Tenascin C expression is upregulated in pancreatic cancer and correlates with differentiation

Journal of Clinical Pathology

Volumn 57, Issue 11, 2004, Pages 1151-1155

  Juuti, A ^a   Nordling, S ^b   Louhimo, J ^a   Lundin, J ^a   Haglund, C ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

FORMALDEHYDE; MONOCLONAL ANTIBODY; PARAFFIN; TENASCIN;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BREAST CANCER; CANCER EPIDEMIOLOGY; CANCER GRADING; CANCER STAGING; CANCER SURVIVAL; CELL DIFFERENTIATION; COLORECTAL CANCER; CORRELATION ANALYSIS; EMBRYO DEVELOPMENT; FEMALE; GENDER; HISTOPATHOLOGY; HUMAN; IMMUNOREACTIVITY; LYMPH NODE; MAJOR CLINICAL STUDY; MALE; METASTASIS; PANCREAS CANCER; PANCREAS CARCINOMA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; STAINING; STATISTICAL ANALYSIS; TISSUE DISTRIBUTION; TISSUE FIXATION; TUMOR GROWTH; TUMOR LOCALIZATION; TUMOR VOLUME; UTERINE CERVIX CANCER; VATER PAPILLA CARCINOMA; WOUND HEALING;

ADENOCARCINOMA; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; SEX FACTORS; TENASCIN; UP-REGULATION;

EID: 8444224306     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2003.015818     Document Type: Article

References (27)

1. Erickson HP, Bourdon MA. Tenascin: an extracellular matrix protein prominent in specialized embryonic tissues and tumors. Annu Rev Cell Biol 1989;5:71-92.
2. Schalkwijk J, Van Vlijmen I, Oosterling B, et al. Tenascin expression in hyperproliferative skin diseases. Br J Dermatol 1991;124:13-20.
3. Hanamura N, Yoshida T, Matsumoto E, et al. Expression of fibronectin and tenascin-C mRNA by myofibroblasts, vascular ceils and epithelial cells in human colon adenomas and carcinomas. Int J Cancer 1997;73:10-15.
4. Soini Y, Pääkkö P, Virtanen I, et al. Tenascin in salivary gland tumours. Virchows Arch A Pathol Anat Histopathol 1992;421:217-22.
5. Koukoulis GK, Gould VE, Bhaltacharyya A, et al. Tenascin in normal, reactive, hyperplastic, and neoplastic tissues: biologic and pathologic implications. Hum Pathol 1991;22:636-43.
6. Mackie EJ, Halfter W, Liverani D. Induction of tenascin in healing wounds. J Cell Biol 1988;107:2757-67.
7. Wallner K, Li C, Shah PK, et al. Tenascin-C is expressed in macrophage-rich human coronary atherosclerotic plaque. Circulation 1999;99:1284-9.
8. Linder S, Blásjö M, von Rosen A, et al. Pattern of distribution and prognostic value of angiogenesis in pancreatic duct carcinoma: a semiquantitative immunohistochemical study of 45 patients. Pancreas 2001;22:240-7.
9. Karademir S, Sökmen S, Terzi C, et al. Tumor angiogenesis as a prognostic predictor in pancreatic cancer. J Hepatobiliary Pancreat Surg 2000;7:489-95.
10. Jahkola T, Toivonen T, Virtanen I, et al. Tenascin-C expression in invasion border of early breast cancer: a predictor of local and distant recurrence. Br J Cancer 1998;78:1507-13.
11. Emoto K, Yamada Y, Sawada H, et al. Annexin II overexpression correlates with stromal tenascin-C overexpression: a prognostic marker in colorectal carcinoma. Cancer 2001;92:1419-26.
12. Pilch H, Schäffer U, Schlenger K, et al. Expression of tenascin in human cervical cancer-association of tenascin expression with clinicopathological parameters. Gynecol Oncol 1999;73:415-21.
13. Vaidya P, Yosida T, Sakakura T, et al. Combined analysis of expression of c-erbB-2, Ki-67 antigen, and tenascin provides a better prognostic indicator of carcinoma of the papilla of Vater. Pancreas 1996;12:196-201.
14. Juhasz A, Bardos H, Repassy G, et al. Characteristic distribution patterns of tenascin in laryngeal and hypapharyngeal cancers. Laryngoscope 2000;110:84-92.
15. Atula T, Hedström J, Finne P, et al. Tenascin-C expression and its prognostic significance in oral and pharyngeal squamous cell carcinoma. Anticancer Res 2003;23:3051-6.
16. Kressner U, Lindmark G, Tomasini-Johansson B, et al. Stromal tenascin distribution as a prognostic marker in colorectal cancer. Br J Cancer 1997;76:526-30.
17. Wiksten JP, Lundin J, Nordling S, et al. Tenascin-C expression correlates with prognosis in gastric cancer. Oncology 2003;64:245-50.
18. Sobin LHW, ed. TNM classification of malignant tumours, 5 ed. New York, NY: Wiley-Liss Inc, 1997.
19. Linder S, Castaños-Velez E, von Rosen A, et al. Immunohistochemical expression of extracellular matrix proteins and adhesion molecules in pancreatic carcinoma. Hepatogastroenterology 2001;48:1321-7.
20. Midwood KS, Schwarzbauer JE. Tenascin-C modulates matrix contraction via focal adhesion kinase- and Rho-mediated signaling pathways. Mol Biol Cell 2002;13:3601-13.
21. Wenk MB, Midwood KS, Schwarzbauer JE. Tenascin-C suppresses Rho activation. J Cell Biol 2000;150:913-20.
22. Zagzag D, Friedlander DR, Dosik J, et al. Tenascin-C expression by angiogenic vessels in human astrocytomas and by human brain endothelial cells in vitro. Cancer Res 1996;56:182-9.
23. Jones PL, Cowan KN, Rabinovitch M. Tenascin-C, proliferation and subendothelial fibranectin in progressive pulmonary vascular disease. Am J Pathol 1997;150:1349-60.
24. Mackie EJ, Tucker RP, Halfter W, et al. The distribution of tenascin coincides with pathways of neural crest cell migration. Development 1988;102:237-50.
25. Ishihara A, Yoshida T, Tamaki H, et al. Tenascin expression in cancer cells and stroma of human breast cancer and its prognostic significance. Clin Cancer Res 1995;1:1035-41.
26. Shiraishi T, Kato H, Komada S, et al. Tenascin expression and postnatal development of the human prostate. Int J Dev Biol 1994;38:391-5.
27. Borsi L, Carnemolla B, Ponassi M, et al. Steady-state levels of different tenascin mRNAs in various normal human tissues. Cell Biol Int 1993;17:325-9.