Selection of an antiviral RNA aptamer against hemagglutinin of the subtype H5 avian influenza virus

Nucleic Acid Therapeutics

Volumn 21, Issue 6, 2011, Pages 395-402

  Park, Sun Young ^a   Kim, Seho ^a   Yoon, Hana ^a   Kim, Kyung Bo ^a   Kalme, Sheetal S ^a,b   Oh, Sangtaek ^c   Song, Chang Seon ^a   Kim, Dong Eun ^a  

^a Konkuk University   (South Korea)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^c Kookmin University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; APTAMER; HAS15 5; HEMAGGLUTININ; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ANTIVIRAL THERAPY; ARTICLE; DRUG EFFICACY; DRUG PROTEIN BINDING; INFLUENZA VIRUS A; INFLUENZA VIRUS A H5; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

ANIMALS; ANTIVIRAL AGENTS; APTAMERS, NUCLEOTIDE; BINDING SITES; CHICK EMBRYO; HEMAGGLUTINATION INHIBITION TESTS; HEMAGGLUTININS; HEMAGGLUTININS, VIRAL; INFLUENZA A VIRUS, H5N1 SUBTYPE; NUCLEIC ACID CONFORMATION; ORTHOMYXOVIRIDAE INFECTIONS; RECOMBINANT PROTEINS; SELEX APTAMER TECHNIQUE; SENSITIVITY AND SPECIFICITY;

AVES; AVIAN INFLUENZA VIRUS; INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE; RNA VIRUSES;

EID: 84555188066     PISSN: 21593337     EISSN: None     Source Type: Journal    
DOI: 10.1089/nat.2011.0321     Document Type: Article

References (31)

1. BEIGEL, J.H., FARRAR, J., HAN, A.M., HAYDEN, F.G., HYER, R., DE JONG, M.D., LOCHINDARAT, S., NGUYEN, T.K., NGUYEN, T.H., TRAN, T.H, NICOLIL A, TOUCH S., YUEN K.Y.; WRITING COMMITE OF THE WORLD HEALTH ORGANIZATION (WHO) CONSULTATION ON HUMAN INFLUENZA A/H5. (2005). Avian influenza A (H5N1) infection in humans. N. Engl. J. Med. 353, 1374-1385. (Pubitemid 41362705)
2. BIROCCIO, A., HAMM, J., INCITTI, I., DE FRANCESCO, R., and TOMEI, L. (2002). Selection of RNA aptamers that are specific and high-affinity ligands of the hepatitis C virus RNA-dependent RNA polymerase. J. Virol. 76, 3688-3696. (Pubitemid 34250533)
3. CHENG, C., DONG, J., YAO, L., CHEN, A., JIA, R., HUAN, L., GUO, J., SHU, Y., and ZHANG, Z. (2008). Potent inhibition of human influenza H5N1 virus by oligonucleotides derived by SELEX. Biochem. Biophys. Res. Commun. 366, 670-674.
4. DAS, A., SPACKMAN, E., THOMAS, C., SWAYNE, D.E., and SUAREZ, D.L. (2008). Detection of H5N1 high-pathogenicity avian influenza virus in meat and tracheal samples from experimentally infected chickens. Avian Dis. 52, 40-48. (Pubitemid 351497479)
5. DE CLERCQ, E. (2006). Antiviral agents active against influenza A viruses. Nat. Rev. Drug Discov. 5, 1015-1025. (Pubitemid 44835128)
6. ECKERT, D.M., and KIM, P.S. (2001). Mechanisms of viral membrane fusion and its inhibition. Annu. Rev. Biochem. 70, 777-810. (Pubitemid 32662225)
7. ELLINGTON, A.D., and SZOSTAK, J.W. (1990). In vitro selection of RNA molecules that bind specific ligands. Nature 346, 818-822.
8. FOUCHIER, R.A., MUNSTER, V., WALLENSTEN, A., BESTEB-ROER, T.M., HERFST, S., SMITH, D., RIMMELZWAAN, G.F., OLSEN, B., and OSTERHAUS, A.D. (2005). Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls. J. Virol. 79, 2814-2822. (Pubitemid 40270559)
9. FUKUDA, K., VISHNUVARDHAN, D., SEKIYA, S., HWANG, J., KAKIUCHI, N., TAIRA, K., SHIMOTOHNO, K., KUMAR, P.K., and NISHIKAWA, S. (2000). Isolation and characterization of RNA aptamers specific for the hepatitis C virus non-structural protein 3 protease. Eur. J. Biochem. 267, 3685-3694. (Pubitemid 30423030)
10. HWANG, B., CHO, J.S., YEO, H.J., KIM, J.H., CHUNG, K.M., HAN, K., JANG, S.K., and LEE, S.W. (2004). Isolation of specific and high-affinity RNA aptamers against NS3 helicase domain of hepatitis C virus. RNA 10, 1277-1290. (Pubitemid 38989013)
11. JANG, K.J., LEE, N.R., YEO, W.S., JEONG, Y.J., and KIM, D.E. (2008). Isolation of inhibitory RNA aptamers against severe acute respiratory syndrome (SARS) coronavirus NTPase/Helicase. Biochem. Biophys. Res. Commun. 366, 738-744.
12. JEON, S.H., and ARNON, R. (2002). Immunization with influenza virus hemagglutinin globular region containing the receptor-binding pocket. Viral Immunol. 15, 165-176. (Pubitemid 34273446)
13. JEON, S.H., KAYHAN, B., BEN-YEDIDIA, T., and ARNON, R. (2004). A DNA aptamer prevents influenza infection by blocking the receptor binding region of the viral hemaggluti-nin. J. Biol. Chem. 279, 48410-48419. (Pubitemid 39540998)
14. KAWAOKA, Y., YAMNIKOVA, S., CHAMBERS, T.M., LVOV, D.K., and WEBSTER, R.G. (1990). Molecular characterization of a new hemagglutinin, subtype H14, of influenza A virus. Virology 179, 759-767.
15. KILLIAN, M.L. (2008). Hemagglutination assay for the avian influenza virus. Methods Mol. Biol. 436, 47-52.
16. KLENK, H.D., ROTT, R., ORLICH, M., and BLODORN, J. (1975). Activation of influenza A viruses by trypsin treatment. Virology 68, 426-439.
17. LIU S., LI R., ZHANG R., CHAN C.C.S., XI B., ZHU Z., YANG J., POON V.K.M., ZHOU J., CHEN M., MüNCH J., KIRCHHOFF F., PLESCHKA S., HAARMANN T., DIETRICH U., PAN C., DU L., JIANG S., and ZHENG B. (2011). CL-385319 inhibits H5N1 avian influenza A virus infection by blocking viral entry. Eur. J. Pharmacol. 660, 460-467.
18. LUO, G., TORRI, A., HARTE, W.E., DANETZ, S., CIANCI, C., TILEY, L., DAY, S., MULLANEY, D., YU, K.L., OUELLET, C., DEXTRAZE, P., MEANWELL, N., COLONNO, R., and KRYSTAL, M. (1997). Molecular mechanism underlying the action of a novel fusion inhibitor of influenza A virus. J. Virol. 71, 4062-4070. (Pubitemid 27172422)
19. NIMJEE, S.M., RUSCONI, C.P., and SULLENGER, B.A. (2005). Aptamers: An emerging class of therapeutics. Annu. Rev. Med. 56, 555-583. (Pubitemid 40299797)
20. PERKINS, A.C., and MISSAILIDIS, S. (2007). Radiolabelled ap-tamers for tumour imaging and therapy. Q. J. Nucl. Med. Mol. Imaging 51, 292-296. (Pubitemid 350267699)
21. PLOTCH, S.J., O'HARA, B., MORIN, J., PALANT, O., LAR-OCQUE, J., BLOOM, J.D., LANG JR., S.A., DIGRANDI, M.J., BRADLEY, M., NILAKANTAN, R., and GLUZMAN, Y. (1999). Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin. J. Virol. 73, 140-151. (Pubitemid 28565355)
22. RIMMELZWAAN, G.F., BAARS, M., CLAAS, E.C., and OS-TERHAUS, A.D. (1998). Comparison of RNA hybridization, hemagglutination assay, titration of infectious virus and im-munofluorescence as methods for monitoring influenza virus replication in vitro. J. Virol. Methods 74, 57-66. (Pubitemid 28386804)
23. SKEHEL, J.J., and WILEY, D.C. (2000). Receptor binding and membrane fusion in virus entry: The influenza hemagglutinin. Annu. Rev. Biochem. 69, 531-569.
24. STEINHAUER, D.A. (1999). Role of hemagglutinin cleavage for the pathogenicity of influenza virus. Virology 258, 1-20. (Pubitemid 29391776)
25. TOMBELLI, S., and MASCINI, M. (2009). Aptamers as molecular tools for bioanalytical methods. Curr. Opin. Mol. Ther. 11, 179-188.
26. TUERK, C., and GOLD, L. (1990). Systematic evolution of li-gands by exponential enrichment: RNA ligands to bacterio-phage T4 DNA polymerase. Science 249, 505-510.
27. TUERK, C., MACDOUGAL, S., and GOLD, L. (1992). RNA pseudoknots that inhibit human immunodeficiency virus type 1 reverse transcriptase. Proc. Natl. Acad. Sci. USA 89, 6988-6992.
28. UMEHARA, T., FUKUDA, K., NISHIKAWA, F., KOHARA, M., HASEGAWA, T., and NISHIKAWA, S. (2005). Rational design of dual-functional aptamers that inhibit the protease and he-licase activities of HCV NS3. J. Biochem. 137, 339-347. (Pubitemid 40628440)
29. YAMAMOTO, R., KATAHIRA, M., NISHIKAWA, S., BABA, T., TAIRA, K., and KUMAR, P.K. (2000). A novel RNA motif that binds efficiently and specifically to the Ttat protein of HIV and inhibits the trans-activation by Tat of transcription in vitro and in vivo. Genes Cells 5, 371-388. (Pubitemid 30409093)
30. YOSHIMOTO, J., KAKUI, M., IWASAKI, H., SUGIMOTO, H., FUJIWARA, T., and HATTORI, N., (2000). Identification of amino acids of influenza virus HA responsible for resistance to a fusion inhibitor. Stachyflin. Microbiol. Immunol. 44, 677-685.
31. ZUKER, M. (1989). Computer prediction of RNA structure. Methods Enzymol. 180, 262-288. (Pubitemid 20039580)