Economic and radiation costs of initial imaging approaches after a child's first febrile urinary tract infection

Clinical Pediatrics

Volumn 51, Issue 1, 2012, Pages 23-30

  Routh, Jonathan C ^a   Grant, Frederick D ^a   Kokorowski, Paul J ^a   Nelson, Caleb P ^a   Fahey, Frederic H ^a   Treves, S Ted ^a   Lee, Richard S ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

imaging; pediatrics; urinary tract infection; vesicoureteral reflux

Indexed keywords

SUCCIMER TC 99M;

ARTICLE; CHILD; CHILDHOOD DISEASE; COHORT ANALYSIS; CYSTOGRAPHY; ECHOGRAPHY; FEVER; HEALTH CARE COST; HUMAN; INFANT; INTERMETHOD COMPARISON; KIDNEY SCINTISCANNING; MICTURITION CYSTOURETHROGRAPHY; MODEL; PRESCHOOL CHILD; RADIATION DOSE; SENSITIVITY ANALYSIS; URINARY TRACT INFECTION;

ALGORITHMS; COST-BENEFIT ANALYSIS; DECISION SUPPORT TECHNIQUES; FEMALE; FEVER; HUMANS; INFANT; MALE; RADIATION DOSAGE; RADIOPHARMACEUTICALS; SENSITIVITY AND SPECIFICITY; TECHNETIUM TC 99M DIMERCAPTOSUCCINIC ACID; ULTRASONOGRAPHY; URINARY TRACT INFECTIONS; VESICO-URETERAL REFLUX;

EID: 84855361260     PISSN: 00099228     EISSN: 19382707     Source Type: Journal    
DOI: 10.1177/0009922811417294     Document Type: Article

References (34)

1. Pediatrics. 1999 ; 103 (4 pt 1). 843-852
2. Cohen AL, Rivara FP, Davis R, Christakis DA. Compliance with guidelines for the medical care of first urinary tract infections in infants: a population-based study. Pediatrics. 2005 ; 115: 1474-1478 (Pubitemid 43843153)
3. Pohl HG, Belman AB. The "top-down" approach to the evaluation of children with febrile urinary tract infection. Adv Urol. 2009 ;: 783409
4. Riccabona M, Avni FE, Blickman JG, et al. Imaging recommendations in paediatric uroradiology: minutes of the ESPR workgroup session on urinary tract infection, fetal hydronephrosis, urinary tract ultrasonography and voiding cystourethrography, Barcelona, Spain, June 2007. Pediatr Radiol. 2008 ; 38: 138-145
5. Preda I, Jodal U, Sixt R, Stokland E, Hansson S. Normal dimercaptosuccinic acid scintigraphy makes voiding cystourethrography unnecessary after urinary tract infection. J Pediatr. 2007 ; 151: 581-584
6. Meeks JJ, Altman DG, Bradburn MJ Systematic Reviews in Health Care: Meta-Analysis in Context. Egger M Smith GD Altman DG, ed. London, UK: BMJ Publishing Group ; 2001: 285-312.
7. Report No. 80: Radiation Dose to Patients From Radiopharmaceuticals. London, UK: Pergamon Press ; 1997:
8. Ward VL. Patient dose reduction during voiding cystourethrography. Pediatr Radiol. 2006 ; 36 (suppl 2). 168-172
9. Ward VL, Strauss KJ, Barnewolt CE, et al. Pediatric radiation exposure and effective dose reduction during voiding cystourethrography. Radiology. 2008 ; 249: 1002-1009
10. Fazel R, Krumholz HM, Wang Y, et al. Exposure to low-dose ionizing radiation from medical imaging procedures. N Engl J Med. 2009 ; 361: 850-857
11. Centers for Medicare and Medicaid Services. Physician fee schedule. 2009. http://www.cms.hhs.gov/PhysicianFeeSched/. Accessed July 11, 2011.
12. Lund JL, Yabroff KR, Ibuka Y, et al. Inventory of data sources for estimating health care costs in the United States. Med Care. 2009 ; 47 (7 suppl 1). S127 - S142
13. Riley GF. Administrative and claims records as sources of health care cost data. Med Care. 2009 ; 47 (7 suppl 1). S51 - S55
14. Ellison JS, Maxfield CM, Wiener JS. Voiding cystography practices and preferences of North American pediatric urologists. J Urol. 2009 ; 182: 299-304
15. Ferrer FA, McKenna PH, Hochman HI, Herndon A. Results of a vesicoureteral reflux practice pattern survey among American Academy of Pediatrics, Section on Pediatric Urology members. J Urol. 1998 ; 160: 1031-1037
16. Herz D, Merguerian P, McQuiston L, Danielson C, Gheen M, Brenfleck L. 5-Year prospective results of dimercapto-succinic acid imaging in children with febrile urinary tract infection: proof that the top-down approach works. J Urol. 2011 ; 184 (4 suppl). 1703-1709
17. Brenner DJ, Hall EJ. Computed tomography-an increasing source of radiation exposure. N Engl J Med. 2007 ; 357: 2277-2284 (Pubitemid 350190758)
18. Health Risks From Exposure to Low Levels of Ionizing Radiation: BEIR VII, Phase 2. Washington, DC: National Academies Press ; 2006:
19. Preston DL, Cullings H, Suyama A, et al. Solid cancer incidence in atomic bomb survivors exposed in utero or as young children. J Natl Cancer Inst. 2008 ; 100: 428-436 (Pubitemid 351480515)
20. Smith-Bindman R, Miglioretti DL, Larson EB. Rising use of diagnostic medical imaging in a large integrated health system. Health Aff (Millwood). 2008 ; 27: 1491-1502
21. Amis ES, Butler PF, Applegate KE, et al. American College of Radiology white paper on radiation dose in medicine. J Am Coll Radiol. 2007 ; 4: 272-284 (Pubitemid 46671375)
22. Strauss KJ, Kaste SC. The ALARA (as low as reasonably achievable) concept in pediatric interventional and fluoroscopic imaging: striving to keep radiation doses as low as possible during fluoroscopy of pediatric patients-a white paper executive summary. Pediatr Radiol. 2006 ; 36 (suppl 2). 110-112 (Pubitemid 351601470)
23. Cost-Effectiveness in Health and Medicine. Gold MR Siegel JE Russell LB Weinstein MC, ed. New York, NY: Oxford University Press ; 1996:
24. Ajdinovic B, Jaukovic L, Krstic Z, Dopuda M. Impact of micturating cystourethrography and DMSA renal scintigraphy on the investigation scheme in children with urinary tract infection. Ann Nucl Med. 2008 ; 22: 661-665
25. Aktas GE, Inanir S, Turoglu HT. Renal cortical involvement in children with first UTI: does it differ in the presence of primary VUR?. Ann Nucl Med. 2008 ; 22: 877-881
26. Brader P, Riccabona M, Schwarz T, Seebacher U, Ring E. Value of comprehensive renal ultrasound in children with acute urinary tract infection for assessment of renal involvement: comparison with DMSA scintigraphy and final diagnosis. Eur Radiol. 2008 ; 18: 2981-2989
27. Gordon I, Barkovics M, Pindoria S, Cole TJ, Woolf AS. Primary vesicoureteric reflux as a predictor of renal damage in children hospitalized with urinary tract infection: a systematic review and meta-analysis. J Am Soc Nephrol. 2003 ; 14: 739-744 (Pubitemid 36246019)
28. Hansson S, Dhamey M, Sigstrom O, et al. Dimercapto-succinic acid scintigraphy instead of voiding cystourethrography for infants with urinary tract infection. J Urol. 2004 ; 172: 1071-1073 (Pubitemid 39096466)
29. Lee MD, Lin CC, Huang FY, Tsai TC, Huang CT, Tsai JD. Imaging young children with a first febrile urinary tract infection for high-grade vesicoureteral reflux with renal ultrasound scanning and technetium-99m-labeled dimercaptosuccinic acid scanning. J Pediatr. 2009 ; 154: 797-802
30. Levart TK, Kljucevsek D, Kenig A, Kenda RB. Sensitivity of ultrasonography in detecting renal parenchymal defects: 6 years' follow-up. Pediatr Nephrol. 2009 ; 24: 1193-1197
31. Moorthy I, Easty M, McHugh K, Ridout D, Biassoni L, Gordon I. The presence of vesicoureteric reflux does not identify a population at risk for renal scarring following a first urinary tract infection. Arch Dis Child. 2005 ; 90: 733-736 (Pubitemid 40922508)
32. Muller L, Preda I, Jacobsson B, et al. Ultrasonography as predictor of permanent renal damage in infants with urinary tract infection. Acta Paediatr. 2009 ; 98: 1156-1161
33. Siomou E, Giapros V, Fotopoulos A, et al. Implications of 99mTc-DMSA scintigraphy performed during urinary tract infection in neonates. Pediatrics. 2009 ; 124: 881-887
34. Tseng MH, Lin WJ, Lo WT, Wang SR, Chu ML, Wang CC. Does a normal DMSA obviate the performance of voiding cystourethrography in evaluation of young children after their first urinary tract infection?. J Pediatr. 2007 ; 150: 96-99