Peripheral blood CD64 levels decrease in Crohn's disease following granulocyte and monocyte adsorptive apheresis

Case Reports in Gastroenterology

Volumn 5, Issue 3, 2011, Pages 667-671

  Chiba, Toshimi ^a   Endo, Mikiya ^a   Matsushita, Shoko ^a   Sasaki, Mika ^a   Chida, Shoichi ^a   Toya, Yosuke ^a   Kasugai, Satoshi ^a   Matsuda, Nozomi ^a   Orikasa, Shunsuke ^a   Abiko, Yukito ^a   Kudara, Norihiko ^a   Oana, Shuhei ^a   Endo, Masaki ^a   Suzuki, Kazuyuki ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

CD64; Crohn's disease; Granulocyte and monocyte adsorptive apheresis

Indexed keywords

ADALIMUMAB; CD64 ANTIGEN; INFLIXIMAB;

ADULT; APHERESIS; ARTICLE; CASE REPORT; CROHN DISEASE; DISEASE SEVERITY; FEMALE; FLOW CYTOMETRY; GRANULOCYTE; GRANULOCYTE AND MONOCYTE ADSORPTIVE APHERESIS; HUMAN; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT DURATION;

EID: 84855276870     PISSN: None     EISSN: 16620631     Source Type: Journal    
DOI: 10.1159/000335316     Document Type: Article

References (15)

1. Hanauer SB, Feagan BG, Lichtenstein GR, et al.: Maintenance infliximab for Crohn's disease: the ACCENT 1 randomised trial. Lancet 2002;359:1541-1549. (Pubitemid 34621118)
2. Regueiro M, Schraut W, Baidoo L, et al.: Infliximab prevents Crohn's disease recurrence after ileal resection. Gastroenterology 2009;136:441-450.
3. Peluso I, Pallone F, Monteleone G: Interleukin-12 and Th1 immune response in Crohn's disease: pathogenetic relevance and therapeutic implication. World J Gastroenterol 2006;12:5606-5610. (Pubitemid 44594033)
4. Feldmann M, Fionula M: Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 1996;14:397-440. (Pubitemid 26130190)
5. Danese S, Sans M, Scaldaferri F, et al.: TNF-á blockade down-regulates the CD40/CD40L pathway in the mucosal microcirculation: a novel anti-inflammatory mechanism of infliximab in Crohn's disease. J Immunol 2006;176:2617-2624. (Pubitemid 43201714)
6. Kono T, Kamikozuru K, Yokoyama Y, et al.: Immunoregulatory effects of adsorptive granulocyte and monocyte apheresis in patients with drug refractory Crohn's disease. Ther Apher Dial 2011;15:367-373.
7. Buckle AM, Hogg N: The effect of IFN-ã and colony-stimulating factors on the expression of neutrophil cell membrane receptors. J Immunol 1989;143:2295-2301.
8. Cuadrado E, Alonso M, de Juan MD, Echaniz P, Arenas JI: Regulatory T cells in patients with inflammatory bowel diseases treated with adacolumn granulocytapheresis. World J Gastroenterol 2008;14:1521-1527. (Pubitemid 351460165)
9. Sakuraba A, Motoya S, Watanabe K, et al.: An open-label prospective randomized multicenter study shows very rapid remission of ulcerative colitis by intensive granulocyte and monocyte adsorptive apheresis as compared with routine weekly treatment. Am J Gastroenterol 2009;104:2990-2995.
10. Best WR, Becktel JM, Singleton JW, Kern F Jr: Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology 1976;70:439-444.
11. Shimoyama T, Sawada K, Hiwatashi N, et al.: Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: a multicenter study. J Clin Apher 2001;16:1-9.
12. Ng PC, Li K, Wong RP, et al.: Neutrophil CD64 expression: a sensitive diagnostic marker for late-onset nosocomial infection in very low birth weight infants. Pediatr Res 2002;51:296-303. (Pubitemid 34174964)
13. Matsui T, Ohsumi K, Ozawa N, et al.: CD64 on neutrophils is a sensitive and specific marker for detection of infection in patients with rheumatoid arthritis. J Rheumatol 2006;33:2416-2424. (Pubitemid 46067820)
14. Tillinger W, Gasche C, Reinisch W, et al.: Influence of topically and systemically active steroids on circulating leukocytes in Crohn's disease. Am J Gastroenterol 1998;93:1848-1853. (Pubitemid 29071693)
15. Tillinger W, Jilch R, Jilma B, et al.: Expression of the high-affinity IgG receptor FcRI (CD64) in patients with inflammatory bowel disease: a new biomarker for gastroenterologic diagnostics. Am J Gastroenterol 2009;104:102-109.