-
1
-
-
0023614188
-
Dystrophin: the protein product of the Duchenne muscular dystrophy locus
-
Hoffman EP, Brown RH Jr, Kunkel LM, (1987) Dystrophin: the protein product of the Duchenne muscular dystrophy locus. Cell 51: 919-928.
-
(1987)
Cell
, vol.51
, pp. 919-928
-
-
Hoffman, E.P.1
Brown Jr., R.H.2
Kunkel, L.M.3
-
2
-
-
0023614271
-
Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals
-
Koenig M, Hoffman EP, Bertelson CJ, Monaco AP, Feener C, et al. (1987) Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals. Cell 50: 509-517.
-
(1987)
Cell
, vol.50
, pp. 509-517
-
-
Koenig, M.1
Hoffman, E.P.2
Bertelson, C.J.3
Monaco, A.P.4
Feener, C.5
-
3
-
-
0024538824
-
An autosomal transcript in skeletal muscle with homology to dystrophin
-
Love DR, Hill DF, Dickson G, Spurr NK, Byth BC, et al. (1989) An autosomal transcript in skeletal muscle with homology to dystrophin. Nature 339: 55-58.
-
(1989)
Nature
, vol.339
, pp. 55-58
-
-
Love, D.R.1
Hill, D.F.2
Dickson, G.3
Spurr, N.K.4
Byth, B.C.5
-
6
-
-
0025932274
-
Immunolocalization and developmental expression of dystrophin related protein in skeletal muscle
-
Khurana TS, Watkins SC, Chafey P, Chelly J, Tome FM, et al. (1991) Immunolocalization and developmental expression of dystrophin related protein in skeletal muscle. Neuromuscular Disorders 1: 185-194.
-
(1991)
Neuromuscular Disorders
, vol.1
, pp. 185-194
-
-
Khurana, T.S.1
Watkins, S.C.2
Chafey, P.3
Chelly, J.4
Tome, F.M.5
-
7
-
-
0029906168
-
Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene
-
Tinsley JM, Potter AC, Phelps SR, Fisher R, Trickett JI, et al. (1996) Amelioration of the dystrophic phenotype of mdx mice using a truncated utrophin transgene. Nature 384: 349-353.
-
(1996)
Nature
, vol.384
, pp. 349-353
-
-
Tinsley, J.M.1
Potter, A.C.2
Phelps, S.R.3
Fisher, R.4
Trickett, J.I.5
-
8
-
-
10744233235
-
Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer
-
Cerletti M, Negri T, Cozzi F, Colpo R, Andreetta F, et al. (2003) Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer. Gene Ther 10: 750-757.
-
(2003)
Gene Ther
, vol.10
, pp. 750-757
-
-
Cerletti, M.1
Negri, T.2
Cozzi, F.3
Colpo, R.4
Andreetta, F.5
-
9
-
-
4644240389
-
Heregulin ameliorates the dystrophic phenotype in mdx mice
-
Krag TO, Bogdanovich S, Jensen CJ, Fischer MD, Hansen-Schwartz J, et al. (2004) Heregulin ameliorates the dystrophic phenotype in mdx mice. Proceedings of the National Academy of Sciences of the United States of America 101: 13856-13860.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 13856-13860
-
-
Krag, T.O.1
Bogdanovich, S.2
Jensen, C.J.3
Fischer, M.D.4
Hansen-Schwartz, J.5
-
10
-
-
66349121942
-
Functional substitution by TAT-utrophin in dystrophin-deficient mice
-
Sonnemann KJ, Heun-Johnson H, Turner AJ, Baltgalvis KA, Lowe DA, et al. (2009) Functional substitution by TAT-utrophin in dystrophin-deficient mice. PLoS Med 6: e1000083.
-
(2009)
PLoS Med
, vol.6
-
-
Sonnemann, K.J.1
Heun-Johnson, H.2
Turner, A.J.3
Baltgalvis, K.A.4
Lowe, D.A.5
-
11
-
-
79955867741
-
Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse
-
Tinsley JM, Fairclough RJ, Storer R, Wilkes FJ, Potter AC, et al. (2011) Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse. PLoS One 6: e19189.
-
(2011)
PLoS One
, vol.6
-
-
Tinsley, J.M.1
Fairclough, R.J.2
Storer, R.3
Wilkes, F.J.4
Potter, A.C.5
-
12
-
-
77950540612
-
The artificial gene Jazz, a transcriptional regulator of utrophin, corrects the dystrophic pathology in mdx mice
-
Di Certo MG, Corbi N, Strimpakos G, Onori A, Luvisetto S, et al. (2010) The artificial gene Jazz, a transcriptional regulator of utrophin, corrects the dystrophic pathology in mdx mice. Hum Mol Genet 19: 752-760.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 752-760
-
-
Di Certo, M.G.1
Corbi, N.2
Strimpakos, G.3
Onori, A.4
Luvisetto, S.5
-
13
-
-
70449388874
-
Pharmacological activation of PPARbeta/delta stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice
-
Miura P, Chakkalakal JV, Boudreault L, Belanger G, Hebert RL, et al. (2009) Pharmacological activation of PPARbeta/delta stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice. Hum Mol Genet 18: 4640-4649.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4640-4649
-
-
Miura, P.1
Chakkalakal, J.V.2
Boudreault, L.3
Belanger, G.4
Hebert, R.L.5
-
14
-
-
0029967801
-
Molecular and functional analysis of the utrophin promoter
-
Dennis CL, Tinsley JM, Deconinck AE, Davies KE, (1996) Molecular and functional analysis of the utrophin promoter. Nucleic Acids Research 24: 1646-1652.
-
(1996)
Nucleic Acids Research
, vol.24
, pp. 1646-1652
-
-
Dennis, C.L.1
Tinsley, J.M.2
Deconinck, A.E.3
Davies, K.E.4
-
15
-
-
0033598694
-
A second promoter provides an alternative target for therapeutic up-regulation of utrophin in Duchenne muscular dystrophy
-
Burton EA, Tinsley JM, Holzfeind PJ, Rodrigues NR, Davies KE, (1999) A second promoter provides an alternative target for therapeutic up-regulation of utrophin in Duchenne muscular dystrophy. Proceedings of the National Academy of Sciences of the United States of America 96: 14025-14030.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 14025-14030
-
-
Burton, E.A.1
Tinsley, J.M.2
Holzfeind, P.J.3
Rodrigues, N.R.4
Davies, K.E.5
-
16
-
-
0032978374
-
Activation of utrophin promoter by heregulin via the ets-related transcription factor complex GA-binding protein alpha/beta
-
Khurana TS, Rosmarin AG, Shang J, Krag TO, Das S, et al. (1999) Activation of utrophin promoter by heregulin via the ets-related transcription factor complex GA-binding protein alpha/beta. Molecular Biology of the Cell 10: 2075-2086.
-
(1999)
Molecular Biology of the Cell
, vol.10
, pp. 2075-2086
-
-
Khurana, T.S.1
Rosmarin, A.G.2
Shang, J.3
Krag, T.O.4
Das, S.5
-
17
-
-
0033057369
-
Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein
-
Gramolini AO, Angus LM, Schaeffer L, Burton EA, Tinsley JM, et al. (1999) Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein. Proceedings of the National Academy of Sciences of the United States of America 96: 3223-3227.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 3223-3227
-
-
Gramolini, A.O.1
Angus, L.M.2
Schaeffer, L.3
Burton, E.A.4
Tinsley, J.M.5
-
18
-
-
0035830950
-
Sp1 and Sp3 physically interact and co-operate with GABP for the activation of the utrophin promoter
-
Galvagni F, Capo S, Oliviero S, (2001) Sp1 and Sp3 physically interact and co-operate with GABP for the activation of the utrophin promoter. J Mol Biol 306: 985-996.
-
(2001)
J Mol Biol
, vol.306
, pp. 985-996
-
-
Galvagni, F.1
Capo, S.2
Oliviero, S.3
-
19
-
-
0035584042
-
The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy
-
Perkins KJ, Burton EA, Davies KE, (2001) The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystrophy. Nucleic Acids Research 29: 4843-4850.
-
(2001)
Nucleic Acids Research
, vol.29
, pp. 4843-4850
-
-
Perkins, K.J.1
Burton, E.A.2
Davies, K.E.3
-
20
-
-
4644240389
-
Heregulin ameliorates the dystrophic phenotype in mdx mice
-
Krag TO, Bogdanovich S, Jensen CJ, Fischer MD, Hansen-Schwartz J, et al. (2004) Heregulin ameliorates the dystrophic phenotype in mdx mice. Proc Natl Acad Sci U S A 101: 13856-13860.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13856-13860
-
-
Krag, T.O.1
Bogdanovich, S.2
Jensen, C.J.3
Fischer, M.D.4
Hansen-Schwartz, J.5
-
21
-
-
2542441538
-
Okadaic acid augments utrophin in myogenic cells
-
Rodova M, Brownback K, Werle MJ, (2004) Okadaic acid augments utrophin in myogenic cells. Neurosci Lett 363: 163-167.
-
(2004)
Neurosci Lett
, vol.363
, pp. 163-167
-
-
Rodova, M.1
Brownback, K.2
Werle, M.J.3
-
22
-
-
79955856839
-
Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy
-
Chancellor DR, Davies KE, De Moor O, Dorgan CR, Johnson PD, et al. (2011) Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy. J Med Chem 54: 3241-3250.
-
(2011)
J Med Chem
, vol.54
, pp. 3241-3250
-
-
Chancellor, D.R.1
Davies, K.E.2
De Moor, O.3
Dorgan, C.R.4
Johnson, P.D.5
-
23
-
-
80054779433
-
Drug Discovery for Duchenne Muscular Dystrophy via Utrophin Promoter Activation Screening
-
Moorwood C, Lozynska O, Suri N, Napper AD, Diamond SL, et al. (2011) Drug Discovery for Duchenne Muscular Dystrophy via Utrophin Promoter Activation Screening. PLoS One 6: e26169.
-
(2011)
PLoS One
, vol.6
-
-
Moorwood, C.1
Lozynska, O.2
Suri, N.3
Napper, A.D.4
Diamond, S.L.5
-
24
-
-
27444441122
-
The GTPase RhoA increases utrophin expression and stability, as well as its localization at the plasma membrane
-
Bonet-Kerrache A, Fortier M, Comunale F, Gauthier-Rouviere C, (2005) The GTPase RhoA increases utrophin expression and stability, as well as its localization at the plasma membrane. Biochem J 391: 261-268.
-
(2005)
Biochem J
, vol.391
, pp. 261-268
-
-
Bonet-Kerrache, A.1
Fortier, M.2
Comunale, F.3
Gauthier-Rouviere, C.4
-
25
-
-
34547782173
-
Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle
-
Perkins KJ, Basu U, Budak MT, Ketterer C, Baby SM, et al. (2007) Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle. Mol Biol Cell 18: 2864-2872.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 2864-2872
-
-
Perkins, K.J.1
Basu, U.2
Budak, M.T.3
Ketterer, C.4
Baby, S.M.5
-
26
-
-
25444470062
-
The utrophin A 5′-untranslated region confers internal ribosome entry site-mediated translational control during regeneration of skeletal muscle fibers
-
Miura P, Thompson J, Chakkalakal JV, Holcik M, Jasmin BJ, (2005) The utrophin A 5′-untranslated region confers internal ribosome entry site-mediated translational control during regeneration of skeletal muscle fibers. J Biol Chem 280: 32997-33005.
-
(2005)
J Biol Chem
, vol.280
, pp. 32997-33005
-
-
Miura, P.1
Thompson, J.2
Chakkalakal, J.V.3
Holcik, M.4
Jasmin, B.J.5
-
27
-
-
48649086140
-
IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells
-
Miura P, Andrews M, Holcik M, Jasmin BJ, (2008) IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells. PLoS ONE 3: e2309.
-
(2008)
PLoS ONE
, vol.3
-
-
Miura, P.1
Andrews, M.2
Holcik, M.3
Jasmin, B.J.4
-
28
-
-
33749557894
-
MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206
-
Rosenberg MI, Georges SA, Asawachaicharn A, Analau E, Tapscott SJ, (2006) MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206. J Cell Biol 175: 77-85.
-
(2006)
J Cell Biol
, vol.175
, pp. 77-85
-
-
Rosenberg, M.I.1
Georges, S.A.2
Asawachaicharn, A.3
Analau, E.4
Tapscott, S.J.5
-
29
-
-
0842321501
-
MicroRNA targets in Drosophila
-
Enright AJ, John B, Gaul U, Tuschl T, Sander C, et al. (2003) MicroRNA targets in Drosophila. Genome Biol 5: R1.
-
(2003)
Genome Biol
, vol.5
-
-
Enright, A.J.1
John, B.2
Gaul, U.3
Tuschl, T.4
Sander, C.5
-
30
-
-
37549034298
-
-
Local Dystrophin Restoration with Antisense Oligonucleotide PRO051
-
van Deutekom JC, Janson AA, Ginjaar IB, Frankhuizen WS, Aartsma-Rus A, et al. (2007) pp. 2677-2686 Local Dystrophin Restoration with Antisense Oligonucleotide PRO051.
-
(2007)
, pp. 2677-2686
-
-
van Deutekom, J.C.1
Janson, A.A.2
Ginjaar, I.B.3
Frankhuizen, W.S.4
Aartsma-Rus, A.5
-
31
-
-
79955158683
-
-
Systemic Administration of PRO051 in Duchenne's Muscular Dystrophy
-
Goemans NM, Tulinius M, van den Akker JT, Burm BE, Ekhart PF, et al. (2011) pp. 1513-1522 Systemic Administration of PRO051 in Duchenne's Muscular Dystrophy.
-
(2011)
, pp. 1513-1522
-
-
Goemans, N.M.1
Tulinius, M.2
van den Akker, J.T.3
Burm, B.E.4
Ekhart, P.F.5
-
32
-
-
39449128867
-
Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling
-
Chakkalakal JV, Miura P, Belanger G, Michel RN, Jasmin BJ, (2008) Modulation of utrophin A mRNA stability in fast versus slow muscles via an AU-rich element and calcineurin signaling. Nucleic Acids Res 36: 826-838.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 826-838
-
-
Chakkalakal, J.V.1
Miura, P.2
Belanger, G.3
Michel, R.N.4
Jasmin, B.J.5
|