Bone scintigraphy in breast cancer: Added value of hybrid SPECT-CT and its impact on patient management

Nuclear Medicine Communications

Volumn 33, Issue 2, 2012, Pages 139-147

  Sharma, Punit ^a   Singh, Harmandeep ^a   Kumar, Rakesh ^a   Bal, Chandrasekhar ^a   Thulkar, Sanjay ^a   Seenu, Vulatheru ^a   Malhotra, Arun ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

bone metastasis; bone scintigraphy; breast cancer; SPECT; SPECT CT

Indexed keywords

MEDRONATE TECHNETIUM TC 99M;

ADULT; ARTICLE; BONE METASTASIS; BONE SCINTISCANNING; BREAST CANCER; CANCER PATIENT; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; METASTASIS; PATIENT CARE; PLANAR SCINTIGRAPHY; PREDICTIVE VALUE; RECALL BIAS; RETROSPECTIVE STUDY; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ADULT; BONE NEOPLASMS; BREAST NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TECHNETIUM TC 99M MEDRONATE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; WHOLE BODY IMAGING;

EID: 84855190124     PISSN: 01433636     EISSN: 14735628     Source Type: Journal    
DOI: 10.1097/MNM.0b013e32834e3b14     Document Type: Article

References (26)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E. Forman DCA. Global cancer statistics. Cancer J Clin 2011; 61:69-90.
2. Coleman RE, Rubens RD. The clinical course of bone metastases from breast cancer. Br J Cancer 1987; 55:61-66. (Pubitemid 17234155)
3. Cook GJ, Houston S, Rubens R, Maisey MN, Fogelman I. Detection of bone metastases in breast cancer by 18FDG PET: differing metabolic activity in osteoblastic and osteolytic lesions. J Clin Oncol 1998; 16:3375-3379. (Pubitemid 28481635)
4. Hamaoka T, Madewell JE, Podoloff DA, Hortobagyi GN, Ueno NT. Bone imaging in metastatic breast cancer. J Clin Oncol 2005; 22:2924-2953.
5. Even-Sapir E. Imaging of malignant bone involvement by morphologic, scintigraphic and hybrid modalities. J Nucl Med 2005; 46:1356-1367. (Pubitemid 43733488)
6. Blake GM, Park-Holohan SJ, Cook GJ, Fogelman I. Quantitative studies of bone with the use of 18F-fluoride and 99mTc-methylene diphosphonate. Semin Nucl Med 2001; 31:28-49. (Pubitemid 32060651)
7. Tryciecky EW, Gottschalk A, Ludema K. Oncologic imaging: interactions of nuclear medicine with CTand MRI using the one scan as the model. Semin Nucl Med 1997; 27:142-151. (Pubitemid 27194759)
8. Shie P, Cardarelli R, Brandon D, Erdman W, Abdulrahim N. Meta-analysis: comparison of F-18 flurodeoxyglucose-positron emission tomography and bone scintigraphy in the detection of bone metastases in patients with breast cancer. Clin Nucl Med 2007; 33:97-101.
9. Rybak LD, Rosenthal DI. Radiological imaging for the diagnosis of bone metastases. Q J Nucl Med 2001; 45:53-64. (Pubitemid 32586342)
10. Savelli G, Maffioli L, Maccauro M, De Deckere E, Bombardieri E. Bone scintigraphy and the added value of SPECT (single photon emission tomography) in detecting skeletal lesions. Q J Nucl Med 2001; 45:27-37. (Pubitemid 32586339)
11. Love C, Din AS, Tomas MB, Kalapparambath TP, Palestro CJ. Radionuclide bone imaging: an illustrative review. RadioGraphics 2003; 23:341-358. (Pubitemid 37431266)
12. Horger M, Bares R. The role of single photon emission computed tomography/computed tomography in benign and malignant bone disease. Semin Nucl Med 2006; 36:286-294. (Pubitemid 44300993)
13. Even-Sapir E, Martin RH, Barnes DC, Pringle CR, Iles SE, Mitchell MJ. Role of SPECT in differentiating malignant from benign lesions in the lower thoracic and lumbar vertebrae. Radiology 1993; 187:193-198. (Pubitemid 23097884)
14. Gates GF. SPECT bone scanning of the spine. Semin Nucl Med 1998; 28:78-94. (Pubitemid 28044991)
15. Reinartz P, Schaffeldt J, Sabri O, Zimny M, Nowak B, Ostwald E. Benign versus malignant osseous lesions in the lumbar vertebrae: differentiation by means of bone SPECT. Eur J Nucl Med 2000; 27:721-726. (Pubitemid 30408775)
16. Bocher M, Balan A, Krausz Y, Shrem Y, Lonn A, Wilk M. Gamma camera-mounted anatomical X-ray tomography: technology, system characteristics and first images. Eur J Nucl Med 2000; 27:619-627. (Pubitemid 30408762)
17. Townsend DW, Cherry SR. Combining anatomy and function: the path to true image fusion. Eur Radiol 2001; 11:1968-1974. (Pubitemid 32936900)
18. Schillaci O, Danieli R, Manni C, Simonetti G. Is SPECT/CT with a hybrid camera useful to improve scintigraphic imaging interpretation? Nucl Med Commun 2004; 25:705-710. (Pubitemid 38901688)
19. Utsunomiya D, Shiraishi S, Imuta M, Tomiguchi S, Kawanaka K, Morishita S. Added value of SPECT/CT fusion in assessing suspected bone metastasis: comparison with scintigraphy alone and nonfused scintigraphy and CT. Radiology 2006; 238:264-327.
20. Ndlovu X, George R, Ellmann A, Warwick J. Should SPECT-CT replace SPECT for the evaluation of equivocal bone scan lesions in patients with underlying malignancies? Nucl Med Commun 2010; 31:659-665.
21. Even-Sapir E, Metser U, Flusser G, Zuriel L, Kollender Y, Lerman H. Assessment of malignant skeletal disease: initial experience with 18F-fluoride PET/CT and comparison between18F-fluoride PET and 18F-fluoride PET/CT. J Nucl Med 2004; 45:272-278. (Pubitemid 47618648)
22. Metz CE. Basic principles of ROC analysis. Semin Nucl Med 1978; 8:283-298. (Pubitemid 9075026)
23. Yeh KA, Fortunato L, Ridge JA, Hoffman JP, Eisenberg BL, Sigurdson ER. Routine bone scanning in patients with T1 and T2 breast cancer: a waste of money. Ann Surg Oncol 1995; 2:319-324.
24. Römer W, Nömayr A, Uder M, Bautz W, Kuwert T. SPECT-Guided CT for evaluating foci of increased bone metabolism classified as indeterminate on SPECT in cancer patients. J Nucl Med 2006; 47:1102-1106. (Pubitemid 47544905)
25. Valentin J. Radiation dose to patients from radiopharmaceuticals (addendum 2 to ICRP publication 53). Ann ICRP 1998; 28:1-126.
26. Bristow AR, Agrawal A, Evans AJ, Burrell HC, Cornford EJ, James JJ, et al. Can computerised tomography replace bone scintigraphy in detecting bone metastases from breast cancer? A prospective study. Breast 2008; 17:98-103. (Pubitemid 351228794)