A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators

Arthritis and Rheumatism

Volumn 64, Issue 1, 2012, Pages 264-271

  Broen, J C A ^a   Bossini Castillo, L ^b   Van Bon, L ^a   Vonk, M C ^a   Knaapen, H ^a   Beretta, L ^c   Rueda, B ^b   Hesselstrand, R ^d   Herrick, A ^e,n   Worthington, J ^e,n   Hunzelman, N ^f   Denton, C P ^g   Fonseca, C ^g   Riemekasten, G ^h   Kiener, H P ⁱ   Scorza, R ^c   Simeon C P ^j   Ortego Centeno, N ^k   Gonzalez Gay, M A ^l   Airo P ^m   Coenen, M J H ^a   Martin J ^b   Radstake, T R D J ^a   more..

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^c UNIVERSITY OF MILAN   (Italy)

^d LUND UNIVERSITY   (Sweden)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f UNIVERSITY OF COLOGNE   (Germany)

^g ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^h CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

ⁱ MEDICAL UNIVERSITY OF VIENNA   (Austria)

^j HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^k HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^l HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^m SPEDALI CIVILI   (Italy)

ⁿ SALFORD ROYAL NHS FOUNDATION TRUST   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; INTERLEUKIN 6; PROLINE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL FUNCTION; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; FOLLOW UP; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE; HUMAN; LUNG FIBROSIS; MAJOR CLINICAL STUDY; MALE; MONOCYTE; PHENOTYPE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; REPLICATION STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC SCLEROSIS;

COHORT STUDIES; COMORBIDITY; DENDRITIC CELLS; EUROPE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION, PULMONARY; INTERLEUKIN-6; MALE; MONOCYTES; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PULMONARY ARTERY; SCLERODERMA, SYSTEMIC; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84855281875     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.33325     Document Type: Article

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