The homozygote AA genotype of the α 1-antichymotrypsin gene may confer protection against early-onset Parkinson's disease in women

Parkinsonism and Related Disorders

Volumn 10, Issue 8, 2004, Pages 469-473

  Lin, J J ^a,b   Yueh, K C ^a   Chang, C Y ^a   Chen, C H ^c   Lin, S Z ^d  

^a Chu Shang Show Chwan Hospital   (Taiwan)

^b Chung Shan Hospital   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

1 Antichymotrypsin; Genetic polymorphism; Parkinson's disease; Taiwanese

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PARKINSON DISEASE; PRIORITY JOURNAL;

AGE OF ONSET; AGED; ALLELES; ALPHA 1-ANTICHYMOTRYPSIN; CASE-CONTROL STUDIES; DNA; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENOTYPE; HOMOZYGOTE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TAIWAN;

EID: 8444240424     PISSN: 13538020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2004.06.001     Document Type: Article

References (41)

1. T. Foltynie, S. Sawcer, C. Brayne, and R.A. Barker The genetic basis of Parkinson's disease J Neurol Neurosurg Psychiatry 73 2002 363 370
2. J.R. Vaughan, M.B. Davis, and N.W. Wood Genetics of parkinsonism: a review Ann Hum Genet 65 2001 111 126
3. P. Teismann, P. Tieu, O. Cohen, D.K. Choi, D.C. Wu, and D. Marks Pathogenic role of glial cell in Parkinson's disease Mov Disord 18 2003 121 129
4. P.L. McGeer, K. Yasojima, and E.G. McGeer Inflammation in Parkinson's disease Adv Neurol 86 2001 83 89
5. P.L. McGeer, S.S. Itagaki, B.E. Boyes, and E.G. McGeer Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's disease and Alzheimer's disease brains Neurology 38 1988 1285 1291
6. B. Liu, J.W. Jiang, B.C. Wilson, L. Du, S.N. Yang, and J.Y. Wang Systemic infusion of naloxone reduces degeneration of substantia nigral dopaminergic neurons induced by intranigral injection of lipopolysaccharide J Pharmocol Expl Ther 295 2000 125 132
7. A.J. Herrera, A. Castao, J.L. Venero, J. Cano, and A. Machado The single intranigral injection of LPS as a new model for studying the selective effects of inflammatory reaction on dopaminergic system Neurobiol Dis 7 2000 429 447
8. M. Mogi, M. Harada, P. Riederer, H. Narabayashi, K. Fujita, and T. Nagatsu Tumor necrosis factor-α (TNF-α) increase both in the brain and in the cerebrospinal fluid from parkinsonian patients Neuosci Lett 165 1994 208 210
9. M. Mogi, M. Harada, T. Kondo, P. Riederer, H. Inagaki, and M. Minami Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients Neuosci Lett 180 1994 147 150
10. K.I. Andreasson, A. Savonenko, S. Vidensky, J.J. Goeliner, Y. Zhang, and A. Shaffer Age-dependent cognitive deficit and neuronal apotosis in cyclooxygenase-2 transgenic mice J Neurosci 21 2001 8198 8209
11. P. Teismann, K. Tieu, D.K. Choi, D.C. Wu, A. Naini, and S. Hunot Cyclooxygnease-2 is instrumental in Parkinson's disease neurodegeneration PNAS 100 2003 5473 5478
12. H. Chen, S.M. Zhang, M.A. Hermán, M.A. Schwarzschild, W.C. Willet, and G.A. Colditz Nonsteroidal anti-inflammatory drugs and the risk of Parkinson's disease Arch Neurol 60 2003 1059 1064
13. J. Travis, and G.S. Salvesen Human plasma proteinase inhibitor Ann Rev Biochem 52 1983 655 709
14. 1-antichymotrypsin J Med 16 1985 101 127
15. 1-antichymotripsin as a possible biochemical marker for Alzheimer-type dementia Ann Neurol 28 1990 561 567
16. 1-antichymotrypsin polymorphism Brain Res 759 1997 153 159
17. 1-antichymotrypsin gene polymorphismi and susceptibility to Parkinson's disease Neurology 52 1999 297 301
18. 1-antichymotrypsin A-allele in German Parkinson's disease patient J Neural Transm 106 1999 729 736
19. Y.C. Wang, H.C. Liu, T.Y. Liu, C.J. Hong, and S.J. Tsai Genetic association analysis of alpha-1-antichymotrypsin polymorphism in Parkinson's disease Eur Neurol 45 2001 254 256
20. J. Wang, C.Y. Zhao, Y.M. Si, Z.L. Liu, B. Chen, and L. Yu ACT and UCH-L1 polymorphism in Parkinson's disease and age of onset Mov Disord 17 2002 767 771
21. S.E. Daniel, and A.J. Lees Parkinson's disease Society Brain Bank, London: Overview and research J Neurol Transm 39 Suppl. 1993 165 172
22. 1-antichymotrypsin polymorphism Nat Genet 10 1995 486 488
23. J.J. Lin, K.C. Yeuh, D.C. Chang, and S.Z. Lin Association between genetic polymorphism of angiotensin converting enzyme gene and Parkinson's disease J Neurol Sci 199 2002 25 29
24. J.J. Lin, K.C. Yeuh, D.C. Chang, C.Y. Chang, and Y.H. Yeh The homozygote 10/10-copy genotype of variable number tandem repeat dopamine transporter gene confers protection against Parkinson's disease J Neurol Sci 209 2003 87 92
25. 1-antichymotrypsin deficiency Am J Hum Genet 55 1994 126 133
26. 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease Cell 52 1988 487 501
27. 1-antichymotrypsin in senile dementia of the Alzheimer type J Clin Exp Med 145 1988 907 908
28. 1-antichymotrypsin level in cerebrospinal fluid is closely associated with late onset Alzheimer's disease Intern Med 34 1995 481 484
29. J. Thome, A. Baumer, Kornhuler, M. Rosler, and P. Riederer α1-antichymotrypsin bi-allele polymorphism, apolipoprotein-E tri-allele polymorphism and genetic risk for Alzheimer's syndrome J Neural Transm Park Dis Dement Sect 10 1995 207 212
30. 1-antichymotrypsin A allele and Alzheimer's disease Neurology 48 1997 1313 1316
31. 1-antichymotrypsin polymorphism. Alzheimer's disease and allele epsilon 4 of apolipoprotei E Neurology 47 1996 1575 1577
32. 1-antichymotrypsin and IL-1 beta are not increased in CSF or serum in Alzheimer's disease Neurobiol Aging 15 1994 313 317
33. 1-antichymotrypsin is not a useful for marker of Alzheimer's disease or dementia in Parkinson's disease J Neural Transm Park Dis Dement Sect 6 1993 145 149
34. Z. Zhang, and G.C. Roman Worldwide occurrence of Parkinson's disease: an updated review Neuroepidemiology 12 1993 195 208
35. R. Maywuz, J. Denaro, N. Hemenegildo, K. Marder, M.X. Tang, and L.J. Cote A population-based investigation of Parkinson's disease with and without dementia. Relationship to age and gender Arch Neurol 49 1992 49 57
36. M. Behari, A.K. Srivastava, R.R. Das, and R.M. Pandey Risk factors of Parkinson's disease in Indian patients J Neurol Sci 190 2001 49 55
37. G.F. Wooten, L.J. Currie, V.E. Bovbjerg, J.K. Lee, and J. Patrie Are men at greater risk for Parkinson's disease than women? J Neurol Neurosurg Psychiatry 75 2004 637 639
38. N.C. Inestrosa, M.P. Marzola, and A.B. Bonnefont Cellar and molecular basis for estrogen's neuroprotectoin. Potential relevance for Alzheimer's disease Mol Neurobiol 17 1998 73 86
39. K. Kompoliti Estrogen and movement disorders Clin Neuropharmacol 22 1999 318 326
40. J.B. Becker Direct effect of 17βestradiol on striatum: sex differences in dopamine release Synapse 5 1990 147 164
41. K.A. Disshon, and D.E. Dluzen Estrogen as a neuromodulator of MPTP-induced neurotoxicity: effects upon striatal dopamine release Brain Res 746 1997 9 16