An improved synthesis of N-(3-phenylbicyclo[2.2.1]-yl)-N-ethylamine hydrochloride (Fencamfamine)

Pharmaceutical Chemistry Journal

Volumn 45, Issue 7, 2011, Pages 419-422

  Novakov, I A ^a   Orlinson, B S ^a   Brunilin, R V ^a   Navrotskii, M B ^a   Eremiichuk, A S ^a   Dumler, S A ^a   Gordeeva, E A ^a  

^a VOLGOGRAD STATE TECHNICAL UNIVERSITY   (Russian Federation)

Author keywords

Fencamfamine; N (3 phenyl 2.2.1 bicyclohept 2 yl) N ethylamine hydrochloride

Indexed keywords

ALCOHOL; ALLOY; FENCAMFAMIN; NICKEL; SODIUM HYDROXIDE; TETRAHYDROFURAN;

ALKYLATION; AQUEOUS SOLUTION; NOTE; REDUCTION; SYNTHESIS;

EID: 84855264642     PISSN: 0091150X     EISSN: 15739031     Source Type: Journal    
DOI: 10.1007/s11094-011-0646-3     Document Type: Note

References (14)

1. GB Patent 913866 (1992).
2. G. Vollberg, Dissertation, Universität Bonn (1992).
3. The Merck Index, Merck & Co Inc., New York (2001).
4. M. L. Aizenstein, C. Scavone, M. M. Bernardi, and R. DeLucia, Prog. Neuropsychopharmacol. Biol. Psychiatry, 7(2-3), 187-194 (1983).
5. C. Gorenstein, R. DeLucia, and V. Gentil, Braz. J. Ed. Biol. Res., 21(3), 475-477 (1988).
6. R. DeLucia, and C. S. Planeta, Gen. Pharmacol., 21(2), 161-163 (1990).
7. D. R. Laurence and P. N. Benett, Clinical Pharmacology [Russian translation], Meditsina, Moscow (1991), Vol. 2.
8. P. J. van der Merwe and H. S. Kruger, S. Afr. Med. J., 82(3), 151-153 (1992).
9. C. S. Planeta, M. L. Aizenstein, and R. DeLucia, Pharmacol. Biochem. Behav., 50(1), 35-40 (1995).
10. C. F. H. Allen and A. Bell, J. Amer. Chem. Soc., 61, 521-522 (1939).
11. C. F. H. Allen, A. Bell, and J. W. Gates, Jr., J. Org. Chem., 8, 373-379 (1943).
12. W. E. Parham, W. T. Hunter, and R. Hanson, J. Amer. Chem. Soc., 73, 5068-5070 (1951).
13. G. Rucker, M. Neugebauer, and G. Vollberg, Arch. Pharm. (Weinheim), 327, 295-298 (1994).
14. K. Johnson and E. D. Degering, J. Amer. Chem. Soc., 61, 319 (1939).