G protein-coupled receptors: Case builds for TGR5 as metabolic syndrome target

Nature Reviews Drug Discovery

Volumn 11, Issue 1, 2012, Pages 22-23

  Legg, Katrin ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BILE ACID; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INT 777; INTERLEUKIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEIN TGR5; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ATHEROSCLEROSIS; CYTOKINE PRODUCTION; DRUG RESPONSE; DRUG TARGETING; ENERGY EXPENDITURE; INFLAMMATION; INSULIN RESISTANCE; MACROPHAGE; METABOLIC SYNDROME X; NONHUMAN; NOTE; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 84855389489     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd3638     Document Type: Note

References (1)

1. Pols, T. W. H. et al. TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading. Cell Metab.14, 747-757 (2011)