RROP2186-533: A novel Peptide antigen for detection of IgM antibodies against Toxoplasma gondii

Foodborne Pathogens and Disease

Volumn 9, Issue 1, 2012, Pages 7-12

  Liu, Lili ^a   Liu, Tingting ^a   Yu, Li ^a   Cai, Yihong ^a   Zhang, Aimei ^a   Xu, Xiucai ^a   Luo, Qingli ^a   Hu, Yuansheng ^a   Song, Wenjian ^b   Lun, Zhaorong ^c,d   Lu, Fangli ^d   Wang, Yong ^e   Shen, Jilong ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b JIANGHAN UNIVERSITY   (China)

^c School of Life Sciences   (China)

^d SUN YAT SEN UNIVERSITY   (China)

^e NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; PEPTIDE; RECOMBINANT ANTIGEN; RROP2 186-53; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY DETECTION; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOBLOTTING; IMMUNOREACTIVITY; MALE; MASS SPECTROMETRY; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TOXOPLASMA GONDII; TOXOPLASMOSIS; TWO DIMENSIONAL ELECTROPHORESIS;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIBODY SPECIFICITY; ANTIGENS, PROTOZOAN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN M; MEMBRANE PROTEINS; PEPTIDES; PREGNANCY; PREGNANCY COMPLICATIONS, PARASITIC; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; TOXOPLASMA; TOXOPLASMOSIS; TOXOPLASMOSIS, CONGENITAL;

MAMMALIA; TOXOPLASMA; TOXOPLASMA GONDII;

EID: 84855462626     PISSN: 15353141     EISSN: 15567125     Source Type: Journal    
DOI: 10.1089/fpd.2011.0942     Document Type: Article

References (13)

1. Beckers CJ, Dubremetz JF, Mercereau-Puijalon O, et al. The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm. J Cell Biol 1994;127:947-961. (Pubitemid 24355984)
2. Bobic B, Sibalic D, and Djurkovic-Djakovic O. High levels of IgM antibodies specific for Toxoplasma gondii in pregnancy 12 years after primary toxoplasma infection. Case report. Gynecol Obstet Invest 1991;31:182-184.
3. Galvan-Ramirez ML, Madriz Elisondo AL, Rico Torres CP, et al. Frequency of Toxoplasma gondii in pork meat in Ocotlan, Jalisco, Mexico. J Food Prot 2010;73:1121-1123.
4. Habib FS, Ali NM, El-Kadery AA, et al. Sequential recognition of antigenic markers of Toxoplasma gondii tachyzoite by pooled sera of mice with experimental toxoplasmosis. Parasitol Res 2011;108:151-160.
5. Liang L, Doskaya M, Juarez S, et al. Identification of potential serodiagnostic and subunit vaccine antigens by antibody profiling of toxoplasmosis cases in Turkey. Mol Cell Proteomics 2011;10:M110 006916.
6. Liesenfeld O, Press C, Montoya JG, et al. False-positive results in immunoglobulin M (IgM) Toxoplasma antibody tests and importance of confirmatory testing: the Platelia Toxo IgM test. J Clin Microbiol 1997;35:174-178. (Pubitemid 26422649)
7. Martin V, Arcavi M, Santillan G, et al. Detection of human Toxoplasma-specific immunoglobulins A, M, and G with a recombinant Toxoplasma gondii rop2 protein. Clin Diagn Lab Immunol 1998;5:627-631. (Pubitemid 29030757)
8. Montoya JG and Liesenfeld O. Toxoplasmosis. Lancet 2004; 363:1965-1976. (Pubitemid 38759657)
9. Saavedra R, Becerril MA, Dubeaux C, et al. Epitopes recognized by human T lymphocytes in the ROP2 protein antigen of Toxoplasma gondii. Infect Immun 1996;64:3858-3862. (Pubitemid 26298715)
10. Van Gelder P, Bosman F, de Meuter F, et al. Serodiagnosis of toxoplasmosis by using a recombinant form of the 54-kilodalton rhoptry antigen expressed in Escherichia coli. J Clin Microbiol 1993;31:9-15. (Pubitemid 23006570)
11. Verhofstede C, Van Renterghem L, and Plum J. Comparison of six commercial enzyme linked immunosorbent assays for detecting IgM antibodies against Toxoplasma gondii. J Clin Pathol 1989;42:1285-1290. (Pubitemid 20035917)
12. Wilson M, Remington JS, Clavet C, et al. Evaluation of six commercial kits for detection of human immunoglobulin M antibodies to Toxoplasma gondii. The FDA Toxoplasmosis Ad Hoc Working Group. J Clin Microbiol 1997;35:3112-3115. (Pubitemid 27505729)
13. Zhong ZR, Zhou HB, Li XY, et al. Serological proteome-oriented screening and application of antigens for the diagnosis of Schistosomiasis japonica. Acta Trop 2010;116:1-8.