Increasing recombinant protein production in Escherichia coli through metabolic and genetic engineering

Journal of Industrial Microbiology and Biotechnology

Volumn 38, Issue 12, 2011, Pages 1891-1910

  Waegeman, Hendrik ^a   Soetaert, Wim ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Biopharmaceutical; Engineering; Escherichia coli; Heterologous protein; Industrial enzyme; Recombinant protein production

Indexed keywords

ACETIC ACID; ALKALINE PHOSPHATASE; ALPHA INTERFERON; ASPARAGINASE; BACTERIOCIN; BETA ENDORPHIN; CARBOXYLESTERASE; DIHYDROLIPOAMIDE DEHYDROGENASE; ENDOSTATIN; ESCHERICHIA COLI PROTEIN; ESTERASE; GAMMA INTERFERON; GENOMIC DNA; HEAT SHOCK PROTEIN; HYBRID PROTEIN; HYDROXYNITRILE LYASE; IMMUNOGLOBULIN FC FRAGMENT; INDUSTRIAL ENZYME; INTERLEUKIN 7; LEPTIN; PHYTASE; PROINSULIN; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT PROTEIN; SOMATOMEDIN B; SOMATOMEDIN C; STREPTOKINASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ASPERGILLUS; BACILLUS MEGATERIUM; BACILLUS SUBTILIS; BACTERIAL STRAIN; BREVIBACILLUS BREVIS; CELL DENSITY; CELL STRAIN HEK293; CUPRIAVIDUS NECATOR; CYTOPLASM; ESCHERICHIA COLI; EXPRESSION VECTOR; FUNGAL STRAIN; GENETIC ENGINEERING; HOST; HUMAN; HYBRIDOMA; INSECT CELL; MAMMAL CELL; METABOLIC ENGINEERING; NONHUMAN; PICHIA PASTORIS; PLASMID; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PSEUDOMONAS PUTIDA; REVIEW; SACCHAROMYCES CEREVISIAE; TRICHODERMA;

BIOTECHNOLOGY; ESCHERICHIA COLI; GENETIC ENGINEERING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS;

ANIMALIA; BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; HEXAPODA; PICHIA PASTORIS; SACCHAROMYCES CEREVISIAE;

EID: 84855193592     PISSN: 13675435     EISSN: 14765535     Source Type: Journal    
DOI: 10.1007/s10295-011-1034-4     Document Type: Review

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