RNA/DNA hybrid binding affinity determines telomerase template- translocation efficiency

EMBO Journal

Volumn 31, Issue 1, 2012, Pages 150-161

  Qi, Xiaodong ^a   Xie, Mingyi ^a,c   Brown, Andrew F ^a   Bley, Christopher J ^a   Podlevsky, Joshua D ^b   Chen, Julian J L ^a,b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c YALE UNIVERSITY   (United States)

Author keywords

processivity; reverse transcriptase; telomere; template translocation

Indexed keywords

RNA; SINGLE STRANDED DNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; TELOMERIC DNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DNA BINDING; DNA RNA HYBRIDIZATION; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; GENE TRANSLOCATION; HUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; RNA BINDING; TEMPLATE TRANSLOCATION; TURNOVER TIME; WILD TYPE;

BASE PAIRING; BINDING SITES; DNA; HUMANS; RNA; TELOMERASE; TEMPLATES, GENETIC; TRANSLOCATION, GENETIC;

EID: 84855359738     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.363     Document Type: Article

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