Vitiligo treatment with monochromatic excimer light and tacrolimus: Results of an open randomized controlled study

Photomedicine and Laser Surgery

Volumn 30, Issue 1, 2012, Pages 26-30

  Nisticò, Steven ^a   Chiricozzi, Andrea ^a   Saraceno, Rosita ^a   Schipani, Caterina ^a   Chimenti, Sergio ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL RESPONSE; COMBINATION TREATMENTS; COMBINED TREATMENT; EXCIMER LIGHT; GROUP III; IMMUNOMODULATORS; LONG LASTING; MONO-THERAPY; NARROW BANDS; NEW STRATEGY; PHOTOTHERAPY; PROSPECTIVE STUDY; TACROLIMUS; ULTRAVIOLET B; VITAMIN-E;

PATIENT MONITORING;

PATIENT TREATMENT;

IMMUNOSUPPRESSIVE AGENT; OINTMENT BASE; TACROLIMUS;

ADOLESCENT; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EXCIMER LASER; FEMALE; HUMAN; LOW LEVEL LASER THERAPY; MALE; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; RANDOMIZED CONTROLLED TRIAL; TOPICAL DRUG ADMINISTRATION; VITILIGO;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; COMBINED MODALITY THERAPY; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LASER THERAPY, LOW-LEVEL; LASERS, EXCIMER; MALE; MIDDLE AGED; OINTMENT BASES; TACROLIMUS; VITILIGO; YOUNG ADULT;

EID: 84855419731     PISSN: 15495418     EISSN: None     Source Type: Journal    
DOI: 10.1089/pho.2011.3029     Document Type: Article

References (21)

1. Naldi, L., Colombo, P., Placchesi, E.B., et al. (2004). Study design and preliminary results from the pilot phase of the PraKtis study: self reported diagnoses of selected skin diseases in a representative sample of the Italian population. Dermatology 208, 38-42. (Pubitemid 38142332)
2. Howitz, J., Brodthagen, H., Schwartz, M., and Thomsen, K. (1977). Prevalence of vitiligo. Epidemiological survey on the Isle of Bornholm, Denmark. Arch. Dermatol. 113, 47-52. (Pubitemid 8020128)
3. Taïeb, A., Picardo, M., and VETF Members. (2007). The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force. Pigment. Cell Res. 20, 27-35. (Pubitemid 46090162)
4. Gawkrodger, D.J., Ormerod, A.D., Shaw, L., et al. (2008). Guideline for the diagnosis and management of vitiligo. Br. J. Dermatol. 159, 1051-1076.
5. Mofty, M.E., Zaher, H., Esmat, S., et al. (2001). PUVA and PUVB in vitiligo-are they equally effective? Photodermatol. Photoimmunol. Photomed. 17, 159-163. (Pubitemid 32677595)
6. Scherschun, L., Kim, J.J., and Lim, H.W. (2001). Narrowband ultraviolet B is a useful and well tolerated treatment for vitiligo. J. Am. Acad. Dermatol. 44, 999-1003. (Pubitemid 32493452)
7. Taneja, A. (2002). Treatment of vitiligo. J. Dermatolog. Treat. 13, 19-25. (Pubitemid 34163695)
8. Leone, G., Iacovelli, P., Parovidolin, A., and Picardo, M. (2003). Monochromatic excimer light 308nm in the treatment of vitiligo: a pilot study. J. Eur. Acad. Dermatol. Venereol. 17, 531-537. (Pubitemid 37138890)
9. Tanghetti, E.A. (2003). Tacrolimus ointment 0.1% produces repigmentation in patients with vitiligo: results of a prospective patient series. Cutis 71, 158-162. (Pubitemid 38010838)
10. Grimes, P.E., Soriano, T., and Dytoc, M.T. (2002). Topical tacrolimus for repigmentation of vitiligo. J. Am. Acad. Dermatol. 47, 789-791. (Pubitemid 35239348)
11. Berti, S., Buggiani, G., and Lotti, T. (2009). Use of tacrolimus ointment in vitiligo alone or in combination therapy. Skin Therapy Lett. 14, 5-7.
12. Kawalek, A.Z., Spencer, J.M., and Phelps, R.G. (2004). Combined excimer laser and topical tacrolimus for the treatment of vitiligo: a pilot study. Dermatol. Surg. 30, 130-135. (Pubitemid 38313998)
13. Castanedo-Cazares, J.P., Lepe, V., and Moncada, B. (2003). Repigmentation of chronic vitiligo lesions by following tacrolimus plus ultraviolet-B-narrow band. Photodermatol. Photoimmunol. Photomed. 19, 35-36. (Pubitemid 36621677)
14. Fai, D., Cassano, N., and Vena, G.A. (2007). Narrow-band UVB phototherapy combined with tacrolimus ointment in vitiligo: a review of 110 patients. J. Eur. Acad. Dermatol. Venereol. 21, 916-920. (Pubitemid 47103721)
15. Dell'Anna, M.L., Mastrofrancesco, A., Sala, R., et al. (2007). Antioxidants and narrow band-UVB in the treatment of vitiligo: a double-blind placebo controlled trial. Clin. Exp. Dermatol. 32, 631-636. (Pubitemid 47609756)
16. Zhang, X.Y., He, Y.L., Dong, J., Xu, J.Z., and Wang, J. (2010). Clinical efficacy of a 308nm excimer laser in the treatment of vitiligo. Photodermatol. Photoimmunol. Photomed. 26, 138-142.
17. Le Duff, F., Fontas, E., Giacchero, D., et al. (2010). 308-nm excimer lamp vs. 308-nm excimer laser for treating vitiligo: a randomized study. Br. J. Dermatol. 163, 188-192.
18. Saraceno, R., Nisticò, S.P., Capriotti, E., and Chimenti, S. (2009). Monochromatic excimer light 308nm in monotherapy and combined with topical khellin 4% in the treatment of vitiligo: a controlled study. Dermatol. Ther. 22, 391-394.
19. Passeron, T., Ostovari, N., Zakaria, W., et al. (2004). Topical tacrolimus and the 308-nm excimer laser: a synergistic combination for the treatment of vitiligo. Arch. Dermatol. 140, 1065-1069. (Pubitemid 39223113)
20. Yarosh, D.B., Pena, A.V., Nay, S.L., Canning, M.T., and Brown, D.A. (2005). Calcineurin inhibitors decrease DNA repair and apoptosis in human keratinocytes following ultraviolet B irradiation. J. Invest. Dermatol. 125, 1020-1025.
21. Tran, C., Lubbe, J., Sorg, O., et al. (2005). Topical calcineurin inhibitors decrease the production of UVB-induced thymine dimers from hair less mouse epidermis. Dermatology 211, 341-347. (Pubitemid 41642109)