Determination of residual ractopamine concentrations by enzyme immunoassay in treated pig's tissues on days after withdrawal

Meat Science

Volumn 90, Issue 3, 2012, Pages 755-758

  Pleadin, Jelka ^a   Perši, Nina ^a   Vulić, Ana ^a   Milić, Dinka ^b   Vahčić, Nada ^c  

^a CROATIAN VETERINARY INSTITUTE   (Croatia)

^b Dubravica Swine Farm Ltd   (Croatia)

^c UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

ELISA; Pig; Ractopamine; Residues; Tissues

Indexed keywords

AFTER-TREATMENT; BODY MASS; ELISA; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL ANIMALS; EXPERIMENTAL GROUPS; HEART TISSUES; PIG; QUANTITATIVE SCREENING; RACTOPAMINE; RELATIVE STANDARD DEVIATIONS; RESIDUES; TISSUE CONCENTRATIONS;

ENZYMES; MAMMALS; MUSCLE; TISSUE;

HISTOLOGY;

ANIMALIA; SUIDAE;

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DRUG RESIDUE; PHENETHYLAMINE DERIVATIVE; RACTOPAMINE;

ANIMAL; ARTICLE; BRAIN; BRAIN LEVEL; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART MUSCLE; KIDNEY; LIVER; MEAT; METHODOLOGY; SKELETAL MUSCLE; SWINE;

ADRENERGIC BETA-AGONISTS; ANIMALS; BRAIN; BRAIN CHEMISTRY; DRUG RESIDUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; KIDNEY; LIVER; MEAT; MUSCLE, SKELETAL; MYOCARDIUM; PHENETHYLAMINES; SWINE;

EID: 84355161978     PISSN: 03091740     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meatsci.2011.11.007     Document Type: Article

References (28)

1. Act on Animal Welfare No.135 Official gazette of the Republic of Croatia 2006.
2. Anderson D.B., Moody D.E., Hancock D.L. Beta adrenergic agonists. Encyclopedia of animal science 2009, 104-107. Marcel Dekker, Inc., New York. W.G. Pond, A.W. Bell (Eds.).
3. Anderson D.B., Veenhuizen E.L., Wagner J.F., Wray M.I., Mowrey D.H. The effect of ractopamine hydrochloride on nitrogen retention, growth performance, and carcass composition of beef cattle. Journal of Animal Science 1989, 67(Suppl. 1):222.
4. Apple J.K., Rincker P.J., McKieth F.K., Carr S.N., Armstrong T.A., PAS, et al. Meta-analysis of the ractopamine response in finishing swine. The Professional Animal Scientist 2007, 23:179-196.
5. Armstrong T.A., Ivers D.J., Wagner J.R., Anderson D.B., Weldon W.C., Berg E.P. The effect of dietary ractopamine concentration and duration of feeding on growth performance, carcass characteristics, and meat quality of finishing pigs. Journal of Animal Science 2004, 82:3245-3253.
6. Bergen W.G., Johnson S.E., Skjaerlund D.M., Merkel R.A., Anderson D.B. The effect of ractopamine on skeletal muscle metabolism in pigs. Federation Proceedings 1987, 46:1021.
7. Dalidowicz J.E., Thomson T.D., Babbitt G.E. Ractopamine hydrochloride, a phenethanolamine repartitioning agent: Metabolism and tissue residues. Xenobiotics and food-producing animals 1992, 234-243. ACS Symposium Series 503, American Chemical Society, Washington. D.H. Hutson, D.R. Hawkins, G.D. Paulson, C.B. Struble (Eds.).
8. Dalidowicz, J. E., Thomson, T. D., & Herberg, R. J. (1986). 14C-ractopamine HCl balance - excretion study in swine, Unpublished Report No. ABC-0330 from Lilly Research Laboratories, Division of Eli Lilly and Company, Greenfield, Indiana, USA.
9. Elliot C.T., Thompson C.S., Arts C.J.M., Crooks S.R.H., van Baak M.J., Verheij E.R., et al. Screening and confirmatory determination of ractopamine residues in calves treated with growth promoting doses of the β-agonist. Analyst 1998, 123:1103-1107.
10. Elliott C.T., Baxter A., Haasnoot W., Lommen A., McCaughey W.J. Development of a dual label time-resolved flouroimmunoassay for the detection of β-agonists in cattle urine. Food and Agricultural Immunology 1996, 8:219-227.
11. Gaudin V., Sanders P., Gowik P., Uhlig S. Guide for analytical validation of screening methods 2007, Federal office of consumer protection and food safety, BVL Berlin.
12. Haasnoot W., Stouten P., Lommen A., Cazemier G., Hooijerink D., Schilt R. Determination of fenoterol and ractopamine in urine by enzyme immunoassay. Analyst 1994, 119:2675-2680.
13. MacNeil, J. D. & Soback, S. (2004). Ractopamine hydrochloride. FAO Food and Nutrition Paper, FAO FNP 41/16.
14. Martinez-Navarro J.F. Food poisoning related to consumption of illicit beta-agonist in liver. Lancet 1990, 336:1311.
15. Merkel R.A., Dickerson P.S., Johnson S.E., Burnett A.L., Schroeder A.L., Bergen W.G., et al. The effect of ractopamine on lipid metabolism in pigs. Federation Proceedings 1987, 46:1177.
16. Mitchell A.D., Solomon M.B., Steele N.C. Response of low and high protein select lines of pigs to the feeding of the beta-adrenergic agonist ractopamine (phenethanolamine). Journal of Animal Science 1990, 68:3226-3232.
17. Moody D.E., Hancock D.L., Anderson D.B. Phenethanolamine repartitioning agents. Farm animal metabolism and nutrition 2000, 65-96. CAB International, New York. D'Mello (Ed.).
18. Peterla T.A., Scanes C.G. Effect of β-adrenergic agonists on lipolysis and lipogenesis by porcine adipose tissue in vitro. Journal of Animal Science 1990, 68:1024-1029.
19. Pulce C., Lamaison D., Keck G., Bostvironnois C., Nicolas J., Descotes J. Collective and human food poisonings by clenbuterol residues in veal liver. Veterinary and Human Toxicology 1991, 33:480-481.
20. Qiang Z., Shentu F., Wang B., Wang J., Chang J., Shen J. Residue depletion of ractopamine and its metabolites in swine tissues, urine, and serum. Journal of Agricultural and Food Chemistry 2007, 55:4319-4326.
21. Shelver W.L., Smith D.J. Determination of ractopamine in cattle and sheep urine samples using an optical biosensor analysis: Comparative study with HPLC and ELISA. Journal of Agricultural and Food Chemistry 2003, 51:3715-3721.
22. Smith D.J., Feil V.J., Huwe J.K., Paulson G.D. Metabolism and disposition of ractopamine hydrochloride by turkey poults. Drug Metabolism and Disposition 1993, 21:624-633.
23. Smith D.J., Shelver W.L. Tissue residues of ractopamine and urinary excretion of ractopamine and metabolites in animals treated for 7 days with dietary ractopamine. Journal of Animal Science 2002, 80:1240-1249.
24. Thompson C.S., Haughey S.A., Traynor I.M., Fodey T.L., Elliott C.T., Antignac J.-P., et al. Effective monitoring for ractopamine residues in samples of animal origin by SPR biosensor and mass spectrometry. Analytica Chimica Acta 2008, 608:217-225.
25. Turberg M.P., Macy T.D., Lewis J.J., Coleman M.R. Determination of ractopamine hydrochloride in swine and turkey tissues by liquid chromatography with coulometric detection. Journal of AOAC International 1995, 78:1394-1402.
26. Veenhuizen E.L., Schmiegel K.K., Waitt W.P., Anderson D.B. Lipolytic, growth, feed efficiency and carcass response to phenethanolamines in swine. Journal of Animal Science 1987, 65:130.
27. Watkins L.E., Jones D.J., Mowrey H., Anderson D.B., Veenhuizen E.L. The effect of various levels of ractopamine hydrochloride on the performance and carcass characteristics of finishing swine. Journal of Animal Science 1990, 68:3588-3595.
28. Williams N.H., Cline T.R., Schinckel A.P., Jones D.J. The impact of ractopamine, energy intake, and dietary fat on finisher pig growth performance and carcass merit. Journal of Animal Science 1994, 72:3152-3162.