Chikungunya virus neutralization antigens and direct cell-to-cell transmission are revealed by human antibody-escape mutants

PLoS Pathogens

Volumn 7, Issue 12, 2011, Pages

  Lee, Chia Yin ^a   Kam, Yiu Wing ^a   Fric, Jan ^a   Malleret, Benoit ^a   Koh, Esther G L ^a   Prakash, Celine ^a   Huang, Wen ^a   Lee, Wendy W L ^a   Lin, Cui ^b   Lin, Raymond T P ^b,c   Renia, Laurent ^a   Wang, Cheng I ^a   Ng, Lisa F P ^a,c   Warter, Lucile ^a  

^a AGENCY FOR SCIENCE   (Singapore)

^b MINISTRY OF HEALTH   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

NEUTRALIZING ANTIBODY; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS PROTEIN;

ARTICLE; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; NONHUMAN; VIRUS CELL INTERACTION; VIRUS MUTATION; VIRUS NEUTRALIZATION; VIRUS RESISTANCE; VIRUS TRANSMISSION; ALPHAVIRUS INFECTION; ANIMAL; CELL STRAIN HEK293; CHRONIC DISEASE; DISEASE TRANSMISSION; GENETICS; HUMAN; IMMUNE EVASION; IMMUNOLOGY; MOUSE; MOUSE MUTANT; MUTATION; PATHOGENICITY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

ALPHAVIRUS; ANIMALIA; CHIKUNGUNYA VIRUS; PRIMATES;

ALPHAVIRUS INFECTIONS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CHIKUNGUNYA VIRUS; CHRONIC DISEASE; HEK293 CELLS; HUMANS; IMMUNE EVASION; IMMUNOGLOBULIN M; MICE; MICE, KNOCKOUT; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; VIRAL PROTEINS;

EID: 84855319039     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002390     Document Type: Article

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