Another case of acute cardiopulmonary toxicity with cord blood infusion: Is dextran the culprit?

Transfusion

Volumn 52, Issue 1, 2012, Pages 207-208

  Choi, Sung ^a   Hoffmann, Sandra ^b   Cooling, Laura ^b  

^a UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; DEXTRAN 40; DIPHENHYDRAMINE; HYDROCORTISONE; IPRATROPIUM BROMIDE; LORAZEPAM; SALBUTAMOL; TROPONIN;

ACUTE BIPHENOTYPIC LEUKEMIA; ACUTE CARDIOPULMONARY TOXICITY; ADOLESCENT; BLOOD TRANSFUSION; CARDIOTOXICITY; CASE REPORT; CHEST TIGHTNESS; DYSPNEA; ECHOCARDIOGRAPHY; FEMALE; HEART LEFT VENTRICLE FUNCTION; HUMAN; HYPERTENSION; HYPOKINESIA; LETTER; LUNG TOXICITY; NAUSEA; PRACTICE GUIDELINE; QT PROLONGATION; TACHYCARDIA; TACHYPNEA; UMBILICAL CORD BLOOD; URTICARIA; VOMITING; WHEEZING;

ADOLESCENT; ADULT; AGED; BLOOD TRANSFUSION; CARDIOVASCULAR DISEASES; DEXTRANS; FEMALE; FETAL BLOOD; HUMANS; INFUSION PUMPS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84855385595     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2011.03424.x     Document Type: Letter

References (5)

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2. Barker JN, Abboud M, Rice RD, Hawke R, Schaible A, Heller G, La Russa V, Scaradavou A,. A "no-wash" albumin-dextran dilution strategy for cord blood unit thaw: high rate of engraftment and a low incidence of serious infusion reactions. Biol Blood Marrow Transplant 2009; 15: 1596-602.
3. Miller JP,. A centralized cord blood registry to facilitate allogenic, unrelated cord blood transplantation, BB-IND #7555 Safety Report. National Marrow Donor Program, Minneapolis, MN: July 2009.
4. Ma RW, Kwan JM, Ma DD, Fay KC,. Acute life-threatening cardiovascular toxicity with umbilical cord blood infusion: the role of dextran. Am J Hematol 2010; 85: 722-4.
5. Zinderman CE, Landow L, Wise RP,. Anaphylactoid reactions to Dextran 40 and 70: reports to the United States Food and Drug Administration, 1969 to 2004. J Vasc Surg 2006; 43: 1004-9.