Sustained TRPA1 activation in vivo

Acta Physiologica

Volumn 204, Issue 2, 2012, Pages 248-254

  Koivisto, A ^a  

^a ORION CORPORATION   (Finland)

Author keywords

4 hydroxynonenal; Mechanical hypersensitivity; Neuropathic pain; Patch clamp; Prostaglandin J2; TRPA1

Indexed keywords

4 HYDROXYNONENAL; CYSTEINE; FORMALDEHYDE; GLUTATHIONE PEROXIDASE 1; LYSINE; PROSTAGLANDIN J2; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1;

AMINO TERMINAL SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHRONIC PAIN; COVALENT BOND; ENZYME ACTIVITY; HUMAN; HYPERSENSITIVITY; IN VIVO STUDY; NEUROPATHIC PAIN; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; REVIEW;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CHRONIC PAIN; HUMANS; MEMBRANE POTENTIALS; MICE; MODELS, ANIMAL; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; RATS; TRANSIENT RECEPTOR POTENTIAL CHANNELS; TRPC CATION CHANNELS;

EID: 84855354695     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2011.02318.x     Document Type: Review

References (58)

1. Andersson, D.A., Gentry, C., Moss, S. & Bevan, S. 2008. Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress. J Neurosci28, 2485-2494.
2. Bandell, M., Story, G.M., Hwang, S.W., Viswanath, V., Eid, S.R., Petrus, M.J., Earley, T.J. & Patapoutian, A. 2004. Noxious cold channel TRPA1 is activated by pungent compounds and bradykinin. Neuron41, 849-857.
3. Bang, S., Kim, K.Y., Yoo, S. & Hwang, S.W. 2007. Transient receptor potential A1mediates acetaldehyde-evoked pain sensation. Eur J Neurosci26, 2516-2523.
4. Bautista, D.M., Movahed, P., Hinman, A., Axelsson, H.E., Sterner, O., Högestätt, E.D., Julius, D., Jordt, S.E. & Zygmunt, P.M. 2005. Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci USA102, 12248-12252.
5. Benhar, M., Forrester, M.T. & Stamler, J.S. 2009. Protein denitrosylation: enzymatic mechanisms and cellular functions. Nat Rev Mol Cell Biol10, 721-732.
6. Bernardo, A., Ajmone-Cat, M.A., Levi, G. & Minghetti, L. 2003. 15-deoxy-delta-12, 14-prostaglandin J2 regulates the functional state and the survival of microglial cels through multiple molecular mechanisms. J Neurochem87, 742-751.
7. del Camino, D., Murphy, S., Heiry, M., Barrett, L.B., Earley, T.J., Cook, C.A., Petrus, M.J., Zhao, M., D'Ámours, M., Deering, N. et al. 2010. TRPA1 contributes to cold hypersensitivity. J Neurosci30, 15165-15174.
8. Chen, J. & Kym, P.R. 2009. TRPA1: the species difference. J Gen Physiol133, 623-625.
9. da Costa, D.S., Meotti, F.C., Andrade, E.L., Laeal, P.C., Motta, E.M. & Calixto, J.B. 2010. The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation. Pain148, 431-437.
10. Courteix, C., Eschalier, A. & Lavarenne, J. 1993. Streptozotocin-induced diabetic rats: bahavioural evidence for a model of chronic pain. Pain53, 81-88.
11. Cruz-Orego, L., Dhaka, A., Heurmann, R.J., Young, T.J., Montana, M.C., Cavanaugh, E.J., Kim, D. & Story, G.M. 2008. Cutaneous nociception evoked by 15-delta PGJ2 via activation of ion channel TRPA1. Mol Pain4, 30.
12. Doerner, J.F., Gisselmann, G., Hatt, H. & Wetzel, C.H. 2007. Transient receptor potential channel A1 is directly gated by calcium ions. J Biol Chem282, 13180-13189.
13. Dubuisson, D. & Dennis, S.G. 1977. The formalin test: a quantitative study of the analgesic effect of morphine, meperidine, and brain stem stimulation in rats and cats. Pain4, 161-174.
14. Eid, S.R., Crown, E.D., Moore, E.L., Liang, H.A., Choong, K., Dima, S., Henze, D.A., Kane, S.A. & Urban, M.O. 2008. HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity. Mol Pain4, 48.
15. Fang, J. & Holmgren, A. 2006. Inhibition of thioredoxin and thioredoxin reductase by 4-hydroxy-2-nonenal in vitro and in vivo. J Am Chem Soc128, 1879-1885.
16. Hardy, K.D., Cox, B.J., Milne, G.L., Yin, H. & Roberts, L.J. 2011. Nonenzymatic free radical-catalyzed generation of 15-deoxy-delta-12, 14-prostaglandin J2-like compounds (deoxy-J2-isoprostanes) in vivo. J Lipid Res52, 113-124.
17. Hinman, A., Chuang, H.H., Bautista, D.M. & Julius, D. 2006. TRP channel activation by reversible covalent modification. Proc Natl Acad Sci USA103, 19564-19568.
18. Jordt, S.E., Bautista, D.M., Chuang, H.-H., McKemy, D.D., Zygmunt, P.M., Högestätt, E.D., Meng, I.D. & Julius, D. 2004. Mustard oils and cannbinoids excite sensory nerve fibers through the TRP channel ANKTM1. Nature427, 260-265.
19. Kakkar, R., Mantha, S.V., Radhi, J., Prasad, K. & Kalra, J. 1998. Increased oxidative stress in rat liver and pancreas during progression of streptozotocin-induced diabetes. Clin Sci94, 623-632.
20. Kang, K., Pulver, S.R., Panzano, V.C., Chang, E.C., Griffith, L.C., Theobald, D.L. & Garrity, P.A. 2010. Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception. Nature464, 597-600.
21. Kerstein, P.C., del Camino, D., Moran, M.M. & Stucky, C.L. 2009. Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors. Mol Pain5, 19.
22. Kim, D., You, B., Jo, E.-K., Han, S.-K., Simon, M.I. & Lee, S.-J. 2010. NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain. Proc Natl Acad Sci USA107, 14851-14856.
23. Koivisto, A. 1997. Nonselective Cation Channels in Brown Fat Cells: Adrenergic and NO Regulation, p.112. Stockholm University, Stockholm, Sweden.
24. Kosugi, M., Nakatsuka, T., Fujita, T., Kuroda, Y. & Kumamoto, E. 2007. Activation of TRPA1 channel facilitates excitatory synaptic transmission in substantia gelatinosa neurons of the adult rat spinal cord. J Neurosci27, 4443-4451.
25. Kremeyer, B., Lopera, F., Cox, J.J., Momin, A., Rugiero, F., Marsh, S., Woods, S.G., Jones, N.G., Paterson, K.J., Fricker, F.R. et al. 2010. A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome. Neuron66, 671-680.
26. Kwan, K.Y., Allchorne, A.J., Vollrath, M.A., Christensen, A.P., Zhang, D.-S., Woolf, C.J. & Corey, D.P. 2006. TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron50, 277-289.
27. Lee, I., Kim, H.K., Kim, J.H., Chung, K. & Chung, J.M. 2007. The role of reactive oxygen species in capsaicin-induced mechanical hyperalgesia and in the activities of dorsal horn neurons. Pain133, 9-17.
28. Macpherson, L.J., Dubin, A.E., Evans, M.J., Marr, F., Schultz, P.G., Cravatt, B.F. & Patapoutian, A. 2007a. Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines. Nature445, 541-545.
29. Macpherson, L.J., Xiao, B., Kwan, K.Y., Petrus, M.J., Dubin, A.E., Hwang, S., Cravatt, B., Corey, D.P. & Patapoutian, A. 2007b. An ion channel essential for sensing chemical damage. J Neurosci27, 11412-11415.
30. Materazzi, S., Nassini, R., Andre, E., Campi, B., Amadesi, S., Trevisani, M., Bunnett, N.W., Patacchini, R. & Geppetti, P. 2008. Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1. Proc Natl Acad Sci USA105, 12045-12050.
31. McCall, W.D., Tanner, K.D. & Levine, J.D. 1996. Formalin induces biphasic activity in C-fibers in the rat. Neurosci Lett208, 45-48.
32. McNamara, C.R., Mendel-Brehm, J., Bautista, D.M., Siemens, J., Deranian, K.L., Zhao, M., Hayward, N.J., Chong, J.A., Julius, D., Moran, M.M. & Fanger, C.M. 2007. TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci USA104, 13525-13530.
33. Miyamoto, T., Dubin, A.E., Petrus, M. & Patapoutian, A. 2009. TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice. PLoS ONE4, e7596.
34. Morgado, C., Pereira-Terra, P., Cruz, C.D. & Tavares, I. 2011. Minocycline completely reverses mechanical hyperalgesia in diabetic rats through microglia-induced changes in the expression of the potassium chloride co-transporter 2 (KCC2) at the spinal cord. Diabetes, Obes Metab13, 150-159.
35. Nagata, K., Duggan, A., Kumar, G. & Garcia-Anoveros, J.G. 2005. Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing. J Neurosci25, 4052-4061.
36. Petrus, M., Peier, A.M., Bandell, M., Hwang, S.W., Huynh, T., Olney, N., Jegla, T. & Patapoutian, A. 2007. A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition. Mol Pain3, 40.
37. Price, S.A., Gardiner, N.J., Duran-Jimenez, B., Zeef, L.A., Obrosova, I.G. & Tomlinson, D.R. 2006. Thioredoxin interacting protein is increased in sensory neurons in experimental diabetes. Brain Res1116, 206-214.
38. Puig, S. & Sorkin, L.S. 1995. Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity. Pain64, 345-355.
39. Saarnilehto, M., Chapman, H., Kuokkanen, K. & Koivisto, A. 2007. Lipid peroxidation product 4-hydroxynonenal is TRPA1 agonist. In: Proceedings of Keystone Symposium on Transient Receptor Potential Ion Channel Superfamily, abstract 203 p. 55. Breckenridge, CO, USA.
40. Schulze, P.C., Yoshioka, J., Takahashi, T., He, Z., King, G.L. & Lee, R.T. 2004. Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein. J Biol Chem279, 30369-30374.
41. Seal, R.S., Wang, X., Guan, Y., Raja, S.N., Woodbury, C.J., Basbaum, A.I. & Edwards, R.H. 2009. Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors. Nature462, 651-655.
42. Stomatoyannopoulos, G., Chen, S.H. & Fukui, M. 1975. Liver alcohol dehydrogenase in Japanese: high population frequency of atypical form and its possible role in alcohol sensitivity. Am J Human Genet27, 789-796.
43. Story, G.M., Peier, A.M., Reeve, A.J., Eid, S.R., Mosbacher, J., Hricik, T.R., Earley, T.J., Hergarden, A.C., Andersson, D.A., Hwang, S.W., McIntyre, P., Jegla, T., Bevan, S. & Patapoutian, A. 2003. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell112, 819-829.
44. Suzuki, Y., Sato, J., Kawanishi, M. & Mizumura, K. 2002. Tissue glucose modulates the mechanical responses of cutaneous nociceptors in streptozotocin-diabetic rats but not normal rats in vitro. Pain99, 475-484.
45. Takahashi, N., Mizuno, Y., Kozai, D., Yamamoto, S., Kiyonaka, S., Shibata, T., Uchida, K. & Mori, Y. 2008. Molecular characterization of TRPA1 channel activation by cysteine reactive inflammatory mediators. Channels2, 1-12.
46. Tang, T.S., Prior, S.L., Li, K.W., Ireland, H.A., Bain, S.C., Hurel, S.J., Cooper, J.A., Humphries, S.E. & Stephens, J.W. 2011. Association between the rs1050450 glutathione preoxidase-1 (C > T) gene variant and peripheral neuropathy in two independent samples of subject with diabetes mellitus. Nutr, Metab & Cardiovasc Dis doi:10.1016/j.numecd.2010.08.001.
47. Taylor-Clark, T.E., Undem, B.J., MacGlashan, D.W., Ghatta, S., Carr, M.J. & McAlexander, M.A. 2008. Prostaglandin-induced activation of nociceptive neurons via direct interaction with transient receptor potential A1 (TRPA1). Mol Pharmacol73, 274-281.
48. Tesfaye, S. 2007. Clinical features of diabetic polyneuropathy. In: A. Veves & R.A. Malik (eds) Diabetic Neuropathy Clinical Management 2nd Edition, 243-257. Humana Press, Totowa, NJ.
49. Torsney, C. 2011. Inflammatory pain unmasks heterosynaptic facilitation in lamina I neurokinin 1 receptor-expressing neurons in rat spinal cord. J Neurosci31, 5158-5168.
50. Traverso, N., Menini, S., Odetti, P., Pronzato, M.A., Cottalasso, D. & Marinari, U.M. 2002. Diabetes impairs the enzymatic disposal of 4-hydroxynonenal in rat liver. Free Radical Biol & Med32, 350-359.
51. Trevisani, M., Siemens, J., Materazzi, S., Bautista, D.M., Nassini, R., Campi, B., Imamachi, N., Andre, E., Patacchini, R., Cottrell, G.S., Gatti, R., Basbaum, A.I., Bunnett, N.W., Julius, D. & Geppetti, P. 2007. 4-hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1. Proc Natl Acad Sci USA104, 13519-13524.
52. Wang, Y.Y., Chang, R.B., Waters, H.N., McKemy, D.D. & Liman, E.R. 2008. The nociceptor ion channels TRPA1 is potentiated and inactivated by permeating calcium ions. J Biol Chem283, 32691-32703.
53. Wei, H., Hämäläinen, M., Saarnilehto, M., Koivisto, A. & Pertovaara, A. 2009. Attenuation of mechanical hypersensitivity by an antagonist of the TRPA1 ion channels in diabetic animals. Anesthesiology111, 147-154.
54. Wei, H., Chapman, H., Saarnilehto, M., Kuokkanen, K., Koivisto, A. & Pertovaara, A. 2010a. Roles of cutaneous versus spinal TRPA1 channels in mechanical hypersensitivity in the diabetic or mustard oil-treated non-diabetic rat. Neuropharmacology58, 578-584.
55. Wei, H., Koivisto, A. & Pertovaara, A. 2010b. Spinal TRPA1 ion channel contribute to cutaneous neurogenic inflammation in the rat. Neurosci Lett479, 253-256.
56. Wei, H., Koivisto, A., Saarnilehto, M., Chapman, H., Kuokkanen, K., Hao, B., Huang, J.-L., Wang, Y.-X. & Pertovaara, A. 2011. Spinal transient receptor potential ankyrin 1 channel contributes to central pain hypersensitivity in various pathophysiological conditions in the rat. Pain152, 582-591.
57. Xiao, B., Dubin, A.E., Bursulaya, B., Viswanath, V., Jaegla, T.J. & Patapoutian, A. 2008. Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels. J Neurosci28, 9640-9651.
58. 2+. Nat Neurosci10, 277-279.