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Volumn 118, Issue 12, 2011, Pages 1691-1702

Continuous drug delivery in early- and late-stage Parkinson's disease as a strategy for avoiding dyskinesia induction and expression

Author keywords

CDD; CDS; Duodopa; Dyskinesia; L dopa; Rotigotine

Indexed keywords

APOMORPHINE; CABERGOLINE; CARBIDOPA; CARBIDOPA PLUS LEVODOPA; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA; LISURIDE; PERGOLIDE; POSTSYNAPTIC RECEPTOR; PRAMIPEXOLE; ROPINIROLE; ROTIGOTINE;

EID: 84855189322     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-011-0703-9     Document Type: Review
Times cited : (46)

References (93)
  • 5
    • 0026457051 scopus 로고
    • Continuous lisuride effects on central dopaminergic mechanisms in Parkinson's disease
    • 1471868 10.1002/ana.410320611 1:STN:280:DyaK3s7htFOjsA%3D%3D
    • F Baronti MM Mouradian Davis TL, et al. 1992 Continuous lisuride effects on central dopaminergic mechanisms in Parkinson's disease Ann Neurol 32 776 781 1471868 10.1002/ana.410320611 1:STN:280:DyaK3s7htFOjsA%3D%3D
    • (1992) Ann Neurol , vol.32 , pp. 776-781
    • Baronti, F.1    Mouradian, M.M.2    Davis, T.L.3
  • 6
    • 0028324501 scopus 로고
    • 2 receptor agonist, is efficacious in rat and monkey models of Parkinson's disease
    • Belluzzi JD, Domino EF, May JM et al (1994) N-0923, a selective dopamine D2 receptor agonist, is efficacious in rat and monkey models of Parkinson's disease. Mov Disord 9:147-154 (Pubitemid 24092329)
    • (1994) Movement Disorders , vol.9 , Issue.2 , pp. 147-154
    • Belluzzi, J.D.1    Domino, E.F.2    May, J.M.3    Bankiewicz, K.S.4    McAfee, D.A.5
  • 7
    • 13444273340 scopus 로고    scopus 로고
    • Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates
    • DOI 10.1016/j.expneurol.2004.11.013
    • F Bibbiani LC Costantini R Patel, et al. 2005 Continuous dopaminergic stimulation reduces risk of motor complications in parkinsonian primates Exp Neurol 192 73 78 15698620 10.1016/j.expneurol.2004.11.013 1:CAS:528: DC%2BD2MXhtVKgsr8%3D (Pubitemid 40208539)
    • (2005) Experimental Neurology , vol.192 , Issue.1 , pp. 73-78
    • Bibbiani, F.1    Costantini, L.C.2    Patel, R.3    Chase, T.N.4
  • 8
    • 0028835737 scopus 로고
    • Continuous administration decreases and pulsatile administration increases behavioral sensitivity to a novel dopamine D2 agonist (U-91356A) in MPTP-exposed monkeys
    • 7853204 1:CAS:528:DyaK2MXjs1OhtL0%3D
    • PJ Blanchet F Calon JC Martel, et al. 1995 Continuous administration decreases and pulsatile administration increases behavioral sensitivity to a novel dopamine D2 agonist (U-91356A) in MPTP-exposed monkeys J Pharmacol Exp Ther 272 854 859 7853204 1:CAS:528:DyaK2MXjs1OhtL0%3D
    • (1995) J Pharmacol Exp Ther , vol.272 , pp. 854-859
    • Blanchet, P.J.1    Calon, F.2    Martel, J.C.3
  • 9
    • 77958170723 scopus 로고    scopus 로고
    • Rotigotine transdermal patch for the treatment of Parkinson's disease and restless legs syndrome
    • 10.1358/dot.2010.46.7.1463530 1:STN:280:DC%2BC3cjisVKjsg%3D%3D
    • B Boroojerdi HM Wolff M Braun DK Scheller 2010 Rotigotine transdermal patch for the treatment of Parkinson's disease and restless legs syndrome Drugs Today (Barc) 46 7 483 505 10.1358/dot.2010.46.7.1463530 1:STN:280: DC%2BC3cjisVKjsg%3D%3D
    • (2010) Drugs Today (Barc) , vol.46 , Issue.7 , pp. 483-505
    • Boroojerdi, B.1    Wolff, H.M.2    Braun, M.3    Scheller, D.K.4
  • 10
    • 34547404736 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics of rotigotine in patients with early-stage Parkinson's disease
    • M Braun W Cawello K Poole, et al. 2005 Steady-state pharmacokinetics of rotigotine in patients with early-stage Parkinson's disease Eur J Neurol 12 S2 96
    • (2005) Eur J Neurol , vol.12 , Issue.S2 , pp. 96
    • Braun, M.1    Cawello, W.2    Poole, K.3
  • 11
    • 70349302129 scopus 로고    scopus 로고
    • Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: Administration by intravenous infusion or transdermal delivery
    • 19608695 10.1124/dmd.109.027383 1:CAS:528:DC%2BD1MXht1amsLnK
    • W Cawello M Braun H Boekens 2009 Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: administration by intravenous infusion or transdermal delivery Drug Metab Dispos 37 2055 2060 19608695 10.1124/dmd.109.027383 1:CAS:528:DC%2BD1MXht1amsLnK
    • (2009) Drug Metab Dispos , vol.37 , pp. 2055-2060
    • Cawello, W.1    Braun, M.2    Boekens, H.3
  • 12
    • 0031976069 scopus 로고    scopus 로고
    • The significance of continuous dopaminergic stimulation in the treatment of Parkinson's disease
    • TN Chase 1998 The significance of continuous dopaminergic stimulation in the treatment of Parkinson's disease Drugs 55 S1 1 9 9483164 10.2165/00003495-199855001-00001 (Pubitemid 28051032)
    • (1998) Drugs , vol.55 , Issue.SUPPL. 1 , pp. 1-9
    • Chase, T.N.1
  • 13
    • 0031923068 scopus 로고    scopus 로고
    • Continuous subcutaneous waking day apomorphine in the long term treatment of levodopa induced interdose dyskinesias in Parkinson's disease
    • A Colzi K Turner AJ Lees 1998 Continuous subcutaneous waking day apomorphine in the long term treatment of levodopa induced interdose dyskinesias in Parkinson's disease J Neurol Neurosurg Psychiatry 64 573 576 9598668 10.1136/jnnp.64.5.573 1:STN:280:DyaK1c3lvVKitw%3D%3D (Pubitemid 28204140)
    • (1998) Journal of Neurology Neurosurgery and Psychiatry , vol.64 , Issue.5 , pp. 573-576
    • Colzi, A.1    Turner, K.2    Lees, A.J.3
  • 14
    • 10344236071 scopus 로고    scopus 로고
    • Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: Implications for dyskinesias
    • DOI 10.1093/brain/awh290
    • R de la Fuente-Fernandez V Sossi, et al. 2004 Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias Brain 127 2747 2754 15329355 10.1093/brain/awh290 (Pubitemid 39627382)
    • (2004) Brain , vol.127 , Issue.12 , pp. 2747-2754
    • De La Fuente-Fernandez, R.1    Sossi, V.2    Huang, Z.3    Furtado, S.4    Lu, J.-Q.5    Calne, D.B.6    Ruth, T.J.7    Stoessl, A.J.8
  • 15
    • 0025630386 scopus 로고
    • Transdermal administration of the dopamine agonist N-0437 and seven ester prodrugs: Comparison with oral administration in the 6-OHDA turning model
    • den Daas I, Tepper PG, Rollema H et al (1990) Transdermal administration of the dopamine agonist N-0437 and seven ester prodrugs: comparison with oral administration in the 6-OHDA turning model. Naunyn Schmiedebergs Arch Pharmacol 342: 655-699
    • (1990) Naunyn Schmiedebergs Arch Pharmacol , vol.342 , pp. 655-699
    • Den Daas, I.1    Tepper, P.G.2    Rollema, H.3
  • 16
    • 67651165342 scopus 로고    scopus 로고
    • Patient profile, indications, efficacy and safety of duodenal levodopa infusion in advanced Parkinson's disease
    • French DUODOPA Study Group. 19253412 10.1002/mds.22450
    • D Devos French DUODOPA Study Group 2009 Patient profile, indications, efficacy and safety of duodenal levodopa infusion in advanced Parkinson's disease Mov Disord 24 993 1000 19253412 10.1002/mds.22450
    • (2009) Mov Disord , vol.24 , pp. 993-1000
    • Devos, D.1
  • 17
    • 44649127437 scopus 로고    scopus 로고
    • Continuous jejunal levodopa infusion in patients with advanced Parkinson disease: Practical aspects and outcome of motor and non-motor complications
    • DOI 10.1097/wnf.0b013e31814b113e, PII 0000282620080500000004
    • K Eggert C Schrader M Hahn, et al. 2008 Continuous jejunal levodopa infusion in patients with advanced Parkinson disease: practical aspects and outcome of motor and non-motor complications Clin Neuropharmacol 31 151 166 18520982 10.1097/wnf.0b013e31814b113e 1:CAS:528:DC%2BD1cXmsFylsr4%3D (Pubitemid 351787111)
    • (2008) Clinical Neuropharmacology , vol.31 , Issue.3 , pp. 151-166
    • Eggert, K.1    Schrader, C.2    Hahn, M.3    Stamelou, M.4    Russmann, A.5    Dengler, R.6    Oertel, W.7    Odin, P.8
  • 18
    • 38549159427 scopus 로고    scopus 로고
    • Rotigotine transdermal patch in early Parkinson's disease: A randomized, double-blind, controlled study versus placebo and ropinirole
    • DOI 10.1002/mds.21741
    • N Giladi B Boroojerdi AD Korczyn, et al. 2007 Rotigotine transdermal patch in early Parkinson's disease: a randomized, double-blind, controlled study versus placebo and ropinirole Mov Disord 22 2398 2404 17935234 10.1002/mds.21741 (Pubitemid 351155987)
    • (2007) Movement Disorders , vol.22 , Issue.16 , pp. 2398-2404
    • Giladi, N.1    Boroojerdi, B.2    Korczyn, A.D.3    Burn, D.J.4    Clarke, C.E.5    Schapira, A.H.V.6
  • 19
    • 84855193210 scopus 로고    scopus 로고
    • Effects of Long-Term Treatment with Rotigotine Transdermal Patch on Dyskinesias in Early-stage Parkinson's Disease (PD): Results from Two Open-Label Extension Trials
    • abs. P1113
    • Giladi N, Jankovic J, Watts RL et al (2010) Effects of Long-Term Treatment With Rotigotine Transdermal Patch on Dyskinesias in Early-stage Parkinson's Disease (PD): results from Two Open-Label Extension Trials. European Federation of Neurological Societies-14th Congress, Eur J Neurol 17(suppl 3):121, abs. P1113
    • (2010) European Federation of Neurological Societies-14th Congress, Eur J Neurol , vol.17 , Issue.SUPPL. 3 , pp. 121
    • Giladi, N.1    Jankovic, J.2    Watts, R.L.3
  • 20
    • 0037312540 scopus 로고    scopus 로고
    • Dopamine release during sequential finger movements in health and Parkinson's disease: A PET study
    • DOI 10.1093/brain/awg035
    • IK Goerendt C Messa AD Lawrence 2003 Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study Brain 126 312 325 12538400 10.1093/brain/awg035 (Pubitemid 36172738)
    • (2003) Brain , vol.126 , Issue.2 , pp. 312-325
    • Goerendt, I.K.1    Messa, C.2    Lawrence, A.D.3    Grasby, P.M.4    Piccini, P.5    Brooks, D.J.6
  • 21
    • 33846977067 scopus 로고    scopus 로고
    • Agonist-dependent internalization of D2 receptors: Imaging quantification by confocal microscopy
    • 17230553 10.1002/syn.20360 1:CAS:528:DC%2BD2sXhvFWjt7c%3D
    • JL Goggi A Sardini A Egerton, et al. 2007 Agonist-dependent internalization of D2 receptors: imaging quantification by confocal microscopy Synapse 61 231 241 17230553 10.1002/syn.20360 1:CAS:528:DC%2BD2sXhvFWjt7c%3D
    • (2007) Synapse , vol.61 , pp. 231-241
    • Goggi, J.L.1    Sardini, A.2    Egerton, A.3
  • 22
    • 34948819210 scopus 로고    scopus 로고
    • The Yin and Yang of dopamine release: A new perspective
    • DOI 10.1016/j.neuropharm.2007.07.007, PII S0028390807002171
    • Y Goto S Otani AA Grace 2007 The Yin and Yang of dopamine release: a new perspective Neuropharmacology 53 583 587 17709119 10.1016/j.neuropharm.2007.07. 007 1:CAS:528:DC%2BD2sXhtFekurbN (Pubitemid 47516678)
    • (2007) Neuropharmacology , vol.53 , Issue.5 , pp. 583-587
    • Goto, Y.1    Otani, S.2    Grace, A.A.3
  • 23
    • 0026059697 scopus 로고
    • Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia
    • 1676137 10.1016/0306-4522(91)90196-U 1:CAS:528:DyaK3MXisVGiur8%3D
    • AA Grace 1991 Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia Neuroscience 41 1 24 1676137 10.1016/0306-4522(91)90196-U 1:CAS:528: DyaK3MXisVGiur8%3D
    • (1991) Neuroscience , vol.41 , pp. 1-24
    • Grace, A.A.1
  • 24
    • 53149111568 scopus 로고    scopus 로고
    • Physiology of the normal and dopamine-depleted basal ganglia: Insights into levodopa pharmacotherapy
    • 10.1002/mds.22020
    • AA Grace 2008 Physiology of the normal and dopamine-depleted basal ganglia: insights into levodopa pharmacotherapy Mov Disord 23 S3 560 569 10.1002/mds.22020
    • (2008) Mov Disord , vol.23 , Issue.S3 , pp. 560-569
    • Grace, A.A.1
  • 25
    • 3142733662 scopus 로고    scopus 로고
    • Pramipexole vs levodopa as initial treatment for Parkinson Disease: A 4-year randomized controlled trial
    • DOI 10.1001/archneur.61.7.1044
    • RG Holloway I Shoulson S Fahn Parkinson Study Group, et al. 2004 Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial Arch Neurol 61 1044 1053 15262734 10.1001/archneur.61.7.1044 (Pubitemid 38915945)
    • (2004) Archives of Neurology , vol.61 , Issue.7 , pp. 1044-1053
    • Holloway, R.G.1
  • 26
    • 69849090592 scopus 로고    scopus 로고
    • Intrajejunal levodopa infusion in Parkinson's disease: A pilot multicenter study of effects on nonmotor symptoms and quality of life
    • 19425079 10.1002/mds.22596
    • H Honig A Antonini P Martinez-Martin, et al. 2009 Intrajejunal levodopa infusion in Parkinson's disease: a pilot multicenter study of effects on nonmotor symptoms and quality of life Mov Disord 24 1468 1474 19425079 10.1002/mds.22596
    • (2009) Mov Disord , vol.24 , pp. 1468-1474
    • Honig, H.1    Antonini, A.2    Martinez-Martin, P.3
  • 27
    • 55949085505 scopus 로고    scopus 로고
    • Fluctuating functions related to quality of life in advanced Parkinson disease: Effects of duodenal levodopa infusion
    • 18547273 10.1111/j.1600-0404.2008.01049.x 1:STN:280: DC%2BD1cjkvVeqtw%3D%3D
    • D Isacson K Bingefors IS Kristiansen, et al. 2008 Fluctuating functions related to quality of life in advanced Parkinson disease: effects of duodenal levodopa infusion Acta Neurol Scand 118 379 386 18547273 10.1111/j.1600-0404. 2008.01049.x 1:STN:280:DC%2BD1cjkvVeqtw%3D%3D
    • (2008) Acta Neurol Scand , vol.118 , pp. 379-386
    • Isacson, D.1    Bingefors, K.2    Kristiansen, I.S.3
  • 28
    • 33847315060 scopus 로고    scopus 로고
    • Decreased expression of l-dopa-induced dyskinesia by switching to ropinirole in MPTP-treated common marmosets
    • DOI 10.1016/j.expneurol.2006.10.005, PII S0014488606005905
    • MJ Jackson LA Smith G Al-Barghouthy, et al. 2007 Decreased expression of l-dopa-induced dyskinesia by switching to ropinirole in MPTP-treated common marmosets Exp Neurol 204 162 170 17113078 10.1016/j.expneurol.2006.10.005 1:CAS:528:DC%2BD2sXisVWnsb0%3D (Pubitemid 46330268)
    • (2007) Experimental Neurology , vol.204 , Issue.1 , pp. 162-170
    • Jackson, M.J.1    Smith, L.A.2    Al-Barghouthy, G.3    Rose, S.4    Jenner, P.5
  • 29
    • 0037269421 scopus 로고    scopus 로고
    • The contribution of the MPTP-treated primate model to the development of new treatment strategies for Parkinson's disease
    • DOI 10.1016/S1353-8020(02)00115-3, PII S1353802002001153
    • P Jenner 2003 The contribution of the MPTP-treated primate model to the development of new treatment strategies for Parkinson's disease Parkinsonism Relat Disord 9 131 137 12573867 10.1016/S1353-8020(02)00115-3 (Pubitemid 36173561)
    • (2003) Parkinsonism and Related Disorders , vol.9 , Issue.3 , pp. 131-137
    • Jenner, P.1
  • 30
    • 53149097346 scopus 로고    scopus 로고
    • Preventing and controlling dyskinesia in Parkinson's disease-A view of current knowledge and future opportunities
    • 10.1002/mds.22022
    • P Jenner 2008 Preventing and controlling dyskinesia in Parkinson's disease-a view of current knowledge and future opportunities Mov Disord 23 S3 585 598 10.1002/mds.22022
    • (2008) Mov Disord , vol.23 , Issue.S3 , pp. 585-598
    • Jenner, P.1
  • 31
    • 72649092503 scopus 로고    scopus 로고
    • From the MPTP-treated primate to the treatment of motor complications in Parkinson's disease
    • 10.1016/S1353-8020(09)70829-6
    • P Jenner 2009 From the MPTP-treated primate to the treatment of motor complications in Parkinson's disease Parkinsonism Relat Disord 15 S4 18 10.1016/S1353-8020(09)70829-6
    • (2009) Parkinsonism Relat Disord , vol.15 , Issue.S4 , pp. 18
    • Jenner, P.1
  • 32
    • 53049084186 scopus 로고    scopus 로고
    • InSPECT: Investigating the effect of short-term treatment with pramipexole or l-dopa on [123I] β-CIT and SPECT imaging
    • Jennings DL, Tabamo R, Seibyl JP et al (2007) InSPECT: investigating the effect of short-term treatment with pramipexole or l-dopa on [123I] β-CIT and SPECT imaging. Mov Disord 22(S16):143-144
    • (2007) Mov Disord , vol.22 , Issue.16 , pp. 143-144
    • Jennings, D.L.1    Tabamo, R.2    Seibyl, J.P.3
  • 34
    • 0023833155 scopus 로고
    • D-DOPA and L-DOPA similarly elevate brain dopamine and produce turning behavior in rats
    • DOI 10.1016/0006-8993(88)91176-6
    • F Karoum WJ Freed LW Chuang 1988 d-dopa and l-dopa similarly elevate brain dopamine and produce turning behavior in rats Brain Res 440 190 194 3129126 10.1016/0006-8993(88)91176-6 1:CAS:528:DyaL1cXht1Cns7k%3D (Pubitemid 18058590)
    • (1988) Brain Research , vol.440 , Issue.1 , pp. 190-194
    • Karoum, F.1    Freed, W.J.2    Chuang, L.-W.3    Cannon-Spoor, E.4    Wyatt, R.J.5    Costa, E.6
  • 36
    • 34547102981 scopus 로고    scopus 로고
    • Continuous delivery of rotigotine decreases extracellular dopamine suggesting continuous receptor stimulation
    • DOI 10.1007/s00702-007-0719-3
    • J Kehr XJ Hu M Goiny DK Scheller 2007 Continuous delivery of rotigotine decreases extracellular dopamine suggesting continuous receptor stimulation J Neural Transm 114 1027 1031 17431734 10.1007/s00702-007-0719-3 1:CAS:528:DC%2BD2sXotFWrtrw%3D (Pubitemid 47106455)
    • (2007) Journal of Neural Transmission , vol.114 , Issue.8 , pp. 1027-1031
    • Kehr, J.1    Hu, X.-J.2    Goiny, M.3    Scheller, D.K.A.4
  • 37
    • 70349913646 scopus 로고    scopus 로고
    • Short-term cost and health consequences of duodenal levodopa infusion in advanced Parkinson's disease in Sweden: An exploratory study
    • 19799471
    • IS Kristiansen K Bingefors D Nyholm, et al. 2009 Short-term cost and health consequences of duodenal levodopa infusion in advanced Parkinson's disease in Sweden: an exploratory study Appl Health Econ Health Policy 7 167 180 19799471
    • (2009) Appl Health Econ Health Policy , vol.7 , pp. 167-180
    • Kristiansen, I.S.1    Bingefors, K.2    Nyholm, D.3
  • 38
    • 0023938094 scopus 로고
    • Duodenal and gastric delivery of l-dopa in parkinsonism
    • 3408240 10.1002/ana.410230611 1:STN:280:DyaL1czgvVClsw%3D%3D
    • R Kurlan JG Nutt WR Woodward 1988 Duodenal and gastric delivery of l-dopa in parkinsonism Ann Neurol 23 589 595 3408240 10.1002/ana.410230611 1:STN:280:DyaL1czgvVClsw%3D%3D
    • (1988) Ann Neurol , vol.23 , pp. 589-595
    • Kurlan, R.1    Nutt, J.G.2    Woodward, W.R.3
  • 39
    • 0027518164 scopus 로고
    • Double-blind, placebo-controlled, crossover study of duodenal infusion of levodopa/carbidopa in Parkinson's disease patients with 'on-off' fluctuations
    • MC Kurth JW Tetrud CM Tanner, et al. 1993 Double-blind, placebo-controlled, crossover study of duodenal infusion of levodopa/carbidopa in Parkinson's disease patients with 'on-off' fluctuations Neurology 43 1698 1703 8414015 1:STN:280:DyaK2c%2FitVaruw%3D%3D (Pubitemid 23307938)
    • (1993) Neurology , vol.43 , Issue.9 , pp. 1698-1703
    • Kurth, M.C.1    Tetrud, J.W.2    Tanner, C.M.3    Irwin, I.4    Stebbins, G.T.5    Goetz, C.G.6    Langston, J.W.7
  • 40
    • 33748522433 scopus 로고    scopus 로고
    • A review of the receptor-binding and pharmacokinetic properties of dopamine agonists
    • DOI 10.1016/j.clinthera.2006.08.004, PII S0149291806001846
    • T Kvernmo S Hartter E Burger 2006 A review of the receptor-binding and pharmacokinetic properties of dopamine agonists Clin Ther 28 1065 1078 16982285 10.1016/j.clinthera.2006.08.004 1:CAS:528:DC%2BD28XhtVGmsrnO (Pubitemid 44374749)
    • (2006) Clinical Therapeutics , vol.28 , Issue.8 , pp. 1065-1078
    • Kvernmo, T.1    Hartter, S.2    Burger, E.3
  • 41
    • 34247208187 scopus 로고    scopus 로고
    • Advanced Parkinson disease treated with rotigotine transdermal system: PREFER Study
    • DOI 10.1212/01.wnl.0000259516.61938.bb, PII 0000611420070417000008
    • PA LeWitt KE Lyons R Pahwa 2007 Advanced Parkinson disease treated with rotigotine transdermal system: PREFER Study Neurology 68 16 1262 1267 17438216 10.1212/01.wnl.0000259516.61938.bb 1:CAS:528:DC%2BD2sXktFOntLg%3D (Pubitemid 46625971)
    • (2007) Neurology , vol.68 , Issue.16 , pp. 1262-1267
    • LeWitt, P.A.1    Lyons, K.E.2    Pahwa, R.3
  • 42
    • 77349086589 scopus 로고    scopus 로고
    • L-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson's disease: Temporal and quantitative relationship to the expression of dyskinesia
    • 20050978 10.1111/j.1471-4159.2009.06556.x 1:CAS:528:DC%2BC3cXjsFaku7o%3D
    • HS Lindgren DR Andersson S Lagerkvist, et al. 2010 l-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson's disease: temporal and quantitative relationship to the expression of dyskinesia J Neurochem 112 1465 1476 20050978 10.1111/j.1471-4159.2009.06556.x 1:CAS:528:DC%2BC3cXjsFaku7o%3D
    • (2010) J Neurochem , vol.112 , pp. 1465-1476
    • Lindgren, H.S.1    Andersson, D.R.2    Lagerkvist, S.3
  • 44
    • 0026440079 scopus 로고
    • Motor activity following the administration of selective D-1 and D-2 dopaminergic drugs to MPTP-treated common marmosets
    • Loeschmann PA, Smith LA, Lange KW et al (1992) Motor activity following the administration of selective D-1 and D-2 dopaminergic drugs to MPTP-treated common marmosets. Psychopharmacology (Berl) 109:49-56
    • (1992) Psychopharmacology (Berl) , vol.109 , pp. 49-56
    • Loeschmann, P.A.1    Smith, L.A.2    Lange, K.W.3
  • 45
    • 54249107164 scopus 로고    scopus 로고
    • Thorough QT/QTc study in patients with advanced Parkinson's disease: Cardiac safety of rotigotine
    • 18650802 10.1038/clpt.2008.143 1:CAS:528:DC%2BD1cXht1OisLvI
    • M Malik JO Andreas K Hnatkova, et al. 2008 Thorough QT/QTc study in patients with advanced Parkinson's disease: cardiac safety of rotigotine Clin Pharmacol Ther 84 595 603 18650802 10.1038/clpt.2008.143 1:CAS:528: DC%2BD1cXht1OisLvI
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 595-603
    • Malik, M.1    Andreas, J.O.2    Hnatkova, K.3
  • 46
    • 0035125765 scopus 로고    scopus 로고
    • Intravenous apomorphine therapy in Parkinson's disease clinical and pharmacokinetic observations
    • AJ Manson H Hanagasi K Turner, et al. 2001 Intravenous apomorphine therapy in Parkinson's disease: clinical and pharmacokinetic observations Brain 124 331 340 11157560 10.1093/brain/124.2.331 1:STN:280:DC%2BD3M7ls1Ogtg%3D%3D (Pubitemid 32142405)
    • (2001) Brain , vol.124 , Issue.2 , pp. 331-340
    • Manson, A.J.1    Hanagasi, H.2    Turner, K.3    Patsalos, P.N.4    Carey, P.5    Ratnaraj, N.6    Lees, A.J.7
  • 47
    • 0035412883 scopus 로고    scopus 로고
    • Antiparkinsonian activity and dyskinesia risk of ropinirole and L-DOPA combination therapy in drug naïve MPTP-lesioned common marmosets (Callithrix jacchus)
    • DOI 10.1002/mds.1149
    • EC Maratos MJ Jackson RK Pearce, et al. 2001 Antiparkinsonian activity and dyskinesia risk of ropinirole and L-DOPA combination therapy in drug naive MPTP-lesioned common marmosets (Callithrix jacchus) Mov Disord 16 631 641 11481686 10.1002/mds.1149 1:STN:280:DC%2BD3Mvjtlyksw%3D%3D (Pubitemid 36040842)
    • (2001) Movement Disorders , vol.16 , Issue.4 , pp. 631-641
    • Maratos, E.C.1    Jackson, M.J.2    Pearce, R.K.B.3    Jenner, P.4
  • 48
    • 0037225230 scopus 로고    scopus 로고
    • Both short- and long-acting D-1/D-2 dopamine agonists induce less dyskinesia than L-DOPA in the MPTP-lesioned common marmoset (Callithrix jacchus)
    • DOI 10.1006/exnr.2002.8055
    • EC Maratos MJ Jackson RK Pearce, et al. 2003 Both short- and long-acting D-1/D-2 dopamine agonists induce less dyskinesia than l-DOPA in the MPTP-lesioned common marmoset (Callithrix jacchus) Exp Neurol 179 90 102 12504871 10.1006/exnr.2002.8055 1:CAS:528:DC%2BD38Xps12ku7Y%3D (Pubitemid 36062622)
    • (2003) Experimental Neurology , vol.179 , Issue.1 , pp. 90-102
    • Maratos, E.C.1    Jackson, M.J.2    Pearce, R.K.B.3    Cannizzaro, C.4    Jenner, P.5
  • 49
    • 0022608793 scopus 로고
    • Repeated levodopa infusions in fluctuating Parkinson's disease: Clinical and pharmacokinetic data
    • MH Marion F Stocchi NP Quinn, et al. 1986 Repeated levodopa infusions in fluctuating Parkinson's disease: clinical and pharmacokinetic data Clin Neuropharmacol 9 165 181 3708602 10.1097/00002826-198604000-00008 1:STN:280:DyaL283hslyhsA%3D%3D (Pubitemid 16111367)
    • (1986) Clinical Neuropharmacology , vol.9 , Issue.2 , pp. 165-181
    • Marion, M.H.1    Stocchi, F.2    Quinn, N.P.3
  • 50
    • 0033054705 scopus 로고    scopus 로고
    • Role of high-affinity dopamine uptake and impulse activity in the appearance of extracellular dopamine in striatum after administration of exogenous L-DOPA: Studies in intact and 6-hydroxydopamine-treated rats
    • DOI 10.1046/j.1471-4159.1999.721516.x
    • DW Miller ED Abercrombie 1999 Role of high-affinity dopamine uptake and impulse activity in the appearance of extracellular dopamine in striatum after administration of exogenous l-DOPA: studies in intact and 6-hydroxydopamine- treated rats J Neurochem 72 1516 1522 10098856 10.1046/j.1471-4159.1999.721516.x 1:CAS:528:DyaK1MXitFCksL0%3D (Pubitemid 29140823)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.4 , pp. 1516-1522
    • Miller, D.W.1    Abercrombie, E.D.2
  • 51
    • 0030722477 scopus 로고    scopus 로고
    • 2 agonist U91356A in continuous or intermittent mode of administration: Comparison with L-DOPA therapy
    • DOI 10.1016/S0169-328X(97)00123-X, PII S0169328X9700123X
    • M Morissette M Goulet JJ Soghomonian, et al. 1997 Preproenkephalin mRNA expression in the caudate-putamen of MPTP monkeys after chronic treatment with the D2 agonist U91356A in continuous or intermittent mode of administration: comparison with l-DOPA therapy Brain Res Mol Brain Res 49 55 62 9387863 10.1016/S0169-328X(97)00123-X 1:CAS:528:DyaK2sXlsleqtLk%3D (Pubitemid 27453114)
    • (1997) Molecular Brain Research , vol.49 , Issue.1-2 , pp. 55-62
    • Morissette, M.1    Goulet, M.2    Soghomonian, J.-J.3    Blanchet, P.J.4    Calon, F.5    Bedard, P.J.6    Di Paolo, T.7
  • 52
    • 0025129116 scopus 로고
    • Modification of central dopaminergic mechanisms by continuous levodopa therapy for advanced Parkinson's disease
    • DOI 10.1002/ana.410270105
    • MM Mouradian IJ Heuser F Baronti, et al. 1990 Modification of central dopaminergic mechanisms by continuous levodopa therapy for advanced Parkinson's disease Ann Neurol 27 18123 10.1002/ana.410270105 (Pubitemid 20031354)
    • (1990) Annals of Neurology , vol.27 , Issue.1 , pp. 18-23
    • Mouradian, M.M.1    Heuser, I.J.E.2    Baronti, F.3    Chase, T.N.4
  • 53
    • 0015043830 scopus 로고
    • L-dopa therapy of Parkinson's disease: Plasma l-dopa concentration, therapeutic response, and side effects
    • 5573818 1:STN:280:DyaE3M7osVSrsQ%3D%3D
    • MD Muenter GM Tyce 1971 l-dopa therapy of Parkinson's disease: plasma l-dopa concentration, therapeutic response, and side effects Mayo Clin Proc 46 231 239 5573818 1:STN:280:DyaE3M7osVSrsQ%3D%3D
    • (1971) Mayo Clin Proc , vol.46 , pp. 231-239
    • Muenter, M.D.1    Tyce, G.M.2
  • 54
    • 0031780594 scopus 로고    scopus 로고
    • Long-term intraduodenal infusion of a water based levodopa-carbidopa dispersion in very advanced Parkinson's disease
    • D Nilsson LE Hansson K Johansson, et al. 1998 Long-term intraduodenal infusion of a water based levodopa-carbidopa dispersion in very advanced Parkinson's disease Acta Neurol Scand 97 175 183 9531434 10.1111/j.1600-0404. 1998.tb00633.x 1:CAS:528:DyaK1cXhslGisLo%3D (Pubitemid 28254914)
    • (1998) Acta Neurologica Scandinavica , vol.97 , Issue.3 , pp. 175-183
    • Nilsson, D.1    Hansson, L.-E.2    Johansson, K.3    Nystrom, C.4    Paalzow, L.5    Aquilonius, S.-M.6
  • 55
    • 0035200697 scopus 로고    scopus 로고
    • Duodenal levodopa infusion in Parkinson's disease - Long-term experience
    • DOI 10.1034/j.1600-0404.2001.00153.x
    • D Nilsson D Nyholm SM Aquilonius 2001 Duodenal levodopa infusion in Parkinson's disease-long-term experience Acta Neurol Scand 104 343 348 11903087 10.1034/j.1600-0404.2001.00153.x 1:CAS:528:DC%2BD38XhsVehsA%3D%3D (Pubitemid 33107378)
    • (2001) Acta Neurologica Scandinavica , vol.104 , Issue.6 , pp. 343-348
    • Nilsson, D.1    Nyholm, D.2    Aquilonius, S.-M.3
  • 56
    • 0030914778 scopus 로고    scopus 로고
    • Motor fluctuations during continuous levodopa infusions in patients with Parkinson's disease
    • DOI 10.1002/mds.870120304
    • JG Nutt JH Carter ES Lea, et al. 1997 Motor fluctuations during continuous levodopa infusions in patients with Parkinson's disease Mov Disord 12 285 292 9159720 10.1002/mds.870120304 1:STN:280:DyaK2szgtleqtw%3D%3D (Pubitemid 27216124)
    • (1997) Movement Disorders , vol.12 , Issue.3 , pp. 285-292
    • Nutt, J.G.1    Carter, J.H.2    Lea, E.S.3    Woodward, W.R.4
  • 57
    • 0033696872 scopus 로고    scopus 로고
    • Continuous dopamine-receptor stimulation in advanced Parkinson's disease
    • 10.1016/S1471-1931(00)00029-X
    • JG Nutt JA Obeso F Stocchi 2000 Continuous dopamine-receptor stimulation in advanced Parkinson's disease Trends Neurosci 23 10 S 109 115 10.1016/S1471-1931(00)00029-X
    • (2000) Trends Neurosci , vol.23 , Issue.10 , pp. 109-115
    • Nutt, J.G.1    Obeso, J.A.2    Stocchi, F.3
  • 59
    • 12544252127 scopus 로고    scopus 로고
    • Duodenal l-dopa infusion monotherapy vs oral polypharmacy in advanced Parkinson disease
    • 15668416 10.1212/01.WNL.0000149637.70961.4C 1:STN:280: DC%2BD2M%2FktFSnsQ%3D%3D
    • D Nyholm AI Nilsson Remahl N Dizdar 2005 Duodenal l-dopa infusion monotherapy vs oral polypharmacy in advanced Parkinson disease Neurology 64 216 223 15668416 10.1212/01.WNL.0000149637.70961.4C 1:STN:280: DC%2BD2M%2FktFSnsQ%3D%3D
    • (2005) Neurology , vol.64 , pp. 216-223
    • Nyholm, D.1    Nilsson Remahl, A.I.2    Dizdar, N.3
  • 60
    • 41749084435 scopus 로고    scopus 로고
    • Enteral levodopa/carbidopa infusion in advanced Parkinson disease: Long-term exposure
    • DOI 10.1097/WNF.0b013e3180ed449f, PII 0000282620080300000001
    • D Nyholm T Lewander A Johansson, et al. 2008 Enteral levodopa/carbidopa infusion in advanced Parkinson disease: long-term exposure Clin Neuropharmacol 2008 31 63 73 10.1097/WNF.0b013e3180ed449f (Pubitemid 351489331)
    • (2008) Clinical Neuropharmacology , vol.31 , Issue.2 , pp. 63-73
    • Nyholm, D.1    Lewander, T.2    Johansson, A.3    LeWitt, P.A.4    Lundqvist, C.5    Aquilonius, S.-M.6
  • 61
    • 33645543539 scopus 로고    scopus 로고
    • Pergolide versus levodopa monotherapy in early Parkinson's disease patients: The PELMOPET study
    • 16211594 10.1002/mds.20724
    • WH Oertel E Wolters C Sampaio, et al. 2006 Pergolide versus levodopa monotherapy in early Parkinson's disease patients: the PELMOPET study Mov Disord 21 343 353 16211594 10.1002/mds.20724
    • (2006) Mov Disord , vol.21 , pp. 343-353
    • Oertel, W.H.1    Wolters, E.2    Sampaio, C.3
  • 62
    • 66949117423 scopus 로고    scopus 로고
    • The scientific and clinical basis for the treatment of Parkinson disease
    • 10.1212/WNL.0b013e3181a1d44c
    • CW Olanow MB Stern K Sethi 2009 The scientific and clinical basis for the treatment of Parkinson disease Neurology 72 1 136 10.1212/WNL.0b013e3181a1d44c
    • (2009) Neurology , vol.72 , pp. 1-136
    • Olanow, C.W.1    Stern, M.B.2    Sethi, K.3
  • 65
    • 0346754905 scopus 로고    scopus 로고
    • A Controlled Trial of Rotigotine Monotherapy in Early Parkinson's Disease
    • DOI 10.1001/archneur.60.12.1721
    • Parkinson Study Group 2003 A controlled trial of rotigotine monotherapy in early Parkinson's disease Arch Neurol 60 1721 1728 10.1001/archneur.60.12. 1721 (Pubitemid 37521625)
    • (2003) Archives of Neurology , vol.60 , Issue.12 , pp. 1721-1728
    • Blindeauer, K.1
  • 66
    • 0031930772 scopus 로고    scopus 로고
    • De novo administration of ropinirole and bromocriptine induces less dyskinesia than L-Dopa in the MPTP-treated marmoset
    • DOI 10.1002/mds.870130207
    • RK Pearce T Banerji Jenner P, et al. 1998 De novo administration of ropinirole and bromocriptine induces less dyskinesia than l-dopa in the MPTP-treated marmoset Mov Disord 13 234 241 9539335 10.1002/mds.870130207 1:STN:280:DyaK1c7pvVOnsw%3D%3D (Pubitemid 28127797)
    • (1998) Movement Disorders , vol.13 , Issue.2 , pp. 234-241
    • Pearce, R.K.B.1    Banerji, T.2    Jenner, P.3    Marsden, C.D.4
  • 68
    • 34248372064 scopus 로고    scopus 로고
    • Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: A double-blind, double-dummy, randomised controlled trial
    • DOI 10.1016/S1474-4422(07)70108-4, PII S1474442207701084
    • WH Poewe O Rascol N Quinn, et al. 2007 Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: A double-blind, double-dummy, randomised controlled trial Lancet Neurol 6 6 513 520 17509486 10.1016/S1474-4422(07)70108-4 1:CAS:528:DC%2BD2sXmslKktr8%3D (Pubitemid 46734759)
    • (2007) Lancet Neurology , vol.6 , Issue.6 , pp. 513-520
    • Poewe, W.H.1    Rascol, O.2    Quinn, N.3    Tolosa, E.4    Oertel, W.H.5    Martignoni, E.6    Rupp, M.7    Boroojerdi, B.8
  • 69
    • 4243794421 scopus 로고    scopus 로고
    • A multicenter, double-blind, randomized, placebo-controlled safety and efficacy study of rotigotine constant delivery system (CDS) in patients with advanced Parkinson's disease
    • N Quinn 2001 A multicenter, double-blind, randomized, placebo-controlled safety and efficacy study of rotigotine constant delivery system (CDS) in patients with advanced Parkinson's disease Parkinsonism Rel Disord 7 S1 S66
    • (2001) Parkinsonism Rel Disord , vol.7 , Issue.S1 , pp. 66
    • Quinn, N.1
  • 70
    • 0021211101 scopus 로고
    • Control of on/off phenomenon by continuous intravenous infusion of levodopa
    • N Quinn JD Parkes CD Marsden 1984 Control of on/off phenomenon by continuous intravenous infusion of levodopa Neurology 34 1131 1136 6540399 1:STN:280:DyaL2c3ntFWqtA%3D%3D (Pubitemid 14068582)
    • (1984) Neurology , vol.34 , Issue.9 , pp. 1131-1136
    • Quinn, N.1    Parkes, J.D.2    Marsden, C.D.3
  • 71
    • 33845531563 scopus 로고    scopus 로고
    • Parkinson's disease: Diagnosis and treatment
    • SS Rao LA Hofmann A Shakil 2006 Parkinson's disease: diagnosis and treatment Am Fam Phys 74 12 2046 2054
    • (2006) Am Fam Phys , vol.74 , Issue.12 , pp. 2046-2054
    • Rao, S.S.1    Hofmann, L.A.2    Shakil, A.3
  • 72
    • 0034682308 scopus 로고    scopus 로고
    • A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa
    • DOI 10.1056/NEJM200005183422004
    • O Rascol DJ Brooks AD Korczyn, et al. 2000 A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. 056 Study Group N Engl J Med 342 1484 1491 10816186 10.1056/NEJM200005183422004 1:CAS:528:DC%2BD3cXjvVeitrc%3D (Pubitemid 30318272)
    • (2000) New England Journal of Medicine , vol.342 , Issue.20 , pp. 1484-1491
    • Rascol, O.1    Brooks, D.J.2    Korczyn, A.D.3    De Deyn, P.P.4    Clarke, C.E.5    Lang, A.E.6
  • 74
    • 0031985731 scopus 로고    scopus 로고
    • Early treatment of Parkinson's disease with cabergoline delays the onset of motor complications. Results of a double-blind levodopa controlled trial
    • DOI 10.2165/00003495-199855001-00004
    • UK Rinne F Bracco C Chouza, et al. 1998 Early treatment of Parkinson's disease with cabergoline delays the onset of motor complications. Results of a double-blind levodopa controlled trial. The PKDS009 Study Group Drugs 55 S1 23 30 9483167 10.2165/00003495-199855001-00004 1:CAS:528:DyaK1cXhtVGjsr4%3D (Pubitemid 28051035)
    • (1998) Drugs , vol.55 , Issue.SUPPL. 1 , pp. 23-30
    • Rinne, U.K.1    Bracco, F.2    Chouza, C.3    Dupont, E.4    Gershanik, O.5    Marti Masso, J.F.6    Montastruc, J.L.7    Marsden, C.D.8
  • 75
    • 7044233123 scopus 로고    scopus 로고
    • The two faces of Eve: Dopamine's modulation of wakefulness and sleep
    • DB Rye 2004 The two faces of Eve: dopamine's modulation of wakefulness and sleep Neurology 63 8,S3 2 7
    • (2004) Neurology , vol.63 , Issue.8 S3 , pp. 2-7
    • Rye, D.B.1
  • 76
    • 0023937322 scopus 로고
    • Long-term duodenal infusion of levodopa for motor fluctuations in parkinsonism
    • 3415201 10.1002/ana.410240116 1:STN:280:DyaL1czisFejsA%3D%3D
    • JI Sage S Trooskin PK Sonsalla, et al. 1988 Long-term duodenal infusion of levodopa for motor fluctuations in parkinsonism Ann Neurol 24 87 89 3415201 10.1002/ana.410240116 1:STN:280:DyaL1czisFejsA%3D%3D
    • (1988) Ann Neurol , vol.24 , pp. 87-89
    • Sage, J.I.1    Trooskin, S.2    Sonsalla, P.K.3
  • 77
    • 0347133331 scopus 로고    scopus 로고
    • Neuroprotection in Parkinson Disease: Mysteries, Myths, and Misconceptions
    • DOI 10.1001/jama.291.3.358
    • AH Schapira CW Olanow 2004 Neuroprotection in Parkinson disease: mysteries, myths, and misconceptions JAMA 291 358 364 14734599 10.1001/jama.291.3.358 1:CAS:528:DC%2BD2cXmtlelsg%3D%3D (Pubitemid 38101609)
    • (2004) Journal of the American Medical Association , vol.291 , Issue.3 , pp. 358-364
    • Schapira, A.H.V.1    Olanow, C.W.2
  • 78
    • 59449110327 scopus 로고    scopus 로고
    • The in vitro receptor profile of rotigotine: A new agent for the treatment of Parkinson's disease
    • 18704368 10.1007/s00210-008-0341-4 1:CAS:528:DC%2BD1MXhtlOjsbk%3D
    • D Scheller C Ullmer R Berkels, et al. 2009 The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease Naunyn Schmiedebergs Arch Pharmacol 379 73 86 18704368 10.1007/s00210-008-0341-4 1:CAS:528:DC%2BD1MXhtlOjsbk%3D
    • (2009) Naunyn Schmiedebergs Arch Pharmacol , vol.379 , pp. 73-86
    • Scheller, D.1    Ullmer, C.2    Berkels, R.3
  • 79
    • 52449089646 scopus 로고    scopus 로고
    • Continuous versus pulsatile administration of rotigotine in 6-OHDA-lesioned rats: Contralateral rotations and abnormal involuntary movements
    • 18726139 10.1007/s00702-008-0102-z 1:CAS:528:DC%2BD1cXhtFensbfP
    • WJ Schmidt H Lebsanft M Heindl, et al. 2008 Continuous versus pulsatile administration of rotigotine in 6-OHDA-lesioned rats: contralateral rotations and abnormal involuntary movements J Neural Transm 115 1385 1392 18726139 10.1007/s00702-008-0102-z 1:CAS:528:DC%2BD1cXhtFensbfP
    • (2008) J Neural Transm , vol.115 , pp. 1385-1392
    • Schmidt, W.J.1    Lebsanft, H.2    Heindl, M.3
  • 80
    • 0027171165 scopus 로고
    • Suppression of dyskinesias in advanced Parkinson's disease. I. Continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease
    • LA Schuh JP Bennett Jr 1993 Suppression of dyskinesias in advanced Parkinson's disease. I. Continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease Neurology 43 1545 1550 8351009 1:STN:280: DyaK3szlsVGlug%3D%3D (Pubitemid 23230540)
    • (1993) Neurology , vol.43 , Issue.8 , pp. 1545-1550
    • Schuh, L.A.1    Bennett Jr., J.P.2
  • 81
    • 0028061519 scopus 로고
    • Behavior-related activity of primate dopamine neurons
    • W Schultz 1994 Behavior-related activity of primate dopamine neurons Rev Neurol (Paris) 150 634 639 1:STN:280:DyaK2M3ntlyrug%3D%3D (Pubitemid 24332154)
    • (1994) Revue Neurologique , vol.150 , Issue.8-9 , pp. 634-639
    • Schultz, W.1
  • 82
    • 49449109652 scopus 로고    scopus 로고
    • Dichotomous dopaminergic control of striatal synaptic plasticity
    • 18687967 10.1126/science.1160575 1:CAS:528:DC%2BD1cXptlyhsLw%3D
    • W Shen M Flajolet P Greengard, et al. 2008 Dichotomous dopaminergic control of striatal synaptic plasticity Science 321 848 851 18687967 10.1126/science.1160575 1:CAS:528:DC%2BD1cXptlyhsLw%3D
    • (2008) Science , vol.321 , pp. 848-851
    • Shen, W.1    Flajolet, M.2    Greengard, P.3
  • 83
    • 65449143957 scopus 로고    scopus 로고
    • Use of apomorphine in Parkinson's disease
    • Stocchi F (2008) Use of apomorphine in Parkinson's disease. Neurol Sci 29:S383-386
    • (2008) Neurol Sci , vol.29
    • Stocchi, F.1
  • 84
    • 0036723589 scopus 로고    scopus 로고
    • Prospective randomized trial of lisuride infusion versus oral levodopa in patients with Parkinson's disease
    • 12183351 10.1093/brain/awf214
    • F Stocchi S Ruggieri L Vacca, et al. 2002 Prospective randomized trial of lisuride infusion versus oral levodopa in patients with Parkinson's disease Brain 125 2058 2066 12183351 10.1093/brain/awf214
    • (2002) Brain , vol.125 , pp. 2058-2066
    • Stocchi, F.1    Ruggieri, S.2    Vacca, L.3
  • 85
    • 20844454214 scopus 로고    scopus 로고
    • Intermittent vs continuous levodopa administration in patients with advanced Parkinson disease: A clinical and pharmacokinetic study
    • DOI 10.1001/archneur.62.6.905
    • F Stocchi L Vacca S Ruggieri, et al. 2005 Intermittent vs continuous levodopa administration in patients with advanced Parkinson disease: a clinical and pharmacokinetic study Arch Neurol 62 905 910 15956161 10.1001/archneur.62.6. 905 (Pubitemid 40973452)
    • (2005) Archives of Neurology , vol.62 , Issue.6 , pp. 905-910
    • Stocchi, F.1    Vacca, L.2    Ruggieri, S.3    Olanow, C.W.4
  • 86
    • 77954043228 scopus 로고    scopus 로고
    • Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: The STRIDE-PD study
    • 20582993 10.1002/ana.22060 1:CAS:528:DC%2BC3cXpslagsrk%3D
    • F Stocchi O Rascol K Kieburtz, et al. 2010 Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study Ann Neurol 68 18 27 20582993 10.1002/ana.22060 1:CAS:528: DC%2BC3cXpslagsrk%3D
    • (2010) Ann Neurol , vol.68 , pp. 18-27
    • Stocchi, F.1    Rascol, O.2    Kieburtz, K.3
  • 87
    • 69949101386 scopus 로고    scopus 로고
    • Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction
    • 19619533 10.1016/j.expneurol.2009.07.011 1:CAS:528:DC%2BD1MXhtFajs7vM
    • KA Stockwell D Scheller S Rose, et al. 2009 Continuous administration of rotigotine to MPTP-treated common marmosets enhances anti-parkinsonian activity and reduces dyskinesia induction Exp Neurol 219 533 542 19619533 10.1016/j.expneurol.2009.07.011 1:CAS:528:DC%2BD1MXhtFajs7vM
    • (2009) Exp Neurol , vol.219 , pp. 533-542
    • Stockwell, K.A.1    Scheller, D.2    Rose, S.3
  • 88
    • 72749110467 scopus 로고    scopus 로고
    • Continuous rotigotine administration reduces dyskinesia resulting from pulsatile treatment with rotigotine or l-DOPA in MPTP-treated common marmosets
    • 19833125 10.1016/j.expneurol.2009.10.004 1:CAS:528:DC%2BC3cXotFWl
    • KA Stockwell DK Scheller LA Smith, et al. 2010 Continuous rotigotine administration reduces dyskinesia resulting from pulsatile treatment with rotigotine or l-DOPA in MPTP-treated common marmosets Exp Neurol 221 79 85 19833125 10.1016/j.expneurol.2009.10.004 1:CAS:528:DC%2BC3cXotFWl
    • (2010) Exp Neurol , vol.221 , pp. 79-85
    • Stockwell, K.A.1    Scheller, D.K.2    Smith, L.A.3
  • 89
    • 0022501055 scopus 로고
    • Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734
    • J Van der Weide JB De Vries PG Tepper, et al. 1986 Pharmacological profiles of three new, potent and selective dopamine receptor agonists: N-0434, N-0437 and N-0734 Eur J Pharmacol 125 273 282 3743637 10.1016/0014-2999(86) 90037-3 (Pubitemid 16075440)
    • (1986) European Journal of Pharmacology , vol.125 , Issue.2 , pp. 273-282
    • Van Der Weide, J.1    De Vries, J.B.2    Tepper, P.G.3    Horn, A.S.4
  • 91
    • 0242665791 scopus 로고    scopus 로고
    • Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing
    • DOI 10.1046/j.1471-4159.2003.02109.x
    • BJ Venton H Zhang PA Garris, et al. 2003 Real-time decoding of dopamine concentration changes in the caudate-putamen during tonic and phasic firing J Neurochem 87 1284 1295 14622108 10.1046/j.1471-4159.2003.02109.x 1:CAS:528:DC%2BD3sXps1OhsLc%3D (Pubitemid 37485084)
    • (2003) Journal of Neurochemistry , vol.87 , Issue.5 , pp. 1284-1295
    • Venton, B.J.1    Zhang, H.2    Garris, P.A.3    Phillips, P.E.M.4    Sulzer, D.5    Wightman, R.M.6
  • 92
    • 33846438955 scopus 로고    scopus 로고
    • Randomized, blind, controlled trial of transdermal rotigotine in early Parkinson disease
    • DOI 10.1212/01.wnl.0000252355.79284.22, PII 0000611420070123000009
    • RL Watts J Jankovic C Waters, et al. 2007 Randomized, blind, controlled trial of transdermal rotigotine in early Parkinson disease Neurology 68 272 276 17202432 10.1212/01.wnl.0000252355.79284.22 1:CAS:528:DC%2BD2sXlt12msg%3D%3D (Pubitemid 46148338)
    • (2007) Neurology , vol.68 , Issue.4 , pp. 272-276
    • Watts, R.L.1    Jankovic, J.2    Waters, C.3    Rajput, A.4    Boroojerdi, B.5    Rao, J.6
  • 93
    • 73349107680 scopus 로고    scopus 로고
    • Long-term safety of rotigotine transdermal patch in early-stage Parkinson's disease: Results from 4 years
    • RL Watts R Pahwa KE Lyons, et al. 2009 Long-term safety of rotigotine transdermal patch in early-stage Parkinson's disease: results from 4 years Mov Disord 24 S1 286
    • (2009) Mov Disord , vol.24 , Issue.S1 , pp. 286
    • Watts, R.L.1    Pahwa, R.2    Lyons, K.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.