Mutations of mitochondrial DNA as potential biomarkers in breast cancer

Anticancer Research

Volumn 31, Issue 12, 2011, Pages 4267-4271

  Cai, Feng Feng ^a   Kohler, Corina ^a   Zhang, Bei ^a   Chen, Wei Jie ^a   Barekati, Zeinab ^a   Garritsen, Henk S P ^b   Lenner, Per ^c   Toniolo, Paolo ^d   Zhang, Jing Jie ^e   Zhong, Xiao Yan ^a  

^a UNIVERSITY WOMEN S HOSPITAL   (Switzerland)

^b Institute for Clinical Transfusion Medicine   (Germany)

^c UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

^e An hui Medical University   (China)

Author keywords

Breast cancer; D loop region; Mitochondrial DNA; MtDNA mutation; Plasma

Indexed keywords

BIOLOGICAL MARKER; MITOCHONDRIAL DNA;

ADULT; ARTICLE; BLOOD SAMPLING; BREAST CANCER; CANCER PATIENT; CANCER TISSUE; CLINICAL ARTICLE; GENE MUTATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL;

AGED; BREAST NEOPLASMS; DNA; DNA PRIMERS; DNA, MITOCHONDRIAL; FEMALE; GERM-LINE MUTATION; HUMANS; MIDDLE AGED; MITOCHONDRIA; MUTATION; PROTEIN STRUCTURE, TERTIARY; TUMOR MARKERS, BIOLOGICAL;

EID: 84855169026     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Wallace DC: Mitochondrial DNA sequence variation in human evolution and disease. Proc Natl Acad Sci USA 91: 8739-8746, 1994.
2. Hiss MS, Usadel H, Caballero OL, Wu L, Buta MR, Eleff SM, Jen J and Sidransky D: Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287: 2017-2019, 2000. (Pubitemid 30158678)
3. Anderson S, Bankier AT, Barrell BG, de Bruijn MH, Coulson AR, Drouin J, Eperon IC, Nierlich DP, Roe BA, Sanger F, Schreier PH, Smith AJ, Staden R and Young IG: Sequence and organization of the human mitochondrial genome. Nature 290: 457-465, 1981. (Pubitemid 11159074)
4. Stoneking M: Hypervariable sites in the mtDNA control region are mutational hotspots. Am J Hum Genet 67: 1029-1032, 2000.
5. Lu J, Sharma LK and Bai Y: Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis. Cell Res 19: 802-815, 2009.
6. Takeuchi H, Fujimoto A and Hoon DS: Detection of mitochondrial DNA alterations in plasma of malignant melanoma patients. Ann NY Acad Sci 1022: 50-54, 2004. (Pubitemid 38951581)
7. Hibi K, Nakayama H, Yamazaki T, Takase T, Taguchi M, Kasai Y, Ito K, Akiyama S and Nakao A: Detection of mitochondrial DNA alterations in primary tumors and corresponding serum of colorectal cancer patients. Int J Cancer 94: 429-431, 2001. (Pubitemid 32906076)
8. Radpour R, Kohler C, Haghighi MM, Fan AX, Holzgreve W and Zhong XY: Methylation profiles of 22 candidate genes in breast cancer using high-throughput MALDI-TOF mass array. Oncogene 28: 2969-2978, 2009.
9. Zhong XY, Ladewig A, Schmid S, Wight E, Hahn S and Holzgreve W: Elevated level of cell-free plasma DNA is associated with breast cancer. Arch Gynecol Obstet 276: 327-331, 2007. (Pubitemid 47397546)
10. Ma Y, Bai RK, Trieu R and Wong LJ: Mitochondrial dysfunction in human breast cancer cells and their transmitochondrial cybrids. Biochim Biophys Acta 1797: 29-37, 2010.
11. Parrella P, Xiao Y, Fliss M, Sanchez-Cespedes M, Mazzarelli P, Rinaldi M, Nicol T, Gabrielson E, Cuomo C, Cohen D, Pandit S, Spencer M, Rabitti C, Fazio VM and Sidransky D: Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates. Cancer Res 61: 7623-7626, 2001. (Pubitemid 32995057)
12. Tan DJ, Bai RK and Wong LJ: Comprehensive scanning of somatic mitochondrial DNA mutations in breast cancer. Cancer Res 62: 972-976, 2002.
13. Kumimoto H, Yamane Y, Nishimoto Y, Fukami H, Shinoda M, Hatooka S and Ishizaki K: Frequent somatic mutations of mitochondrial DNA in esophageal squamous cell carcinoma. Int J Cancer 108: 228-231, 2004. (Pubitemid 37541775)
14. Zhu W, Qin W, Bradley P, Wessel A, Puckett CL and Sauter ER: Mitochondrial DNA mutations in breast cancer tissue and in matched nipple aspirate fluid. Carcinogenesis 26: 145-152, 2005. (Pubitemid 40207709)
15. Chen JZ, Gokden N, Greene GF, Green B and Kadlubar FF: Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis. Carcinogenesis 24: 1481-1487, 2003. (Pubitemid 37160838)
16. van Oven M and Kayser M: Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat 30: E386-394, 2009.
17. Lo YM, Lun FM, Chan KC, Tsui NB, Chong KC, Lau TK, Leung TY, Zee BC, Cantor CR and Chiu RW: Digital PCR for the molecular detection of fetal chromosomal aneuploidy. Proc Natl Acad Sci USA 104: 13116-13121, 2007. (Pubitemid 351737602)
18. Diehl F, Schmidt K, Choti MA, Romans K, Goodman S, Li M, Thornton K, Agrawal N, Sokoll L, Szabo SA, Kinzler KW, Vogelstein B and Diaz LA Jr.: Circulating mutant DNA to assess tumor dynamics. Nat Med 14: 985-990, 2008.
19. Chiu RW, Chan KC, Gao Y, Lau VY, Zheng W, Leung TY, Foo CH, Xie B, Tsui NB, Lun FM, Zee BC, Lau TK, Cantor CR and Lo YM: Noninvasive prenatal diagnosis of fetal chromosomal aneuploidy by massively parallel genomic sequencing of DNA in maternal plasma. Proc Natl Acad Sci USA 105: 20458-20463, 2008.
20. Korshunova Y, Maloney RK, Lakey N, Citek RW, Bacher B, Budiman A, Ordway JM, McCombie WR, Leon J, Jeddeloh JA and McPherson JD: Massively parallel bisulphite pyrosequencing reveals the molecular complexity of breast cancer-associated cytosine-methylation patterns obtained from tissue and serum DNA. Genome Res 18: 19-29, 2008.
21. Beck J, Urnovitz HB, Mitchell WM and Schutz E: Next generation sequencing of serum circulating nucleic acids from patients with invasive ductal breast cancer reveals differences to healthy and nonmalignant controls. Mol Cancer Res 8: 335-342, 2010.