In vitro 1H-magnetic resonance spectroscopy of Barrett's esophageal mucosa using magic angle spinning techniques

European Journal of Gastroenterology and Hepatology

Volumn 16, Issue 11, 2004, Pages 1199-1205

  Dave, Umakant ^a,b   Taylor Robinson, Simon D ^a   Walker, Marjorie M ^a   Mahon, Marrita ^a,c   Puri, Basant K ^a   Thursz, Mark R ^a   Desouza, Nandita M ^a,d   Cox, I Jane ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b MORRISTON HOSPITAL   (United Kingdom)

^c Public Health Department   (Ireland)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Barrett's epithelium; Histological preservation; Magic angle spinning magnetic resonance spectroscopy; Squamous epithelium; Surveillance esophagoscopy

Indexed keywords

CHOLINE; CREATINE PHOSPHATE; CREATININE; LIPID; CREATINE; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; CONTROLLED STUDY; ENDOSCOPIC BIOPSY; ESOPHAGOSCOPY; ESOPHAGUS MUCOSA; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MALE; METABOLITE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SQUAMOUS EPITHELIUM; BIOPSY; CHEMISTRY; EPITHELIUM; ESOPHAGUS; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PROSPECTIVE STUDY;

ADULT; AGED; BARRETT ESOPHAGUS; BIOPSY; CHOLINE; CREATINE; EPITHELIUM; ESOPHAGOSCOPY; ESOPHAGUS; FEMALE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; PHOSPHOCREATINE; PROSPECTIVE STUDIES; TRIGLYCERIDES;

EID: 8444233939     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200411000-00019     Document Type: Article

References (18)

1. Blot WJ, Devesa SS, Kneller RW, Fraumeni JF Jr. Rising incidence of adenocarcinoma of the esophagus and gastric cardia. JAMA 1991; 265:1287-1289.
2. Cameron AJ, Ott BJ, Payne WS. The incidence of adenocarcinoma in columnar-lined (Barrett's) esophagus. N Engl J Med. 1985; 313: 857-859.
3. Spechler SJ. Barrett's esophagus: diagnosis and management. Baillière's Clin Gastroenterol 2000; 14:857-879.
4. Hayashi G, Haggitt R. The histology of Barrett's esophagus: metaplasia and dysplasia. In Sharma P, Sampliner RE (editors): Barrett's Esophagus and Esophageal Adenocarcinoma. London: Blackwell Science; 2001, pp. 80-88.
5. Ruiz-Cabello J, Cohen JS. Phospholipid metabolites as indicators of cancer cell function. NMR Biomed 1992; 5:226-233.
6. Mountford CE, Doran S, Lean CL, Russell P. Cancer pathology in the year 2000. Biophys Chem 1997; 68:127-135.
7. 1H MRS: correlation with histopathology. Magn Reson Med 1993; 30:525-533.
8. Delikatny EJ, Russell P, Hunter JC, Hancock R, Atkinson KH, van Haaften-Day C, et al. Proton MR and human cervical neoplasia: ex vivo spectroscopy allows distinction of invasive carcinoma of the cervix from carcinoma in situ and other preinvasive lesions. Radiology 1993; 188:791-796.
9. 31P NMR. NMR Biomed 1993; 6:187-193.
10. 31P NMR study. NMR Biomed 1999; 12:184-188.
11. Doran ST, Falk GL, Somorjai RL, Lean CL, Himmelreich U, Philips J, et al. Pathology of Barrett's esophagus by proton magnetic resonance spectroscopy and a statistical classification strategy. Am J Surg 2003; 185:232-238.
12. Cheng LL, Ma MJ, Becerra L, Ptak T, Tracey I, Lackner A, et al. Quantitative neuropathology by high resolution magic angle spinning proton magnetic resonance spectroscopy. Prac Natl Acad Sci USA 1997; 94:6408-6413.
13. 1H NMR investigation in vitro of normal and abnormal liver. Biochem Biophys Acta 1993; 1225:71-77.
14. 1H MRS choline in the brain: correlation with in vitro chemistry/histology. Life Sci 1996; 58:1929-1935.
15. Somerville M, Milne R. Surveillance of Barrett's esophagus. Development and Evaluation Committee Report. Wessex Institute for Health Research and Development. Southampton: University of Southampton; 1999, vol. 102, pp. 1-37.
16. Cameron AJ, Carpenter HA. Barrett's esophagus, high-grade dysplasia and early adenocarcinoma: a pathological study. Am J Gastroenterol 1997; 92:586-591.
17. Falk GW. Unresolved issues in Barrett's esophagus in the new millennium. Dig Dis Sci 2000; 18:27-42.
18. 1H NMR spectroscopy in organs and tissues using slow magic angle spinning. Magn Reson Med 2001; 46:213-218.