Analyses of donor-derived keratinocytes in hairy and nonhairy skin biopsies of female patients following allogeneic male bone marrow transplantation

Stem Cells and Development

Volumn 21, Issue 1, 2012, Pages 152-157

  Nemeth, Krisztian ^a,b   Key, Sharon ^a   Bottlik, Gyula ^b   Masszi, Tamas ^c   Mezey, Eva ^a   Karpati, Sarolta ^b  

^a National Institutes of Dental and Craniofacial Research   (United States)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c Szent Laszlo Hospital   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN; KI 67 ANTIGEN;

ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; BACK; CELL PROLIFERATION; CHIMERA; CLINICAL ARTICLE; CONTROLLED STUDY; DONOR; ENGRAFTMENT; EPIDERMIS; FEMALE; HEMATOLOGIC MALIGNANCY; HLA SYSTEM; HUMAN; HUMAN TISSUE; HYBRIDIZATION; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCALP; SKIN BIOPSY; Y CHROMOSOME;

ADULT; BACK; BIOPSY; BONE MARROW TRANSPLANTATION; CHIMERA; CHROMOSOMES, HUMAN, Y; FEMALE; HEMATOLOGIC NEOPLASMS; HUMANS; KERATINOCYTES; KERATINS; MALE; MIDDLE AGED; SCALP; SKIN; TISSUE DONORS; TRANSPLANTATION, HOMOLOGOUS;

EID: 84855449996     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2010.0593     Document Type: Article

References (25)

1. Blanpain C, WE Lowry, A Geoghegan, L Polak and E Fuchs. 2004). Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118:635-648. (Pubitemid 39179715)
2. Fuchs E and S Raghavan. 2002). Getting under the skin of epidermal morphogenesis. Nat Rev Genet 3:199-209. (Pubitemid 34506588)
3. Verstappen J, C Katsaros, R Torensma and JW Von den Hoff. 2009). A functional model for adult stem cells in epithelial tissues. Wound Repair Regen 17:296-305.
4. Mezey E, S Key, G Vogelsang, I Szalayova, GD Lange and B Crain. 2003). Transplanted bone marrow generates new neurons in human brains. Proc Natl Acad Sci U S A 100: 1364-1369. (Pubitemid 36184007)
5. Abbas O and M Mahalingam. 2009). Epidermal stem cells: practical perspectives and potential uses. Br J Dermatol 161:228-236.
6. Blanpain C and E Fuchs. 2009). Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 10:207-217.
7. Fuchs E. 2009). Finding one s niche in the skin. Cell Stem Cell 4:499-502.
8. Krause DS, ND Theise, MI Collector, O Henegariu, S Hwang, R Gardner, S Neutzel and SJ Sharkis. 2001). Multiorgan, multi-lineage engraftment by a single bone marrowderived stem cell. Cell 105:369-377. (Pubitemid 32455343)
9. Sasaki M, R Abe, Y Fujita, S Ando, D Inokuma and H Shimizu. 2008). Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. J Immunol 180:2581-2587.
10. Brittan M, KM Braun, LE Reynolds, FJ Conti, AR Reynolds, R Poulsom, MR Alison, NA Wright and KM Hodivala-Dilke. 2005). Bone marrow cells engraft within the epidermis and proliferate in vivo with no evidence of cell fusion. J Pathol 205:1-13. (Pubitemid 40029087)
11. Trempus CS, RJ Morris, CD Bortner, G Cotsarelis, RS Faircloth, JM Reece and RW Tennant. 2003). Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. J Invest Dermatol 120:501-511. (Pubitemid 36343991)
12. Kloepper JE, S Tiede, J Brinckmann, DP Reinhardt, W Meyer, R Faessler and R Paus. 2008). Immunophenotyping of the human bulge region: The quest to define useful in situ markers for human epithelial hair follicle stem cells and their niche. Exp Dermatol 17:592-609. (Pubitemid 351803082)
13. Hoang MP, M Keady and M Mahalingam. 2009). Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia. Br J Dermatol 160:609-615.
14. Poblet E, F Jimenez, JM Godinez, A Pascual-Martin and A Izeta. 2006). The immunohistochemical expression of CD34 in human hair follicles: a comparative study with the bulge marker CK15. Clin Exp Dermatol 31:807-812. (Pubitemid 44563401)
15. Deng W, Q Han, L Liao, C Li,WGe, Z Zhao, S You, H Deng, F Murad and RC Zhao. 2005). Engrafted bone marrow-derived flk-(1 + ) mesenchymal stem cells regenerate skin tissue. Tissue Eng 11:110-119. (Pubitemid 40515179)
16. Korbling M, RL Katz, A Khanna, AC Ruifrok, G Rondon, M Albitar, RE Champlin and Z Estrov. 2002). Hepatocytes and epithelial cells of donor origin in recipients of peripheralblood stem cells. N Engl J Med 346:738-746. (Pubitemid 34983994)
17. Murata H, A Janin, C Leboeuf, J Soulier, E Gluckman, V Meignin and G Socie. 2007). Donor-derived cells and human graft-versus-host disease of the skin. Blood 109:2663-2665. (Pubitemid 46425918)
18. Suzuki T, M Nishida, S Futami, K Fukino, T Amaki, K Aizawa, S Chiba, H Hirai, K Maekawa and R Nagai. 2003). Neoendothelialization after peripheral blood stem cell transplantation in humans: a case report of a Tokaimura nuclear accident victim. Cardiovasc Res 58:487-492. (Pubitemid 36570407)
19. Hematti P, EM Sloand, CA Carvallo, MR Albert, CL Yee, MM Fuehrer, JK Blancato, WG Kearns, JA Barrett, RW Childs, JC Vogel and CE Dunbar. 2002). Absence of donorderived keratinocyte stem cells in skin tissues cultured from patients after mobilized peripheral blood hematopoietic stem cell transplantation. Exp Hematol 30:943-949. (Pubitemid 34838896)
20. Imanishi D, Y Miyazaki, R Yamasaki, Y Sawayama, J Taguchi, H Tsushima, T Fukushima, S Yoshida, H Sasaki, T Hata and M Tomonaga. 2007). Donor-derived DNA in fingernails among recipients of allogeneic hematopoietic stem-cell transplants. Blood 110:2231-2234. (Pubitemid 47523139)
21. Pearce L, ZY Lim, M Usai, AY Ho, GJ Mufti and A Pagliuca. 2008). Mixed donor chimaerism in recipient fingernails following reduced-intensity conditioning haematopoietic SCT. Bone Marrow Transplant 42:361-362.
22. Borue X, S Lee, J Grove, EL Herzog, R Harris, T Diflo, E Glusac, K Hyman, ND Theise and DS Krause. 2004). Bone marrow-derived cells contribute to epithelial engraftment during wound healing. Am J Pathol 165:1767-1772. (Pubitemid 39435173)
23. Tran SD, SR Pillemer, A Dutra, AJ Barrett, MJ Brownstein, S Key, E Pak, RA Leakan, A Kingman, KM Yamada, BJ Baum and E Mezey. 2003). Differentiation of human bone marrow- derived cells into buccal epithelial cells in vivo: a molecular analytical study. Lancet 361:1084-1088. (Pubitemid 36369561)
24. Belleudi F, V Purpura, C Scrofani, F Persechino, L Leone and MR Torrisi. 2011). Expression and signaling of the tyrosine kinase FGFR2b/KGFR regulates phagocytosis and melanosome uptake in human keratinocytes. FASEB J 25:170-181.
25. Sharlow ER, CS Paine, L Babiarz, M Eisinger, S Shapiro and M Seiberg. 2000). The protease-activated receptor-2 upregulates keratinocyte phagocytosis. J Cell Sci 113 (Pt 17): 3093-3101.