Fine structural characterization of chondroitin sulfate in urine of bladder pain syndrome subjects

International Urogynecology Journal

Volumn 22, Issue 12, 2011, Pages 1581-1586

  MacCari, Francesca ^a   Buzzega, Dania ^a   Galeotti, Fabio ^a   Volpi, Nicola ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Bladder pain syndrome; Chondroitin sulfate; Glycosaminoglycans; Heparan sulfate; Urine analysis

Indexed keywords

CHONDROITIN SULFATE; HEPARAN SULFATE;

ADULT; AGAR GEL ELECTROPHORESIS; AGED; ARTICLE; CARBOHYDRATE ANALYSIS; CLINICAL ASSESSMENT; CONTROLLED STUDY; CYSTALGIA; DENSITOMETRY; DISEASE MARKER; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRIORITY JOURNAL; PURIFICATION; SENSITIVITY ANALYSIS; STRUCTURE ANALYSIS; URINALYSIS; VALIDATION PROCESS;

EID: 84855238539     PISSN: 09373462     EISSN: 14333023     Source Type: Journal    
DOI: 10.1007/s00192-011-1534-9     Document Type: Article

References (23)

1. Hurst RE, Roy JB, Min KW, Veltri RW, Marley G, Patton K, Shackelford DL, Stein P, Parsons CL (1996) A deficit of chondroitin sulfate proteoglycans on the bladder uroepithelium in interstitial cystitis. Urology 48:817-821 (Pubitemid 26398711)
2. Dietrich CP, Martins JR, Sampaio LO, Nader HB (1993) Anomalous structure of urinary chondroitin sulfate from cancer patients. A potential new marker for diagnosis of neoplasias. Lab Invest 68:439-45 (Pubitemid 23136164)
3. Whitley CB, Ridnour MD, Draper KA, Dutton CM, Neglia JP (1989) Diagnostic test for mucopolysaccharidosis. I. Direct method for quantifying excessive urinary glycosaminoglycan excretion. Clin Chem 35:374-9 (Pubitemid 19086682)
4. Maccari F, Gheduzzi D, Volpi N (2003) Anomalous structure of urinary glycosaminoglycans in patients with pseudoxanthoma elasticum. Clin Chem 49:380-8 (Pubitemid 36250198)
5. Parsons CL, Lilly JD, Stein P (1991) Epithelial dysfunction in nonbacterial cystitis (interstitial cystitis). J Urol 145:732-735
6. Slobodov G, Feloney M, Gran C, Kyker KD, Hurst RE, Culkin DJ (2004) Abnormal expression of molecular markers for bladder impermeability and differentiation in the urothelium of patients with interstrtial cystitis. J Urol 171:1554-1558 (Pubitemid 38365417)
7. Erickson DR, Xie SX, Bhavanandan VP, Wheeler MA, Hurst RE, Demers LM, Kushner L, Keay SK (2002) A comparison of multiple urine markers for interstitial cystitis. J Urol 167:2461-9 (Pubitemid 34533146)
8. Volpi N (2007) Analytical aspects of pharmaceutical grade chondroitin sulfates. J Pharm Sci 96:3168-80
9. Volpi N (2006) Advances in chondroitin sulfate analysis: application in physiological and pathological states of connective tissue and during pharmacological treatment of osteoarthritis. Curr Pharm Des 12:639-58
10. Volpi N (1993) "Fast moving" and "slow moving" heparins, dermatan sulfate, and chondroitin sulfate: qualitative and quantitative analysis by agarose-gel electrophoresis. Carbohydr Res 247:263-78 (Pubitemid 23271883)
11. Volpi N (1999) Disaccharide analysis and molecular mass determination to microgram level of single sulfated glycosaminoglycan species in mixtures following agarose-gel electrophoresis. Analyt Biochem 273:229-39 (Pubitemid 29430667)
12. Wilkinson DR, Erickson AD (2006) Urinary and serologic markers for interstitial cystitis: an update. Curr Urol Rep 7:414-422 (Pubitemid 44884763)
13. Buzzega D, Pederzoli F, Maccari F, Aslan D, Türk M, Volpi N (2010) Comparison of CPC and CETAB extractive procedures for quantification and characterization of human urinary glycosami-noglycans. Clin Chem Lab Med 48:1133-1139
14. Cornish J, Nickel JC, Vanderwee M, Costerton JW (1990) Ultrastructural visualization of human bladder mucus. Urol Res 18:263-266 (Pubitemid 20294490)
15. Lilly JD, Parsons CL (1990) Bladder surface glycosaminoglycans is a human epithelial permeability barrier. Surg Gynecol Obstet 171:493-496
16. Hauser PJ, Dozmorov MG, Bane BL, Slobodov G, Culkin DJ, Hurst RE (2008) Abnormal expression of differentiation related proteins and proteoglycan core proteins in the urothelium of patients with interstitial cystitis. J Urol 179:764-769
17. Russell AL (1999) Glycoaminoglycan (GAG) deficiency in protective barrier as an underlying, primary cause of ulcerative colitis, Crohn's disease interstitial cystitis and possibly Reiter's syndrome. Med Hypotheses 52:297-301 (Pubitemid 29243568)
18. Lazzeri M, Montorsi F (2011) The therapeutic challenge of "chronic cystitis": search well, work together, and gain results. Eur Urol 60:78-80
19. Wei DC, Politano VA, Selzer MG, Lokeshwar VB (2000) The association of elevated urinary total to sulfated glycosaminogly-can ratio and high molecular mass hyaluronic acid with interstitial cystitis. J Urol 163:1577-1583 (Pubitemid 30226330)
20. Lokeshwar VB, Selzer MG, Unwala DJ, Estrella V, Gomez MF, Golshani R, Kester RR, Klumpp DJ, Gousse AE (2006) Uronate peaks and urinary hyaluronic acid levels correlate with interstitial cystitis severity. J Urol 176:1001-1007 (Pubitemid 44142561)
21. Lokeshwar VB, Selzer MG, Cerwinka WH, Gomez MF, Kester RR, Bejany DE, Gousse AE (2005) Urinary uronate and sulfated glycosaminoglycan levels: markers for interstitial cystitis severity. J Urol 174:344-349 (Pubitemid 40825755)
22. Hurst RE, Parsons CL, Roy JB, Young JL (1993) Urinary glycosaminoglycan excretion as a laboratory marker in the diagnosis of interstitial cystitis. J Urol 149:31-35 (Pubitemid 23095467)
23. Coppa GV, Galeotti F, Zampini L, Maccari F, Galeazzi T, Padelia L, Santoro L, Gabrielli O, Volpi N (2011) High-throughput determination of urinary hexosamines for diagnosis of mucopo-lysaccharidoses by capillary electrophoresis and HPLC. Analyt Biochem 411:32-42