Arabidopsis β1,2-xylosyltransferase: Substrate specificity and participation in the plant-specific N-glycosylation pathway

Journal of Bioscience and Bioengineering

Volumn 113, Issue 1, 2012, Pages 48-54

  Kajiura, Hiroyuki ^a   Okamoto, Toru ^b,c   Misaki, Ryo ^a   Matsuura, Yoshiharu ^b   Fujiyama, Kazuhito ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

1,2 Xylosylation; Arabidopsis 1,2 Xylosyltransferase; Baculovirus; N glycan; Plant N glycosylation

Indexed keywords

ARABIDOPSIS; BACULOVIRUS; CHITOBIOSE; GAIN INSIGHT; GLYCOSYL TRANSFERASE; INSECT CELLS; MANNOSIDASE; N-ACETYLGLUCOSAMINE; N-GLYCAN; N-GLYCANS; N-GLYCOSYLATION; SUBSTRATE SPECIFICITY; WILD TYPES;

ESTERIFICATION; GLYCOSYLATION; MAMMALS;

SUBSTRATES;

2 AMINOPYRIDINE DERIVATIVE; ALPHA 1,3 FUCOSYLTRANSFERASE; ARABIDOPSIS BETA 1,2 XYLOSYLTRANSFERASE; ARABIDOPSIS PROTEIN; CHITOBIOSE; FUCOSE; GALACTOSE; GLYCAN DERIVATIVE; MANNOSE; MANNOSIDASE; N ACETYLGLUCOSAMINE; RECOMBINANT PROTEIN; TRANSFERASE; UNCLASSIFIED DRUG;

ARABIDOPSIS; ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; HETEROLOGOUS EXPRESSION; INSECT CELL; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION;

ACETYLGLUCOSAMINE; ANIMALS; ARABIDOPSIS; ARABIDOPSIS PROTEINS; CARBOHYDRATE SEQUENCE; FUCOSE; GALACTOSE; GLYCOSYLATION; INSECTS; MANNOSE; PENTOSYLTRANSFERASES; POLYSACCHARIDES; SUBSTRATE SPECIFICITY; XYLOSE;

ARABIDOPSIS; HEXAPODA; MAMMALIA;

EID: 84855352091     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2011.09.011     Document Type: Article

References (27)

1. Helenius A., Aebi M. Intracellular function of N-linked glycans. Science 2001, 291:2364-2369.
2. Varki A. Biological roles of oligosaccharides: all of the theories are correct. Glycobiology 1993, 3:97-130.
3. Helenius A., Aebi M. Roles of N-linked glycans in the endoplasmic reticulum. Annu. Rev. Biochem. 2004, 73:19-49.
4. Kornfeld R., Kornfeld S. Assembly of asparagine-linked oligosaccharides. Annu. Rev. Biochem. 1985, 54:631-664.
5. Strasser R., Mucha J., Mach L., Altmann F., Wilson I.B., Glössl J., Steinkellner H. Molecular cloning and functional expression of β1, 2-xylosyltransferase cDNA from Arabidopsis thaliana. FEBS Lett. 2000, 472:105-108.
6. Wilson I.B., Rendic D., Freilinger A., Dumic J., Altmann F., Mucha J., Muller S., Hauser M.T. Cloning and expression of cDNAs encoding α1,3-fucosyltransferase homologues from Arabidopsis thaliana. Biochim. Biophys. Acta 2001, 1527:88-96.
7. Bondili J.S., Castilho A., Mach L., Glossl J., Steinkellner H., Altmann F., Strasser R. Molecular cloning and heterologous expression of β1,2-xylosyltransferase and core α1,3-fucosyltransferase from maize. Phytochemistry 2006, 67:2215-2224.
8. Strasser R., Bondili J.S., Vavra U., Schoberer J., Svoboda B., Glössl J., Léonard R., Stadlmann J., Altmann F., Steinkellner H., Mach L. A unique β1,3-galactosyltransferase is indispensable for the biosynthesis of N-glycans containing Lewis a structures in Arabidopsis thaliana. Plant Cell 2007, 19:2278-2292.
9. Bencúr P., Steinkellner H., Svoboda B., Mucha J., Strasser R., Kolarich D., Hann S., Köllensperger G., Glössl J., Altmann F., Mach L. Arabidopsis thaliana β1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway. Biochem. J. 2005, 388:515-525.
10. Sourrouille C., Marquet-Blouin E., D'Aoust M.A., Kiefer-Meyer M.C., Seveno M., Pagny-Salehabadi S., Bardor M., Durambur G., Lerouge P., Vezina L., Gomord V. Down-regulated expression of plant-specific glycoepitopes in alfalfa. Plant Biotechnol. J. 2008, 6:702-721.
11. Pagny S., Bouissonnie F., Sarkar M., Follet-Gueye M.L., Driouich A., Schachter H., Faye L., Gomord V. Structural requirements for Arabidopsis β1,2-xylosyltransferase activity and targeting to the Golgi. Plant J. 2003, 33:189-203.
12. van Ree R., Cabanes-Macheteau M., Akkerdaas J., Milazzo J.P., Loutelier-Bourhis C., Rayon C., Villalba M., Koppelman S., Aalberse R., Rodriguez R., Faye L., Lerouge P. β(1,2)-Xylose and α(1,3)-fucose residues have a strong contribution in IgE binding to plant glycoallergens. J. Biol. Chem. 2000, 275:11451-11458.
13. Altmann F. The role of protein glycosylation in allergy. Int. Arch. Allergy Immunol. 2007, 142:99-115.
14. Palacpac N.Q., Yoshida S., Sakai H., Kimura Y., Fujiyama K., Yoshida T., Seki T. Stable expression of human β1,4-galactosyltransferase in plant cells modifies N-linked glycosylation patterns. Proc. Natl. Acad. Sci. USA 1999, 96:4692-4697.
15. Misaki R., Kimura Y., Fujiyama K., Seki T. Glycoproteins secreted from suspension-cultured tobacco BY2 cells have distinct glycan structures from intracellular glycoproteins. Biosci. Biotechnol. Biochem. 2001, 65:2482-2488.
16. Kajiura H., Seki T., Fujiyama K. Arabidopsis thaliana ALG3 mutant synthesizes immature oligosaccharides in the ER and accumulates unique N-glycans. Glycobiology 2010, 20:736-751.
17. Paroutis P., Touret N., Grinstein S. The pH of the secretory pathway: measurement, determinants, and regulation. Physiology 2004, 19:207-215.
18. Strasser R., Schoberer J., Jin C., Glössl J., Mach L., Steinkellner H. Molecular cloning and characterization of Arabidopsis thaliana Golgi α-mannosidase II, a key enzyme in the formation of complex N-glycans in plants. Plant J. 2006, 45:789-803.
19. Kaulfuerst-Soboll H., Rips S., Koiwa H., Kajiura H., Fujiyama K., von Schaewen A. Reduced immunogenicity of Arabidopsis hybrid glycosylation1 (hgl1) N-glycans due to altered accessibility of xylose and core fucose epitopes. J. Biol. Chem. 2011, 286:22955-22964.
20. Gomord V., Fitchette A.C., Menu-Bouaouiche L., Saint-Jore-Dupas C., Plasson C., Michaud D., Faye L. Plant-specific glycosylation patterns in the context of therapeutic protein production. Plant Biotechnol. J. 2010, 8:564-587.
21. Saint-Jore-Dupas C., Nebenführ A., Boulaflous A., Follet-Gueye M.L., Plasson C., Hawes C., Driouich A., Faye L., Gomord V. Plant N-glycan processing enzymes employ different targeting mechanisms for their spatial arrangement along the secretory pathway. Plant Cell 2006, 18:3182-3200.
22. Kang J.S., Frank J., Kang C.H., Kajiura H., Vikram M., Ueda A., Kim S., Bahk J.D., Triplett B., Fujiyama K., Lee S.Y., von Schaewen A., Koiwa H. Salt tolerance of Arabidopsis thaliana requires maturation of N-glycosylated proteins in the Golgi apparatus. Proc. Natl. Acad. Sci. USA 2008, 105:5933-5938.
23. von Schaewen A., Sturm A., O'Neill J., Chrispeels M.J. Isolation of a mutant Arabidopsis plant that lacks N-acetyl glucosaminyl transferase I and is unable to synthesize Golgi-modified complex N-linked glycans. Plant Physiol. 1993, 102:1109-1118.
24. Strasser R., Altmann F., Mach L., Glössl J., Steinkellner H. Generation of Arabidopsis thaliana plants with complex N-glycans lacking beta1,2-linked xylose and core alpha1,3-linked fucose. FEBS Lett. 2004, 561:132-136.
25. Huang J., Sutliff T.D., Wu L., Nandi S., Benge K., Terashima M., Ralston A.H., Drohan W., Huang N., Rodriguez R.L. Expression and purification of functional human r-1-antitrypsin from cultured plant cells. Biotechnol. Prog. 2001, 17:126-133.
26. Bakker H., Rouwendal G.J., Karnoup A.S., Florack D.E., Stoopen G.M., Helsper J.P., van Ree R., van Die I., Bosch D. An antibody produced in tobacco expressing a hybrid β-1,4-galactosyltransferase is essentially devoid of plant carbohydrate epitopes. Proc. Natl. Acad. Sci. USA 2006, 103:7577-7582.
27. Vézina L.P., Faye L., Lerouge P., D'Aoust M.A., Marquet-Blouin E., Burel C., Lavoie P.O., Bardor M., Gomord V. Transient co-expression for fast and high-yield production of antibodies with human-like N-glycans in plant. Plant Biotechnol. J. 2009, 7:442-455.