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Lancet
Volumn 364, Issue 9447, 2004, Pages 1738-1739
A novel drug target in Alzheimer's disease
Author keywords

[No Author keywords available]
Indexed keywords

BETA SECRETASE; CHOLINESTERASE INHIBITOR;
EID: 8444226291     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(04)17415-1     Document Type: Note
Times cited : (8)
References (12)
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  • 2
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  • 3
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    • Strategies for disease modification in Alzheimer's disease
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  • 4
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    • BACE2, a β-secretase homolog, cleaves at the β site and within the amyloid-β region of the amyloid-β precursor protein
    • Farzan M, Schnitzler CE, Vasilieva N, Leung D, Choe H. BACE2, a β-secretase homolog, cleaves at the β site and within the amyloid-β region of the amyloid-β precursor protein. Proc Natl Acad Sci USA. 97:2000;9712-9717
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  • 5
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    • Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric
    • Kumar-Singh S, Cras P, Wang R, et al. Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric. Am J Pathol. 161:2002;507-520
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  • 6
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    • De Strooper B. Aph-1, Pen-2, and nicastrin with presenilin generate an active gamma-secretase complex. Neuron. 38:2003;9-12
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    • De Strooper, B.1
  • 7
    • 17344388652 scopus 로고    scopus 로고
    • BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain: Implications for Alzheimer's disease therapeutics
    • Roberds SL, Anderson J, Basi G, et al. BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain: implications for Alzheimer's disease therapeutics. Hum Molec Genet. 10:2001;1317-1324
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  • 8
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    • Reticulon family members modulate BACE1 activity and amyloid-β peptide generation
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  • 10
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    • Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients
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  • 11
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.