-
1
-
-
33846935228
-
Unique human tumor antigens: Immunobiology and use in clinical trials
-
Parmiani G, De Filippo A, Novellino L, Castelli C. Unique human tumor antigens: immunobiology and use in clinical trials. J Immunol 2007;178:1975-9. (Pubitemid 46233392)
-
(2007)
Journal of Immunology
, vol.178
, Issue.4
, pp. 1975-1979
-
-
Parmiani, G.1
De Filippo, A.2
Novellino, L.3
Castelli, C.4
-
4
-
-
0038181111
-
+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma
-
Mortarini R, Piris A, Maurichi A, Molla A, Bersani I, Bono A, et al. Lack of terminally differentiated tumor-specific CD8+ T cells at tumor site in spite of antitumor immunity to self-antigens in human metastatic melanoma. Cancer Res 2003;63:2535-45. (Pubitemid 36605194)
-
(2003)
Cancer Research
, vol.63
, Issue.10
, pp. 2535-2545
-
-
Mortarini, R.1
Piris, A.2
Maurichi, A.3
Molla, A.4
Bersani, I.5
Bono, A.6
Bartoli, C.7
Santinami, M.8
Lombardo, C.9
Ravagnani, F.10
Cascinelli, N.11
Parmiani, G.12
Anichini, A.13
-
5
-
-
24344436369
-
Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance
-
DOI 10.1038/nature03954, PII N03954
-
Willimsky G, Blankenstein T. Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance. Nature 2005;437:141-6. (Pubitemid 41613441)
-
(2005)
Nature
, vol.437
, Issue.7055
, pp. 141-146
-
-
Willimsky, G.1
Blankenstein, T.2
-
6
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
DOI 10.1126/science.1129003
-
Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006;314:126-9. (Pubitemid 44547756)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
Royal, R.E.7
Topalian, S.L.8
Kammula, U.S.9
Restifo, N.P.10
Zheng, Z.11
Nahvi, A.12
De Vries, C.R.13
Rogers-Freezer, L.J.14
Mavroukakis, S.A.15
Rosenberg, S.A.16
-
7
-
-
33845593715
-
Temporal cross-talk between TCR and STAT signals for CD8 T cell effector differentiation
-
DOI 10.1002/eji.200636347
-
Verdeil G, Chaix J, Schmitt-Verhulst AM, Auphan-Anezin N. Temporal cross-talk between TCR and STAT signals for CD8 T cell effector differentiation. Eur J Immunol 2006;36:3090-100. (Pubitemid 44932711)
-
(2006)
European Journal of Immunology
, vol.36
, Issue.12
, pp. 3090-3100
-
-
Verdeil, G.1
Chaix, J.2
Schmitt-Verhulst, A.-M.3
Auphan-Anezin, N.4
-
8
-
-
33746348281
-
The roles for cytokines in the generation and maintenance of regulatory T cells
-
DOI 10.1111/j.0105-2896.2006.00407.x
-
Wan YY, Flavell RA. The roles for cytokines in the generation and maintenance of regulatory T cells. Immunol Rev 2006;212:114-30. (Pubitemid 44116704)
-
(2006)
Immunological Reviews
, vol.212
, pp. 114-130
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
9
-
-
36749004944
-
Mechanisms controlling cell cycle exit upon terminal differentiation
-
DOI 10.1016/j.ceb.2007.10.004, PII S0955067407001512, Cell Differentiation / Cell Division, Growth and Death
-
Buttitta LA, Edgar BA. Mechanisms controlling cell cycle exit upon terminal differentiation. Curr Opin Cell Biol 2007;19:697-704. (Pubitemid 350216428)
-
(2007)
Current Opinion in Cell Biology
, vol.19
, Issue.6
, pp. 697-704
-
-
Buttitta, L.A.1
Edgar, B.A.2
-
10
-
-
20444499355
-
+ T cells
-
DOI 10.1172/JCI24480
-
Gattinoni L, Klebanoff CA, Palmer DC, Wrzesinski C, Kerstann K, Yu Z, et al. Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells. J Clin Invest 2005;115:1616-26. (Pubitemid 40814670)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.6
, pp. 1616-1626
-
-
Gattinoni, L.1
Klebanoff, C.A.2
Palmer, D.C.3
Wrzesinski, C.4
Kerstann, K.5
Yu, Z.6
Finkelstein, S.E.7
Theoret, M.R.8
Rosenberg, S.A.9
Restifo, N.P.10
-
11
-
-
70449393651
-
MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages
-
Aziz A, Soucie E, Sarrazin S, Sieweke MH. MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages. Science 2009;326:867-71.
-
(2009)
Science
, vol.326
, pp. 867-871
-
-
Aziz, A.1
Soucie, E.2
Sarrazin, S.3
Sieweke, M.H.4
-
12
-
-
33645759947
-
STAT5-mediated signals sustain a TCR-initiated gene expression program toward differentiation of CD8 T cell effectors
-
Verdeil G, Puthier D, Nguyen C, Schmitt-Verhulst AM, Auphan-Anezin N. STAT5-mediated signals sustain a TCR-initiated gene expression program toward differentiation of CD8 T cell effectors. J Immunol 2006;176:4834-42.
-
(2006)
J Immunol
, vol.176
, pp. 4834-4842
-
-
Verdeil, G.1
Puthier, D.2
Nguyen, C.3
Schmitt-Verhulst, A.M.4
Auphan-Anezin, N.5
-
13
-
-
55449105991
-
Maximal STAT5-induced proliferation and self-renewal at intermediate STAT5 activity levels
-
Wierenga AT, Vellenga E, Schuringa JJ. Maximal STAT5-induced proliferation and self-renewal at intermediate STAT5 activity levels. Mol Cell Biol 2008;28:6668-80.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6668-6680
-
-
Wierenga, A.T.1
Vellenga, E.2
Schuringa, J.J.3
-
14
-
-
33645518844
-
An inducible mouse model of melanoma expressing a defined tumor antigen
-
Huijbers IJ, Krimpenfort P, Chomez P, van der Valk MA, Song JY, Inderberg-Suso EM, et al. An inducible mouse model of melanoma expressing a defined tumor antigen. Cancer Res 2006;66:3278-86.
-
(2006)
Cancer Res
, vol.66
, pp. 3278-3286
-
-
Huijbers, I.J.1
Krimpenfort, P.2
Chomez, P.3
Van Der Valk, M.A.4
Song, J.Y.5
Inderberg-Suso, E.M.6
-
15
-
-
77951708030
-
Tumor-initiated inflammation overrides protective adaptive immunity in an induced melanoma model in mice
-
Soudja SM, Wehbe M, Mas A, Chasson L, de Tenbossche CP, Huijbers I, et al. Tumor-initiated inflammation overrides protective adaptive immunity in an induced melanoma model in mice. Cancer Res 2010;70:3515-25.
-
(2010)
Cancer Res
, vol.70
, pp. 3515-3525
-
-
Soudja, S.M.1
Wehbe, M.2
Mas, A.3
Chasson, L.4
De Tenbossche, C.P.5
Huijbers, I.6
-
16
-
-
38449096756
-
CD8 T cell help for innate antitumor immunity
-
Shanker A, Verdeil G, Buferne M, Inderberg-Suso EM, Puthier D, Joly F, et al. CD8 T cell help for innate antitumor immunity. J Immunol 2007;179:6651-62.
-
(2007)
J Immunol
, vol.179
, pp. 6651-6662
-
-
Shanker, A.1
Verdeil, G.2
Buferne, M.3
Inderberg-Suso, E.M.4
Puthier, D.5
Joly, F.6
-
17
-
-
0242610921
-
The Generation of a Conditional Reporter that Enables Bioluminescence Imaging of Cre/loxP-Dependent Tumorigenesis in Mice
-
Lyons SK, Meuwissen R, Krimpenfort P, Berns A. The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice. Cancer Res 2003;63:7042-6. (Pubitemid 37413436)
-
(2003)
Cancer Research
, vol.63
, Issue.21
, pp. 7042-7046
-
-
Lyons, S.K.1
Meuwissen, R.2
Krimpenfort, P.3
Berns, A.4
-
18
-
-
0029566108
-
A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
-
Schwenk F, Baron U, Rajewsky K. A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res 1995;23:5080-1. (Pubitemid 26012492)
-
(1995)
Nucleic Acids Research
, vol.23
, Issue.24
, pp. 5080-5081
-
-
Schwenk, F.1
Baron, U.2
Rajewsky, K.3
-
19
-
-
0034662159
-
Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages
-
Faust N, Varas F, Kelly LM, Heck S, Graf T. Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages. Blood 2000;96:7190-26.
-
(2000)
Blood
, vol.96
, pp. 7190-7226
-
-
Faust, N.1
Varas, F.2
Kelly, L.M.3
Heck, S.4
Graf, T.5
-
20
-
-
0142185336
-
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
-
DOI 10.1016/S0022-1759(03)00265-5
-
Betts MR, Brenchley JM, Price DA, De Rosa SC, Douek DC, Roederer M, et al. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J Immunol Methods 2003;281:65-78. (Pubitemid 37324571)
-
(2003)
Journal of Immunological Methods
, vol.281
, Issue.1-2
, pp. 65-78
-
-
Betts, M.R.1
Brenchley, J.M.2
Price, D.A.3
De Rosa, S.C.4
Douek, D.C.5
Roederer, M.6
Koup, R.A.7
-
21
-
-
0028987560
-
Individual differences in the orientation of the cytolytic T cell response against mouse tumor P815
-
Brichard VG, Warnier G, Van Pel A, Morlighem G, Lucas S, Boon T. Individual differences in the orientation of the cytolytic T cell response against mouse tumor P815. Eur J Immunol 1995;25:664-71.
-
(1995)
Eur J Immunol
, vol.25
, pp. 664-671
-
-
Brichard, V.G.1
Warnier, G.2
Van Pel, A.3
Morlighem, G.4
Lucas, S.5
Boon, T.6
-
22
-
-
19944431828
-
Stat5 tetramer formation is associated with leukemogenesis
-
DOI 10.1016/j.ccr.2004.12.010, PII S1535610804003721
-
Moriggl R, Sexl V, Kenner L, Duntsch C, Stangl K, Gingras S, et al. Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell 2005;7:87-99. (Pubitemid 40126385)
-
(2005)
Cancer Cell
, vol.7
, Issue.1
, pp. 87-99
-
-
Moriggl, R.1
Sexl, V.2
Kenner, L.3
Duntsch, C.4
Stangl, K.5
Gingras, S.6
Hoffmeyer, A.7
Bauer, A.8
Piekorz, R.9
Wang, D.10
Bunting, K.D.11
Wagner, E.F.12
Sonneck, K.13
Valent, P.14
Ihle, J.N.15
Beug, H.16
-
23
-
-
0031836964
-
Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation
-
Onishi M, Nosaka T, Misawa K, Mui AL, Gorman D, McMahon M, et al. Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation. Mol Cell Biol 1998;18:3871-9. (Pubitemid 28287910)
-
(1998)
Molecular and Cellular Biology
, vol.18
, Issue.7
, pp. 3871-3879
-
-
Onishi, M.1
Nosaka, T.2
Misawa, K.3
Mui, A.L.-F.4
Gorman, D.5
McMahon, M.6
Miyajima, A.7
Kitamura, T.8
-
24
-
-
33748051700
-
Different lineages of P1A-expressing cancer cells use divergent modes of immune evasion for T-cell adoptive therapy
-
DOI 10.1158/0008-5472.CAN-06-0279
-
Bai XF, Liu JQ, Joshi PS, Wang L, Yin L, Labanowska J, et al. Different lineages of P1A-expressing cancer cells use divergent modes of immune evasion for T-cell adoptive therapy. Cancer Res 2006;66:8241-9. (Pubitemid 44299193)
-
(2006)
Cancer Research
, vol.66
, Issue.16
, pp. 8241-8249
-
-
Bai, X.-F.1
Liu, J.-Q.2
Joshi, P.S.3
Wang, L.4
Yin, L.5
Labanowska, J.6
Heerema, N.7
Zheng, P.8
Liu, Y.9
-
25
-
-
33645465526
-
Selective stimulation of T cell subsets with antibody-cytokine immune complexes
-
Boyman O, Kovar M, Rubinstein MP, Surh CD, Sprent J. Selective stimulation of T cell subsets with antibody-cytokine immune complexes. Science 2006;311:1924-7.
-
(2006)
Science
, vol.311
, pp. 1924-1927
-
-
Boyman, O.1
Kovar, M.2
Rubinstein, M.P.3
Surh, C.D.4
Sprent, J.5
-
26
-
-
55949105361
-
Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy
-
Verdeil G, Marquardt K, Surh CD, Sherman LA. Adjuvants targeting innate and adaptive immunity synergize to enhance tumor immunotherapy. Proc Natl Acad Sci U S A 2008;105:16683-8.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16683-16688
-
-
Verdeil, G.1
Marquardt, K.2
Surh, C.D.3
Sherman, L.A.4
-
27
-
-
43749112760
-
Vascular normalization in Rgs5-deficient tumours promotes immune destruction
-
DOI 10.1038/nature06868, PII NATURE06868
-
Hamzah J, Jugold M, Kiessling F, Rigby P, Manzur M, Marti HH, et al. Vascular normalization in Rgs5-deficient tumours promotes immune destruction. Nature 2008;453:410-4. (Pubitemid 351693122)
-
(2008)
Nature
, vol.453
, Issue.7193
, pp. 410-414
-
-
Hamzah, J.1
Jugold, M.2
Kiessling, F.3
Rigby, P.4
Manzur, M.5
Marti, H.H.6
Rabie, T.7
Kaden, S.8
Grone, H.-J.9
Hammerling, G.J.10
Arnold, B.11
Ganss, R.12
-
28
-
-
79952281795
-
Improving cancer immunotherapy by targeting tumor-induced immune suppression
-
Stewart TJ, Smyth MJ. Improving cancer immunotherapy by targeting tumor-induced immune suppression. Cancer Metastasis Rev 2011;30:125-40.
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 125-140
-
-
Stewart, T.J.1
Smyth, M.J.2
-
29
-
-
33644646423
-
The role of stroma in immune recognition and destruction of well-established solid tumors
-
DOI 10.1016/j.coi.2006.01.004, PII S0952791506000069, Lymphocyte Development / Tumor Immunology
-
Yu P, Rowley DA, Fu YX, Schreiber H. The role of stroma in immune recognition and destruction of well-established solid tumors. Curr Opin Immunol 2006;18:226-31. (Pubitemid 43327307)
-
(2006)
Current Opinion in Immunology
, vol.18
, Issue.2
, pp. 226-231
-
-
Yu, P.1
Rowley, D.A.2
Fu, Y.-X.3
Schreiber, H.4
-
30
-
-
80051698813
-
Determinants of successful CD8+T cell adoptive immunotherapy for large established tumors in mice
-
Klebanoff CA, Gattinoni L, Palmer DC, Muranski P, Ji Y, Hinrichs CS, et al. Determinants of successful CD8+T cell adoptive immunotherapy for large established tumors in mice. Clin Cancer Res 2011;17:5343-52.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5343-5352
-
-
Klebanoff, C.A.1
Gattinoni, L.2
Palmer, D.C.3
Muranski, P.4
Ji, Y.5
Hinrichs, C.S.6
-
31
-
-
63549104097
-
Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma
-
Nevala WK, Vachon CM, Leontovich AA, Scott CG, Thompson MA, Markovic SN. Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma. Clin Cancer Res 2009;15:1931-9.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1931-1939
-
-
Nevala, W.K.1
Vachon, C.M.2
Leontovich, A.A.3
Scott, C.G.4
Thompson, M.A.5
Markovic, S.N.6
-
32
-
-
79960630266
-
Disrupted lymph node and splenic stroma in mice with induced inflammatory melanomas is associated with impaired recruitment of T and dendritic cells
-
Soudja SM, Henri S, Mello M, Chasson L, Mas A, Wehbe M, et al. Disrupted lymph node and splenic stroma in mice with induced inflammatory melanomas is associated with impaired recruitment of T and dendritic cells. PLoS One 2011;6:e22639.
-
(2011)
PLoS One
, vol.6
-
-
Soudja, S.M.1
Henri, S.2
Mello, M.3
Chasson, L.4
Mas, A.5
Wehbe, M.6
-
33
-
-
3042844293
-
Cancer immunotherapy: A treatment for the masses
-
DOI 10.1126/science.1100369
-
Blattman JN, Greenberg PD. Cancer immunotherapy: a treatment for the masses. Science 2004;305:200-5. (Pubitemid 38886725)
-
(2004)
Science
, vol.305
, Issue.5681
, pp. 200-205
-
-
Blattman, J.N.1
Greenberg, P.D.2
-
35
-
-
4744351702
-
Replicative senescence of CD8 T cells: Potential effects on cancer immune surveillance and immunotherapy
-
DOI 10.1007/s00262-004-0508-x
-
Effros RB. Replicative senescence of CD8 T cells: potential effects on cancer immune surveillance and immunotherapy. Cancer Immunol Immunother 2004;53:925-33. (Pubitemid 39312659)
-
(2004)
Cancer Immunology, Immunotherapy
, vol.53
, Issue.10
, pp. 925-933
-
-
Effros, R.B.1
-
36
-
-
74549162832
-
Prolonged interleukin-2Ralpha expression on virus-specific CD8(+) T cells favors terminal-effector differentiation in vivo
-
Kalia V, Sarkar S, Subramaniam S, Haining WN, Smith KA, Ahmed R. Prolonged interleukin-2Ralpha expression on virus-specific CD8(+) T cells favors terminal-effector differentiation in vivo. Immunity 2010;32:91-103.
-
(2010)
Immunity
, vol.32
, pp. 91-103
-
-
Kalia, V.1
Sarkar, S.2
Subramaniam, S.3
Haining, W.N.4
Smith, K.A.5
Ahmed, R.6
-
37
-
-
15444374646
-
+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
-
DOI 10.1084/jem.20041982
-
Setoguchi R, Hori S, Takahashi T, Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med 2005;201:723-35. (Pubitemid 40395118)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.5
, pp. 723-735
-
-
Setoguchi, R.1
Hori, S.2
Takahashi, T.3
Sakaguchi, S.4
-
38
-
-
79251565807
-
A role for IL-15 in the migration of effector CD8 T cells to the lung airways following influenza infection
-
Verbist KC, Cole CJ, Field MB, Klonowski KD. A role for IL-15 in the migration of effector CD8 T cells to the lung airways following influenza infection. J Immunol 2011;186:174-82.
-
(2011)
J Immunol
, vol.186
, pp. 174-182
-
-
Verbist, K.C.1
Cole, C.J.2
Field, M.B.3
Klonowski, K.D.4
-
40
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu H, Pardoll D, Jove R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer 2009;9:798-809.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
41
-
-
78649916060
-
Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects
-
Kujawski M, Zhang C, Herrmann A, Reckamp K, Scuto A, Jensen M, et al. Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects. Cancer Res 2010;70:9599-610.
-
(2010)
Cancer Res
, vol.70
, pp. 9599-9610
-
-
Kujawski, M.1
Zhang, C.2
Herrmann, A.3
Reckamp, K.4
Scuto, A.5
Jensen, M.6
-
42
-
-
79951682333
-
Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
-
Yang XP, Ghoreschi K, Steward-Tharp SM, Rodriguez-Canales J, Zhu J, Grainger JR, et al. Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5. Nat Immunol 2011;12:247-54.
-
(2011)
Nat Immunol
, vol.12
, pp. 247-254
-
-
Yang, X.P.1
Ghoreschi, K.2
Steward-Tharp, S.M.3
Rodriguez-Canales, J.4
Zhu, J.5
Grainger, J.R.6
-
43
-
-
70349438847
-
Engineering lymphocyte subsets: Tools, trials and tribulations
-
June CH, Blazar BR, Riley JL. Engineering lymphocyte subsets: tools, trials and tribulations. Nat Rev Immunol 2009;9:704-16.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 704-716
-
-
June, C.H.1
Blazar, B.R.2
Riley, J.L.3
-
44
-
-
55249087037
-
Resistance of mature T cells to oncogene transformation
-
Newrzela S, Cornils K, Li Z, Baum C, Brugman MH, Hartmann M, et al. Resistance of mature T cells to oncogene transformation. Blood 2008;112:2278-86.
-
(2008)
Blood
, vol.112
, pp. 2278-2286
-
-
Newrzela, S.1
Cornils, K.2
Li, Z.3
Baum, C.4
Brugman, M.H.5
Hartmann, M.6
-
45
-
-
78049268109
-
Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival
-
Hand TW, Cui W, Jung YW, Sefik E, Joshi NS, Chandele A, et al. Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival. Proc Natl Acad Sci U S A 2010;107:16601-6.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16601-16606
-
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Hand, T.W.1
Cui, W.2
Jung, Y.W.3
Sefik, E.4
Joshi, N.S.5
Chandele, A.6
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