Amylin is a novel neuropeptide with potential maternal functions in the rat

FASEB Journal

Volumn 26, Issue 1, 2012, Pages 272-281

  Szabó, Éva Rebeka ^a   Cservenák, Melinda ^a   Dobolyi, Arpád ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Hypothalamus; Peptide expression; Postpartum mother; Preoptic area

Indexed keywords

AMYLIN; AMYLIN RECEPTOR; MESSENGER RNA; SEX HORMONE;

ADAPTIVE BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIRTH; CONTROLLED STUDY; FEMALE; HORMONE BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LACTATION; MATERNAL BEHAVIOR; NERVE PROJECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; NULLIPARA; OVARIECTOMY; PREOPTIC AREA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PUP (RODENT); RAT; SENSITIZATION; WISTAR RAT;

ANIMALS; ANIMALS, SUCKLING; BEHAVIOR, ANIMAL; FEMALE; ISLET AMYLOID POLYPEPTIDE; MATERNAL BEHAVIOR; MATERNAL DEPRIVATION; NEURAL PATHWAYS; NEURONS; OVARIECTOMY; PERIPARTUM PERIOD; POSTPARTUM PERIOD; PREGNANCY; PREOPTIC AREA; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; RNA, MESSENGER;

RATTUS;

EID: 84855399713     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-191841     Document Type: Article

References (52)

1. Wimalawansa, S. J. (1997) Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily. Crit. Rev. Neurobiol. 11, 167-239
2. Leffert, J. D., Newgard, C. B., Okamoto, H., Milburn, J. L., and Luskey, K. L. (1989) Rat amylin: cloning and tissue-specific expression in pancreatic islets. Proc. Natl. Acad. Sci. U. S. A. 86, 3127-3130 (Pubitemid 19129571)
3. Hay, D. L., Christopoulos, G., Christopoulos, A., and Sexton, P. M. (2004) Amylin receptors: molecular composition and pharmacology. Biochem. Soc. Trans. 32, 865-867 (Pubitemid 39524399)
4. Poyner, D. R., Sexton, P. M., Marshall, I., Smith, D. M., Quirion, R., Born, W., Muff, R., Fischer, J. A., and Foord, S. M. (2002) International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol. Rev. 54, 233-246 (Pubitemid 34575714)
5. Young, A. (2005) Tissue expression and secretion of amylin. Adv. Pharmacol. 52, 19-45
6. Lutz, T. A. (2006) Amylinergic control of food intake. Physiol. Behav. 89, 465-471
7. Potes, C. S., and Lutz, T. A. (2010) Brainstem mechanisms of amylin-induced anorexia. Physiol. Behav. 100, 511-518
8. Mulder, H., Leckstrom, A., Uddman, R., Ekblad, E., Westermark, P., and Sundler, F. (1995) Islet amyloid polypeptide (amylin) is expressed in sensory neurons. J. Neurosci. 15, 7625-7632
9. Gebre-Medhin, S., Mulder, H., Zhang, Y., Sundler, F., and Betsholtz, C. (1998) Reduced nociceptive behavior in islet amyloid polypeptide (amylin) knockout mice. Brain Res. Mol. Brain Res. 63, 180-183 (Pubitemid 28559099)
10. Dobolyi, A. (2009) Central amylin expression and its induction in rat dams. J. Neurochem. 111, 1490-1500
11. Numan, M., and Woodside, B. (2010) Maternity: neural mechanisms, motivational processes, and physiological adaptations. Behav. Neurosci. 124, 715-741
12. Gray, P., and Brooks, P. J. (1984) Effect of lesion location within the medial preoptic-anterior hypothalamic continuum on maternal and male sexual behaviors in female rats. Behav. Neurosci. 98, 703-711 (Pubitemid 14037796)
13. Numan, M. (1986) The role of the medial preoptic area in the regulation of maternal behavior in the rat. Ann. N. Y. Acad. Sci. 474, 226-233
14. Lonstein, J. S., Simmons, D. A., Swann, J. M., and Stern, J. M. (1998) Forebrain expression of c-fos due to active maternal behaviour in lactating rats. Neuroscience 82, 267-281
15. Stack, E. C., and Numan, M. (2000) The temporal course of expression of c-Fos and Fos B within the medial preoptic area and other brain regions of postpartum female rats during prolonged mother-young interactions. Behav. Neurosci. 114, 609-622 (Pubitemid 30490907)
16. Numan, M., and Numan, M. J. (1997) Projection sites of medial preoptic area and ventral bed nucleus of the stria terminalis neurons that express Fos during maternal behavior in female rats. J. Neuroendocrinol. 9, 369-384 (Pubitemid 27212047)
17. Rosenblatt, J. S. (1967) Nonhormonal basis of maternal behavior in the rat. Science 156, 1512-1514
18. Fleming, A. S., and Rosenblatt, J. S. (1974) Maternal behavior in the virgin and lactating rat. J. Comp. Physiol. Psychol. 86, 957-972
19. Lamming, G. E., ed (1994) Marshall's Physiology of Reproduction, Vol. 3, Chapman & Hall, London
20. Wayneforth, H., and Flecknell, P. (1992) Experimental and Surgical Techniques in the Rat, Academic Press, London
21. Dobolyi, A., and Palkovits, M. (2008) Expression of latent transforming growth factor beta binding proteins in the rat brain. J. Comp. Neurol. 507, 1393-1408 (Pubitemid 351413578)
22. Dobolyi, A., Ueda, H., Uchida, H., Palkovits, M., and Usdin, T. B. (2002) Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception. Proc. Natl. Acad. Sci. U. S. A. 99, 1651-1656 (Pubitemid 34136547)
23. Dobolyi, A., Irwin, S., Makara, G., Usdin, T. B., and Palkovits, M. (2005) Calcitonin gene-related peptide-containing pathways in the rat forebrain. J. Comp. Neurol. 489, 92-119 (Pubitemid 40934675)
24. Herdegen, T., and Leah, J. D. (1998) Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res. Brain Res. Rev. 28, 370-490 (Pubitemid 29012678)
25. Cservenak, M., Bodnar, I., Usdin, T. B., Palkovits, M., Nagy, G. M., and Dobolyi, A. (2010) Tuberoinfundibular peptide of 39 residues is activated during lactation and participates in the suckling-induced prolactin release in rat. Endocrinology 151, 5830-5840
26. Coolen, L. M., Peters, H. J., and Veening, J. G. (1998) Anatomical interrelationships of the medial preoptic area and other brain regions activated following male sexual behavior: a combined fos and tract-tracing study. J. Comp. Neurol. 397, 421-435 (Pubitemid 28307342)
27. Dobolyi, A. (2011) Novel potential regulators of maternal adaptations during lactation: tuberoinfundibular peptide 39 and amylin. [E-pub ahead of print] J. Neuroendocrinol. doi: 10.1111/j.1365-2826.2011.02127.x
28. Simerly, R. B., and Swanson, L. W. (1986) The organization of neural inputs to the medial preoptic nucleus of the rat. J. Comp. Neurol. 246, 312-342 (Pubitemid 16079501)
29. Li, C., Chen, P., and Smith, M. S. (1999) Neural populations in the rat forebrain and brainstem activated by the suckling stimulus as demonstrated by cFos expression. Neuroscience 94, 117-129 (Pubitemid 29457602)
30. Lin, S. H., Miyata, S., Matsunaga, W., Kawarabayashi, T., Nakashima, T., and Kiyohara, T. (1998) Metabolic mapping of the brain in pregnant, parturient and lactating rats using fos immunohistochemistry. Brain Res. 787, 226-236 (Pubitemid 28197909)
31. Simerly, R. B., and Swanson, L. W. (1988) Projections of the medial preoptic nucleus: a Phaseolus vulgaris leucoagglutinin anterograde tract-tracing study in the rat. J. Comp. Neurol. 270, 209-242
32. Sexton, P. M., Paxinos, G., Kenney, M. A., Wookey, P. J., and Beaumont, K. (1994) In vitro autoradiographic localization of amylin binding sites in rat brain. Neuroscience 62, 553-567 (Pubitemid 24306678)
33. Sheward, W. J., Lutz, E. M., and Harmar, A. J. (1994) The expression of the calcitonin receptor gene in the brain and pituitary gland of the rat. Neurosci. Lett. 181, 31-34 (Pubitemid 24343398)
34. Becskei, C., Riediger, T., Zund, D., Wookey, P., and Lutz, T. A. (2004) Immunohistochemical mapping of calcitonin receptors in the adult rat brain. Brain Res. 1030, 221-233
35. Numan, M., and Insel, T. R. (2003) The Neurobiology of Parental Behavior, Springer, New York
36. Bosch, O. J., and Neumann, I. D. (2008) Brain vasopressin is an important regulator of maternal behavior independent of dams'trait anxiety. Proc. Natl. Acad. Sci. U. S. A. 105, 17139-17144
37. Leng, G., Meddle, S. L., and Douglas, A. J. (2008) Oxytocin and the maternal brain. Curr. Opin. Pharmacol. 8, 731-734
38. Kinsley, C. H., and Lambert, K. G. (2008) Reproductioninduced neuroplasticity: natural behavioural and neuronal alterations associated with the production and care of offspring. J. Neuroendocrinol. 20, 515-525 (Pubitemid 351437037)
39. Bosch, O. J., Pfortsch, J., Beiderbeck, D. I., Landgraf, R., and Neumann, I. D. (2010) Maternal behaviour is associated with vasopressin release in the medial preoptic area and bed nucleus of the stria terminalis in the rat. J. Neuroendocrinol. 22, 420-429
40. Tohyama, M., and Takatsuji, K. (1998) Atlas of Neuroactive Substances and their Receptors in the Rat, Oxford University Press, New York
41. Augustine, R. A., Ladyman, S. R., and Grattan, D. R. (2008) From feeding one to feeding many: hormone-induced changes in bodyweight homeostasis during pregnancy. J. Physiol. 586, 387-397
42. Smith, M. S., and Grove, K. L. (2002) Integration of the regulation of reproductive function and energy balance: lactation as a model. Front. Neuroendocrinol. 23, 225-256 (Pubitemid 34856514)
43. Woodside, B. (2007) Prolactin and the hyperphagia of lactation. Physiol. Behav. 91, 375-382
44. Rushing, P. A., Hagan, M. M., Seeley, R. J., Lutz, T. A., D'Alessio, D. A., Air, E. L., and Woods, S. C. (2001) Inhibition of central amylin signaling increases food intake and body adiposity in rats. Endocrinology 142, 5035
45. Lutz, T. A., Mollet, A., Rushing, P. A., Riediger, T., and Scharrer, E. (2001) The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats. Int. J. Obes. Relat. Metab. Disord. 25, 1005-1011 (Pubitemid 32566055)
46. Numan, M., and Sheehan, T. P. (1997) Neuroanatomical circuitry for mammalian maternal behavior. Ann. N. Y. Acad. Sci. 807, 101-125 (Pubitemid 27135488)
47. Knobil, E., and Neill, J. D. (2006) Knobil and Neill's Physiology of Reproduction, Vol. 2, Academic Press, San Diego, CA, USA
48. Freeman, M. E., Kanyicska, B., Lerant, A., and Nagy, G. (2000) Prolactin: structure, function, and regulation of secretion. Physiol. Rev. 80, 1523-1631
49. Burbach, J. P. H., Young, L. J., and Russell, J. A. (2006) Oxytocin: synthesis, secretion, and reproductive functions. In Knobil and Neill's Physiology of Reproduction (Knobil, E., and Neill, J. D., ed) pp. 3055-3128, Academic Press, Oxford, UK
50. McNeilly, A. S. (2006) Suckling and the control of gonadotropin secretion. In Knobil and Neill's Physiology of Reproduction (Neill, J. D., ed), pp. 2511-2552, Academic, Oxford
51. Carter, C. S., Altemus, M., and Chrousos, G. P. (2001) Neuroendocrine and emotional changes in the post-partum period. Prog. Brain Res. 133, 241-249
52. Mallikarjun, P. K., and Oyebode, F. (2005) Prevention of postnatal depression. J. R. Soc. Health 125, 221-226 (Pubitemid 43055178)