Allodynic skin in post-herpetic neuralgia: Histological correlates

Journal of Cellular Physiology

Volumn 227, Issue 3, 2012, Pages 934-938

  Buonocore, Michelangelo ^a   Gatti, Anna Maria ^a   Amato, Georgia ^a   Aloisi, Anna Maria ^a,b   Bonezzi, Cesare ^a  

^a IRCCS   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLODYNIA; ARTICLE; CERVICAL SPINE; CLINICAL ARTICLE; CONTROLLED STUDY; DERMATOME; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; LUMBAR SPINE; MALE; NERVE FIBER; PAIN ASSESSMENT; POSTHERPETIC NEURALGIA; PRIORITY JOURNAL; SCORING SYSTEM; SKIN; SKIN BIOPSY; SKIN NERVE; THORACIC SPINE; TRIGEMINAL NERVE;

AGED; AGED, 80 AND OVER; EPIDERMIS; FEMALE; HUMANS; HYPERALGESIA; MALE; MIDDLE AGED; NERVE FIBERS; NEURALGIA, POSTHERPETIC; PAIN MEASUREMENT; PHYSICAL STIMULATION; SEVERITY OF ILLNESS INDEX;

EID: 84155174658     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22804     Document Type: Article

References (26)

1. Baron R, Saguer M. 1993. Postherpetic neuralgia. Are C-nociceptors involved in signalling and maintenance of tactile allodynia? Brain 116: 1477-1496.
2. Baron R, Saguer M. 1995. Mechanical allodynia in postherpetic neuralgia: Evidence for central mechanisms depending on nociceptive C-fiber degeneration. Neurology 45: S63-S65.
3. Baron R. 2008. Mechanisms of postherpetic neuralgia - We are hot on the scent. Pain 140: 395-396.
4. Campbell JN, Raja SN, Meyer RA, Mackinnon SE. 1988. Myelinated afferents signal the hyperalgesia associated with nerve injury. Pain 32: 89-94.
5. Campero M, Serra J, Marchettini P, Ochoa JL. 1998. Ectopic impulse generation and autoexcitation in single myelinated afferent fibers in patients with peripheral neuropathy and positive sensory symptoms. Muscle Nerve 21: 1661-1667.
6. Fields HL, Rowbotham M, Baron R. 1998. Postherpetic neuralgia: Irritable nociceptors and deafferentation. Neurobiol Dis 5: 209-227.
7. Griffin JW, McArthur JC, Polydefkis M. 2001. Assessment of cutaneous innervation by skin biopsies. Curr Opin Neurol 14: 655-659.
8. Johnson RW, Bouhassira D, Kassianos G, Leplège A, Schmader KE, Weinke T. 2010. The impact of herpes zoster and post-herpetic neuralgia on quality-of-life. BMC Med 8: 37.
9. Kennedy WR. 2004. Opportunities afforded by the study of unmyelinated nerves in skin and other organs. Muscle Nerve 29: 756-767.
10. Koltzenburg M. 2000. Neural mechanisms of cutaneous nociceptive pain. Clin J Pain 6: S131-S138.
11. Lauria G, Cornblath DR, Johansson O, McArthur JC, Mellgren SI, Nolano M, Rosenberg N, Sommer C. 2005. EFNS guidelines on the use of skin biopsy in the diagnosis of peripheral neuropathy. Eur J Neurol 12: 747-758.
12. McCarthy B, Hsieh ST, Stocks A, Hauer P, Macko C, Cornblath DR, Griffin JW, McArthur JC. 1995. Cutaneous innervation in sensory neuropathies: Evaluation by skin biopsy. Neurology 45: 1848-1855.
13. Nurmikko TJ, Bowsher D. 1990. Somatosensory findings in postherpetic neuralgia. J Neurol Neurosurg Psychiatry 53: 135-141.
14. Oaklander AL. 2001. The density of remaining nerve endings in human skin with and without postherpetic neuralgia after shingles. Pain 92: 139-145.
15. Ochoa JL. 1994. Pain mechanisms in neuropathy. Curr Opin Neurol 7: 407-414.
16. Pappagallo M, Oaklander AL, Quatrano-Piacentini AL, Clark MR, Raja SN. 2000. Heterogeneous patterns of sensory dysfunction in postherpetic neuralgia suggest multiple pathophysiological mechanisms. Anesthesiology 92: 691-698.
17. Petersen KL, Rice FL, Farhadi M, Reda H, Rowbotham MC. 2010. Natural history of cutaneous innervation following herpes zoster. Pain 150: 75-82.
18. Rowbotham MC, Fields HL. 1996. The relationship of pain, allodynia, and thermal sensation in post-herpetic neuralgia. Brain 119: 347-354.
19. Rowbotham MC, Yosipovitch G, Connolly MK, Finlay D, Forde G, Fields HL. 1996. Cutaneous innervation density in the allodynic form of postherpetic neuralgia. Neurobiol Dis 3: 205-214.
20. Samuelsson M, Leffler AS, Hansson P. 2005. Dynamic mechanical allodynia: On the relationship between temporo-spatial stimulus parameters and evoked pain in patients with peripheral neuropathy. Pain 115: 264-272.
21. Torebjörk HE, Lundberg LE, LaMotte RH. 1992. Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans. J Physiol 448: 765-780.
22. Treede RD, Handwerker HO, Baumgärtner U, Meyer RA, Magerl W. 2004. Hyperalgesia and allodynia: Taxonomy, assessment, and mechanisms. In: Brune K, Handwerker H, editors. Hyperalgesia: Molecular mechanisms and clinical implications. Seattle: IASP Press. pp. 3-15.
23. Vlckova-Moravcova E, Bednarik J, Dusek L, Toyka KV, Sommer C. 2008. Diagnostic validity of epidermal nerve fiber densities in painful sensory neuropathies. Muscle Nerve 37: 50-60.
24. Watson CP, Deck JH, Morshead C, Van der Kooy D, Evans RJ. 1991. Post-herpetic neuralgia: Further post-mortem studies of cases with and without pain. Pain 44: 105-117.
25. Woolf CJ, Shortland P, Coggeshall RE. 1992. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature 355: 75-78.
26. Zacks SI, Elliott FA, Langfitt TW. 1964. Herpetic neuritis: A light and electron microscopic study. Neurology 14: 744-750.