Clot lysis time and the risk of myocardial infarction and ischaemic stroke in young women; results from the RATIO case-control study

British Journal of Haematology

Volumn 156, Issue 2, 2012, Pages 252-258

  Siegerink, Bob ^a   Meltzer, Mirjam E ^a,b   De Groot, Philip G ^b   Algra, Ale ^a,b   Lisman, Ton ^b,c   Rosendaal, Frits R ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Clot lysis time; Fibrinolysis; Ischaemic stroke; Myocardial infarction; Young women

Indexed keywords

ORAL CONTRACEPTIVE AGENT; THROMBOPLASTIN; TISSUE PLASMINOGEN ACTIVATOR;

ADULT; ARTICLE; BLOOD CLOT LYSIS; BLOOD CLOT LYSIS TIME; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CASE CONTROL STUDY; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; HEART INFARCTION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MAJOR CLINICAL STUDY; ORAL CONTRACEPTION; POPULATION RESEARCH; PRIORITY JOURNAL; RISK ASSESSMENT; SMOKING; THROMBOSIS;

ADOLESCENT; ADULT; BLOOD COAGULATION TESTS; CASE-CONTROL STUDIES; FEMALE; FIBRINOLYSIS; HUMANS; MIDDLE AGED; MYOCARDIAL INFARCTION; RISK FACTORS; STROKE; YOUNG ADULT;

EID: 84155180824     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2011.08935.x     Document Type: Article

References (22)

1. Adams, Jr, H.P., Bendixen, B.H., Kappelle, L.J., Biller, J., Love, B.B., Gordon, D.L. & Marsh, III, E.E. (1993) Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke, 24, 35-41.
2. Benchenane, K., Lopez-Atalaya, J.P., Fernandez-Monreal, M., Touzani, O. & Vivien, D. (2004) Equivocal roles of tissue-type plasminogen activator in stroke-induced injury. Trends in Neurosciences, 27, 155-160.
3. van den Bosch, M.A., Kemmeren, J.M., Tanis, B.C., Mali, W.P., Helmerhorst, F.M., Rosendaal, F.R., Algra, A. & van der Graaf, Y. (2003) The RATIO study: oral contraceptives and the risk of peripheral arterial disease in young women. Journal of Thrombosis and Haemostasis, 1, 439-444.
4. Chan, M.Y., Andreotti, F. & Becker, R.C. (2008) Hypercoagulable states in cardiovascular disease. Circulation, 118, 2286-2297.
5. Colman, R.W. & Schmaier, A.H. (1997) Contact system: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes. Blood, 90, 3819-3843.
6. Guimaraes, A.H., de Bruijne, E.L., Lisman, T., Dippel, D.W., Deckers, J.W., Poldermans, D., Rijken, D.C. & Leebeek, F.W. (2009) Hypofibrinolysis is a risk factor for arterial thrombosis at young age. British Journal of Haematology, 145, 115-120.
7. Kemmeren, J.M., Tanis, B.C., van den Bosch, M.A., Bollen, E.L., Helmerhorst, F.M., van der Graaf, Y., Rosendaal, F.R. & Algra, A. (2002) Risk of Arterial Thrombosis in Relation to Oral Contraceptives (RATIO) study: oral contraceptives and the risk of ischemic stroke. Stroke, 33, 1202-1208.
8. Kilpatrick, T.J., Matkovic, Z., Davis, S.M., McGrath, C.M. & Dauer, R.J. (1993) Hematologic abnormalities occur in both cortical and lacunar infarction. Stroke, 24, 1945-1950.
9. Lisman, T., Leebeek, F.W., Mosnier, L.O., Bouma, B.N., Meijers, J.C., Janssen, H.L., Nieuwenhuis, H.K. & de Groot, P.G. (2001) Thrombin-activatable fibrinolysis inhibitor deficiency in cirrhosis is not associated with increased plasma fibrinolysis. Gastroenterology, 121, 131-139.
10. Lisman, T., de Groot, P.G., Meijers, J.C. & Rosendaal, F.R. (2005) Reduced plasma fibrinolytic potential is a risk factor for venous thrombosis. Blood, 105, 1102-1105.
11. Lloyd-Jones, D., Adams, R.J., Brown, T.M., Carnethon, M., Dai, S., De, S.G., Ferguson, T.B., Ford, E., Furie, K., Gillespie, C., Go, A., Greenlund, K., Haase, N., Hailpern, S., Ho, P.M., Howard, V., Kissela, B., Kittner, S., Lackland, D., Lisabeth, L., Marelli, A., McDermott, M.M., Meigs, J., Mozaffarian, D., Mussolino, M., Nichol, G., Roger, V.L., Rosamond, W., Sacco, R., Sorlie, P., Roger, V.L., Thom, T., Wasserthiel-Smoller, S., Wong, N.D. & Wylie-Rosett, J. (2010) Heart disease and stroke statistics - 2010 update: a report from the American Heart Association. Circulation, 121, e46-e215.
12. Meltzer, M.E., Doggen, C.J.M., de Groot, P.G., Rosendaal, F.R. & Lisman, T. (2007) Fibrinolysis and the risk of venous and arterial thrombosis. Current Opinion Hematology, 14, 242-248.
13. Meltzer, M.E., Lisman, T., Doggen, C.J.M., de Groot, P.G. & Rosendaal, F.R. (2008) Synergistic effects of hypofibrinolysis and genetic and acquired risk factors on the risk of a first venous thrombosis. PLoS Medicine, 5, e97.
14. Meltzer, M.E., Doggen, C.J.M., de Groot, P.G., Rosendaal, F.R. & Lisman, T. (2009) Reduced plasma fibrinolytic capacity as a potential risk factor for a first myocardial infarction in young men. British Journal of Haematology, 145, 121-127.
15. Meltzer, M.E., Lisman, T., de Groot, P.G., Meijers, J.C.M., le Cessie, S., Doggen, C.J.M. & Rosendaal, F.R. (2010) Venous thrombosis risk associated with plasma hypofibrinolysis is explained by elevated plasma levels of TAFI and PAI-1. Blood, 116, 113-121.
16. Prins, M.H. & Hirsh, J. (1991) A critical review of the relationship between impaired fibrinolysis and myocardial infarction. American Heart Journal, 122, 545-551.
17. Rosendaal, F.R. (2003) Clotting and myocardial infarction: a cycle of insights. Journal of Thrombosis and Haemostasis, 1, 640-642.
18. Sharma, S.C., Vijayan, G.P., Seth, H.N. & Suri, M.L. (1978) Platelet adhesiveness, plasma fibrinogen, and fibrinolytic activity in young patients with ischaemic stroke. Journal of Neurology, Neurosurgery and Psychiatry, 41, 118-121.
19. Tanis, B.C., van den Bosch, M.A., Kemmeren, J.M., Manger Cats, V., Helmerhorst, F.M., Algra, A., van der Graaf, Y. & Rosendaal, F.R. (2001) Oral contraceptives and the risk of myocardial infarction. New England Journal Medicine, 345, 1787-1793.
20. Tsantes, A.E., Nikolopoulos, G.K., Bagos, P.G., Tsiara, C.G., Kapsimali, V., Travlou, A. & Vaiopoulos, G. (2007) Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of ischemic stroke: a meta-analysis. Blood Coagulation and Fibrinolysis, 18, 497-504.
21. Tsantes, A.E., Nikolopoulos, G.K., Bagos, P.G., Bonovas, S., Kopterides, P. & Vaiopoulos, G. (2008) The effect of the plasminogen activator inhibitor-1 4G/5G polymorphism on the thrombotic risk. Thrombosis Research, 122, 736-742.
22. Undas, A., Celinska-Lowenhoff, M., Lowenhoff, T. & Szczeklik, A. (2006) Statins, fenofibrate, and quinapril increase clot permeability and enhance fibrinolysis in patients with coronary artery disease. Journal of Thrombosis and Haemostasis, 4, 1029-1036.