
    • Diaz G., et al. Hydrophobic characterization of intracellular lipids in situ by Nile Red red/yellow emission ratio. Micron. 2008, 39:819-824.
    • (2008) Micron. , vol.39 , pp. 819-824
    • Diaz, G.1
  • 7
    • 56249136680 scopus 로고    scopus 로고
    • Coherent anti-stokes Raman scattering microscopy: chemical imaging for biology and medicine
    • Evans C.L., Xie X.S. Coherent anti-stokes Raman scattering microscopy: chemical imaging for biology and medicine. Annu. Rev. Anal. Chem. (Palo Alto Calif). 2008, 1:883-909.
    • (2008) Annu. Rev. Anal. Chem. (Palo Alto Calif). , vol.1 , pp. 883-909
    • Evans, C.L.1    Xie, X.S.2
  • 8
    • 0022391125 scopus 로고
    • Application of Nile red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: comparison with oil red O
    • Fowler S.D., Greenspan P. Application of Nile red, a fluorescent hydrophobic probe, for the detection of neutral lipid deposits in tissue sections: comparison with oil red O. J. Histochem. Cytochem. 1985, 33:833-836.
    • (1985) J. Histochem. Cytochem. , vol.33 , pp. 833-836
    • Fowler, S.D.1    Greenspan, P.2
  • 9
    • 0036435902 scopus 로고    scopus 로고
    • Deformation of lipid droplets in fixed samples
    • Fukumoto S., Fujimoto T. Deformation of lipid droplets in fixed samples. Histochem. Cell Biol. 2002, 118:423-428.
    • (2002) Histochem. Cell Biol. , vol.118 , pp. 423-428
    • Fukumoto, S.1    Fujimoto, T.2
  • 11
    • 57649116078 scopus 로고    scopus 로고
    • The gregarious lipid droplet
    • Goodman J.M. The gregarious lipid droplet. J. Biol. Chem. 2008, 283:28005-28009.
    • (2008) J. Biol. Chem. , vol.283 , pp. 28005-28009
    • Goodman, J.M.1
  • 12
    • 0021816546 scopus 로고
    • Spectrofluorometric studies of the lipid probe, nile red
    • Greenspan P., Fowler S.D. Spectrofluorometric studies of the lipid probe, nile red. J. Lipid Res. 1985, 26:781-789.
    • (1985) J. Lipid Res. , vol.26 , pp. 781-789
    • Greenspan, P.1    Fowler, S.D.2
  • 13
    • 48149109399 scopus 로고    scopus 로고
    • Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding
    • Greer E.R., et al. Neural and molecular dissection of a C. elegans sensory circuit that regulates fat and feeding. Cell Metab. 2008, 8:118-131.
    • (2008) Cell Metab. , vol.8 , pp. 118-131
    • Greer, E.R.1
  • 14
    • 33750986182 scopus 로고    scopus 로고
    • The neuronal ceroid-lipofuscinoses: from past to present
    • Haltia M. The neuronal ceroid-lipofuscinoses: from past to present. Biochim. Biophys. Acta 2006, 1762:850-856.
    • (2006) Biochim. Biophys. Acta , vol.1762 , pp. 850-856
    • Haltia, M.1
  • 15
    • 35548956009 scopus 로고    scopus 로고
    • Monitoring of lipid storage in Caenorhabditis elegans using coherent anti-Stokes Raman scattering (CARS) microscopy
    • Hellerer T., et al. Monitoring of lipid storage in Caenorhabditis elegans using coherent anti-Stokes Raman scattering (CARS) microscopy. Proc. Natl. Acad. Sci. USA 2007, 104:14658-14663.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 14658-14663
    • Hellerer, T.1
  • 16
    • 65349113758 scopus 로고    scopus 로고
    • IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans
    • Jo H., et al. IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Cell Metab. 2009, 9:440-448.
    • (2009) Cell Metab. , vol.9 , pp. 440-448
    • Jo, H.1
  • 17
    • 67650305511 scopus 로고    scopus 로고
    • Caenorhabditis elegans as an emerging model for studying the basic biology of obesity
    • Jones K., Ashrafi K. Caenorhabditis elegans as an emerging model for studying the basic biology of obesity. Dis. Models Mech. 2009, 2:224-229.
    • (2009) Dis. Models Mech. , vol.2 , pp. 224-229
    • Jones, K.1    Ashrafi, K.2
  • 18
    • 65949103405 scopus 로고    scopus 로고
    • Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1
    • Jones K.T., et al. Rictor/TORC2 regulates Caenorhabditis elegans fat storage, body size, and development through sgk-1. PLoS Biol. 2009, 7:e60.
    • (2009) PLoS Biol. , vol.7
    • Jones, K.T.1
  • 19
    • 0030813398 scopus 로고    scopus 로고
    • Daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura K.D., et al. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 1997, 277:942-946.
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1
  • 20
    • 77952331856 scopus 로고    scopus 로고
    • Triacylglycerol homeostasis: insights from yeast
    • Kohlwein S.D. Triacylglycerol homeostasis: insights from yeast. J. Biol. Chem. 2010, 285:15663-15667.
    • (2010) J. Biol. Chem. , vol.285 , pp. 15663-15667
    • Kohlwein, S.D.1
  • 21
    • 77951926114 scopus 로고    scopus 로고
    • Label-free quantitative analysis of lipid metabolism in living Caenorhabditis elegans
    • Le T.T., et al. Label-free quantitative analysis of lipid metabolism in living Caenorhabditis elegans. J. Lipid Res. 2010, 51:672-677.
    • (2010) J. Lipid Res. , vol.51 , pp. 672-677
    • Le, T.T.1
  • 22
    • 34249310709 scopus 로고    scopus 로고
    • Cytochrome P450s and short-chain dehydrogenases mediate the toxicogenomic response of PCB52 in the nematode Caenorhabditis elegans
    • Menzel R., et al. Cytochrome P450s and short-chain dehydrogenases mediate the toxicogenomic response of PCB52 in the nematode Caenorhabditis elegans. J. Mol. Biol. 2007, 370:1-13.
    • (2007) J. Mol. Biol. , vol.370 , pp. 1-13
    • Menzel, R.1
  • 23
    • 55949083488 scopus 로고    scopus 로고
    • Thin-layer chromatography. Curr. Protoc. Nucleic Acid Chem. Appendix, 3D.
    • Meyers, C.L., and Meyers, D.J. (2008). Thin-layer chromatography. Curr. Protoc. Nucleic Acid Chem. Appendix, 3D.
    • (2008)
    • Meyers, C.L.1    Meyers, D.J.2
  • 24
    • 77954068415 scopus 로고    scopus 로고
    • The genetics of obesity and the metabolic syndrome
    • Monda K.L., et al. The genetics of obesity and the metabolic syndrome. Endocr. Metab. Immune Disord. Drug Targets 2010, 10:86-108.
    • (2010) Endocr. Metab. Immune Disord. Drug Targets , vol.10 , pp. 86-108
    • Monda, K.L.1
  • 25
    • 70849108761 scopus 로고    scopus 로고
    • Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans
    • Morck C., et al. Statins inhibit protein lipidation and induce the unfolded protein response in the non-sterol producing nematode Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 2009, 106:18285-18290.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 18285-18290
    • Morck, C.1
  • 26
    • 33748931457 scopus 로고    scopus 로고
    • Central nervous system control of food intake and body weight
    • Morton G.J., et al. Central nervous system control of food intake and body weight. Nature 2006, 443:289-295.
    • (2006) Nature , vol.443 , pp. 289-295
    • Morton, G.J.1
  • 27
    • 67349256839 scopus 로고    scopus 로고
    • C. elegans fat storage and metabolic regulation
    • Mullaney B.C., Ashrafi K. C. elegans fat storage and metabolic regulation. BBA - Mol. Cell Biol. Lipids 2009, 1791:474-478.
    • (2009) BBA - Mol. Cell Biol. Lipids , vol.1791 , pp. 474-478
    • Mullaney, B.C.1    Ashrafi, K.2
  • 28
    • 70350365111 scopus 로고    scopus 로고
    • C. elegans major fats are stored in vesicles distinct from lysosome-related organelles
    • O'Rourke E.J., et al. C. elegans major fats are stored in vesicles distinct from lysosome-related organelles. Cell Metab. 2009, 10:430-435.
    • (2009) Cell Metab. , vol.10 , pp. 430-435
    • O'Rourke, E.J.1
  • 29
    • 53549087498 scopus 로고    scopus 로고
    • Triglyceride containing lipid droplets and lipid droplet-associated proteins
    • Olofsson S.O., et al. Triglyceride containing lipid droplets and lipid droplet-associated proteins. Curr. Opin. Lipidol. 2008, 19:441-447.
    • (2008) Curr. Opin. Lipidol. , vol.19 , pp. 441-447
    • Olofsson, S.O.1
  • 30
    • 50049117073 scopus 로고    scopus 로고
    • A 13C isotope labeling strategy reveals the influence of insulin signaling on lipogenesis in C. elegans
    • Perez C.L., Van Gilst M.R. A 13C isotope labeling strategy reveals the influence of insulin signaling on lipogenesis in C. elegans. Cell Metab. 2008, 8:266-274.
    • (2008) Cell Metab. , vol.8 , pp. 266-274
    • Perez, C.L.1    Van Gilst, M.R.2
  • 31
    • 0028152492 scopus 로고
    • Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein
    • Schaffer J.E., Lodish H.F. Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell 1994, 79:427-436.
    • (1994) Cell , vol.79 , pp. 427-436
    • Schaffer, J.E.1    Lodish, H.F.2
  • 32
    • 67349096844 scopus 로고    scopus 로고
    • Endolysosomal phospholipidosis and cytosolic lipid droplet storage and release in macrophages
    • Schmitz G., Grandl M. Endolysosomal phospholipidosis and cytosolic lipid droplet storage and release in macrophages. Biochim. Biophys. Acta 2009, 1791:524-539.
    • (2009) Biochim. Biophys. Acta , vol.1791 , pp. 524-539
    • Schmitz, G.1    Grandl, M.2
  • 33
    • 33947158693 scopus 로고    scopus 로고
    • Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle
    • Schroeder L.K., et al. Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle. Mol. Biol. Cell 2007, 18:995-1008.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 995-1008
    • Schroeder, L.K.1
  • 34
    • 34748850786 scopus 로고    scopus 로고
    • Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
    • Schulz T.J., et al. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab. 2007, 6:280-293.
    • (2007) Cell Metab. , vol.6 , pp. 280-293
    • Schulz, T.J.1
  • 35
    • 61449244533 scopus 로고    scopus 로고
    • Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
    • Soukas A.A., et al. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans. Genes Dev. 2009, 23:496-511.
    • (2009) Genes Dev. , vol.23 , pp. 496-511
    • Soukas, A.A.1
  • 36
    • 67651250036 scopus 로고    scopus 로고
    • How the intestinal peptide transporter PEPT-1 contributes to an obesity phenotype in Caenorhabditits elegans
    • Spanier B., et al. How the intestinal peptide transporter PEPT-1 contributes to an obesity phenotype in Caenorhabditits elegans. PLoS ONE 2009, 4:e6279.
    • (2009) PLoS ONE , vol.4
    • Spanier, B.1
  • 37
    • 44349100977 scopus 로고    scopus 로고
    • Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms
    • Srinivasan S., et al. Serotonin regulates C. elegans fat and feeding through independent molecular mechanisms. Cell Metab. 2008, 7:533-544.
    • (2008) Cell Metab. , vol.7 , pp. 533-544
    • Srinivasan, S.1
  • 38
    • 33646777076 scopus 로고    scopus 로고
    • Lipid droplets are present in amyloid deposits in familial amyloidotic polyneuropathy and dialysis related amyloidosis
    • Sun X., et al. Lipid droplets are present in amyloid deposits in familial amyloidotic polyneuropathy and dialysis related amyloidosis. Amyloid 2006, 13:20-23.
    • (2006) Amyloid , vol.13 , pp. 20-23
    • Sun, X.1
  • 39
    • 0141672132 scopus 로고    scopus 로고
    • Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism
    • Teixeira L., et al. Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism. Mech. Dev. 2003, 120:1071-1081.
    • (2003) Mech. Dev. , vol.120 , pp. 1071-1081
    • Teixeira, L.1
  • 40
    • 65449155208 scopus 로고    scopus 로고
    • Chemical analysis in vivo and in vitro by Raman spectroscopy - from single cells to humans
    • Wachsmann-Hogiu S., et al. Chemical analysis in vivo and in vitro by Raman spectroscopy - from single cells to humans. Curr. Opin. Biotechnol. 2009, 20:63-73.
    • (2009) Curr. Opin. Biotechnol. , vol.20 , pp. 63-73
    • Wachsmann-Hogiu, S.1
  • 41
    • 63749112313 scopus 로고    scopus 로고
    • Fat synthesis and adiposity regulation in Caenorhabditis elegans
    • Watts J.L. Fat synthesis and adiposity regulation in Caenorhabditis elegans. Trends Endocrinol. Metab. 2009, 20:58-65.
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 58-65
    • Watts, J.L.1
  • 42
    • 0037197901 scopus 로고    scopus 로고
    • Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans
    • Watts J.L., Browse J. Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 2002, 99:5854-5859.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5854-5859
    • Watts, J.L.1    Browse, J.2
  • 43
    • 84858043420 scopus 로고    scopus 로고
    • Microscopic analysis of lipid droplet metabolism and dynamics in yeast
    • Wolinski H., Kohlwein S.D. Microscopic analysis of lipid droplet metabolism and dynamics in yeast. Methods Mol. Biol. 2008, 457:151-163.
    • (2008) Methods Mol. Biol. , vol.457 , pp. 151-163
    • Wolinski, H.1    Kohlwein, S.D.2
  • 44
    • 77949524057 scopus 로고    scopus 로고
    • Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans
    • Zhang S.O., et al. Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA. 2010, 107:4640-4645.
    • (2010) Proc. Natl. Acad. Sci. USA. , vol.107 , pp. 4640-4645
    • Zhang, S.O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.