Ecotoxicogenomics to support ecological risk assessment: A case study with bisphenol A in fish

Environmental Science and Technology

Volumn 46, Issue 1, 2012, Pages 51-59

  Villeneuve, Daniel L ^a   Garcia Reyero, Natàlia ^b   Escalon, B Lynn ^c   Jensen, Kathleen M ^a   Cavallin, Jenna E ^a   Makynen, Elizabeth A ^a   Durhan, Elizabeth J ^a   Kahl, Michael D ^a   Thomas, Linnea M ^a   Perkins, Edward J ^c   Ankley, Gerald T ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b JACKSON STATE UNIVERSITY   (United States)

^c US ARMY ENGINEER RESEARCH AND DEVELOPMENT CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHENOL A; COMPARATIVE DATA; DANIO RERIO; DIFFERENTIALLY EXPRESSED GENE; ECOLOGICAL RISK ASSESSMENT; ECOTOXICOGENOMICS; END POINTS; FATHEAD MINNOW; FISH SPECIES; NONMONOTONIC; PIMEPHALES PROMELAS; POTENTIAL APPLICATIONS; TO EFFECT; TRANSCRIPTOMES; VITELLOGENIN; WATERBORNE EXPOSURE; ZEBRAFISH;

ECOLOGY; FISH; GENE EXPRESSION; PHENOLS;

RISK ASSESSMENT;

4,4' ISOPROPYLIDENEDIPHENOL; STEROID; VITELLOGENIN;

CONCENTRATION (COMPOSITION); CYPRINID; DATA SET; ECOTOXICOLOGY; ENDOCRINE DISRUPTOR; ENVIRONMENTAL ASSESSMENT; ENVIRONMENTAL RISK; GENE EXPRESSION; GENOMICS; PHENOL; PHYSIOLOGICAL RESPONSE; RISK ASSESSMENT;

ARTICLE; CHEMICAL MODIFICATION; CHOLESTEROL TRANSPORT; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE; ECOLOGY; ECOTOXICOLOGY; EX VIVO STUDY; FEMALE; FISH; GENE EXPRESSION; HYPOPHYSIS GONAD SYSTEM; MALE; NONHUMAN; PIMEPHALES PROMELAS; PRINCIPAL COMPONENT ANALYSIS; RISK ASSESSMENT; STEROIDOGENESIS; ZEBRA FISH;

ANIMALS; CYPRINIDAE; ECOTOXICOLOGY; FEMALE; GENE EXPRESSION REGULATION; MALE; METAGENOMICS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOLS; PRINCIPAL COMPONENT ANALYSIS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; TOXICITY TESTS; TRANSCRIPTOME; VITELLOGENINS; ZEBRAFISH;

DANIO RERIO; PIMEPHALES PROMELAS;

EID: 84855317623     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es201150a     Document Type: Article

References (28)

1. Committee on Toxicity Testing and Assessment of Environmental Agents, N. R. C. Toxicity Testing in the 21st Century: A Vision and a Strategy; National Academies Press: Washington, DC, 2007; p 216.
2. Lobenhofer, E. K.; Cui, X.; Bennett, L.; Cable, P. L.; Merrick, B. A.; Churchill, G. A.; Afshari, C. A. Exploration of low-dose estrogen effects: identification of No Observed Transcriptional Effect Level (NOTEL) Toxicol. Pathol. 2004, 32 (4) 482-92
3. Naciff, J. M.; Hess, K. A.; Overmann, G. J.; Torontali, S. M.; Carr, G. J.; Tiesman, J. P.; Foertsch, L. M.; Richardson, B. D.; Martinez, J. E.; Daston, G. P. Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A Toxicol. Sci. 2005, 86 (2) 396-416
4. Staples, C. A.; Dorn, P. B.; Klecka, G. M.; O'Block, S. T.; Harris, L. R. A review of the environmental fate, effects, and exposures of bisphenol A Chemosphere 1998, 36 (10) 2149-73
5. Klecka, G. M.; Staples, C. A.; Clark, K. E.; Van der Hoeven, N.; Thomas, D. E.; Hentges, S. G. Exposure analysis of bisphenol A in surface water systems in North America and Europe Environ. Sci. Technol. 2009, 43 (16) 6145-50
6. Bonefeld-Jorgensen, E. C.; Long, M.; Hofmeister, M. V.; Vinggaard, A. M. Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review Environ. Health Perspect. 2007, 115 (Suppl 1) 69-76
7. McMaster, M. E.; Jardine, M. K.; Robinson, J. J.; Van Der Kraak, R. D. GJ, Protocol for measuring in vitro steroid production by fish gonadal tissue Can. Tech. Rep. Fish. Aquat. Sci. 1995, 1961, 1-78
8. Villeneuve, D. L.; Mueller, N. D.; Martinovic, D.; Makynen, E. A.; Kahl, M. D.; Jensen, K. M.; Durhan, E. J.; Cavallin, J. E.; Bencic, D.; Ankley, G. T. Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor Environ. Health Perspect. 2009, 117 (4) 624-31
9. Korte, J. J.; Kahl, M. D.; Jensen, K. M.; Mumtaz, S. P.; Parks, L. G.; LeBlanc, G. A.; Ankley, G. T. Fathead minnow vitellogenin: complementary DNA sequence and messenger RNA and protein expression after 17B-estradiol treatment Environ. Toxicol. Chem. 2000, 19 (4) 972-981
10. Jensen, K.; Korte, J.; Kahl, M.; Pasha, M.; Ankley, G. Aspects of basic reproductive biology and endocrinology in the fathead minnow (Pimephales promelas) Comp. Biochem. Physiol., Part C: Pharmacol., Toxicol. Endocrinol. 2001, 128, 127-141
11. Ballman, K. V.; Grill, D. E.; Oberg, A. L.; Therneau, T. M. Faster cyclic loess: normalizing RNA arrays via linear models Bioinformatics 2004, 20 (16) 2778-86
12. Saeed, A. I.; Sharov, V.; White, J.; Li, J.; Liang, W.; Bhagabati, N.; Braisted, J.; Klapa, M.; Currier, T.; Thiagarajan, M.; Sturn, A.; Snuffin, M.; Rezantsev, A.; Popov, D.; Ryltsov, A.; Kostukovich, E.; Borisovsky, I.; Liu, Z.; Vinsavich, A.; Trush, V.; Quackenbush, J. TM4: a free, open-source system for microarray data management and analysis Biotechniques 2003, 34 (2) 374-8
13. Beisvag, V.; Junge, F. K.; Bergum, H.; Jolsum, L.; Lydersen, S.; Gunther, C. C.; Ramampiaro, H.; Langaas, M.; Sandvik, A. K.; Laegreid, A. GeneTools - application for functional annotation and statistical hypothesis testing BMC Bioinf. 2006, 7, 470
14. Huang, D.; Sherman, B.; Lempicki, R. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources Nat. Protoc. 2009, 4 (1) 44-57
15. Villeneuve, D. L.; Larkin, P.; Knoebl, I.; Miracle, A. L.; Kahl, M. D.; Jensen, K. M.; Makynen, E. A.; Durhan, E. J.; Carter, B. J.; Denslow, N. D.; Ankley, G. T. A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis Environ. Sci. Technol. 2007, 41 (1) 321-30
16. Wang, R. L.; Bencic, D.; Villeneuve, D. L.; Ankley, G. T.; Lazorchak, J.; Edwards, S. A transcriptomics-based biological framework for studying mechanisms of endocrine disruption in small fish species Aquat. Toxicol. 2011, 102, 232-235
17. Sohoni, P.; Tyler, C. R.; Hurd, K.; Caunter, J.; Hetheridge, M.; Williams, T.; Woods, C.; Evans, M.; Toy, R.; Gargas, M.; Sumpter, J. P. Reproductive effects of long-term exposure to Bisphenol A in the fathead minnow (Pimephales promelas) Environ. Sci. Technol. 2001, 35 (14) 2917-25
18. Van den Belt, K.; Verheyen, R.; Witters, H. Comparison of vitellogenin responses in zebrafish and rainbow trout following exposure to environmental estrogens Ecotoxicol. Environ. Saf. 2003, 56 (2) 271-81
19. Subramanian, A.; Tamayo, P.; Mootha, V. K.; Mukherjee, S.; Ebert, B. L.; Gillette, M. A.; Paulovich, A.; Pomeroy, S. L.; Golub, T. R.; Lander, E. S.; Mesirov, J. P. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles Proc. Natl. Acad. Sci. U. S. A. 2005, 102 (43) 15545-50
20. Xu, L. C.; Sun, H.; Chen, J. F.; Bian, Q.; Qian, J.; Song, L.; Wang, X. R. Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro Toxicology 2005, 216 (2-3) 197-203
21. Wetherill, Y. B.; Akingbemi, B. T.; Kanno, J.; McLachlan, J. A.; Nadal, A.; Sonnenschein, C.; Watson, C. S.; Zoeller, R. T.; Belcher, S. M. In vitro molecular mechanisms of bisphenol A action Reprod. Toxicol. 2007, 24 (2) 178-98
22. Pawitan, Y.; Michiels, S.; Koscielny, S.; Gusnanto, A.; Ploner, A. False discovery rate, sensitivity and sample size for microarray studies Bioinformatics 2005, 21 (13) 3017-24
23. Wright-Walters, M.; Volz, C.; Talbott, E.; Davis, D. An updated weight of evidence approach to the aquatic hazard assessment of Bisphenol A and the derivation a new predicted no effect concentration (Pnec) using a non-parametric methodology Sci. Total Environ. 2011, 409 (4) 676-85
24. Gou, N.; Onnis-Hayden, A.; Gu, A. Z. Mechanistic toxicity assessment of nanomaterials by whole-cell-array stress genes expression analysis Environ. Sci. Technol. 2010, 44 (15) 5964-70
25. Ankley, G. T.; Daston, G. P.; Degitz, S. J.; Denslow, N. D.; Hoke, R. A.; Kennedy, S. W.; Miracle, A. L.; Perkins, E. J.; Snape, J.; Tillitt, D. E.; Tyler, C. R.; Versteeg, D. Toxicogenomics in regulatory ecotoxicology Environ. Sci. Technol. 2006, 40 (13) 4055-65
26. Zarbl, H.; Gallo, M. A.; Glick, J.; Yeung, K. Y.; Vouros, P. The vanishing zero revisited: thresholds in the age of genomics Chem. Biol. Interact. 2010, 184 (1-2) 273-8
27. Poynton, H. C.; Loguinov, A. V.; Varshavsky, J. R.; Chan, S.; Perkins, E. J.; Vulpe, C. D. Gene expression profiling in Daphnia magna part I: concentration-dependent profiles provide support for the No Observed Transcriptional Effect Level Environ. Sci. Technol. 2008, 42 (16) 6250-6
28. Villeneuve, D. L.; Garcia-Reyero, N.; Martinovic, D.; Mueller, N. D.; Cavallin, J. E.; Durhan, E. J.; Makynen, E. A.; Jensen, K. M.; Kahl, M. D.; Blake, L. S.; Perkins, E. J.; Ankley, G. T. II: Effects of a dopamine receptor antagonist on fathead minnow dominance behavior and ovarian gene expression in the fathead minnow and zebrafish Ecotoxicol. Environ. Saf. 2010, 73 (4) 478-85