Pathogenic role of HMGB1 in SARS?

Medical Hypotheses

Volumn 63, Issue 4, 2004, Pages 691-695

  Chen, Guoqian ^a   Chen, Da Zhi ^b   Li, Jianhua ^b   Czura, Christopher J ^b   Tracey, Kevin J ^b   Sama, Andrew E ^a   Wang, Haichao ^a,b  

^a NORTH SHORE UNIVERSITY HOSPITAL   (United States)

^b 350 Community Drive ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; HERBACEOUS AGENT; HIGH MOBILITY GROUB B1 PROTEIN ANTIBODY; HIGH MOBILITY GROUP B1 PROTEIN; PROTEIN ANTIBODY; PYRUVIC ACID DERIVATIVE; PYRUVIC ACID ETHYL ESTER; UNCLASSIFIED DRUG;

ARTHRITIS; CELL ACTIVATION; CELL DEATH; CHINESE HERB; DRUG FORMULATION; ENDOTOXEMIA; HUMAN; HYPOTHESIS; IMMUNOCOMPETENT CELL; INFECTION PREVENTION; LUNG INJURY; MACROPHAGE; MONOCYTE; NONHUMAN; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; RESPIRATORY FAILURE; REVIEW; RHEUMATOID ARTHRITIS; SEPSIS; SEVERE ACUTE RESPIRATORY SYNDROME; VIRUS INFECTION;

EID: 8444242088     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.01.037     Document Type: Article

References (21)

1. Jia W., Gao W. Is traditional Chinese medicine useful in the treatment of SARS? Phytother. Res. 17(7):2003;840-841
2. Yang H., Ochani M., Li J., et al. Reversing established sepsis with antagonists of endogenous HMGB1. Proc. Natl. Acad. Sci. USA. 101(1):2004;296-301
3. Wang H., Bloom O., Zhang M., et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science. 285(5425):1999;248-251
4. Scaffidi P., Misteli T., Bianchi M.E. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature. 418(6894):2002;191-195
5. Wang H., Yang H., Czura C.J., Sama A.E., Tracey K.J. HMGB1 as a late mediator of lethal systemic inflammation. Am. J. Respir. Crit. Care Med. 164(10):2001;1768-1773
6. Wang H., Vishnubhakat J.M., Bloom O., et al. Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes. Surgery. 126(2):1999;389-392
7. Rendon-Mitchell B., Ochani M., Li J., et al. IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism. J. Immunol. 170(7):2003;3890-3897
8. Kokkola R., Sundberg E., Ulfgren A.K., et al. High mobility group box chromosomal protein 1: a novel proinflammatory mediator in synovitis. Arthritis Rheum. 46(10):2002;2598-2603
9. Taniguchi N., Kawahara K., Yone K., et al. High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum. 48(4):2003;971-981
10. Pullerits R., Jonsson I.M., Verdrengh M., et al. High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis. Arthritis Rheum. 48(6):2003;1693-1700
11. Wang H, Czura C.J., Tracey K.J. HMGB1. Thomson A, Lotze MT The cytokine handbook. 4th ed.:2003;913-923 Oxford, Academic Press
12. Wang H., Yang H., Tracey K.J. Extracellular role of HMGB1 in inflammation and sepsis. J. Int. Med. 255(3):2004;320-331
13. Abraham E., Arcaroli J., Carmody A., Wang H., Tracey K.J. HMG-1 as a mediator of acute lung inflammation. J. Immunol. 165(6):2000;2950-2954
14. Ulloa L., Ochani M., Yang H., et al. Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proc. Natl. Acad. Sci. USA. 99(19):2002;12351-12356
15. Kokkola R., Li J., Sundberg E., et al. Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity. Arthritis Rheum. 48(7):2003;2052-2058
16. Wang H., Czura C.J., Tracey K.J. Lipid unites dissipate syndromes of sepsis. Nat. Med. 10(2):2004;124-125
17. Herbal supplement. Available from: http://www.china.org.cn/english/ features/sars/63785.htm
18. Walgate R. Severe immune response kills SARS victims. New Sci. 2003;http://www.newscientist.com/news/news.jsp?id=ns99993693
19. Franks T.J., Chong P.Y., Chui P., et al. Lung pathology of severe acute respiratory syndrome (SARS): a study of 8 autopsy cases from Singapore. Hum. Pathol. 34(8):2003;743-748
20. Ding Y., Wang H., Shen H., et al. The clinical pathology of severe acute respiratory syndrome (SARS): a report from China. J. Pathol. 200(3):2003;282-289
21. Lang Z., Zhang L., Zhang S., et al. Pathological study on severe acute respiratory syndrome. Chin. Med. J. (Engl.). 116(7):2003;976-980