-
1
-
-
2342471392
-
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non-Small-Cell Lung Cancer to Gefitinib
-
DOI 10.1056/NEJMoa040938
-
TJ Lynch DW Bell R Sordella, et al. 2004 Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib New Engl J Med 350 2129 2139 15118073 10.1056/NEJMoa040938 1:CAS:528:DC%2BD2cXktF2js7c%3D (Pubitemid 38637993)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
2
-
-
2342624080
-
EGFR mutations in lung, cancer: Correlation with clinical response to gefitinib therapy
-
DOI 10.1126/science.1099314
-
JG Paez PA Janne JC Lee, et al. 2004 EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy Science 304 1497 1500 15118125 10.1126/science.1099314 1:CAS:528:DC%2BD2cXksVGmsbs%3D (Pubitemid 38720929)
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
Herman, P.7
Kaye, F.J.8
Lindeman, N.9
Boggon, T.J.10
Naoki, K.11
Sasaki, H.12
Fujii, Y.13
Eck, M.J.14
Sellers, W.R.15
Johnson, B.E.16
Meyerson, M.17
-
3
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
DOI 10.1073/pnas.0405220101
-
W Pao V Miller M Zakowski, et al. 2004 EGF receptor gene mutations are common in lung cancers from "never smokers", are associated with sensitivity of tumors to gefitinib, erlotinib Proc Natl Acad Sci USA 101 13306 13311 15329413 10.1073/pnas.0405220101 1:CAS:528:DC%2BD2cXnvFems70%3D (Pubitemid 39209661)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.36
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
Singh, B.7
Heelan, R.8
Rusch, V.9
Fulton, L.10
Mardis, E.11
Kupfer, D.12
Wilson, R.13
Kris, M.14
Varmus, H.15
-
4
-
-
19844375720
-
Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology
-
DOI 10.1200/JCO.2005.09.985
-
PA Janne JA Engelman BE Johnson 2005 Epidermal growth factor receptor mutations in non-small-cell lung cancer: implications for treatment, tumor biology J Clin Oncol 23 3227 3234 15886310 10.1200/JCO.2005.09.985 1:CAS:528:DC%2BD2MXltVWis70%3D (Pubitemid 46211347)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.14
, pp. 3227-3234
-
-
Janne, P.A.1
Engelman, J.A.2
Johnson, B.E.3
-
5
-
-
33746933434
-
Effect of epidermal growth factor receptor tyrosine kinase domain mutations on the outcome of patients with non-small cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors
-
DOI 10.1158/1078-0432.CCR-06-0555
-
PA Janne BE Johnson 2006 Effect of epidermal growth factor receptor tyrosine kinase domain mutations on the outcome of patients with non-small cell lung cancer treated with epidermal growth factor receptor tyrosine kinase inhibitors Clin Cancer Res 12 4416s 4420s 16857820 10.1158/1078-0432.CCR-06-0555 (Pubitemid 44197191)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.14
-
-
Janne, P.A.1
Johnson, B.E.2
Lynch, T.3
Bunn, P.4
Meyerson, M.5
Haber, D.6
Johnson, D.7
-
6
-
-
33645290760
-
Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking
-
16552419 10.1038/sj.bjc.6603040 1:CAS:528:DC%2BD28Xis1Gktbo%3D
-
K Sugio H Uramoto K Ono, et al. 2006 Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking Br J Cancer 94 896 903 16552419 10.1038/sj.bjc.6603040 1:CAS:528:DC%2BD28Xis1Gktbo%3D
-
(2006)
Br J Cancer
, vol.94
, pp. 896-903
-
-
Sugio, K.1
Uramoto, H.2
Ono, K.3
-
7
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
DOI 10.1056/NEJMoa044238
-
S Kobayashi TJ Boggon T Dayaram, et al. 2005 EGFR mutation, resistance of non-small-cell lung cancer to gefitinib New Engl J Med 352 786 792 15728811 10.1056/NEJMoa044238 1:CAS:528:DC%2BD2MXhsFCiurk%3D (Pubitemid 40271173)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.8
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
Janne, P.A.4
Kocher, O.5
Meyerson, M.6
Johnson, B.E.7
Eck, M.J.8
Tenen, D.G.9
Halmos, B.10
-
8
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
DOI 10.1126/science.1141478
-
JA Engelman K Zejnullahu T Mitsudomi, et al. 2007 MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling Science 316 1039 1043 17463250 10.1126/science.1141478 1:CAS:528:DC%2BD2sXltlOjt7g%3D (Pubitemid 46799492)
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Joon, O.P.6
Lindeman, N.7
Gale, C.-M.8
Zhao, X.9
Christensen, J.10
Kosaka, T.11
Holmes, A.J.12
Rogers, A.M.13
Cappuzzo, F.14
Mok, T.15
Lee, C.16
Johnson, B.E.17
Cantley, L.C.18
Janne, P.A.19
-
9
-
-
38049150665
-
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
-
18093943 10.1073/pnas.0710370104 1:CAS:528:DC%2BD1cXktlyhsg%3D%3D
-
J Bean C Brennan J-Y Shih, et al. 2007 MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib Proc Natl Acad Sci USA 104 20932 20937 18093943 10.1073/pnas.0710370104 1:CAS:528:DC%2BD1cXktlyhsg%3D%3D
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 20932-20937
-
-
Bean, J.1
Brennan, C.2
Shih, J.-Y.3
-
10
-
-
56449089812
-
Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations
-
19010923 10.1158/0008-5472.CAN-08-1643 1:CAS:528:DC%2BD1cXhtlOmt7jE
-
S Yano W Wang Q Li, et al. 2008 Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations Cancer Res 68 9479 9487 19010923 10.1158/0008-5472.CAN-08-1643 1:CAS:528:DC%2BD1cXhtlOmt7jE
-
(2008)
Cancer Res
, vol.68
, pp. 9479-9487
-
-
Yano, S.1
Wang, W.2
Li, Q.3
-
11
-
-
33745965856
-
High sensitivity detection of epidermal growth factor receptor mutations in the pleural effusion of non-small cell lung cancer patients
-
DOI 10.1111/j.1349-7006.2006.00216.x
-
H Kimura Y Fujiwara T Sone, et al. 2006 High sensitivity detection of epidermal growth factor receptor mutations in the pleural effusion of non-small cell lung cancer patients Cancer Sci 97 642 648 16827805 10.1111/j.1349-7006. 2006.00216.x 1:CAS:528:DC%2BD28XmsVOntLs%3D (Pubitemid 44056613)
-
(2006)
Cancer Science
, vol.97
, Issue.7
, pp. 642-648
-
-
Kimura, H.1
Fujiwara, Y.2
Sone, T.3
Kunitoh, H.4
Tamura, T.5
Kasahara, K.6
Nishio, K.7
-
12
-
-
34548593298
-
Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA)
-
DOI 10.1038/sj.bjc.6603949, PII 6603949
-
H Kimura M Suminoe K Kasahara, et al. 2007 Evaluation of epidermal growth factor receptor mutation status in serum DNA as a predictor of response to gefitinib (IRESSA) Br J Cancer 97 778 784 17848912 10.1038/sj.bjc.6603949 1:CAS:528:DC%2BD2sXhtVWksLzP (Pubitemid 47396294)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.6
, pp. 778-784
-
-
Kimura, H.1
Suminoe, M.2
Kasahara, K.3
Sone, T.4
Araya, T.5
Tamori, S.6
Koizumi, F.7
Nishio, K.8
Miyamoto, K.9
Fujimura, M.10
Nakao, S.11
-
13
-
-
0017785769
-
Primary bioassay of human tumor stem cells
-
560061 10.1126/science.560061 1:STN:280:DyaE2s3hsF2htA%3D%3D
-
A Hamburger S Salmon 1977 Primary bioassay of human tumor stem cells Science 197 461 463 560061 10.1126/science.560061 1:STN:280:DyaE2s3hsF2htA%3D%3D
-
(1977)
Science
, vol.197
, pp. 461-463
-
-
Hamburger, A.1
Salmon, S.2
-
14
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
DOI 10.1038/35102167
-
T Reya SJ Morrison MF Clarke, et al. 2001 Stem cells, cancer, cancer stem cells Nature 414 105 111 11689955 10.1038/35102167 1:CAS:528: DC%2BD3MXot1ahs7c%3D (Pubitemid 33041634)
-
(2001)
Nature
, vol.414
, Issue.6859
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
15
-
-
63849148757
-
Genetic heterogeneity of EGFR mutation in pleomorphic carcinoma of the lung: Response to gefitinib, clinical outcome
-
19155283 10.1093/jjco/hyn155
-
A Ushiki T Koizumi N Kobayashi, et al. 2009 Genetic heterogeneity of EGFR mutation in pleomorphic carcinoma of the lung: response to gefitinib, clinical outcome Jpn J Clin Oncol 39 267 270 19155283 10.1093/jjco/hyn155
-
(2009)
Jpn J Clin Oncol
, vol.39
, pp. 267-270
-
-
Ushiki, A.1
Koizumi, T.2
Kobayashi, N.3
-
16
-
-
77951009966
-
Pulmonary pleomorphic carcinoma: A clinicopathological study including EGFR mutation analysis
-
20107421 10.1097/JTO.0b013e3181ce3e3c
-
K Kaira Y Horie E Ayabe, et al. 2010 Pulmonary pleomorphic carcinoma: a clinicopathological study including EGFR mutation analysis J Thorac Oncol 5 460 465 20107421 10.1097/JTO.0b013e3181ce3e3c
-
(2010)
J Thorac Oncol
, vol.5
, pp. 460-465
-
-
Kaira, K.1
Horie, Y.2
Ayabe, E.3
-
17
-
-
33644502521
-
Mutations of epidermal growth factor receptor, K-ras genes in adenosquamous carcinoma of the lung
-
16187277 10.1002/ijc.21500 1:CAS:528:DC%2BD28XhslCqsbg%3D
-
S Toyooka Y Yatabe M Tokumo, et al. 2006 Mutations of epidermal growth factor receptor, K-ras genes in adenosquamous carcinoma of the lung Int J Cancer 118 1588 1590 16187277 10.1002/ijc.21500 1:CAS:528:DC%2BD28XhslCqsbg%3D
-
(2006)
Int J Cancer
, vol.118
, pp. 1588-1590
-
-
Toyooka, S.1
Yatabe, Y.2
Tokumo, M.3
-
18
-
-
58149149814
-
Epidermal growth factor receptor mutations in small cell lung cancer
-
18829487 10.1158/1078-0432.CCR-08-0332 1:CAS:528:DC%2BD1cXhtF2nurvM
-
A Tatematsu J Shimizu Y Murakami, et al. 2008 Epidermal growth factor receptor mutations in small cell lung cancer Clin Cancer Res 14 6092 6096 18829487 10.1158/1078-0432.CCR-08-0332 1:CAS:528:DC%2BD1cXhtF2nurvM
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6092-6096
-
-
Tatematsu, A.1
Shimizu, J.2
Murakami, Y.3
|