메뉴 건너뛰기




Volumn 16, Issue 1, 2012, Pages

Comparative evaluation of intratracheal colistimethate sodium, imipenem, and meropenem in BALB/c mice with carbapenem-resistant Acinetobacter baumannii pneumonia

Author keywords

Carbapenem resistant Acinetobacter baumannii; Colistin; Intratracheal; Meropenem; Mice; Pneumonia

Indexed keywords

CARBAPENEM; CILASTATIN; COLISTIMETHATE; CYTOKINE; IMIPENEM; MEROPENEM; MUCIN;

EID: 84855302139     PISSN: 12019712     EISSN: 18783511     Source Type: Journal    
DOI: 10.1016/j.ijid.2011.09.015     Document Type: Article
Times cited : (10)

References (46)
  • 1
    • 0031904174 scopus 로고    scopus 로고
    • Clinical problems posed by multiresistant nonfermenting Gram-negative pathogens
    • Quinn J.P. Clinical problems posed by multiresistant nonfermenting Gram-negative pathogens. Clin Infect Dis 1998, 27:S117-S124.
    • (1998) Clin Infect Dis , vol.27
    • Quinn, J.P.1
  • 2
    • 21244471489 scopus 로고    scopus 로고
    • Hospital outbreak caused by a carbapenem-resistant strain of Acinetobacter baumannii: patient prognosis and risk-factors for colonisation and infection
    • del Mar Tomas M., Cartelle M., Pertega S., Beceiro A., Llinares P., Canle D., et al. Hospital outbreak caused by a carbapenem-resistant strain of Acinetobacter baumannii: patient prognosis and risk-factors for colonisation and infection. Clin Microbiol Infect 2005, 11:540-546.
    • (2005) Clin Microbiol Infect , vol.11 , pp. 540-546
    • del Mar Tomas, M.1    Cartelle, M.2    Pertega, S.3    Beceiro, A.4    Llinares, P.5    Canle, D.6
  • 3
    • 0037043221 scopus 로고    scopus 로고
    • Citywide clonal outbreak of multiresistant Acinetobacter baumannii and Pseudomonas aeruginosa in Brooklyn, NY: the preantibiotic era has returned
    • Landman D., Quale J.M., Mayorga D., Adedeji A., Vangala K., Ravishankar J., et al. Citywide clonal outbreak of multiresistant Acinetobacter baumannii and Pseudomonas aeruginosa in Brooklyn, NY: the preantibiotic era has returned. Arch Intern Med 2002, 162:1515-1520.
    • (2002) Arch Intern Med , vol.162 , pp. 1515-1520
    • Landman, D.1    Quale, J.M.2    Mayorga, D.3    Adedeji, A.4    Vangala, K.5    Ravishankar, J.6
  • 4
    • 0037325502 scopus 로고    scopus 로고
    • Infections due to Acinetobacter baumannii in the ICU
    • Chastre J. Infections due to Acinetobacter baumannii in the ICU. Semin Respir Crit Care Med 2003, 24:69-78.
    • (2003) Semin Respir Crit Care Med , vol.24 , pp. 69-78
    • Chastre, J.1
  • 7
    • 0034460147 scopus 로고    scopus 로고
    • Emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multiresistant Acinetobacter baumannii
    • Corbella X., Montero A., Pujol M., Domínguez M.A., Ayats J., Argerich M.J., et al. Emergence and rapid spread of carbapenem resistance during a large and sustained hospital outbreak of multiresistant Acinetobacter baumannii. J Clin Microbiol 2000, 38:4086-4095.
    • (2000) J Clin Microbiol , vol.38 , pp. 4086-4095
    • Corbella, X.1    Montero, A.2    Pujol, M.3    Domínguez, M.A.4    Ayats, J.5    Argerich, M.J.6
  • 8
    • 17644389620 scopus 로고    scopus 로고
    • Colistin: the revival of polymyxins for the management of multidrug-resistant Gram-negative bacterial infections
    • Falagas M.E., Kasiakou S.K. Colistin: the revival of polymyxins for the management of multidrug-resistant Gram-negative bacterial infections. Clin Infect Dis 2005, 40:1333-1341.
    • (2005) Clin Infect Dis , vol.40 , pp. 1333-1341
    • Falagas, M.E.1    Kasiakou, S.K.2
  • 9
    • 33748743274 scopus 로고    scopus 로고
    • Colistin as a salvage therapy for nosocomial infections caused by multidrug-resistant bacteria in the ICU
    • Kallel H., Bahloul M., Hergafi L., Akrout M., Ketata W., Chelly H., et al. Colistin as a salvage therapy for nosocomial infections caused by multidrug-resistant bacteria in the ICU. Int J Antimicrob Agents 2006, 28:366-369.
    • (2006) Int J Antimicrob Agents , vol.28 , pp. 366-369
    • Kallel, H.1    Bahloul, M.2    Hergafi, L.3    Akrout, M.4    Ketata, W.5    Chelly, H.6
  • 11
    • 13844311296 scopus 로고    scopus 로고
    • Colistin treatment in patients with ICU-acquired infections caused by multiresistant Gram-negative bacteria: the renaissance of an old antibiotic
    • Michalopoulos A.S., Tsiodras S., Rellos K., Mentzelopoulos S., Falagas M.E. Colistin treatment in patients with ICU-acquired infections caused by multiresistant Gram-negative bacteria: the renaissance of an old antibiotic. Clin Microbiol Infect 2005, 11:115-121.
    • (2005) Clin Microbiol Infect , vol.11 , pp. 115-121
    • Michalopoulos, A.S.1    Tsiodras, S.2    Rellos, K.3    Mentzelopoulos, S.4    Falagas, M.E.5
  • 12
    • 34848875742 scopus 로고    scopus 로고
    • Outcomes of Acinetobacter baumannii infection in critically ill surgical patients
    • Trottier V., Namias N., Pust D.G., Nuwayhid Z., Manning R., Marttos A.C., et al. Outcomes of Acinetobacter baumannii infection in critically ill surgical patients. Surg Infect 2007, 8:437-443.
    • (2007) Surg Infect , vol.8 , pp. 437-443
    • Trottier, V.1    Namias, N.2    Pust, D.G.3    Nuwayhid, Z.4    Manning, R.5    Marttos, A.C.6
  • 13
    • 0032939527 scopus 로고    scopus 로고
    • Intravenous colistin as therapy for nosocomial infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii
    • Levin A.S., Barone A.A., Penço J., Santos M.V., Marinho I.S., Arruda E.A., et al. Intravenous colistin as therapy for nosocomial infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii. Clin Infect Dis 1999, 28:1008-1011.
    • (1999) Clin Infect Dis , vol.28 , pp. 1008-1011
    • Levin, A.S.1    Barone, A.A.2    Penço, J.3    Santos, M.V.4    Marinho, I.S.5    Arruda, E.A.6
  • 14
    • 0036093514 scopus 로고    scopus 로고
    • Efficacy of colistin versus beta-lactams, aminoglycosides, and rifampin as monotherapy in a mouse model of pneumonia caused by multiresistant Acinetobacter baumannii
    • Montero A., Ariza J., Corbella X., Doménech A., Cabellos C., Ayats J., et al. Efficacy of colistin versus beta-lactams, aminoglycosides, and rifampin as monotherapy in a mouse model of pneumonia caused by multiresistant Acinetobacter baumannii. Antimicrob Agents Chemother 2002, 46:1946-1952.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1946-1952
    • Montero, A.1    Ariza, J.2    Corbella, X.3    Doménech, A.4    Cabellos, C.5    Ayats, J.6
  • 15
    • 23844502584 scopus 로고    scopus 로고
    • Nebulized colistin in the treatment of pneumonia due to multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa
    • Kwa A.L., Loh C., Low J.G., Kurup A., Tam V.H. Nebulized colistin in the treatment of pneumonia due to multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa. Clin Infect Dis 2005, 41:754-757.
    • (2005) Clin Infect Dis , vol.41 , pp. 754-757
    • Kwa, A.L.1    Loh, C.2    Low, J.G.3    Kurup, A.4    Tam, V.H.5
  • 16
    • 34547735143 scopus 로고    scopus 로고
    • Efficacy and safety of colistin (colistimethate sodium) for therapy of infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii in Siriraj Hospital, Bangkok, Thailand
    • Koomanachai P., Tiengrim S., Kiratisin P., Thamlikitkul V. Efficacy and safety of colistin (colistimethate sodium) for therapy of infections caused by multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii in Siriraj Hospital, Bangkok, Thailand. Int J Infect Dis 2007, 11:402-406.
    • (2007) Int J Infect Dis , vol.11 , pp. 402-406
    • Koomanachai, P.1    Tiengrim, S.2    Kiratisin, P.3    Thamlikitkul, V.4
  • 18
    • 0028331552 scopus 로고
    • Prevention of Gram negative nosocomial bronchopneumonia by intratracheal colistin in critically ill patients. Histologic and bacteriologic study
    • Rouby J.J., Poète P., Martin de Lassale E., Nicolas M.H., Bodin L., Jarlier V., et al. Prevention of Gram negative nosocomial bronchopneumonia by intratracheal colistin in critically ill patients. Histologic and bacteriologic study. Intensive Care Med 1994, 20:187-192.
    • (1994) Intensive Care Med , vol.20 , pp. 187-192
    • Rouby, J.J.1    Poète, P.2    Martin de Lassale, E.3    Nicolas, M.H.4    Bodin, L.5    Jarlier, V.6
  • 19
    • 77955159963 scopus 로고    scopus 로고
    • Inhaled colistin as adjunctive therapy to intravenous colistin for the treatment of microbiologically documented ventilator-associated pneumonia: a comparative cohort study
    • Korbila I.P., Michalopoulos A., Rafailidis P.I., Nikita D., Samonis G., Falagas M.E. Inhaled colistin as adjunctive therapy to intravenous colistin for the treatment of microbiologically documented ventilator-associated pneumonia: a comparative cohort study. Clin Microbiol Infect 2010, 16:1230-1236.
    • (2010) Clin Microbiol Infect , vol.16 , pp. 1230-1236
    • Korbila, I.P.1    Michalopoulos, A.2    Rafailidis, P.I.3    Nikita, D.4    Samonis, G.5    Falagas, M.E.6
  • 20
    • 38749095520 scopus 로고    scopus 로고
    • Aerosolized colistin as adjunctive treatment of ventilator-associated pneumonia due to multidrug-resistant Gram-negative bacteria: a prospective study
    • Michalopoulos A., Fotakis D., Virtzili S., Vletsas C., Raftopoulou S., Mastora Z., Falagas M.E. Aerosolized colistin as adjunctive treatment of ventilator-associated pneumonia due to multidrug-resistant Gram-negative bacteria: a prospective study. Respir Med 2008, 102:407-412.
    • (2008) Respir Med , vol.102 , pp. 407-412
    • Michalopoulos, A.1    Fotakis, D.2    Virtzili, S.3    Vletsas, C.4    Raftopoulou, S.5    Mastora, Z.6    Falagas, M.E.7
  • 22
    • 36448980984 scopus 로고    scopus 로고
    • Administration of antimicrobials via the respiratory tract for the treatment of patients with nosocomial pneumonia: a meta-analysis
    • Ioannidou E., Siempos I.I., Falagas M.E. Administration of antimicrobials via the respiratory tract for the treatment of patients with nosocomial pneumonia: a meta-analysis. J Antimicrob Chemother 2007, 60:1216-1226.
    • (2007) J Antimicrob Chemother , vol.60 , pp. 1216-1226
    • Ioannidou, E.1    Siempos, I.I.2    Falagas, M.E.3
  • 23
    • 13644269309 scopus 로고    scopus 로고
    • Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia
    • American Thoracic Society/Infectious Diseases Society of America
    • Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005, 171:388-416. American Thoracic Society/Infectious Diseases Society of America.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 388-416
  • 25
    • 77954387227 scopus 로고    scopus 로고
    • Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa
    • Lu Q., Girardi C., Zhang M., Bouhemad B., Louchahi K., Lu Q.O., et al. Nebulized and intravenous colistin in experimental pneumonia caused by Pseudomonas aeruginosa. Intensive Care Med 2010, 36:1147-1155.
    • (2010) Intensive Care Med , vol.36 , pp. 1147-1155
    • Lu, Q.1    Girardi, C.2    Zhang, M.3    Bouhemad, B.4    Louchahi, K.5    Lu, Q.O.6
  • 26
    • 69349095937 scopus 로고    scopus 로고
    • Intratracheal colistin sulfate for BALB/c mice with early pneumonia caused by carbapenem-resistant Acinetobacter baumannii
    • Chiang S.R., Chuang Y.C., Tang H.J., Chen C.C., Chen C.H., Lee N.Y., et al. Intratracheal colistin sulfate for BALB/c mice with early pneumonia caused by carbapenem-resistant Acinetobacter baumannii. Crit Care Med 2009, 37:2590-2595.
    • (2009) Crit Care Med , vol.37 , pp. 2590-2595
    • Chiang, S.R.1    Chuang, Y.C.2    Tang, H.J.3    Chen, C.C.4    Chen, C.H.5    Lee, N.Y.6
  • 27
    • 18444401720 scopus 로고    scopus 로고
    • Influence of lung aeration on pulmonary concentrations of nebulized and intravenous amikacin in ventilated piglets with severe bronchopneumonia
    • Experimental ICU Study Group
    • Elman M., Goldstein I., Marquette C.H., Wallet F., Lenaour G., Rouby J.J. Influence of lung aeration on pulmonary concentrations of nebulized and intravenous amikacin in ventilated piglets with severe bronchopneumonia. Anesthesiology 2002, 97:199-206. Experimental ICU Study Group.
    • (2002) Anesthesiology , vol.97 , pp. 199-206
    • Elman, M.1    Goldstein, I.2    Marquette, C.H.3    Wallet, F.4    Lenaour, G.5    Rouby, J.J.6
  • 29
    • 4444256217 scopus 로고    scopus 로고
    • Disposition of instilled versus nebulized tobramycin and imipenem in ventilated intensive care unit (ICU) patients
    • Badia J.R., Soy D., Adrover M., Ferrer M., Sarasa M., Alarcón A., et al. Disposition of instilled versus nebulized tobramycin and imipenem in ventilated intensive care unit (ICU) patients. J Antimicrob Chemother 2004, 54:508-514.
    • (2004) J Antimicrob Chemother , vol.54 , pp. 508-514
    • Badia, J.R.1    Soy, D.2    Adrover, M.3    Ferrer, M.4    Sarasa, M.5    Alarcón, A.6
  • 30
    • 52649164215 scopus 로고    scopus 로고
    • Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing.
    • 17th Informational supplement. M100-S17. Wayne, PA: Clinical and Laboratory Standards Institute;
    • Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. 17th Informational supplement. M100-S17. Wayne, PA: Clinical and Laboratory Standards Institute; 2007.
    • (2007)
  • 31
    • 1242352596 scopus 로고    scopus 로고
    • In vitro and in vivo activity of meropenem and sulbactam against a multidrug-resistant Acinetobacter baumannii strain
    • Ko W.C., Lee H.C., Chiang S.R., Yan J.J., Wu J.J., Lu C.L., Chuang Y.C. In vitro and in vivo activity of meropenem and sulbactam against a multidrug-resistant Acinetobacter baumannii strain. J Antimicrob Chemother 2004, 53:393-395.
    • (2004) J Antimicrob Chemother , vol.53 , pp. 393-395
    • Ko, W.C.1    Lee, H.C.2    Chiang, S.R.3    Yan, J.J.4    Wu, J.J.5    Lu, C.L.6    Chuang, Y.C.7
  • 32
    • 0031759629 scopus 로고    scopus 로고
    • Efficacies of cefepime, ceftazidime, and imipenem alone or in combination with amikacin in rats with experimental pneumonia due to ceftazidime-susceptible or resistant Enterobacter cloacae strains
    • Mimoz O., Jacolot A., Leotard S., Hidri N., Samii K., Nordmann P., Petitjean O. Efficacies of cefepime, ceftazidime, and imipenem alone or in combination with amikacin in rats with experimental pneumonia due to ceftazidime-susceptible or resistant Enterobacter cloacae strains. Antimicrob Agents Chemother 1998, 42:3304-3308.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 3304-3308
    • Mimoz, O.1    Jacolot, A.2    Leotard, S.3    Hidri, N.4    Samii, K.5    Nordmann, P.6    Petitjean, O.7
  • 33
    • 0010102801 scopus 로고
    • Antimicrobial assays
    • Springer, New York, USA, J.A. Washington (Ed.)
    • Anhalt J.P. Antimicrobial assays. Laboratory procedures in clinical microbiology. 1985, 691-729. Springer, New York, USA. J.A. Washington (Ed.).
    • (1985) Laboratory procedures in clinical microbiology. , pp. 691-729
    • Anhalt, J.P.1
  • 34
    • 33744454666 scopus 로고    scopus 로고
    • Colistin methanesulfonate is an inactive prodrug of colistin against Pseudomonas aeruginosa
    • Bergen P.J., Li J., Rayner C.R., Nation R.L. Colistin methanesulfonate is an inactive prodrug of colistin against Pseudomonas aeruginosa. Antimicrob Agents Chemother 2006, 50:1953-1958.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1953-1958
    • Bergen, P.J.1    Li, J.2    Rayner, C.R.3    Nation, R.L.4
  • 35
    • 35348937025 scopus 로고    scopus 로고
    • Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model
    • Kroeger L.A., Hovde L.B., Mitropoulos I.F., Schafer J., Rotschafer J.C. Colistin methanesulfonate against multidrug-resistant Acinetobacter baumannii in an in vitro pharmacodynamic model. Antimicrob Agents Chemother 2007, 51:3431-3433.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3431-3433
    • Kroeger, L.A.1    Hovde, L.B.2    Mitropoulos, I.F.3    Schafer, J.4    Rotschafer, J.C.5
  • 36
    • 0345865147 scopus 로고    scopus 로고
    • Clinical features of pandrug-resistant Acinetobacter baumannii bacteremia at a university hospital in Taiwan
    • Kuo L.C., Yu C.J., Lee L.N., Wang J.L., Wang H.C., Hsueh P.R., Yang P.C. Clinical features of pandrug-resistant Acinetobacter baumannii bacteremia at a university hospital in Taiwan. J Formos Med Assoc 2003, 102:601-606.
    • (2003) J Formos Med Assoc , vol.102 , pp. 601-606
    • Kuo, L.C.1    Yu, C.J.2    Lee, L.N.3    Wang, J.L.4    Wang, H.C.5    Hsueh, P.R.6    Yang, P.C.7
  • 37
    • 0028927237 scopus 로고
    • The comparative inhibitory and bactericidal activities of meropenem and imipenem against Acinetobacter spp. and Enterobacteriaceae resistant to second generation cephalosporins
    • MacGowan A.P., Bowker K.E., Bedford K.A., Holt H.A., Reeves D.S., Hedges A. The comparative inhibitory and bactericidal activities of meropenem and imipenem against Acinetobacter spp. and Enterobacteriaceae resistant to second generation cephalosporins. J Antimicrob Chemother 1995, 35:333-337.
    • (1995) J Antimicrob Chemother , vol.35 , pp. 333-337
    • MacGowan, A.P.1    Bowker, K.E.2    Bedford, K.A.3    Holt, H.A.4    Reeves, D.S.5    Hedges, A.6
  • 38
    • 0034211207 scopus 로고    scopus 로고
    • Meropenem versus imipenem/cilastatin as empirical monotherapy for serious bacterial infections in the intensive care unit
    • Belgian Multicenter Study Group
    • Verwaest C. Meropenem versus imipenem/cilastatin as empirical monotherapy for serious bacterial infections in the intensive care unit. Clin Microbiol Infect 2002, 6:294-302. Belgian Multicenter Study Group.
    • (2002) Clin Microbiol Infect , vol.6 , pp. 294-302
    • Verwaest, C.1
  • 40
    • 0037378043 scopus 로고    scopus 로고
    • Stability of colistin and colistin methanesulfonate in aqueous media and plasma studied by high-performance liquid chromatography
    • Li J., Milne R.W., Nation R.L., Turnidge J.D., Coulthard K. Stability of colistin and colistin methanesulfonate in aqueous media and plasma studied by high-performance liquid chromatography. Antimicrob Agents Chemother 2003, 47:1364-1370.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 1364-1370
    • Li, J.1    Milne, R.W.2    Nation, R.L.3    Turnidge, J.D.4    Coulthard, K.5
  • 41
    • 2442644015 scopus 로고    scopus 로고
    • Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate
    • Li J., Milne R.W., Nation R.L., Turnidge J.D., Smeaton T.C., Coulthard K. Pharmacokinetics of colistin methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate. J Antimicrob Chemother 2004, 53:837-840.
    • (2004) J Antimicrob Chemother , vol.53 , pp. 837-840
    • Li, J.1    Milne, R.W.2    Nation, R.L.3    Turnidge, J.D.4    Smeaton, T.C.5    Coulthard, K.6
  • 42
    • 0026643687 scopus 로고
    • Endotracheal and aerosol administrations of ceftazidime in patients with nosocomial pneumonia: pharmacokinetics and absolute bioavailability
    • Bressolle F., de la Coussaye J.E., Ayoub R., Fabre D., Gomeni R., Saissi G., et al. Endotracheal and aerosol administrations of ceftazidime in patients with nosocomial pneumonia: pharmacokinetics and absolute bioavailability. Antimicrob Agents Chemother 1992, 36:1404-1411.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 1404-1411
    • Bressolle, F.1    de la Coussaye, J.E.2    Ayoub, R.3    Fabre, D.4    Gomeni, R.5    Saissi, G.6
  • 43
    • 0031975321 scopus 로고    scopus 로고
    • Aerosolized antibiotics in mechanically ventilated patients: delivery and response
    • Palmer L.B., Smaldone G.C., Simon S.R., O'Riordan T.G., Cuccia A. Aerosolized antibiotics in mechanically ventilated patients: delivery and response. Crit Care Med 1998, 26:31-39.
    • (1998) Crit Care Med , vol.26 , pp. 31-39
    • Palmer, L.B.1    Smaldone, G.C.2    Simon, S.R.3    O'Riordan, T.G.4    Cuccia, A.5
  • 45
    • 0027935736 scopus 로고
    • Penetration of meropenem into the cerebrospinal fluid of patients with inflamed meninges
    • Dagan R., Velghe L., Rodda J.L., Klugman K.P. Penetration of meropenem into the cerebrospinal fluid of patients with inflamed meninges. J Antimicrob Chemother 1994, 34:175-179.
    • (1994) J Antimicrob Chemother , vol.34 , pp. 175-179
    • Dagan, R.1    Velghe, L.2    Rodda, J.L.3    Klugman, K.P.4
  • 46
    • 0031952586 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men
    • Craig W.A. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis 1998, 26:1-12.
    • (1998) Clin Infect Dis , vol.26 , pp. 1-12
    • Craig, W.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.