Process optimization studies of 10-Hydroxycamptothecin (HCPT)-loaded folate-conjugated chitosan nanoparticles by SAS-ionic crosslink combination using response surface methodology (RSM)

Applied Surface Science

Volumn 258, Issue 6, 2012, Pages 2000-2005

  Zhao, Xiuhua ^a   Jiang, Ru ^a   Zu, Yuangang ^a   Wang, Ying ^a   Zhao, Qi ^a   Zu, Baishi ^a   Zhao, Dongmei ^a   Wang, Meixiang ^a   Sun, Zhiqiang ^a  

^a NORTHEAST FORESTRY UNIVERSITY   (China)

Author keywords

10 Hydroxycamptothecin (HCPT); Chitosan; Ionic crosslink; Response surface method (RSM); SAS; Target

Indexed keywords

CHITOSAN; EFFICIENCY; NANOPARTICLES; OPTIMIZATION; PARTICLE SIZE; SUPERCRITICAL FLUID EXTRACTION; SURFACE PROPERTIES; TARGETS;

10 HYDROXYCAMPTOTHECIN (HCPT); CENTRAL COMPOSITE DESIGNS; CHITOSAN CONCENTRATION; IONIC CROSSLINK; NANOPARTICLE CONCENTRATIONS; RESPONSE SURFACE METHOD; RESPONSE SURFACE METHODOLOGY; SUPERCRITICAL ANTISOLVENTS;

TARGETED DRUG DELIVERY;

EID: 84855294024     PISSN: 01694332     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apsusc.2011.05.066     Document Type: Article

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