A new technique for assessing renal transplant perfusion preoperatively using contrast-enhanced ultrasound (CEUS) and three-dimensional ultrasound (3DUS) - A porcine model pilot study

Ultraschall in der Medizin

Volumn 32, Issue SUPPL. 2, 2011, Pages

  Stenberg, B ^a   Talbot, D ^a   Khurram, M ^a   Kanwar, A ^a   Ray, C ^a   Mownah, O ^a   White, K ^b   Elliott, S T ^a  

^a FREEMAN HOSPITAL   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

contrast enhanced ultrasound; kidney transplant; three dimensional ultrasound; volume ultrasound

Indexed keywords

CONTRAST AGENT BR1; CONTRAST MEDIUM; DIAGNOSTIC AGENT; PHOSPHOLIPID; SULFUR HEXAFLUORIDE;

ANIMAL; ARTICLE; BLOOD FLOW; BLOOD FLOW VELOCITY; BLOOD PRESSURE; COMPUTER ASSISTED DIAGNOSIS; ECHOGRAPHY; ELECTRON MICROSCOPY; GLOMERULUS; IMAGE ENHANCEMENT; IN VITRO STUDY; INDUCED HYPOTHERMIA; INFUSION PUMP; ISCHEMIA; KIDNEY; KIDNEY TRANSPLANTATION; METHODOLOGY; PATHOLOGY; PHYSIOLOGY; PILOT STUDY; PREOPERATIVE CARE; REFERENCE VALUE; REPERFUSION INJURY; SENSITIVITY AND SPECIFICITY; SWINE; THREE DIMENSIONAL IMAGING; TISSUE PRESERVATION; VASCULARIZATION;

ANIMALS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CONTRAST MEDIA; HYPOTHERMIA, INDUCED; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; INFUSION PUMPS; ISCHEMIA; KIDNEY; KIDNEY GLOMERULUS; KIDNEY TRANSPLANTATION; MICROSCOPY, ELECTRON; PHOSPHOLIPIDS; PILOT PROJECTS; PREOPERATIVE CARE; REFERENCE VALUES; REGIONAL BLOOD FLOW; REPERFUSION INJURY; SENSITIVITY AND SPECIFICITY; SULFUR HEXAFLUORIDE; SWINE; TISSUE PRESERVATION; ULTRASONOGRAPHY;

EID: 84855176417     PISSN: 01724614     EISSN: 14388782     Source Type: Journal    
DOI: 10.1055/s-0031-1281650     Document Type: Article

References (18)

1. Global Observatory on Donation & Transplantation. http://www.transplant-observatory.org (online) (accessed 11 / 08 / 10)
2. National Kidney Foundation. http://www.kidney.org.uk/campaigns/ Press-Media/nkf-press-oct06.html (online)(accessed 26 / 03 / 10)
3. Moers C, Smits J M., Maathuis M J. Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation. N Engl J Med 2009 360 7-19
4. Talbot D, Shenton B K., Buckley P E. et al. Experiences learned in the successful establishment of a nonheart beating donor program for renal transplantation. J Urology 2003 170 1088-1092 (Pubitemid 37108085)
5. Choi J D. et al. Renal Damage Caused by Warm Ischaemia During Laparoscopic and Robot- Assisted Partial Nephrectomy: An Assessment Using Tc 99m-DTPA Glomerular Filtration Rate. Eur Urol 2010
6. Lefèvre F, Correas J M., Briançon S. Contrast-enhanced sonography of the renal transplant using triggered pulse-inversion imaging: preliminary results. Ultrasound Med Biol 2002 28 303-314 (Pubitemid 34308910)
7. Fischer T, Filimonow S, Rudolph J. Arrival time parametric imaging: a new ultrasound technique for quantifying perfusion of kidney grafts. Ultraschall in Med 2008 29 418-423
8. Kay D H., Mazonakis C, Geddes C et al. Ultrasonic microbubble contrast agents and the transplant kidney. Clin Radiol 2009 64 1081-1087
9. Stenberg B, Elliott S T. Diagnosis of gallbladder problems using three-dimensional ultrasound. Eur Radiol 2010 20 908-914
10. Fischer T, Filimonow S, Dieckhöfer J. Improved diagnosis of early kidney allograft dysfunction by ultrasound with echo enhancer a new method for the diagnosis of renal perfusion. Nephrol Dial Transplant 2006 21 2921-2929 (Pubitemid 44542251)
11. Kay D H., Mazonakis C, Geddes C et al. Ultrasonic microbubble contrast agents and the transplant kidney. Clin Radiol 2009 64 1081-1087
12. Wagner M, Rhodes G, Wang C et al. Ischemic Injury to Kidney Induces Glomerular Podocyte Effacement and Dissociation of Slit Diaphragm Proteins Neph1 and ZO-1. Journal of Biological Chemistry 2008 283 35 579-35 589
13. Cosgrove D, Eckersley R. Contrast enhanced ultrasound: basic physics and technology overview. Chapter in Enhancing the role of ultrasound with contrast agents (edited by Lencioni R.) Italy Springer-Verlag 2006
14. Chen N G., Fowlkes J B., Carson P L. et al. Rapid 3-D imaging of contrast flow: application in a perfused kidney phantom. Ultrasound med biol 2009 35 813-828
15. Quaia E, (edited by). Contrast media in ultrasonography. Berlin Springer-Verlag 2005
16. Bracco Ltd. Contrast enhanced ultrasoundexplore life from the inside: Radiology Monograph. Bracco UK Ltd 2010
17. Jimenez C, Gracia R de, Aguilera A. In Situ Kidney Insonation With Microbubble Contrast Agents Does Not Cause Renal Tissue Damage in a Porcine Model. J Ultrasound Med 2008 27 1607-1615
18. Miller D J., Dou C, Wiggins R C. Contrast-enhanced diagnostic ultrasound causes renal tissue damage in a porcine model. J Ultrasound Med 2010 29 (10) 1391-1401