A cost-effectiveness analysis of provider interventions to improve health worker practice in providing treatment for uncomplicated malaria in Cameroon: A study protocol for a randomized controlled trial

Trials

Volumn 13, Issue , 2012, Pages

  Wiseman, Virginia ^a   Mangham, Lindsay J ^a   Cundill, Bonnie ^a   Achonduh, Olivia A ^b   Nji, Akindeh M ^b   Njei, Abanda N ^b   Chandler, Clare ^a   Mbacham, Wilfred F ^b  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY OF YAOUNDÉ I   (Cameroon)

Author keywords

Cost effectiveness; Malaria; Rapid diagnostics tests (RDTs)

Indexed keywords

ANTIMICROBIAL THERAPY; ARTICLE; CAREGIVER; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC TEST; DISEASE REGISTRY; ECONOMIC EVALUATION; FEVER; HEALTH CARE COST; HEALTH CARE DELIVERY; HEALTH CARE PERSONNEL; HEALTH CARE QUALITY; HEALTH SURVEY; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; HYPOTHESIS; INTERVIEW; MAJOR CLINICAL STUDY; MALARIA; MEDICAL PRACTICE; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; PROFESSIONAL COMPETENCE; PROFESSIONAL KNOWLEDGE; RANDOMIZED CONTROLLED TRIAL; STAFF TRAINING; ATTITUDE TO HEALTH; CAMEROON; CLINICAL PRACTICE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; COST BENEFIT ANALYSIS; ECONOMICS; EDUCATION; HEALTH PERSONNEL ATTITUDE; METHODOLOGY; MULTICENTER STUDY; PARAMEDICAL PERSONNEL; PREDICTIVE VALUE; STATISTICAL MODEL; TREATMENT OUTCOME;

ANTIMALARIAL AGENT;

ALLIED HEALTH PERSONNEL; ANTIMALARIALS; ATTITUDE OF HEALTH PERSONNEL; CAMEROON; COST-BENEFIT ANALYSIS; DIAGNOSTIC TESTS, ROUTINE; GUIDELINE ADHERENCE; HEALTH CARE COSTS; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; MALARIA; MODELS, ECONOMIC; PHYSICIAN'S PRACTICE PATTERNS; PRACTICE GUIDELINES AS TOPIC; PREDICTIVE VALUE OF TESTS; RESEARCH DESIGN; TREATMENT OUTCOME;

EID: 84855427659     PISSN: None     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/1745-6215-13-4     Document Type: Article

References (36)

1. Nshakira N, Kristensen M, Ssali F, Whyte SR. Appropriate treatment of malaria? Use of antimalarial drugs for children's fevers in district medical units, drug shops and homes in eastern Uganda. Trop Med Int Health 2002, 7:309-316. 10.1046/j.1365-3156.2002.00858.x, 11952946.
2. Williams H, Jones C. A critical review of behavioral issues related to malaria control in sub-Saharan Africa: what contributions have social scientists made?. Soc Sci & Med 2004, 59:501-523. 10.1016/j.socscimed.2003.11.010, 22198842.
3. Reyburn H, Mbakilwa H, Mwangi R, Obeni M, Raimos O. Rapid diagnostic tests compared with malaria microscopy for guiding outpatient treatment of febrile illness in Tanzania: randomized trial. BMJ 2007, 334:403. 10.1136/bmj.39073.496829.AE, 1804187, 17259188.
4. Zurovac D, Njogu J, Akhwale W, Hamer DH, Snow RW. Translation of artemether-lumefantrine treatment policy into paediatric clinical practice: an early experience from Kenya. Trop Med Int Health 2008, 13:99-107. 10.1111/j.1365-3156.2007.01980.x, 2592474, 18291008.
5. Zurovac D, Tibenderana JK, Nankabirwa J, Ssekitooleko J, Njogu JN, Rwakimari JB, Meek S, Talisuna A, Snow RW. Malaria case-management under artemether-lumefantrine treatment policy in Uganda. Malar J 2008, 7:181. 10.1186/1475-2875-7-181, 2556699, 18803833.
6. Rowe AK, Ponce de Leon GF, Mihigo J, Santelli CFS, Miller NP, Van-Dunem P. Quality of malaria case management at outpatient health facilities in Angola. Malar J 2009, 8:275. 10.1186/1475-2875-8-275, 2795764, 19954537.
7. Juma E, Zurovac D. Changes in health workers' malaria diagnosis and treatment practices in Kenya. Malar J 2011, 10:1. 10.1186/1475-2875-10-1, 3022768, 21214892.
8. Mangham L, Cundill B, Ezeoke O, Nwala E, Uzochukwu BSC, Wiseman V, Onwujekwe O. Treatment of uncomplicated malaria at public and private health facilities in South-Eastern Nigeria. Malar J 2011, 10:155. 10.1186/1475-2875-10-155, 3120734, 21651787.
9. Institut Nationale de la Statistique du Cameroun: Demographic Health Survey 2004. , http://www.statistics-Cameroon.org
10. Cameroon National Malaria Control Programme. Annual Report 2008. , http://www.minsante.gov.cm
11. World Health Organization Guidelines for the treatment of malaria 2010, World Health Organization, Geneva, second, World Health Organization.
12. Mangham LJ, Cundill B, Achonduh OA, Ambebila JN, Lele A, Metoh TN, Ndive SN, Ndong IC, Nguela RL, Nji AM, Orang-Ojong B, Pamen-Ngako J, Wiseman V, Mbacham WF. Malaria Prevalence and Treatment of Febrile Patients Attending Health Facilities in Cameroon. TMIH 2011, Nov 21, [Epub ahead of print].
13. Ministry of Public Health of the Republic of Cameroon: Scaling up malaria control for impact in Cameroon. Global Fund Proposal (R9_CCM_CMR_HTM_PF_4Aug09_ENG), Geneva. 2009, , http://portfolio.theglobalfund.org/en/Grant/List/CMR
14. Hopkins H, Asiimwe C, Bell D. Access to antimalarial therapy: accurate diagnosis is essential to achieving long term goals. BMJ 2009, 339:b2606. 10.1136/bmj.b2606, 19584113.
15. Amexo M, Tolhurst R, Barnish G, Bates I. Malaria misdiagnosis: effects on the poor and vulnerable. Lancet 2004, 364:1896-1898. 10.1016/S0140-6736(04)17446-1, 15555670.
16. Zikusooka CM, McIntyre D, Barnes KI. Should countries implementing an artemisinin-based combination malaria treatment policy also introduce rapid diagnostic tests?. Malar J 2008, 7:176. 10.1186/1475-2875-7-176, 2556342, 18793410.
17. World Health Organization Global Plan for Artemisinin Resistance Containment. 2011, Geneva: Global Malaria Programme, World Health Organization.
18. Bell D, Perkins MD. Making malaria testing relevant: Beyond test purchase. Trans R Soc Trop Med Hyg 2008, 102:1064-6. 10.1016/j.trstmh.2008.05.007, 18586290.
19. Williams HA, Causer L, Metta E, Malila A, O'Reilly T, Abdulla S, Kachur P, Bloland PB. Dispensary level pilot implementation of rapid diagnostic tests: an evaluation of RDT acceptance and usage by providers and patients - Tanzania, 2005. Malar J 2008, 7:239. 10.1186/1475-2875-7-239, 2613413, 19019233.
20. Chandler CIR, Whitty CJM, Ansah EK. How can malaria rapid diagnostic tests achieve their potential? A qualitative study of a trial at health facilities in Ghana. Malar J 2010, 9:95. 2859355, 20398262.
21. Kyabayinze DJ, Asiimwe C, Nakanjako D, Nabakooza J, Counihan H, Tibenderana JK. Use of RDTs to improve malaria diagnosis and fever case management at primary health facilities in Uganda. Malar J 2010, 9:200. 10.1186/1475-2875-9-200, 2914063, 20624312.
22. Mukanga D, Tibenderana JK, Kiguli J, Pariyo GW, Waiswa P, Bajunirwe F, Mutamba B, Counihan H, Ojiambo G, Kallander K. Community acceptability of use of rapid diagnostic tests for malaria by community health workers in Uganda. Malar J 2010, 9:203. 10.1186/1475-2875-9-203, 2914066, 20626863.
23. Onwujekwe O, Uzochukwu B, Dike N, Uguru Nm Nwobi E, Shu E. Malaria treatment perceptions, practices and influences on provider behaviour: comparing hospitals and non-hospitals in south-east Nigeria. Malar J 2009, 8:246. 10.1186/1475-2875-8-246, 2775747, 19863803.
24. World Health Organization Use of Rapid Diagnostic Tests 2006, Second, ISBN 9290612045, World Health Organization.
25. Chandler CIR, Mangham L, Njei AN, Achonduh O, Mbacham WF, Wiseman V. As a clinician, you are not managing lab results, you are managing the patient: how the enactment of malaria at health facilities in Cameroon compares with new WHO guidelines for the use of malaria tests. SS&M 2012, Unpublished data.
26. Smith LA, Jones C, Meek S, Wenster J. Review: Provider practice and user behaviour interventions to improve prompt and effective treatment of malaria: do we know what works?. Am J Trop Med Hy 2009, 80(3):326-335.
27. Goodman CA, Brieger W, Unwin A, Mills A, Meek S, Greer G. Medicine Sellers and Malaria Treatment in Sub-Saharan Africa: What Do They Do and How Can Their Practice Be Improved?. Am J Trop Med Hy 2007, 77(Suppl 6):203-218.
28. Brieger W, Unwin A, Meek S, Greer G. Interventions to improve the role of medicine sellers in malaria case management for children in Africa 2005, London UK and Arlington, Va, USA: The Malaria Consortium and BASICS for the United States Agency for International Development; prepared for the Roll Back Malaria's sub-group for Communication and Training and Malaria Case Management Working Group., http://www.rollbackmalaria.org/partnership/wg/wg_management/docs/medsellersRBMmtgsubcommitteereport.pdf
29. Atangana J, Bigoga JD, Patchoke S, Ndjemai HMN, Tabue NR, Nem TE, Fonjo E. Anopheline fauna and malaria transmission in four ecologically distinct zones in Cameroon. Acta Trop 2010, 115(1-2):131-136. 10.1016/j.actatropica.2010.02.014, 20206111.
30. Cameroon National Malaria Control Program Plan Strategique National de lute contre le Paludisme au Cameroun 2011, Cameroon National Malaria Control Program., http://www.afro.who.int/en/downloads/cat_view/1501-english/969-countries/979-cameroon.html
31. World Health Organisation, FIND, CDC, & TDR Malaria rapid diagnostic test performance. Results of WHO product testing of malaria RDTs: Round 2 (2009) 2010, World Health Organisation, FIND, CDC, & TDR., http://www.wpro.who.int/sites/rdt/who_rdt_evaluation/call_for_testing_round2.htm
32. Drummond MF, Sculpher MJ, Torrance GW, O'Brien BJ, Stoddart GL. Methods for the economic evaluation of health care programmes 2005, Oxford: Oxford Medical Publications, 3.
33. Hayes RJ, Moulton LH. Cluster Randomised Trials 2009, Chapman & Hall/CRC.
34. Sismanidis C, Moulton LH, Ayles H, Fielding K, Schaap A, Beyers N, Bond G, Godfrey-Faussett P, Hayes R. Restricted randomisation of ZAMSTAR: a 2 × 2 factorial cluster randomized trial. Clin Trials 2008, 5:316-3278. 10.1177/1740774508094747, 18697846.
35. Moulton LH. Covariate-based constrained randomization of group-randomized trials. Clin Trials 2004, 1:297-305. 10.1191/1740774504cn024oa, 16279255.
36. Cheung YB, Jeffries D, Thomson A, Milligan P. A simple approach to test for the interaction between intervention and an individual-level variable in community randomized trials. TMIH 2008, 19(2):247-255.