메뉴 건너뛰기




Volumn 81, Issue SUPPL. 1, 2011, Pages 50-55

Adjuvant therapy after curative treatment for hepatocellular carcinoma

Author keywords

Adjuvant therapy; Curative treatment; Hepatocellular carcinoma; Improvement of survival; Interferon molecular targeted agents; Prevention of recurrence

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PEGINTERFERON; PEGINTERFERON ALPHA2A; PERETINOIN; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; RAF PROTEIN; RIBAVIRIN; SORAFENIB; VASCULAR ENDOTHELIAL GROWTH INHIBITOR; VITAMIN K GROUP;

EID: 84855323080     PISSN: 00302414     EISSN: 14230232     Source Type: Journal    
DOI: 10.1159/000333259     Document Type: Review
Times cited : (46)

References (36)
  • 1
    • 0036271549 scopus 로고    scopus 로고
    • Randomized clinical trial of long-term outcome after resection of hepatitis C virus-related hepatocellular carcinoma by postoperative interferon therapy
    • DOI 10.1046/j.0007-1323.2001.02054.x
    • Kubo S, Nishiguchi S, Hirohashi K, Tanaka H, Shuto T, Kinoshita H: Randomized clinical trial of long-term outcome after resection of hepatitis C virus-related hepatocellular carcinoma by postoperative interferon therapy. Br J Surg 2002;89:418-422. (Pubitemid 34595504)
    • (2002) British Journal of Surgery , vol.89 , Issue.4 , pp. 418-422
    • Kubo, S.1    Nishiguchi, S.2    Hirohashi, K.3    Tanaka, H.4    Shuto, T.5    Kinoshita, H.6
  • 2
    • 0033854015 scopus 로고    scopus 로고
    • Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor - A prospective randomized study of hepatitis C virus - Related liver cancer
    • Ikeda K, Arase Y, Saitoh S, Kobayashi M, Suzuki Y, Suzuki F, et al.: Interferon beta prevents recurrence of hepatocellular carcinoma after complete resection or ablation of the primary tumor-A prospective randomized study of hepatitis C virus-related liver cancer. Hepatology 2000;32:228-232. (Pubitemid 30614654)
    • (2000) Hepatology , vol.32 , Issue.2 , pp. 228-232
    • Ikeda, K.1    Arase, Y.2    Saitoh, S.3    Kobayashi, M.4    Suzuki, Y.5    Suzuki, F.6    Tsubota, A.7    Chayama, K.8    Murashima, N.9    Kumada, H.10
  • 6
    • 0346093899 scopus 로고    scopus 로고
    • Prospective randomized controlled study of interferon-alpha in preventing hepatocellular carcinoma recurrence after medical ablation therapy for primary tumors
    • Lin SM, Lin CJ, Hsu CW, Tai DI, Sheen IS, Lin DY, et al.: Prospective randomized controlled study of interferon-alpha in preventing hepatocellular carcinoma recurrence after medical ablation therapy for primary tumors. Cancer 2004;100:376-382.
    • (2004) Cancer , vol.100 , pp. 376-382
    • Lin, S.M.1    Lin, C.J.2    Hsu, C.W.3    Tai, D.I.4    Sheen, I.S.5    Lin, D.Y.6
  • 7
    • 34249316548 scopus 로고    scopus 로고
    • A randomized, controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma
    • DOI 10.1097/01.sla.0000245829.00977.45, PII 0000065820070600000001
    • Lo CM, Liu CL, Chan SC, Lam CM, Poon RT, Ng IO, et al.: A randomized, controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma. Ann Surg 2007;245:831-842. (Pubitemid 46809282)
    • (2007) Annals of Surgery , vol.245 , Issue.6 , pp. 831-842
    • Lo, C.M.1    Liu, C.L.2    Chan, S.C.3    Lam, C.M.4    Poon, R.T.P.5    Ng, I.O.L.6    Fan, S.T.7    Wong, J.8
  • 8
    • 33646736379 scopus 로고    scopus 로고
    • Postoperative interferon alpha treatment postponed recurrence and improved overall survival in patients after curative resection of HBV-related hepatocellular carcinoma: A randomized clinical trial
    • Sun HC, Tang ZY, Wang L, Qin LX, Ma ZC, Ye QH, et al.: Postoperative interferon alpha treatment postponed recurrence and improved overall survival in patients after curative resection of HBV-related hepatocellular carcinoma: a randomized clinical trial. J Cancer Res Clin Oncol 2006;132:458-465.
    • (2006) J Cancer Res Clin Oncol , vol.132 , pp. 458-465
    • Sun, H.C.1    Tang, Z.Y.2    Wang, L.3    Qin, L.X.4    Ma, Z.C.5    Ye, Q.H.6
  • 9
    • 79952316752 scopus 로고    scopus 로고
    • Maintenance peginterferon therapy and other factors associated with hepatocellular carcinoma in patients with advanced hepatitis C
    • quiz e12
    • Lok AS, Everhart JE, Wright EC, Di Bisceglie AM, Kim HY, Sterling RK, et al.: Maintenance peginterferon therapy and other factors associated with hepatocellular carcinoma in patients with advanced hepatitis C. Gastroenterology 2011;140:840-849, quiz e12.
    • (2011) Gastroenterology , vol.140 , pp. 840-849
    • Lok, A.S.1    Everhart, J.E.2    Wright, E.C.3    Di Bisceglie, A.M.4    Kim, H.Y.5    Sterling, R.K.6
  • 10
    • 37149036135 scopus 로고    scopus 로고
    • Long-term interferon maintenance therapy improves survival in patients with HCV-related hepatocellular carcinoma after curative radiofrequency ablation: A matched case-control study
    • Kudo M, Sakaguchi Y, Chung H, Hatanaka K, Hagiwara S, Ishikawa E, et al.: Long-term interferon maintenance therapy improves survival in patients with HCV-related hepatocellular carcinoma after curative radiofrequency ablation: a matched case-control study. Oncology 2007;72:S132-S138.
    • (2007) Oncology , vol.72
    • Kudo, M.1    Sakaguchi, Y.2    Chung, H.3    Hatanaka, K.4    Hagiwara, S.5    Ishikawa, E.6
  • 12
    • 17244379463 scopus 로고    scopus 로고
    • Low-dose, long-term, intermittent interferon-alpha-2b therapy after radical treatment by radiofrequency ablation delays clinical recurrence in patients with hepatitis C virus-related hepatocellular carcinoma
    • DOI 10.1159/000082097
    • Sakaguchi Y, Kudo M, Fukunaga T, Minami Y, Chung H, Kawasaki T: Low-dose, longterm, intermittent interferon-alpha-2b therapy after radical treatment by radiofrequency ablation delays clinical recurrence in patients with hepatitis C virus-related hepatocellular carcinoma. Intervirology 2005;48:64-70. (Pubitemid 40529213)
    • (2005) Intervirology , vol.48 , Issue.1 , pp. 64-70
    • Sakaguchi, Y.1    Kudo, M.2    Fukunaga, T.3    Minami, Y.4    Chung, H.5    Kawasaki, T.6
  • 13
    • 33644693596 scopus 로고    scopus 로고
    • Antiviral therapy after non-surgical tumor ablation in patients with hepatocellular carcinoma associated with hepatitis C virus
    • DOI 10.1111/j.1440-1746.2005.03925.x
    • Hung CH, Lee CM, Wang JH, Tung HD, Chen CH, Lu SN: Antiviral therapy after non-surgical tumor ablation in patients with hepatocellular carcinoma associated with hepatitis C virus. J Gastroenterol Hepatol 2005;20:1553-1559. (Pubitemid 43961110)
    • (2005) Journal of Gastroenterology and Hepatology , vol.20 , Issue.10 , pp. 1553-1559
    • Hung, C.-H.1    Lee, C.-M.2    Wang, J.-H.3    Tung, H.-D.4    Chen, C.-H.5    Lu, S.-N.6
  • 15
    • 33947577080 scopus 로고    scopus 로고
    • Interferon lowers tumor recurrence rate after surgical resection or ablation of hepatocellular carcinoma: A pilot study of patients with hepatitis B virus-related cirrhosis
    • DOI 10.1007/s00535-006-1912-0
    • Someya T, Ikeda K, Saitoh S, Kobayashi M, Hosaka T, Sezaki H, et al.: Interferon lowers tumor recurrence rate after surgical resection or ablation of hepatocellular carcinoma: a pilot study of patients with hepatitis B virus- related cirrhosis. J Gastroenterol 2006;41:1206-1213. (Pubitemid 46487211)
    • (2006) Journal of Gastroenterology , vol.41 , Issue.12 , pp. 1206-1213
    • Someya, T.1    Ikeda, K.2    Saitoh, S.3    Kobayashi, M.4    Hosaka, T.5    Sezaki, H.6    Akuta, N.7    Suzuki, F.8    Suzuki, Y.9    Arase, Y.10    Kumada, H.11
  • 17
    • 78649655583 scopus 로고    scopus 로고
    • Interferon- alpha therapy after curative resection prevents early recurrence and improves survival in patients with hepatitis B virus-related hepatocellular carcinoma
    • Qu LS, Jin F, Huang XW, Shen XZ: Interferon- alpha therapy after curative resection prevents early recurrence and improves survival in patients with hepatitis B virus-related hepatocellular carcinoma. J Surg Oncol 2010;102:796-801.
    • (2010) J Surg Oncol , vol.102 , pp. 796-801
    • Qu, L.S.1    Jin, F.2    Huang, X.W.3    Shen, X.Z.4
  • 18
    • 78649854047 scopus 로고    scopus 로고
    • Administration of interferon for two or more years decreases early stage hepatocellular carcinoma recurrence rate after radical ablation: A retrospective study of hepatitis C virus-related liver cancer
    • Ikeda K, Kobayashi M, Seko Y, Imai N, Hirakawa M, Kawamura Y, et al.: Administration of interferon for two or more years decreases early stage hepatocellular carcinoma recurrence rate after radical ablation: a retrospective study of hepatitis C virus-related liver cancer. Hepatol Res 2010;40:1168-1175.
    • (2010) Hepatol Res , vol.40 , pp. 1168-1175
    • Ikeda, K.1    Kobayashi, M.2    Seko, Y.3    Imai, N.4    Hirakawa, M.5    Kawamura, Y.6
  • 19
    • 58149104341 scopus 로고    scopus 로고
    • Impact of interferon therapy after curative treatment of hepatocellular carcinoma
    • Kudo M: Impact of interferon therapy after curative treatment of hepatocellular carcinoma. Oncology 2008;75(suppl 1):30-41.
    • (2008) Oncology , vol.75 , Issue.SUPPL. 1 , pp. 30-41
    • Kudo, M.1
  • 20
    • 63449138556 scopus 로고    scopus 로고
    • Secondary prevention of recurrence by interferon therapy after ablation therapy for hepatocellular carcinoma in chronic hepatitis C patients
    • Ishikawa T: Secondary prevention of recurrence by interferon therapy after ablation therapy for hepatocellular carcinoma in chronic hepatitis C patients. World J Gastroenterol 2008;14:6140-6144.
    • (2008) World J Gastroenterol , vol.14 , pp. 6140-6144
    • Ishikawa, T.1
  • 21
    • 77954266287 scopus 로고    scopus 로고
    • Postoperative adjuvant antiviral therapy for hepatitis B/C virus-related hepatocellular carcinoma: A meta-analysis
    • Miao RY, Zhao HT, Yang HY, Mao YL, Lu X, Zhao Y, et al.: Postoperative adjuvant antiviral therapy for hepatitis B/C virus-related hepatocellular carcinoma: a meta-analysis. World J Gastroenterol 2010;16:2931-2942.
    • (2010) World J Gastroenterol , vol.16 , pp. 2931-2942
    • Miao, R.Y.1    Zhao, H.T.2    Yang, H.Y.3    Mao, Y.L.4    Lu, X.5    Zhao, Y.6
  • 22
    • 77950220516 scopus 로고    scopus 로고
    • Meta-analysis: Interferon-alpha prevents the recurrence after curative treatment of hepatitis C virus-related hepatocellular carcinoma
    • Miyake Y, Takaki A, Iwasaki Y, Yamamoto K: Meta-analysis: interferon-alpha prevents the recurrence after curative treatment of hepatitis C virus-related hepatocellular carcinoma. J Viral Hepat 2010;17:287-292.
    • (2010) J Viral Hepat , vol.17 , pp. 287-292
    • Miyake, Y.1    Takaki, A.2    Iwasaki, Y.3    Yamamoto, K.4
  • 23
    • 69249110100 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of interferon after curative treatment of hepatocellular carcinoma in patients with viral hepatitis
    • Breitenstein S, Dimitroulis D, Petrowsky H, Puhan MA, Mullhaupt B, Clavien PA: Systematic review and meta-analysis of interferon after curative treatment of hepatocellular carcinoma in patients with viral hepatitis. Br J Surg 2009;96:975-981.
    • (2009) Br J Surg , vol.96 , pp. 975-981
    • Breitenstein, S.1    Dimitroulis, D.2    Petrowsky, H.3    Puhan, M.A.4    Mullhaupt, B.5    Clavien, P.A.6
  • 24
    • 65649140040 scopus 로고    scopus 로고
    • Effects of interferon alpha treatment on recurrence and survival after complete resection or ablation of hepatocellular carcinoma: A metaanalysis of randomized controlled trials
    • Zhang CH, Xu GL, Jia WD, Ge YS: Effects of interferon alpha treatment on recurrence and survival after complete resection or ablation of hepatocellular carcinoma: a metaanalysis of randomized controlled trials. Int J Cancer 2009;124:2982-2988.
    • (2009) Int J Cancer , vol.124 , pp. 2982-2988
    • Zhang, C.H.1    Xu, G.L.2    Jia, W.D.3    Ge, Y.S.4
  • 25
    • 77952422635 scopus 로고    scopus 로고
    • Adjuvant interferon therapy after curative therapy for hepatocellular carcinoma (HCC): A meta-regression approach
    • Shen YC, Hsu C, Chen LT, Cheng CC, Hu FC, Cheng AL: Adjuvant interferon therapy after curative therapy for hepatocellular carcinoma (HCC): a meta-regression approach. J Hepatol 2010;52:889-894.
    • (2010) J Hepatol , vol.52 , pp. 889-894
    • Shen, Y.C.1    Hsu, C.2    Chen, L.T.3    Cheng, C.C.4    Hu, F.C.5    Cheng, A.L.6
  • 26
    • 77956397191 scopus 로고    scopus 로고
    • Meta-analysis: Interferon improves outcomes following ablation or resection of hepatocellular carcinoma
    • Singal AK, Freeman DH Jr, Anand BS: Meta-analysis: interferon improves outcomes following ablation or resection of hepatocellular carcinoma. Aliment Pharmacol Ther 2010;32:851-858.
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 851-858
    • Singal, A.K.1    Freeman Jr., D.H.2    Anand, B.S.3
  • 27
    • 77954504346 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma: Report of Consensus Meeting in the 45th Annual Meeting of the Japan Society of Hepatology (2009)
    • Arii S, Sata M, Sakamoto M, Shimada M, Kumada T, Shiina S, et al.: Management of hepatocellular carcinoma: Report of Consensus Meeting in the 45th Annual Meeting of the Japan Society of Hepatology (2009). Hepatol Res 2010;40:667-685.
    • (2010) Hepatol Res , vol.40 , pp. 667-685
    • Arii, S.1    Sata, M.2    Sakamoto, M.3    Shimada, M.4    Kumada, T.5    Shiina, S.6
  • 28
    • 84984586846 scopus 로고    scopus 로고
    • Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma
    • Omata M, Lesmana L, Tateishi R, Chen P, Lin S, Yoshida H, et al.: Asian Pacific Association for the Study of the Liver consensus recommendations on hepatocellular carcinoma. Hepatol Int 2010;4:439-474.
    • (2010) Hepatol Int , vol.4 , pp. 439-474
    • Omata, M.1    Lesmana, L.2    Tateishi, R.3    Chen, P.4    Lin, S.5    Yoshida, H.6
  • 30
    • 57749189578 scopus 로고    scopus 로고
    • Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
    • Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, Kim JS, et al.: Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009;10:25-34.
    • (2009) Lancet Oncol , vol.10 , pp. 25-34
    • Cheng, A.L.1    Kang, Y.K.2    Chen, Z.3    Tsao, C.J.4    Qin, S.5    Kim, J.S.6
  • 31
    • 77955715213 scopus 로고    scopus 로고
    • Current status of molecularly targeted therapy for hepatocellular carcinoma: Clinical practice
    • Kudo M: Current status of molecularly targeted therapy for hepatocellular carcinoma: clinical practice. Int J Clin Oncol 2010;15:242-255.
    • (2010) Int J Clin Oncol , vol.15 , pp. 242-255
    • Kudo, M.1
  • 32
    • 80051758429 scopus 로고    scopus 로고
    • Management of hepatocellular carcinoma in Japan: Consensus-Based Clinical Practice Guideline proposed by the Japan Society of Hepatology (JSH) 2010 updated version
    • Kudo M, Izumi N, Kokudo N, Matsui O, Sakamoto M, Nakashima O, et al.: Management of hepatocellular carcinoma in Japan: Consensus-Based Clinical Practice Guideline proposed by the Japan Society of Hepatology (JSH) 2010 updated version. Dig Dis 2011;29:339-364.
    • (2011) Dig Dis , vol.29 , pp. 339-364
    • Kudo, M.1    Izumi, N.2    Kokudo, N.3    Matsui, O.4    Sakamoto, M.5    Nakashima, O.6
  • 34
    • 0033118925 scopus 로고    scopus 로고
    • Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma [4]
    • DOI 10.1056/NEJM199904013401315
    • Muto Y, Moriwaki H, Saito A: Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma. N Engl J Med 1999;340: 1046-1047. (Pubitemid 29157643)
    • (1999) New England Journal of Medicine , vol.340 , Issue.13 , pp. 1046-1047
    • Muto, Y.1    Moriwaki, H.2    Saito, A.3
  • 35
    • 0035253469 scopus 로고    scopus 로고
    • Des-gamma-carboxy prothrombin as a useful predisposing factor for the development of portal venous invasion in patients with hepatocellular carcinoma: A prospective analysis of 227 patients
    • DOI 10.1002/1097-0142(20010201)91:3<561::AID-CNCR1035>3.0.CO;2-N
    • Koike Y, Shiratori Y, Sato S, Obi S, Teratani T, Imamura M, et al.: Des-gamma-carboxy prothrombin as a useful predisposing factor for the development of portal venous invasion in patients with hepatocellular carcinoma: a prospective analysis of 227 patients. Cancer 2001;91: 561-569. (Pubitemid 32105702)
    • (2001) Cancer , vol.91 , Issue.3 , pp. 561-569
    • Koike, Y.1    Shiratori, Y.2    Sato, S.3    Obi, S.4    Teratani, T.5    Imamura, M.6    Yoshida, H.7    Shiina, S.8    Omata, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.