Positive ion MALDI-TOF mass spectra are more suitable than negative ion spectra to characterize sulphated glycosaminoglycan oligosaccharides

International Journal of Mass Spectrometry

Volumn 310, Issue , 2012, Pages 72-76

  Nimptsch, Kathrin ^a   Süß, Rosmarie ^a   Schnabelrauch, Matthias ^b   Nimptsch, Ariane ^a   Schiller, Jürgen ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b BIOMATERIALS DEPARTMENT   (Germany)

Author keywords

9 AA (9 aminoacridine); Chondroitin sulphate oversulphated chondroitin; DHB (2,5 dihydroxybenzoic acid); Hyaluronan; MALDI; Sulphate loss

Indexed keywords

EID: 84855247461     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2011.11.003     Document Type: Article

References (22)

1. J. Schiller, J. Becher, S. Möller, K. Nimptsch, T. Riemer, and M. Schnabelrauch Synthesis and characterization of chemically modified glycosaminoglycans of the extracellular matrix Mini-Rev. Org. Chem. 7 2010 290 299
2. N. Volpi Therapeutic applications of glycosaminoglycans Curr. Med. Chem. 13 2006 1799 1810 (Pubitemid 43871757)
3. J. Schiller, N. Volpi, E. Hrabárová, and L. Soltés Hyaluronic acid: a natural biopolymer S. Kalia, Handbook of Biopolymers and their Applications 2011 Scrivener Publishing LLC Salem 3 34
4. C.I. Gama, and L.C. Hsieh-Wilson Chemical approaches to deciphering the glycosaminoglycan code Curr. Opin. Chem. Biol. 9 2005 609 619 (Pubitemid 41612188)
5. J. Kovensky Sulfated oligosaccharides: new targets for drug development? Curr. Med. Chem. 16 2009 2338 2344
6. A. Nimptsch, S. Schibur, M. Schnabelrauch, B. Fuchs, D. Huster, and J. Schiller Characterization of the quantitative relationship between signal-to-noise (S/N) ratio and sample amount on-target by MALDI-TOF MS: determination of chondroitin sulfate subsequent to enzymatic digestion Anal. Chim. Acta 635 2009 175 182
7. E. Sisu, C. Flangea, A. Serb, and A.D. Zamfir Modern developments in mass spectrometry of chondroitin and dermatan sulfate glycosaminoglycans Amino Acids 41 2011 235 256
8. J. Zaia Principles of mass spectrometry of glycosaminoglycans J. Biomacromol. Mass Spectrom. 1 2005 3 36
9. T.N. Laremore, S. Murugesan, T.J. Park, F.Y. Avci, D.V. Zagorevski, and R.J. Linhardt Matrix-assisted laser desorption/ionization mass spectrometric analysis of uncomplexed highly sulfated oligosaccharides using ionic liquid matrices Anal. Chem. 78 2006 1749 1774
10. J. Becher, A. Muck, A. Mithöfer, A. Svatos, and W. Boland Negative ion mode matrix-assisted laser desorption/ionisation time-of-flight mass spectrometric analysis of oligosaccharides using halide adducts and 9-aminoacridine matrix Rapid Commun. Mass Spectrom. 22 2008 1153 1158 (Pubitemid 351600763)
11. L. Bultel, M. Landoni, E. Grand, A.S. Couto, and J. Kovensky UV-MALDI-TOF mass spectrometry analysis of heparin oligosaccharides obtained by nitrous acid controlled degradation and high performance anion exchange chromatography J. Am. Soc. Mass Spectrom. 21 2010 178 190
12. H. Cheng, G. Sun, K. Yang, R.W. Gross, and X. Han Selective desorption/ionization of sulfatides by MALDI-MS facilitated using 9-aminoacridine as matrix J. Lipid Res. 51 2010 1599 1609
13. R.L. Vermillion-Salsbury, and D.M. Hercules 9-Aminoacridine as a matrix for negative mode matrix-assisted laser desorption/ionization Rapid Commun. Mass Spectrom. 16 2002 1575 1581
14. K. Nimptsch, R. Süß, T. Riemer, A. Nimptsch, M. Schnabelrauch, and J. Schiller Differently complex oligosaccharides can be easily identified by matrix-assisted laser desorption and ionization time-of-flight mass spectrometry directly from a standard thin-layer chromatography plate J. Chromatogr. A 1217 2010 3711 3715
15. T. Bitter, and H.M. Muir A modified uronic acid carbazole reaction Anal. Biochem. 4 1962 330 334
16. J. Schiller, J. Arnhold, S. Benard, S. Reichl, and K. Arnold Cartilage degradation by hyaluronate lyase and chondroitin ABC lyase: a MALDI-TOF mass spectrometric study Carbohydr. Res. 318 1999 116 122 (Pubitemid 29421790)
17. K. Busse, M. Averbeck, U. Anderegg, K. Arnold, J.C. Simon, and J. Schiller The signal-to-noise ratio as a measure of HA oligomer concentration: a MALDI-TOF MS study Carbohydr. Res. 341 2006 1065 1070
18. J. Schiller, R. Süß, B. Fuchs, M. Müller, M. Petković, O. Zschörnig, and H. Waschipky The suitability of different DHB isomers as matrices for the MALDI-TOF MS analysis of phospholipids: which isomer for what purpose? Eur. Biophys. J. 36 2007 517 527 (Pubitemid 46626207)
19. B. Fuchs, A. Bischoff, R. Süß, K. Teuber, M. Schürenberg, D. Suckau, and J. Schiller Phosphatidylcholines and -ethanolamines can be easily mistaken in phospholipid mixtures: a negative ion MALDI-TOF MS study with 9-aminoacridine as matrix and egg yolk as selected example Anal. Bioanal. Chem. 395 2009 2479 2487
20. G. Sun, K. Yang, Z. Zhao, S. Guan, X. Han, and R.W. Gross Matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of cellular glycerophospholipids enabled by multiplexed solvent dependent analyte-matrix interactions Anal. Chem. 80 2008 7576 7585
21. R. Shroff, A. Muck, and A. Svatos Analysis of low molecular weight acids by negative mode matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Rapid Commun. Mass Spectrom. 21 2007 3295 3300 (Pubitemid 47598780)
22. T.N. Laremore, and R.J. Linhardt Improved matrix-assisted laser desorption/ionization mass spectrometric detection of glycosaminoglycan disaccharides as cesium salts Rapid Commun. Mass Spectrom. 21 2007 1315 1320 (Pubitemid 46506587)