Bromomaleimide-Linked Bioconjugates Are Cleavable in Mammalian Cells

ChemBioChem

Volumn 13, Issue 1, 2012, Pages 39-41

  Moody, Paul ^a,b   Smith, Mark E B ^a   Ryan, Chris P ^a   Chudasama, Vijay ^a   Baker, James R ^a   Molloy, Justin ^b   Caddick, Stephen ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Drug delivery; Fluorescent probes; In cell cleavage; Microinjection; Protein modifications

Indexed keywords

GREEN FLUORESCENT PROTEIN; MALEIMIDE DERIVATIVE; RHODAMINE;

ARTICLE; CELL CULTURE; CELL DIVISION; CONJUGATION; CYTOPLASM; FLUORESCENCE RESONANCE ENERGY TRANSFER; HELA CELL; HUMAN; HUMAN CELL; HYDROLYSIS; MAMMAL CELL; PRIORITY JOURNAL;

GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; KINETICS; MALEIMIDES; MOLECULAR STRUCTURE; RHODAMINES; TIME FACTORS;

EID: 84155174689     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201100603     Document Type: Article

References (6)

1. L. M. Tedaldi, M. E. B. Smith, R. I. Nathani, J. R. Baker, Chem. Commun. 2009, 6583-6585.
2. M. E. B. Smith, F. F. Schumacher, C. P. Ryan, L. M. Tedaldi, D. Papaioannou, G. Waksman, S. Caddick, J. R. Baker, J. Am. Chem. Soc. 2010, 132, 1960-1965.
3. C. P. Ryan, M. E. B. Smith, F. F. Schumacher, D. Grohmann, D. Papaioannou, G. Waksman, F. Werner, J. R. Baker, S. Caddick, Chem. Commun. 2011, 47, 5452-5454.
4. F. F. Schumacher, M. Nobles, C. P. Ryan, M. E. B. Smith, A. Tinker, S. Caddick, J. R. Baker, Bioconjugate Chem. 2011, 22, 132-136.
5. C. V. Smith, D. P. Jones, T. M. Guenthner, L. H. Lash, B. H. Lauterburg, Toxicol. Appl. Pharmacol. 1996, 140, 1-12.
6. J.-D. Pedelacq, S. Cabantous, T. Tran, T. C. Terwilliger, G. S. Waldo, Nat. Biotechnol. 2006, 24, 79-88.