Influence of blood viscosity to cerebral blood flow in older humans compared to young subjects

Clinical Neurophysiology

Volumn 123, Issue 1, 2012, Pages 117-120

  Santos Galduróz, Ruth F ^a,b   Bueno, Orlando F A ^c   Yamaga, Lilian I ^d   Armani, Fernanda ^c   Galduróz, José Carlos F ^c  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b UNIVERSIDADE FEDERAL DO ABC   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^d Hospital Israelita and Research Institute Albert Einstein   (Brazil)

Author keywords

Ageing; Blood viscosity; Cerebral blood flow

Indexed keywords

ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; BLOOD SAMPLING; BLOOD VISCOSITY; BRAIN BLOOD FLOW; BRAIN REGION; HUMAN; HUMAN EXPERIMENT; LEFT HEMISPHERE; MALE; NORMAL HUMAN; PARIETAL LOBE; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TEMPORAL LOBE; VISCOMETRY;

ADULT; AGED; BLOOD VISCOSITY; CEREBROVASCULAR CIRCULATION; CEREBRUM; HUMANS; MALE; MIDDLE AGED; REGIONAL BLOOD FLOW; TECHNETIUM TC 99M EXAMETAZIME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; YOUNG ADULT;

EID: 84655169685     PISSN: 13882457     EISSN: 18728952     Source Type: Journal    
DOI: 10.1016/j.clinph.2011.05.025     Document Type: Article

References (21)

1. Asllani I., Habeck C., Borogovac A., Brown T.R., Brickman A.M., Stern Y. Separating function from structure in perfusion imaging of the aging brain. Hum Brain Mapp. 2009, 30:2927-2935.
2. Baskurt O.K., Meiselman H.J. Blood rheology and hemodynamics. Semin Thromb Hemost 2003, 29:435-450.
3. Bessis M., Weed R.I. The structure of normal and pathologic erythrocytes. Adv Biol Med Phys 1973, 14:35-91.
4. 99mTc-HMPAO SPET study. Eur J Nucl Med 1996, 23:1329-1337.
5. Galduróz J.C.F., Antunes H.K., Santos R.F. Gender- and age-related variations in blood viscosity in normal volunteers: A study of the effects of extract of Allium sativum and Ginkgo biloba. Phytomedicine 2007, 14:447-451.
6. Garraux G., Salmon E., Degueldre C., Lemaire C., Laureys S., Franck G. Comparison of impaired subcortico-frontal metabolic networks in normal aging, subcortico-frontal dementia, and cortical frontal dementia. Neuroimage 1999, 10:149-162.
7. Herholz K., Salmon E., Perani D., Baron J.C., Holthoff V., Frolich L., et al. Discrimination between Alzheimer dementia and controls by automated analysis of multicenter FDG PET. Neuroimage 2002, 17:302-316.
8. Hou W.C., Tsay H.S., Liang H.J., Lee T.Y., Wang G.J., Liu D.Z. Improving abnormal hemorheological parameters in aging guinea pigs by water-soluble extracts of Salvia miltiorrhiza Bunge. J Ethnopharmacol 2007, 111:483-489.
9. Jensen T., Retterstøl L.J., Sandset P.M., Godal H.C., Skjønsberg O.H. A daily glass of red wine induces a prolonged reduction in plasma viscosity: a randomized controlled trial. Blood Coagul Fibrinolysis 2006, 17:471-476.
10. Kalvach P., Gregova D. Cerebral microangiopathy in the mosaic of new discoveries. J Neurol Sci 2005, 229-230:7-12.
11. Klinge P., Ruckert N., Schuhmann M., Berding G., Brinker T., Knapp W., et al. Neuropsychological sequels to changes in global cerebral blood flow and cerebrovascular reserve capacity after shunt treatment in chronic hydrocephalus-a quantitative PET-study. Acta Neurochir Suppl 2002, 81:55-57.
12. Lessin L.S., Klug P.P., Jensen W.N. Clinical implications of red cell shape. Adv Intern Med 1976, 21:451-500.
13. Lowe G.D.O., Drummond M.M., Forbes C.D., Barbenel J.C. The effects of age and cigarette-smoking on blood and plasma viscosity in men. Scott Med J 1980, 25:13-17.
14. Marcinkowska-Gapińska A., Kowal P. Comparative analysis of chosen hemorheological methods in a group of stroke patients. Clin Hemorheol Microcirc 2009, 41(1):27-33.
15. Matsuda H., Ohnishi T., Asada T., Li Z.J., Kanetaka H., Imabayashi E., et al. Correction for partial-volume effects on brain perfusion SPECT in healthy men. J Nucl Med 2003, 44:1243-1252.
16. O'Brien J.T. Introduction: for debate: should neuroimaging be a routine investigation in all cases of suspected dementia?. Int Psychogeriatr 2007, 19:525-526.
17. Olson E.E., McKeon R.J. Characterization of cellular and neurological damage following unilateral hypoxia/ischemia. J Neurol Sci 2004, 227:7-19.
18. 99mTc-HMPAO SPET in healthy subjects at rest: normal distribution and effect of age and gender. Eur J Nucl Med Mol Imaging 2002, 29:67-75.
19. Rand P.W., Lacombe E., Hunt H.E., Austin W.H. Viscosity of normal human blood under normothermic and hypothermic conditions. J Applied Physiol 1964, 19:117-121.
20. Santos R.F., Galduróz J.C., Barbieri A., Castiglioni M.L., Ytaya L.Y., Bueno O.F. Cognitive performance, SPECT, and blood viscosity in elderly non-demented people using Ginkgo biloba. Pharmacopsychology 2003, 36:127-133.
21. Ushijima Y., Okuyama C., Mori S., Nakamura T., Kubota T., Nishimura T. Relationship between cognitive function and regional cerebral blood flow in Alzheimer's disease. Nucl Med Commun 2002, 23:779-784.