Cross-linked antioxidant nanozymes for improved delivery to CNS

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 8, Issue 1, 2012, Pages 119-129

  Klyachko, Natalia L ^a,b   Manickam, Devika S ^b   Brynskikh, Anna M ^b,c   Uglanova, Svetlana V ^a   Li, Shu ^b   Higginbotham, Sheila M ^b   Bronich, Tatiana K ^b   Batrakova, Elena V ^b   Kabanov, Alexander V ^a,b  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Brain delivery; Cross linking; Nanozymes; Polyion complexes

Indexed keywords

ANTIOXIDANT ENZYME; BRAIN DELIVERY; BRAIN TISSUE; CARBODIIMIDE HYDROCHLORIDES; CENTRAL NERVOUS SYSTEMS; CHARGE RATIO; COVALENT CROSSLINKING; CU/ZN-SOD; ELECTROSTATIC COUPLING; GEL ELECTROPHORESIS; GLUTARALDEHYDES; IN-VIVO; L-LYSINE; NANOZYMES; NEUROLOGICAL DISEASE; PHYSICO-CHEMICAL CHARACTERIZATION; POLYCATIONS; POLYION COMPLEX; REACTION CONDITIONS; SODIUM SALT; SUPER OXIDE DISMUTASE; WESTERN BLOTTING;

ALDEHYDES; AMINO ACIDS; ATOMIC FORCE MICROSCOPY; BLOCK COPOLYMERS; BLOOD; ELECTROPHORESIS; ENZYMES; ETHYLENE; GLYCOLS; NEURODEGENERATIVE DISEASES; OXYGEN; POLYETHYLENE GLYCOLS; TISSUE;

CROSSLINKING;

CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTARALDEHYDE; IODINE 125; MACROGOL; NANOPARTICLE;

ARTICLE; ATOMIC FORCE MICROSCOPY; BRAIN TISSUE; CENTRAL NERVOUS SYSTEM; CROSS LINKING; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME STABILITY; GEL ELECTROPHORESIS; NERVE CELL; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; WESTERN BLOTTING; ZETA POTENTIAL;

ANIMALS; ANTIOXIDANTS; BRAIN; CATALASE; CATTLE; CELL LINE; CENTRAL NERVOUS SYSTEM; DRUG DELIVERY SYSTEMS; ENZYME STABILITY; ENZYMES, IMMOBILIZED; GLUTARAL; IODINE RADIOISOTOPES; MALE; MICE; MICE, INBRED BALB C; MICROSCOPY, ATOMIC FORCE; NANOPARTICLES; NEURONS; OXIDATIVE STRESS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMERS; SUPEROXIDE DISMUTASE;

MUS;

EID: 84855309939     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2011.05.010     Document Type: Article

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