Early parenchymal contrast extravasation predicts subsequent hemorrhage progression, Clinical deterioration, and need for surgery in patients with traumatic cerebral contusion

Journal of Trauma - Injury, Infection and Critical Care

Volumn 71, Issue 6, 2011, Pages 1593-1599

  Huang, Abel Po Hao ^a   Lee, Chung Wei ^a   Hsieh, Hong Jen ^a   Yang, Chi Cheng ^c   Tsai, Yi Hsin ^a   Tsuang, Fon Yih ^a   Kuo, Lu Ting ^a   Chen, Yuan Shen ^a   Tu, Yong Kwang ^a   Huang, Sheng Jean ^a   Liu, Hon Man ^a   Tsai, Jui Chang ^a,b  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Blood brain barrier; Computed tomography; Contrast extravasation; Contusion; Head trauma; Perfusion

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CONTUSION; BRAIN EDEMA; BRAIN HEMORRHAGE; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST MEDIUM EXTRAVASATION; DETERIORATION; DISEASE COURSE; FEMALE; FOLLOW UP; GLASGOW COMA SCALE; HIGH RISK PATIENT; HUMAN; MALE; OBSERVATIONAL STUDY; PARENCHYMAL CONTRAST MEDIUM EXTRAVASATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; TRAUMATIC CEREBRAL CONTUSION; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; BRAIN INJURIES; COHORT STUDIES; CONTRAST MEDIA; CRITICAL CARE; DECOMPRESSION, SURGICAL; DISEASE PROGRESSION; EARLY DIAGNOSIS; EXTRAVASATION OF DIAGNOSTIC AND THERAPEUTIC MATERIALS; FEMALE; FOLLOW-UP STUDIES; GLASGOW COMA SCALE; HEMATOMA, EPIDURAL, CRANIAL; HUMANS; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; NEEDS ASSESSMENT; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; SURVIVAL ANALYSIS; TAIWAN; TOMOGRAPHY, X-RAY COMPUTED; TRAUMA CENTERS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84255170190     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e31822c8865     Document Type: Article

References (23)

1. Chang EF, Meeker M, Holland MC. Acute traumatic intraparenchymal hemorrhage: risk factors for progression in the early post-injury period. Neurosurgery. 2006;58:647-656.
2. Chieregato A, Fainardi E, Morselli-Labate AM, et al. Factors associated with neurological outcome and lesion progression in traumatic subarachnoid hemorrhage patients. Neurosurgery. 2005;56:671-680.
3. Narayan RK, Maas AI, Servadei F, et al. Progression of traumatic intracerebral hemorrhage: a prospective observational study. J Neurotrauma. 2008;25:629-639. (Pubitemid 351918434)
4. Oertel M, Kelly DF, McArthur D, et al. Progressive hemorrhage after head trauma: predictors and consequences of the evolving injury. J Neurosurg. 2002;96:109-116. (Pubitemid 34229995)
5. Allard CB, Scarpelini S, Rhind SG, et al. Abnormal coagulation tests are associated with progression of traumatic intracranial hemorrhage. J Trauma. 2009;67:959-967.
6. Cohen MJ, Brohi K, Ganter MT, Manley GT, Mackersie RC, Pittet JF. Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway. J Trauma. 2007;63:1254-1261.
7. Stein SC, Chen XH, Sinson GP, Smith DH. Intravascular coagulation: a major secondary insult in nonfatal traumatic brain injury. J Neurosurg. 2002;97:1373-1377. (Pubitemid 35424293)
8. Servadei F, Murray GD, Penny K, et al. The value of the "worst" computed tomographic scan in clinical studies of moderate and severe head injury. European Brain Injury Consortium. Neurosurgery. 2000;46:70-75.
9. Delgado Almandoz JE, Yoo AJ, Stone MJ, et al. The spot sign score in primary intracerebral hemorrhage identifies patients at highest risk of in-hospital mortality and poor outcome among survivors. Stroke. 2010;41:54-60.
10. Delgado Almandoz JE, Yoo AJ, Stone MJ, et al. Systematic characterization of the computed tomography angiography spot sign in primary intracerebral hemorrhage identifies patients at highest risk for hematoma expansion: the spot sign score. Stroke. 2009;40:2994-3000.
11. Powers WJ. Intracerebral hemorrhage and head trauma: common effects and common mechanisms of injury. Stroke. 2010;41:S107-S110.
12. Chieregato A, Fainardi E, Servadei F, et al. Centrifugal distribution of regional cerebral blood flow and its time course in traumatic intracerebral hematomas. J Neurotrauma. 2004;21:655-666. (Pubitemid 38880238)
13. von Oettingen G, Bergholt B, Gyldensted C, Astrup J. Blood flow and ischemia within traumatic cerebral contusions. Neurosurgery. 2002;50: 781-788.
14. Hallevi H, Abraham AT, Barreto AD, Grotta JC, Savitz SI. The spot sign in intracerebral hemorrhage: the importance of looking for contrast extravasation. Cerebrovasc Dis. 2010;29:217-220.
15. Vo KD, Santiago F, Lin W, Hsu CY, Lee Y, Lee JM. MR imaging enhancement patterns as predictors of hemorrhagic transformation in acute ischemic stroke. AJNR Am J Neuroradiol. 2003;24:674-679. (Pubitemid 36460739)
16. Rodríguez-Baeza A, Reina-de la Torre F, Poca A, Martí M, Garnacho A. Morphological features in human cortical brain microvessels after head injury: a three-dimensional and immunocytochemical study. Anat Rec A Discov Mol Cell Evol Biol. 2003;273:583-593. (Pubitemid 37408351)
17. Chakraborty S, Blacquiere D, Lum C, Stotts G. Dynamic nature of the CT angiographic "spot sign." Br J Radiol. 2010;83:e216-e219.
18. Shlosberg D, Benifla M, Kaufer D, Friedman A. Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury. Nat Rev Neurol. 2010;6:393-403.
19. Lescot T, Degos V, Zouaoui A, Préteux F, Coriat P, Puybasset L. Opposed effects of hypertonic saline on contusions and noncontused brain tissue in patients with severe traumatic brain injury. Crit Care Med. 2006;34:3029-3033. (Pubitemid 44808749)
20. Stein SC, Graham DI, Chen XH, Smith DH. Association between intravascular microthrombosis and cerebral ischemia in traumatic brain injury. Neurosurgery. 2004;54:687-691. (Pubitemid 38298743)
21. Hom J, Dankbaar JW, Soares BP, et al. Blood-brain barrier permeability assessed by perfusion ct predicts symptomatic hemorrhagic transformation and malignant edema in acute ischemic stroke. AJNR Am J Neuroradiol. 2011;32:41-48.
22. Zaharchuk G. Theoretical basis of hemodynamic MR imaging techniques to measure cerebral blood volume, cerebral blood flow, and permeability. AJNR Am J Neuroradiol. 2007;28:1850-1858. (Pubitemid 350174722)
23. Jander S, Schroeter M, Saleh A. Imaging inflammation in acute brain ischemia. Stroke. 2007;38:642-645. (Pubitemid 46184233)