Altered CD4 + T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals

Journal of Clinical Investigation

Volumn 122, Issue 1, 2012, Pages 62-69

  Mavigner, Maud ^a   Cazabat, Michelle ^a,b   Dubois, Martine ^a,b   L'Faqihi, Fatima Ezzahra ^a   Requena, Mary ^a   Pasquier, Christophe ^a,b   Klopp, Pascale ^c   Amar, Jacques ^c,d   Alric, Laurent ^b,e   Barange, Karl ^b   Vinel, Jean Pierre ^b   Marchou, Bruno ^b   Massip, Patrice ^b   Izopet, Jacques ^a,b   Delobel, Pierre ^a,b  

^a INSERM   (France)

^b CHU PURPAN   (France)

^c University Hospital of Toulouse   (France)

^d CHU RANGUEIL   (France)

^e CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4BETA7 INTEGRIN; CHEMOKINE RECEPTOR CCR9; INTEGRIN; UNCLASSIFIED DRUG;

ARTICLE; CD4+ T LYMPHOCYTE; CELL HOMING; CELL MIGRATION; CELL POPULATION; CIRCULATION; CLINICAL ARTICLE; CONTROLLED STUDY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME; MUCOSAL IMMUNITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMALL INTESTINE MUCOSA; STOMACH MUCOSA LESION; T LYMPHOCYTE ACTIVATION; TH17 CELL;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; CHEMOKINES, CC; HIV INFECTIONS; HIV-1; HUMANS; IMMUNITY, MUCOSAL; INTEGRIN BETA CHAINS; INTESTINAL MUCOSA; INTESTINE, SMALL; RECEPTORS, CCR; RNA, MESSENGER; T-LYMPHOCYTE SUBSETS; TH17 CELLS;

EID: 84855417479     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI59011     Document Type: Article

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