Molecular adsorbent recirculating system as artificial support therapy for liver failure: A meta-analysis

ASAIO Journal

Volumn 58, Issue 1, 2012, Pages 51-59

  Vaid, Arjun ^a,b   Chweich, Haval ^a,b   Balk, Ethan M ^b,c   Jaber, Bertrand L ^a,b  

^a ST ELIZABETH'S MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTIFICIAL LIVER; BENEFICIAL EFFECTS; CONTROLLED TRIAL; HEPATIC ENCEPHALOPATHIES; LIVER FAILURE; MEDICAL THERAPY; MEDLINE; META-ANALYSIS; ODDS RATIOS; PROMISING THERAPY; RANDOMIZED CONTROLLED TRIAL; RECIRCULATING SYSTEM; SCIENTIFIC MEETINGS; SMALL SAMPLE SIZE; SUPPORT SYSTEMS;

ARTIFICIAL ORGANS; NEURODEGENERATIVE DISEASES;

PATIENT TREATMENT;

BILIRUBIN;

ACUTE LIVER FAILURE; ADSORPTION; ADULT; ARTICLE; BLOOD; CHRONIC DISEASE; CLINICAL TRIAL (TOPIC); DETOXIFICATION; FEMALE; HUMAN; LIVER; LIVER FAILURE; LIVER TRANSPLANTATION; MALE; META ANALYSIS; METHODOLOGY; MIDDLE AGED; MORTALITY; PATHOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC);

ADSORPTION; ADULT; BILIRUBIN; CHRONIC DISEASE; CLINICAL TRIALS AS TOPIC; FEMALE; HUMANS; LIVER; LIVER FAILURE; LIVER FAILURE, ACUTE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SORPTION DETOXIFICATION;

EID: 84855387659     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/MAT.0b013e31823fd077     Document Type: Article

References (38)

1. Polson J, Lee WM; American Association for the Study of Liver Disease: AASLD position paper: The management of acute liver failure. Hepatology 41: 1179-1197, 2005. (Pubitemid 40593928)
2. Ostapowicz G, Fontana RJ, Schiødt FV, et al; U.S. Acute Liver Failure Study Group: Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 137: 947-954, 2002. (Pubitemid 35440240)
3. K eeffe EB: Liver transplantation: Current status and novel approaches to liver replacement. Gastroenterology 120: 749-762, 2001.
4. The U.S. Organ Procurement and Transplantation Network/The Scientific Registry of Transplant Recipients Data. Available at http://optn.transplant. hrsa.gov/ar2009/901a-wait-time-li.htm. Accessed May 4 2009
5. Heron M, Hoyert DL, Murphy SL, Xu J, Kochanek KD, Tejada-Vera B: Deaths: Final data for 2006. Natl Vital Stat Rep 57: 1-134, 2009.
6. Stockmann HB, Hiemstra CA, Marquet RL, IJzermans JN: Extracorporeal perfusion for the treatment of acute liver failure. Ann Surg 231: 460-470, 2000. (Pubitemid 30185851)
7. Montejo González JC, Catalán González M, Meneu Diaz JC, Moreno Elola-Olaso A, De la Cruz J, Moreno González E: Artificial liver support system in acute liver failure patients waiting liver transplantation. Hepatogastroenterology 56: 456-461, 2009.
8. Bañares R, Nevens F, Larsen FS, Jalan R, Albillos A, Dollinger M; Relief Study Group Extracorporeal liver support with the Molecular Adsorbent Recirculating System (MARS) in patients with acute-on-chronic liver failure (aoclf). The RELIEF trial in The International Liver Congress 2010 (EASL) Vienna, Austria, 2010.
9. Lee KH, Wendon J, Lee M, Da Costa M, Lim SG, Tan KC: Predicting the decrease of conjugated bilirubin with extracorporeal albumin dialysis MARS using the predialysis molar ratio of conjugated bilirubin to albumin. Liver Transpl 8: 591-593, 2002. (Pubitemid 34752705)
10. Steiner C, Sen S, Stange J, Williams R, Jalan R: Binding of bilirubin and bromosulphthalein to albumin: Implications for understanding the pathophysiology of liver failure and its management. Liver Transpl 10: 1531-1538, 2004. (Pubitemid 40028387)
11. Blei AT, Córdoba J; Practice Parameters Committee of the American College of Gastroenterology: Hepatic Encephalopathy. Am J Gastroenterol 96: 1968-1976, 2001.
12. Conn HO: Trailmaking and number-connection tests in the assessment of mental state in portal systemic encephalopathy. Am J Dig Dis 22: 541-550, 1977. (Pubitemid 8116254)
13. Ferenci P, Lockwood A, Mullen K, Tarter R, Weissenborn K, Blei AT: Hepatic encephalopathy-definition, nomenclature, diagnosis, and quantification: Final report of the working party at the 11th World Congresses of Gastroenterology, Vienna, 1998. Hepatology 35: 716-721, 2002. (Pubitemid 34183979)
14. Sen S, Davies NA, Mookerjee RP, et al: Pathophysiological effects of albumin dialysis in acute-on-chronic liver failure: A randomized controlled study. Liver Transpl 10: 1109-1119, 2004. (Pubitemid 39248408)
15. Jadad AR, Moore RA, Carroll D, et al: Assessing the quality of reports of randomized clinical trials: Is blinding necessary? Control Clin Trials 17 1-12 1996 (Pubitemid 26120810)
16. Seabra VF, Alobaidi S, Balk EM, Poon AH, Jaber BL: Off-pump coronary artery bypass surgery and acute kidney injury: A meta- analysis of randomized controlled trials. Clin J Am Soc Nephrol 5: 1734-1744, 2010.
17. Yusuf S, Peto R, Lewis J, Collins R, Sleight P: Beta blockade during and after myocardial infarction: An overview of the randomized trials. Prog Cardiovasc Dis 27: 335-371, 1985. (Pubitemid 15107153)
18. Rücker G, Schwarzer G, Carpenter J, Olkin I: Why add anything to nothing? The arcsine difference as a measure of treatment effect in meta-analysis with zero cells. Stat Med 28: 721-738, 2009.
19. DerSimonian R, Laird N: Meta-analysis in clinical trials. Control Clin Trials 7: 177-188, 1986. (Pubitemid 17189972)
20. Hozo SP, Djulbegovic B, Hozo I: Estimating the mean and variance from the median, range, and the size of a sample. BMC Med Res Methodol 5: 13, 2005.
21. Wallace BC, Schmid CH, Lau J, Trikalinos TA: Meta-Analyst: Software for meta-analysis of binary, continuous and diagnostic data. BMC Med Res Methodol 9: 80, 2009.
22. Ross JH, Michael JB, Jonathan JD, Roger MH, Douglas GA, Jonathan ACS: Metan: Fixed- and random-effects meta-analysis. Stata Journal 8: 28, 2008.
23. Hessel FP, Bramlage P, Wasem J, Mitzner SR: Cost-effectiveness of the artificial liver support system MARS in patients with acuteon- chronic liver failure. Eur J Gastroenterol Hepatol 22: 213- 220, 2010.
24. Mitzner SR, Stange J, Klammt S, et al: Improvement of hepatorenal syndrome with extracorporeal albumin dialysis MARS: Results of a prospective, randomized, controlled clinical trial. Liver Transpl 6: 277-286, 2000. (Pubitemid 30317221)
25. Hassanein TI, Tofteng F, Brown RS Jr, et al: Randomized controlled study of extracorporeal albumin dialysis for hepatic encephalopathy in advanced cirrhosis. Hepatology 46: 1853-1862, 2007.
26. El Banayosy A, Kizner L, Schueler V, Bergmeier S, Cobaugh D, Koerfer R: The role of MARS in patients suffering from hypoxic liver failure secondary to cardiogenic shock. ITBM RBM 23(Suppl. 1): 61-66, 2002.
27. Heemann U, Treichel U, Loock J, et al: Albumin dialysis in cirrhosis with superimposed acute liver injury: A prospective, controlled study. Hepatology 36(4 Pt 1): 949-958, 2002.
28. Schmidt LE, Wang LP, Hansen BA, Larsen FS: Systemic hemodynamic effects of treatment with the molecular adsorbents recirculating system in patients with hyperacute liver failure: A prospective controlled trial. Liver Transpl 9: 290-297, 2003. (Pubitemid 36322332)
29. Laleman W, Wilmer A, Evenepoel P, et al: Effect of the molecular adsorbent recirculating system and Prometheus devices on systemic haemodynamics and vasoactive agents in patients with acute-on-chronic alcoholic liver failure. Crit Care 10: R108, 2006.
30. Sarin SK, Kumar A, Almeida JA, et al: Acute-on-chronic liver failure: Consensus recommendations of the Asian Pacific Association for the study of the liver (APASL). Hepatol Int 3: 269-282, 2009.
31. O'Grady JG, Schalm SW, Williams R: Acute liver failure: Redefining the syndromes. Lancet 342: 273-275, 1993. (Pubitemid 23224421)
32. Hessel FP, Mitzner SR, Rief J, Gress S, Guellstorff B, Wasem J: Economic evaluation of MARS-preliminary results on survival and quality of life. Liver 22(Suppl. 2): 26-29, 2002.
33. K huroo MS, Khuroo MS, Farahat KL: Molecular adsorbent recirculating system for acute and acute-on-chronic liver failure: A meta-analysis. Liver Transpl 10: 1099-1106, 2004. (Pubitemid 39248406)
34. Atienza Merino G: [Evaluation of extracorporeal liver support systems in the treatment of liver failure. A systematic review]. Gastroenterol Hepatol 33: 352-362, 2010.
35. Stange J: Meta-analysis in albumin dialysis: Are we really ready for it? Liver Transpl 10 1107-1108 rfpy1 2004 (Pubitemid 39248407)
36. Bomzon A, Holt S, Moore K: Bile acids, oxidative stress, and renal function in biliary obstruction. Semin Nephrol 17: 549-562, 1997. (Pubitemid 27465012)
37. Chieco P, Romagnoli E, Aicardi G, Suozzi A, Forti GC, Roda A: Apoptosis induced in rat hepatocytes by in vivo exposure to taurochenodeoxycholate. Histochem J 29: 875-883, 1997. (Pubitemid 28062674)
38. Drexler K, Baustian C, Richter G, Ludwig J, Ramlow W, Mitzner S: Albumin dialysis molecular adsorbents recirculating system: Impact of dialysate albumin concentration on detoxification efficacy. Ther Apher Dial 13: 393-398, 2009.