Design and evaluation of mucoadhesive microspheres of repaglinide for oral controlled release

International Journal of Drug Delivery

Volumn 1, Issue 2, 2011, Pages 357-370

  Yadav, Vimal K ^a   Kumar, Brajesh ^a   Prajapati, S K ^a   shafaat, Kausar ^a  

^a BUNDELKHAND UNIVERSITY   (India)

Author keywords

Controlled Release; Microspheres; Mucoadhesive; Repaglinide; Solvent Evaporation

Indexed keywords

CHITOSAN; EUDRAGIT; GLUCOSE; MICROSPHERE; REPAGLINIDE; EUDRAGIT RS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG DESIGN; DRUG EFFICACY; EMULSION; EMULSION SOLVENT EVAPORATION; FEMALE; GLUCOSE BLOOD LEVEL; IN VITRO STUDY; MALE; MICROENCAPSULATION; MUCOADHESION; NONHUMAN; PARTICLE SIZE; RAT; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; CONTROLLED DRUG RELEASE; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG HALF LIFE; DRUG MECHANISM; DRUG SCREENING; GASTROINTESTINAL ABSORPTION; IN VIVO STUDY; SCANNING ELECTRON MICROSCOPY; SLOW DRUG RELEASE; SUSTAINED RELEASE FORMULATION; TIMED DRUG RELEASE;

EID: 84855205243     PISSN: None     EISSN: 09750215     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Prajapati SK, Tripathi P, Ubaidulla U, Anand V. Design and development of Gliclazide Mucoadhesive Microspheres: In Vitro and In Vivo Evaluation. AAPS PharmSci Tech.2006;6:224-230.
2. Mahor S, Palani S, Joseph NM, Garud N. Preparation and evaluation of Gastroretentive microspheres of ranitidine hydrochloride. Asian journal of Pharmaceutics 2007;1:164-169.
3. Akiyama Y, Nagahara N. Novel formulation approaches to oral mucoadhesive drug delivery systems. in: Mathiowitz E, Chickering III DE, Lehr CM, (Eds.), Bioadheive Drug Delivery Systems: Fundamentals, Novel Approaches and Development, Marcel Dekker, New York,1999;p.477-505.
4. Bakan JA, Microencapsulation. The theory and practice of Industrial pharmacy. Lachman IL, Liberman HA, 2nd ed. Varghese, Mumbai, India,1991;412-428.
5. Davis SN, Granner DK. Insulin, oral hypoglycemic agents and the pharmacology of the endocrine pancreas, in: Hardman JG, Limbrid LE. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 10th ed. McGraw-Hill Medica Publishing Division, USA.2001;1704-1705.
6. Chowdary KPR, Srinivas L. Mucoadhesive drug delivery systems: a status of current review. Indian Drugs 2000;37:400-406.
7. Gupta R, Prajapati SK, Bhardwaj HP. Formulation and evaluation of Glipizide floating microspheres. Asian journal of Pharmaceutics 2007;1:159-163.
8. Bogataj M, Mahor A, Korosec L. Influence of physicochemical and biological parameters on drug release from microspheres adhered on vesicle and intestinal mucosa. Int J Pharm. 1999;177:211-220.
9. Dhawan S, Singla AK, Sinha VR. Evaluation of Mucoadhesive Properties of Chitosan Microspheres. AAPS Journal 2004;5(4):1-7.
10. Jain SK, Awasthi AM, Jain NK, Agrawal GP. Calcium silicate based microspheres of Repaglinide for gastroretentive floating drug delivery: Preparation and in vitro characterization. J. Control Release 2005;107:300-309.
11. Mukhtar HM, Ansari SH, Ali M, Bhat ZA, Naved T. Effect of aqueous extract of Cyamopsis tetragonoloba linn. Beans on blood glucose level in normal and alloxan-induced diabetic rats. Indian J Exp Biol 2006;42:101-105.
12. Cuna M, Alonso MJ, Torres D. Preparation and in-vivo evaluation of mucoadhesive micro-particles containing Amoxicillin-resin complexes for drug delivery to the gastric mucosa. Eur J. Pharma Biopharma 2001;51:199-205.