Using imaging to identify psychogenic parkinsonism before deep brain stimulation surgery: Report of 2 cases

Journal of Neurosurgery

Volumn 116, Issue 1, 2012, Pages 114-118

  Pourfar, Michael H ^a   Tang, Chris C ^b   Mogilner, Alon Y ^a   Dhawan, Vijay ^a,b   Eidelberg, David ^a,b  

^a NORTH SHORE UNIVERSITY HOSPITAL   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

Deep brain stimulation; Functional neurosurgery; Parkinson disease; PET; Psychogenic parkinsonism

Indexed keywords

6 FLUORODOPA F 18; CARBIDOPA PLUS LEVODOPA; ENTACAPONE; PRAMIPEXOLE;

ADULT; ARTICLE; BRAIN ABSCESS; BRAIN DEPTH STIMULATION; CASE REPORT; CAUDATE NUCLEUS; CEREBELLUM; CLINICAL DECISION MAKING; CLINICAL FEATURE; DIFFERENTIAL DIAGNOSIS; DIPLOPIA; DIZZINESS; DYSKINESIA; DYSPHAGIA; FATIGUE; FEMALE; GAIT DISORDER; HAND TREMOR; HUMAN; IDIOPATHIC DISEASE; INCONTINENCE; MALE; MEMORY DISORDER; MOTOR CORTEX; MOTOR DYSFUNCTION; MUSCLE SPASM; MUSCLE STIFFNESS; NEUROSURGERY; NIGHT SWEAT; PARESTHESIA; PARKINSON DISEASE; PARKINSONISM; PHYSICAL EXAMINATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PSYCHOGENIC PARKINSONISM; PUTAMEN; RIGIDITY; STUTTERING; SURGICAL RISK; URINARY DYSFUNCTION;

ADULT; BRAIN; DEEP BRAIN STIMULATION; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; MIDDLE AGED; PARKINSON DISEASE; PARKINSONIAN DISORDERS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84855406377     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2011.10.JNS11554     Document Type: Article

References (22)

1. Benaderette S, Zanotti Fregonara P, Apartis E, Nguyen C, Trocello JM, Remy P, et al: Psychogenic parkinsonism: a combination of clinical, electrophysiological, and [(123)I]-FP-CIT SPECT scan explorations improves diagnostic accuracy. Mov Disord 21:310-317, 2006
2. Dhawan V, Eidelberg D: PET imaging in Parkinson's disease and other neurodegenerative disorders, in Gilman S (ed): Neurobiology of Disease. San Diego: Elsevier Academic Press, 2007, pp 821-828
3. Dhawan V, Ma Y, Pillai V, Spetsieris P, Chaly T, Belakhlef A, et al: Comparative analysis of striatal FDOPA uptake in Parkinson's disease: ratio method versus graphical approach. J Nucl Med 43:1324-1330, 2002
4. Eckert T, Barnes A, Dhawan V, Frucht S, Gordon MF, Feigin AS, et al: FDG PET in the differential diagnosis of parkinsonian disorders. Neuroimage 26:912-921, 2005 (Pubitemid 40825033)
5. Eckert T, Feigin A, Lewis DE, Dhawan V, Frucht S, Eidelberg D: Regional metabolic changes in parkinsonian patients with normal dopaminergic imaging. Mov Disord 22:167-173, 2007 (Pubitemid 46374756)
6. Eckert T, Tang C, Ma Y, Brown N, Lin T, Frucht S, et al: Abnormal metabolic networks in atypical parkinsonism. Mov Disord 23:727-733, 2008
7. Eidelberg D: Metabolic brain networks in neurodegenerative disorders: a functional imaging approach. Trends Neurosci 32:548-557, 2009
8. Factor SA, Podskalny GD, Molho ES: Psychogenic movement disorders: frequency, clinical profile, and characteristics. J Neurol Neurosurg Psychiatry 59:406-412, 1995
9. Freed CR, Greene PE, Breeze RE, Tsai WY, DuMouchel W, Kao R, et al: Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med 344:710-719, 2001 (Pubitemid 32204988)
10. Gaig C, Martí MJ, Tolosa E, Valldeoriola F, Paredes P, Lomeña FJ, et al: 123I-Ioflupane SPECT in the diagnosis of suspected psychogenic Parkinsonism. Mov Disord 21:1994-1998, 2006 (Pubitemid 44848954)
11. Lang AE, Koller WC, Fahn S: Psychogenic parkinsonism. Arch Neurol 52:802-810, 1995
12. Ma Y, Tang C, Chaly T, Greene P, Breeze R, Fahn S, et al: Dopamine cell implantation in Parkinson's disease: long-term clinical and (18)F-FDOPA PET outcomes. J Nucl Med 51: 7-15, 2010
13. Ma Y, Tang C, Spetsieris PG, Dhawan V, Eidelberg D: Abnormal metabolic network activity in Parkinson's disease: test-retest reproducibility. J Cereb Blood Flow Metab 27:597-605, 2007
14. Marek K, Jennings D, Seibyl J: Long-term follow-up of patients with scans without evidence of dopaminergic deficit (SWEDD) in the ELLDOPA study. Neurology 64 (1 Suppl): A274, 2005
15. Marek K, Seibyl J: Beta-CIT scans without evidence of dopaminergic deficit (SWEDD) in the ELLDOPA-CIT and CALM-CIT study: long-term imaging assessment. Neurology 60 (1 Suppl):A293, 2003
16. Marshall VL, Patterson J, Hadley DM, Grosset KA, Grosset DG: Two-year follow-up in 150 consecutive cases with normal dopamine transporter imaging. Nucl Med Commun 27:933-937, 2006 (Pubitemid 44706887)
17. Marshall VL, Reininger CB, Marquardt M, Patterson J, Hadley DM, Oertel WH, et al: Parkinson's disease is overdiagnosed clinically at baseline in diagnostically uncertain cases: a 3-year European multicenter study with repeat [123I]FPCIT SPECT. Mov Disord 24:500-508, 2009
18. Piccini P, Brooks DJ: New developments of brain imaging for Parkinson's disease and related disorders. Mov Disord 21: 2035-2041, 2006 (Pubitemid 46140409)
19. Poston KL, Tang C, Eckert T, Ma Y, Frucht S, Eidelberg D: Longitudinal changes in regional metabolism and network activity in multiple system atrophy. Neurology 72 (Suppl 3): A67, 2009
20. Spetsieris PG, Ma Y, Dhawan V, Eidelberg D: Differential diagnosis of parkinsonian syndromes using PCA-based functional imaging features. Neuroimage 45:1241-1252, 2009
21. Tang CC, Poston KL, Eckert T, Feigin A, Frucht S, Gudesblatt M, et al: Differential diagnosis of parkinsonism: a metabolic imaging study using pattern analysis. Lancet Neurol 9:149-158, 2010
22. Whone AL, Watts RL, Stoessl AJ, Davis M, Reske S, Nahmias C, et al: Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study. Ann Neurol 54:93-101, 2003 (Pubitemid 36764985)