CD61 and fibrinogen immunohistochemical study to improve the post-mortem diagnosis in a fat embolism syndrome clinically demonstrated by transesophageal echocardiography

Forensic Science International

Volumn 202, Issue 1-3, 2010, Pages

  Neri, Margherita ^a   Riezzo, Irene ^a   Dambrosio, Michele ^a   Pomara, Cristoforo ^a   Turillazzi, Emanuela ^a   Fineschi, Vittorio ^a  

^a UNIVERSITY OF FOGGIA   (Italy)

Author keywords

CD61; Confocal laser scanning microscopy; Fat embolism syndrome; Fibrinogen; Immunohistochemistry; Transesophageal echocardiography

Indexed keywords

BONE CEMENT; CD61 ANTIGEN; FIBRIN; FIBRINOGEN; LIPID; METAL; METHYLPREDNISOLONE; OIL SCARLET;

ADULT; ARTICLE; AUTOPSY; BRAIN ARTERY; CASE REPORT; CLINICAL FEATURE; CONFOCAL LASER MICROSCOPY; CYANOSIS; DISEASE CLASSIFICATION; DISEASE SEVERITY; DISORIENTATION; END TIDAL CARBON DIOXIDE TENSION; FAT BODY; FAT EMBOLISM; FATALITY; FEMUR NECK FRACTURE; FIBRIN DEPOSITION; FRACTURE IMMOBILIZATION; GLOMERULUS CAPILLARY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOTENSION; HYPOXEMIA; IMMUNOHISTOCHEMISTRY; LUNG PARENCHYMA; MALE; MOTORCYCLE; ORTHOPEDIC PROSTHESIS; ORTHOPEDIC SURGERY; PEROPERATIVE ECHOGRAPHY; PRIORITY JOURNAL; PULMONARY ARTERY; QUANTITATIVE ANALYSIS; RESPIRATORY DISTRESS; RESPIRATORY FAILURE; SEIZURE; SHOCK; TACHYCARDIA; THROMBOCYTE AGGREGATION; TISSUE DISTRIBUTION; TRACTION THERAPY; TRAFFIC ACCIDENT; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; WHEEZING;

EID: 84755161796     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2010.04.034     Document Type: Article

References (32)

1. Goldhaber S.Z. Pulmonary embolism. Lancet 2004, 363:1295-1305.
2. Watanabe S., Terazawa K., Matoba N., Yamada N. An autopsy case of intraoperative death due to pulmonary fat embolism-possibly caused by release of tourniquet after multiple muscle-release and tenotomy of the bilateral lower limbs. Forensic Sci. Int. 2007, 171:73-77.
3. Waller D.A., Bennett M.K., Corris P.A., Dark J.H. Donor-acquires fat embolism causing primary organ failure after lung transplantation. Ann. Thorac. Surg. 1995, 59:1565-1566.
4. Dang N.C., Johnson C., Eslami-Farsani M., Haywood L.J. Bone marrow embolism in sickle cell disease: a review. Am. J. Hematol. 2005, 79:61-67.
5. Tsokos M., Paulsen F., Petri S., Madea B., Puschel K., Turk E.E. Histologic, immunohistochemical and ultrastructural findings in human blast lung injury. Am. J. Respir. Crit. Care Med. 2003, 168:549-555.
6. Pape H.C., Giannoudis P.V. Editorial. Injury 2006, 37:S1-S2.
7. Talbot M., Schemitsch E.H. Fat embolism syndrome: history, definition, epidemiology. Injury 2006, 37:S3-S7.
8. Taviloglu K., Yanar H. Fat embolism syndrome. Surg. Today 2007, 37:5-8.
9. Kontakis G.M., Tossounidis T., Weiss K., Pape H.C., Giannoudis P.V. Fat embolism: special situations bilateral femoral fractures and pathologic femoral fractures. Injury 2006, 37:S19-S24.
10. Neri M., Turillazzi E., Riezzo I., Fineschi V. The determination of firing distance applying a microscopic quantitative method and confocal laser scanning microscopy for detection of gunshot residue particles. Int. J. Legal Med. 2007, 121:287-292.
11. Robb-Smith A.H. Pulmonary fat-embolism. Lancet 1941, 1:135-141.
12. Schmid A., Tzur L., Leshko A., Krieger B.P. Silicone embolism syndrome: a case report, review of the literature, and comparison with fat embolism syndrome. Chest 2005, 127:2276-2281.
13. Ellingsen Husebye E., Lyberg T., Røise O. Bone marrow fat in the circulation: clinical entities and pathophysiological mechanisms. Injury 2006, 37:S8-S18.
14. Sevitt S. The significance and pathology of fat embolism. Ann. Clin. Res. 1977, 9:173-180.
15. Turillazzi E., Riezzo I., Neri M., Pomara C., Cecchi R., Fineschi V. The diagnosis of fatal pulmonary fat embolism using quantitative morphometry and confocal laser scanning microscopy. Pathol. Res. Pract. 2008, 204:259-266.
16. Ramírez G., Romero A., García-Vallejo J.J., Muñoz M. Detection and removal of fat particles from postoperative salvaged blood in orthopedic surgery. Transfusion 2002, 42:66-75.
17. Arai F., Kita T., Nakai T., Hori T., Maki N., Kakiuchi M., Sasaki S. Histopathologic features of fat embolism in fulminant fat embolism syndrome. Anesthesiology 2007, 107:509-511.
18. Christie J., Robinson C.M., Pell A.C., McBirnie J., Burnett R. Transcardiac echocardiography during invasive intramedullary procedures. J. Bone Joint Surg. Br. 1995, 77:450-455.
19. ten Duis H.J. The fat embolism syndrome. Injury 1997, 28:77-85.
20. Mellor A., Soni N. Fat embolism. Anaesthesia 2001, 56:145-154.
21. Bulger E.M., Smith D.G., Maier R.V., Jurkovich G.J. Fat embolism syndrome. A 10-year review. Arch. Surg. 1997, 132:435-439.
22. Fabian T.C., Hoots A.V., Stanford D.S., Patterson C.R., Mangiante E.C. Fat embolism syndrome: prospective evaluation in 92 fracture patients. Crit. Care Med. 1990, 18:42-46.
23. Habashi N.M., Andrews P.L., Scalea T.M. Therapeutic aspects of fat embolism syndrome. Injury 2006, 37:S68-S73.
24. Dennis F. System of surgery 1895, Lea Brothers, Philadelphia.
25. Emson H.E. Fat embolism studied in 100 patients dying after injury. J. Clin. Pathol. 1958, 11:28-35.
26. Falzi G., Henn R., Spann W. On pulmonary fat embolism after injuries with different periods of survival. Munch. Med. Wochenschr. 1964, 106:978-981.
27. Holczabek W. Tin layer chromatographic studies on lipid extracts from the human lung with special reference to fat embolism. Dtsch. Z. Gesamte Gerichtl. Med. 1964, 55:242-246.
28. Holczabek W., Machata G. Gaschromatographischc Untersuchungen zur Frage der Entschüng der Fettembolie beim Menschen. Beitr. Gerichtl. Med. 1971, 28:82-87.
29. Brinkmann B., Borgner M., von Bulow M. Fat embolism of the lungs as the cause of death. Etiology, pathogenesis and reasoning. Z. Rechtsmed. 1976, 78:255-272.
30. Bunai Y., Yoshimi N., Komoriya H., Iwasa M., Ohya I. An application of a quantitative analytical system for the grading of pulmonary fat embolisms. Forensic Sci. Int. 1988, 39:263-269.
31. Busuttil A., Hanley J.J. A semi-automated micro-method for the histological assessment of fat embolism. Int. J. Legal Med. 1994, 107:90-95.
32. Preuß J., Dettmeyer R., Ortmann C., Lignitza E., Madea B. Pulmonary fat embolism in cases of fatal hypothermia. Forensic Sci. Int. 2007, 169:S5.