Overview of currently approved veterinary vaccine potency testing methods and methods in development that do not require animal use

Procedia in Vaccinology

Volumn 5, Issue , 2011, Pages 171-174

  Draayer, Hans ^a  

^a ZOETIS   (United States)

Author keywords

ELISA; In vitro; Potency; Titration

Indexed keywords

ANTIGEN; INACTIVATED VACCINE; LEPTOSPIROSIS VACCINE; MONOCLONAL ANTIBODY; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; VACCINE; VETERINARY VACCINE;

ACCURACY; ANIMAL HEALTH; ARTICLE; ASSAY; DRUG POTENCY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMAGGLUTINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNODIFFUSION; IN VITRO STUDY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; POTENCY ASSAY; PRIORITY JOURNAL; SEROLOGY; VACCINATION;

EID: 84555190324     PISSN: None     EISSN: 1877282X     Source Type: Journal    
DOI: 10.1016/j.provac.2011.10.016     Document Type: Article

References (6)

1. United States Code of Federal Regulations. Title 9 - Animals and Animal Products, Chapter 1 - Animal and Plant Health Inspection Service, Department of Agriculture, Subchapter E - Viruses, Serums, Toxins, and Analogous Products; Organisms and Vectors - Part 113.304. Feline Panleukopenia Vaccine. Available at: http://www.aphis.usda.gov/animal_health/vet_biologics/vb_cfr.shtml.
2. U.S. Department of Agriculture, Animal and Plant Health Inspection Service (APHIS). Supplemental Assay Methods Nos. 624-627. Washington, DC: APHIS, last updated December 2010. Available from: http://www.aphis.usda.gov/animal_health/vet_biologics/vb_sams_600_series.shtml.
3. Reed L.J., Muench H. A simple method of estimating fifty per cent endpoints. Am J Hyg 1938, 27:493-497.
4. Finney DJ. Statistical Method in Biological Assay. New York: Hafner Publishing, 1952:512-53.
5. Estimated from Product Classifications published in the USDA Veterinary Biological Products Listing, excluding poultry and aquaculture products http://www.aphis.usda.gov/animal_health/vet_biologics/publications/CurrentProdCodeBook.pdf.
6. Knight, P.A, C Burnett, A M Whitaker, J Queminet. The titration of clostridial toxoids and antisera in cell culture. Developments in biological standardization. 02/1986;64:129-36.