Pleiotrophin triggers inflammation and increased peritoneal permeability leading to peritoneal fibrosis

Kidney International

Volumn 81, Issue 2, 2012, Pages 160-169

  Yokoi, Hideki ^a,b   Kasahara, Masato ^a,b   Mori, Kiyoshi ^a   Ogawa, Yoshihisa ^a   Kuwabara, Takashige ^a   Imamaki, Hirotaka ^a   Kawanishi, Tomoko ^a   Koga, Kenichi ^a   Ishii, Akira ^a   Kato, Yukiko ^a   Mori, Keita P ^a   Toda, Naohiro ^a   Ohno, Shoko ^a   Muramatsu, Hisako ^c   Muramatsu, Takashi ^c   Sugawara, Akira ^a   Mukoyama, Masashi ^a   Nakao, Kazuwa ^a  

^a KYOTO UNIVERSITY   (Japan)

^b INSTITUTE OF BIOMEDICAL RESEARCH AND INNOVATION   (Japan)

^c AICHI GAKUIN UNIVERSITY   (Japan)

Author keywords

continuous ambulatory peritoneal dialysis; microarray analysis; peritoneal dialysis; peritoneal membrane

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; INTERLEUKIN 1BETA; MESSENGER RNA; PLEIOTROPHIN; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; FIBROBLAST; GENE EXPRESSION PROFILING; GENE FUNCTION; HUMAN; LYMPHOCYTIC INFILTRATION; MESOTHELIUM CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERITONEAL DIALYSIS; PERITONEAL FIBROSIS; PERITONEUM; PRIORITY JOURNAL; PROTEIN FUNCTION; T LYMPHOCYTE; UPREGULATION;

EID: 84855206871     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.305     Document Type: Article

References (45)

1. Ledebo I, Ronco C. The best dialysis therapy? Results from an international survey among nephrology professionals. NDT Plus 2008; 1: 403-408.
2. Saxena R. Pathogenesis and treatment of peritoneal membrane failure. Pediatr Nephrol 2008; 23: 695-703. (Pubitemid 351486181)
3. Yung S, Chan TM. Preventing peritoneal fibrosis-insights from the laboratory. Perit Dial Int 2003; 23(S2): S37-S41.
4. Pecoits-Filho R, Araujo MR, Lindholm B, et al. Plasma and dialysate IL-6 and VEGF concentrations are associated with high peritoneal solute transport rate. Nephrol Dial Transplant 2002; 17: 1480-1486.
5. Lai KN, Lai KB, Szeto CC, et al. Growth factors in continuous ambulatory peritoneal dialysis effluent. Their relation with peritoneal transport of small solutes. Am J Nephrol 1999; 19: 416-422. (Pubitemid 29301227)
6. Oh KH, Jung JY, Yoon MO, et al. Intra-peritoneal interleukin-6 system is a potent determinant of the baseline peritoneal solute transport in incident peritoneal dialysis patients. Nephrol Dial Transplant 2010; 25: 1639-1646.
7. Margetts PJ, Kolb M, Galt T, et al. Gene transfer of transforming growth factor-b1 to the rat peritoneum: effects on membrane function. J Am Soc Nephrol 2001; 12: 2029-2039. (Pubitemid 32880339)
8. Margetts PJ, Kolb M, Yu L, et al. Inflammatory cytokines, angiogenesis, and fibrosis in the rat peritoneum. Am J Pathol 2002; 160: 2285-2294. (Pubitemid 34663419)
9. Aroeira LS, Aguilera A, Selgas R, et al. Mesenchymal conversion of mesothelial cells as a mechanism responsible for high solute transport rate in peritoneal dialysis: role of vascular endothelial growth factor. Am J Kidney Dis 2005; 46: 938-948. (Pubitemid 41505470)
10. Zakariael R, Matheson PJ, Hurt RT, et al. Chronic infusion of sterile peritoneal dialysis solution abrogates enhanced peritoneal gene expression responses to chronic peritoneal catheter presence. Adv Perit Dial 2008; 24: 7-15.
11. Deuel TF, Zhang N, Yeh HJ, et al. Pleiotrophin: a cytokine with diverse functions and a novel signaling pathway. Arch Biochem Biophys 2002; 397: 162-171. (Pubitemid 34852276)
12. Jin L, Jianghai C, Juan L, et al. Pleiotrophin and peripheral nerve injury. Neurosurg Rev 2009; 32: 387-393.
13. Muramatsu H, Zou P, Kurosawa N, et al. Female infertility in mice deficient in midkine and pleiotrophin, which form a distinct family of growth factors. Genes Cells 2006; 11: 1405-1417. (Pubitemid 44774203)
14. Lu KV, Jong KA, Kim GY, et al. Differential induction of glioblastoma migration and growth by two forms of pleiotrophin. J Biol Chem 2005; 280: 26953-26964. (Pubitemid 41040731)
15. Milner PG, Li YS, Hoffman RM, et al. A novel 17 kD heparin-binding growth factor (HBGF-8) in bovine uterus: purification and N-terminal amino acid sequence. Biochem Biophys Res Commun 1989; 165: 1096-1103. (Pubitemid 20029821)
16. Rauvala H. An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors. EMBO J 1989; 8: 2933-2941. (Pubitemid 19274995)
17. Sakurai H, Bush KT, Nigam SK. Identification of pleiotrophin as a mesenchymal factor involved in ureteric bud branching morphogenesis. Development 2001; 128: 3283-3293. (Pubitemid 32910381)
18. Amet LE, Lauri SE, Hienola A, et al. Enhanced hippocampal long-term potentiation in mice lacking heparin-binding growth-associated molecule. Mol Cell Neurosci 2001; 17: 1014-1024. (Pubitemid 32641870)
19. Ochiai K, Muramatsu H, Yamamoto S, et al. The role of midkine and pleiotrophin in liver regeneration. Liver Int 2004; 24: 484-491. (Pubitemid 40484563)
20. Yamamoto R, Nakayama M, Hasegawa T, et al. High-transport membrane is a risk factor for encapsulating peritoneal sclerosis developing after long-term continuous ambulatory peritoneal dialysis treatment. Adv Perit Dial 2002; 18: 131-134.
21. Kawanishi H, Moriishi M. Encapsulating peritoneal sclerosis: prevention and treatment. Perit Dial Int 2007; 27(S2): S289-S292. (Pubitemid 350047716)
22. Kawanishi H, Fujimori A, Tsuchida K, et al. Markers in peritoneal effluent for withdrawal from peritoneal dialysis: multicenter prospective study in Japan. Adv Perit Dial 2005; 21: 134-138.
23. Kawanishi H, Harada Y, Noriyuki T, et al. Treatment options for encapsulating peritoneal sclerosis based on progressive stage. Adv Perit Dial 2001; 17: 200-204.
24. Xu X, Rivkind A, Pappo O, et al. Role of mast cells and myofibroblasts in human peritoneal adhesion formation. Ann Surg 2002; 236: 593-601. (Pubitemid 35246891)
25. Dreyfus J, Brunet-de Carvalho N, Duprez D, et al. HB-GAM/pleiotrophin: localization of mRNA and protein in the chicken developing leg. Int J Dev Biol 1998; 42: 189-198. (Pubitemid 28109380)
26. Li YS, Gurrieri M, Deuel TF. Pleiotrophin gene expression is highly restricted and is regulated by platelet-derived growth factor. Biochem Biophys Res Commun 1992; 184: 427-432.
27. Li F, Tian F, Wang L, et al. Pleiotrophin (PTN) is expressed in vascularized human atherosclerotic plaques: IFN-g/JAK/STAT1 signaling is critical for the expression of PTN in macrophages. FASEB J 2010; 24: 810-822.
28. Meng K, Rodriguez-Pena A, Dimitrov T, et al. Pleiotrophin signals increased tyrosine phosphorylation of b-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase b/z. Proc Natl Acad Sci U S A 2000; 97: 2603-2608. (Pubitemid 30159217)
29. Stoica GE, Kuo A, Aigner A, et al. Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin. J Biol Chem 2001; 276: 16772-16779.
30. Raulo E, Chernousov MA, Carey DJ, et al. Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HBGAM). Identification as N-syndecan (syndecan-3). J Biol Chem 1994; 269: 12999-13004.
31. Mateijsen MA, van der Wal AC, Hendriks PM, et al. Vascular and interstitial changes in the peritoneum of CAPD patients with peritoneal sclerosis. Perit Dial Int 1999; 19: 517-525. (Pubitemid 30015564)
32. Saito H, Kitamoto M, Kato K, et al. Tissue factor and factor V involvement in rat peritoneal fibrosis. Perit Dial Int 2009; 29: 340-351.
33. Schilte MN, Celie JW, Wee PM, et al. Factors contributing to peritoneal tissue remodeling in peritoneal dialysis. Perit Dial Int 2009; 29: 605-617.
34. Glik A, Douvdevani A. T lymphocytes: the ?cellular? arm of acquired immunity in the peritoneum. Perit Dial Int 2006; 26: 438-448. (Pubitemid 44339976)
35. Devuyst O, Margetts PJ, Topley N. The pathophysiology of the peritoneal membrane. J Am Soc Nephrol 2010; 21: 1077-1085.
36. Achour A, M?Bika JB, Baudouin F, et al. Pleiotrophin induces expression of inflammatory cytokines in peripheral blood mononuclear cells. Biochimie 2008; 90: 1791-1795.
37. Endl E, Gerdes J. The Ki-67 Protein: Fascinating forms and an unknown function. Exp Cell Res 2000; 257: 231-237. (Pubitemid 30390473)
38. Ishii Y, Sawada T, Shimizu A, et al. An experimental sclerosing encapsulating peritonitis model in mice. Nephrol Dial Transplant 2001; 16: 1262-1266. (Pubitemid 32547385)
39. Yokoi H, Mukoyama M, Mori K, et al. Overexpression of connective tissue growth factor in podocytes worsens diabetic nephropathy in mice. Kidney Int 2008; 73: 446-455. (Pubitemid 351186294)
40. Yokoi H, Mukoyama M, Nagae T, et al. Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis. J Am Soc Nephrol 2004; 15: 1430-1440. (Pubitemid 38679668)
41. Yoshio Y, Miyazaki M, Abe K, et al. TNP-470, an angiogenesis inhibitor, suppresses the progression of peritoneal fibrosis in mouse experimental model. Kidney Int 2004; 66: 1677-1685. (Pubitemid 39298405)
42. Tamura M, Osajima A, Nakayamada S, et al. High glucose levels inhibit focal adhesion kinase-mediated wound healing of rat peritoneal mesothelial cells. Kidney Int 2003; 63: 722-731. (Pubitemid 36126820)
43. Yung S, Li FK, Chan TM. Peritoneal mesothelial cell culture and biology. Perit Dial Int 2006; 26: 162-173. (Pubitemid 44336164)
44. Suganami T, Mukoyama M, Sugawara A, et al. Overexpression of brain natriuretic peptide in mice ameliorates immune-mediated renal injury. J Am Soc Nephrol 2001; 12: 2652-2663. (Pubitemid 33115412)
45. Sawai K, Mori K, Mukoyama M, et al. Angiogenic protein Cyr61 is expressed by podocytes in anti-Thy-1 glomerulonephritis. J Am Soc Nephrol 2003; 14: 1154-1163. (Pubitemid 36514658)